Tom Chen
Zhejiang Sheng
Multimedia journalist, videographer, living and working in NYC.
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Articles by Tom Chen
Management of Soft Tissue and Visceral Leiomyosarcomas
1Department of Medical Oncology, Sarcoma and Bone Tumors Reference Center, A.C.Camargo Cancer Center, São Paulo, Brazil 2Sarcoma Program, Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada 3Department of Surgery, Mount Sinai Hospital, Sinai Health Systems, Toronto, Ontario, Canada 4National Leiomyosarcoma Foundation (NLMSF), Denver, Colorado 5Division of Surgical Oncology, Department of Surgery, Emory University School of Medicine and Winship Cancer...
Miles v0.1: Production-Level Post-Training
Get this paper in your agent: hf papers read 2609.08368 Don't have the latest CLI? curl -LsSf https://hf.co/cli/install.sh | bash Models citing this paper 0 No model linking this paper Cite arxiv.org/abs/2609.08368 in a model README.md to link it from this page. Datasets citing this paper 0 No dataset linking this paper Cite arxiv.org/abs/2609.08368 in a dataset README.md to link it from this page.
DeepSeek-V4 on Day 0: From Fast Inference to Verified RL with SGLang and Miles
The SGLang and Miles TeamApril 25, 2026 We are thrilled to announce Day-0 support for DeepSeek-V4 across both inference and RL training. SGLang and Miles form the first open-source stack to serve and train DeepSeek-V4 on launch day — with systems purpose-built for its hybrid sparse-attention architecture, manifold-constrained hyper-connections (mHC), and FP4 expert weights. Figure 1. Decode throughput of SGLang vs the other OSS engine on a 30K-token prompt truncated from "Dream of the Red Chamber".
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Hi Jason! Glad to see another new investor from Syracuse! I would say the best place to start is looking on the MLS or Craigslist and start analyzing deals. Even if the deal wont work out, the effort of analyzing it will help you recognize a good deal when you see it. Make sure you have specific search criteria you are interested in to filter on, otherwise your head will be spinning with all the active listings. By this I mean if you only want single family homes then dont look at Multi family.
Scaling Trust, Earning Customer Love: The Reality of AI Voice Agents
Voice remains the most human and the most demanding channel in customer experience. It's real-time, high-stakes, and emotionally nuanced. While automation has transformed email, chat, and self-service channels, voice has long resisted large-scale automation, and now large language models have offered glimpses into a more automated future.
A protocol using mixed methods for the impact analysis of the implementation of the EMPOWER project: an eHealth intervention to promote mental health and well-being in European workplaces
Introduction Mental health at the workplace has been identified as a major priority by the WHO.1 Despite its significance, international studies examining the impact of digital mental health interventions implemented in the workplace are limited, with the focus on tools implemented in healthcare organisations.2–4 Inadequate evaluation and documentation of the process of implementation make it challenging for those implementing new digital interventions to replicate positive results or...
How to Read and Understand Level 2 Market Data
KEY POINTS Level 2 market data consists of the bid and ask prices, the order size for each bid and ask price, the market participant who has placed the order, and the time and sales where you see what trades have been executed. Three common ways to interpret the level 2 market data are confirming key support and resistance levels, determinign the potential strength of those key levels, and analyzing the market liquidity if your assset.
Hormone therapy enhances anti-PD1 efficacy in premenopausal estrogen receptor-positive and HER2-negative advanced breast cancer
Keywords immunotherapy hormone therapy gonadotropin-releasing hormone agonits estrogen receptor positive/HER2 negative metastatic breast cancer luminal subtype tumor microenvironment estrogen suppression cancer immune cell infiltration Introduction Immunotherapy has revolutionized the treatment of most cancer types in the past decade.1 Among various breast cancer (BC) types, immunotherapy is proven to be effective first in triple-negative BC (TNBC) either in the neoadjuvant setting for early...
Testing and Masking Policies and Hospital-Onset Respiratory Viral Infections
Introduction Most hospitals have stopped testing all patients for SARS-CoV-2 upon admission and requiring masking. Ten hospitals in the Mass General Brigham hospital system ended both these precautions simultaneously in May 2023 but restarted masking for health care workers in January 2024 during a winter respiratory viral surge. We characterized the association of these changes with the relative incidence of hospital-onset SARS-CoV-2, influenza, and respiratory syncytial virus (RSV).
Risk On Risk Off Currencies - What It Means in Forex Trading?
KEY POINTS Risk-on/Risk-off is a term that refers to investors’ behaviour and willingness to take risks. In a risk-on environment, investors move their fund into risker currencies, while in a risk-off environemnt, the sentiment toward investing in safe-haven assets and currencies. Some risk-on currencies include AUD, CAD, and NZD. Risk-off currencies include USD, JPY,EUR, CHF, and GBP Most forex traders focus heavily on technical analysis—chart patterns, indicators, and price action.
