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Articles by Thomas Eigentler
Years of life lost in patients with a false-negative diagnosis of primary melanoma. A prospective study of the German Central Malignant Melanoma Registry involving 9063 patients over 28 years
Abstract A false-negative diagnosis of cancer can lead to a delay in effective treatment and a poorer prognosis. Here, we use the example of cutaneous melanoma to examine how many years of life are lost after a false-negative diagnosis compared to a primarily correct diagnosis. From 1996 to 2015, 9,063 patients are prospectively registered in the German Central Malignant Melanoma Registry and followed up until December 2023. A false-negative diagnosis is found in 206 (2.3%) patients.
Real-world effectiveness and safety with nivolumab plus ipilimumab or nivolumab alone in patients with or without melanoma brain metastasis: Results from the German noninterventional NICO study
1L first-line 2L+ second- or later-line ABC Anti–PD-1 Brain Collaboration ADOReg German skin cancer registry AE adverse event BOR best overall response CI confidence interval CNS central nervous system CR complete response D/C discontinuation DCR disease control rate deCOG German Dermatologic Cooperative Oncology Group ECOG PS Eastern Cooperative Oncology Group performance status eCRF electronic case report form EORTC QLQ-C30 European Organization for Research and Treatment of Cancer Quality...
Immer mehr Menschen leiden unter Hautkrebs: Woran liegt es und was ist zu tun?
© Getty Images/LordHenriVoton Die Zahl der Hautkrebsfälle steigt seit Jahren kontinuierlich an. Wir haben drei Experten befragt, wie sich dieser besorgniserregende Trend stoppen lässt. Von Silke Hofmann Eggert Stockfleth Thomas Eigentler Hauke Hohensee Heute, 20:29 Uhr In den vergangenen zwei Jahrzehnten ist die Zahl der Krankenhausbehandlungen wegen Hautkrebs extrem gestiegen. Das vermeldete das Statistische Bundesamt kürzlich.
Helmet Radio Frequency Phased Array Applicators Enhance Thermal Magnetic Resonance of Brain Tumors
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Melanoma of the central nervous system based on neurocutaneous melanocytosis in childhood: A rare but fatal condition
CMN congenital melanocytic nevi CNS central nervous system MRI magnetic resonance imaging NCM neurocutaneous melanocytosis STEP registry German Registry for Rare Pediatric Tumors 1 INTRODUCTION Neurocutaneous melanocytosis (NCM) is a very rare congenital disorder characterized by the association of leptomeningeal or parenchymatous melanocytosis, defined as a proliferation of cytologically bland melanocytic cells, and either congenital melanocytic nevi (CMN; large or giant and/or multiple) or...
Medical Needs and Therapeutic Options for Melanoma Patients Resistant to Anti-PD-1-Directed Immune Checkpoint Inhibition
This is an early access version, the complete PDF, HTML, and XML versions will be available soon. Open AccessReview by Jessica C. Hassel 1, Lisa Zimmer 2,3, Thomas Sickmann 4, Thomas K.
Advanced Radio Frequency Applicators for Thermal Magnetic Resonance Theranostics of Brain Tumors
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A Feasibility Study for Immediate Histological Assessment of Various Skin Biopsies Using Ex Vivo Confocal Laser Scanning Microscopy
This is an early access version, the complete PDF, HTML, and XML versions will be available soon.
Lipodystrophic Nonalcoholic Fatty Liver Disease Induced by Immune Checkpoint Blockade
Letters |3 March 2020 Thomas Eigentler, MD; Diana Lomberg, MD; Jürgen Machann, PhD; Norbert Stefan, MD Thomas Eigentler, MD University Hospital of Tübingen, Tübingen, Germany (T.E., D.L.) Diana Lomberg, MD University Hospital of Tübingen, Tübingen, Germany (T.E., D.L.) Jürgen Machann, PhD Institute of Diabetes Research and Metabolic Diseases (IDM) of the Helmholtz Center Munich, Tübingen, Germany (J.M.) Norbert Stefan, MD Institute of Diabetes Research and Metabolic Diseases (IDM) of the...
Wideband Self‐Grounded Bow‐Tie Antenna for Thermal MR
Abstract The objective of this study was the design, implementation, evaluation and application of a compact wideband self‐grounded bow‐tie (SGBT) radiofrequency (RF) antenna building block that supports anatomical proton (1H) MRI, fluorine (19F) MRI, MR thermometry and broadband thermal intervention integrated in a whole‐body 7.0 T system.
Efficacy of PD-1-based immunotherapy after radiologic progression on targeted therapy in stage IV melanoma
To view the full text, please login as a subscribed user or purchase a subscription. Click here to view the full text on ScienceDirect. Fig. 1 Flow chart showing the inclusion criteria and time points of assessment. ORR, objective response rate; OS, overall survival; PFS, progression-free survival; ICB, immune checkpoint blockade; CTLA-4, cytotoxic T-lymphocyte antigen 4; PD-1, programmed death 1. Fig.
Immune checkpoint blockade therapy
Immune checkpoint blockade therapy , , , Martin Röckenx Martin Röcken Search for articles by this authorCorrespondenceCorresponding author: Martin Röcken, MD, Department of Dermatology, Eberhard Karls University, Liebermeisterstr. 25, 72076 Tübingen, Germany. , MD Correspondence information about the author MD Martin Röckenx Martin Röcken Search for articles by this authorCorrespondenceCorresponding author: Martin Röcken, MD, Department of Dermatology, Eberhard Karls University, Liebermeisterstr.
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