Valid Analysis of Brain-Specific Progression-Free Survival
Radiotherapy Alone vs Preceded by Bevacizumab, Etoposide, and Cisplatin for Breast Cancer Brain Metastases Tom Wei-Wu Chen, MD, PhD; Ming-Shen Dai, MD, PhD; Ling-Ming Tseng, MD, PhD; Shin-Cheh Chen, MD, PhD; Tsu-Yi Chao, MD, PhD; Ta-Chung Chao, MD, PhD; Yuan-Ching Chang, MD, PhD; Chang-Fang Chiu, MD, PhD; Chien-Ting Liu, MD; Ching-Hung Lin, MD, PhD; Chun-Yu Liu, MD, PhD; Ya-Fang Chen, MD, PhD; Dwan-Ying Chang, MD; Jyh-Cherng Yu, MD, PhD; Kun-Ming Rau, MD, PhD; Yao-Yu Hsieh, MD, PhD; Shih-Che...
Valid Analysis of Brain-Specific Progression-Free Survival-Reply
Valid Analysis of Brain-Specific Progression-Free Survival—Reply In Reply We appreciate Armbruster et al and Yu et al for their interest and comments regarding our A-PLUS study.1 Armbruster et al point out that there is an alternative way to illustrate the benefit of the bevacizumab, cisplatin, and etoposide (BEEP) regimen in the control of patients with breast cancer brain metastasis (BCBM) by using restricted mean survival time (RMST). This is reassuring.
A case of primary pleural epithelioid hemangioendothelioma achieving stable disease with paclitaxel treatment: A case report and literature review
INTRODUCTION Epithelioid hemangioendothelioma (EHE) is an uncommon vascular tumour characterized by an intermediate malignancy and is, positioned between benign hemangioma and aggressive angiosarcoma. This disease can manifest in any body part, but primarily targets the liver, lungs, and soft tissues. It shows a higher prevalence in women than in men, typically affecting middle-aged adults.1 Notably, cases of pleural EHE are exceedingly rare, occurring in older adult men.
Whole-Brain Radiotherapy Alone vs Preceded by Bevacizumab, Etoposide, and Cisplatin for Untreated Brain Metastases From Breast Cancer: A Randomized Clinical Trial | Neuro-oncology | JAMA Oncology | JAMA Network
Whole-Brain Radiotherapy Alone vs Preceded by Bevacizumab, Etoposide, and Cisplatin for Untreated Brain Metastases From Breast Cancer: A Randomized Clinical Trial Key Points Question Does bevacizumab, etoposide, and cisplatin (BEEP) induction treatment before whole-brain radiotherapy (WBRT) extend control of brain metastasis in patients with metastatic breast cancer?
Use of Electronic Clinical Data to Track Incidence and Mortality for SARS-CoV-2-Associated Sepsis
Key Points Question How did the frequency and mortality for SARS-CoV-2–associated sepsis differ from presumed bacterial sepsis during the COVID-19 pandemic? Findings In this retrospective cohort study of 431 017 inpatient encounters at 5 Massachusetts hospitals between March 2020 and November 2022, SARS-CoV-2–associated sepsis was present in 1.5% of all admissions and 28.2% of SARS-CoV-2–positive hospitalizations, whereas presumed bacterial sepsis was present in 7.1% of hospitalizations.
Breaking time barriers: Millimeter-scale photonic simulations in minutes
Designing photonic devices relies heavily on modeling their behavior with computational simulations. These simulations often require substantial computational resources and time, particularly when dealing with large structures like millimeter-scale geometries. This bottleneck impedes the pace of innovation and increases the time-to-market for new devices. However, the power of hardware-accelerated simulation offers a paradigm shift in how we approach photonic device design.
The proteomic landscape of soft tissue sarcomas - Nature Communications
Abstract Soft tissue sarcomas (STS) are rare and diverse mesenchymal cancers with limited treatment options. Here we undertake comprehensive proteomic profiling of tumour specimens from 321 STS patients representing 11 histological subtypes. Within leiomyosarcomas, we identify three proteomic subtypes with distinct myogenesis and immune features, anatomical site distribution and survival outcomes.
The Simple ABC Correction Pattern: Identification and Trading Strategy
As prices tend to move in waves, many chart patterns are based on price wave movements. One such pattern is the simple ABC correction pattern. KEY POINTS Prices often move in waves, forming recognizable chart patterns like the Simple ABC Correction Pattern. The Simple ABC Correction Pattern provides insights into price wave corrections in the market. Utilizing this pattern can enhance your trading strategies during market corrections.
XPF activates break-induced telomere synthesis - Nature Communications
Abstract Alternative Lengthening of Telomeres (ALT) utilizes a recombination mechanism and break-induced DNA synthesis to maintain telomere length without telomerase, but it is unclear how cells initiate ALT. TERRA, telomeric repeat-containing RNA, forms RNA:DNA hybrids (R-loops) at ALT telomeres. We show that depleting TERRA using an RNA-targeting Cas9 system reduces ALT-associated PML bodies, telomere clustering, and telomere lengthening.
Revisiting Adjuvant Hormone Therapy in Premenopausal Women With Breast Cancer: Escalation and De-Escalation
The National Comprehensive Cancer Network (NCCN) and European Society for Medical Oncology (ESMO) have published guidelines for locoregional breast cancer that suggest in premenopausal women, clinicians should give adjuvant tamoxifen for 5 years in low-risk breast cancer, extend hormone therapy in high-risk patients, and consider adding ovarian function suppression (OFS) in patients with a higher risk of relapse.
I’d buy these FTSE 100 shares for their dividends
Globe Newswire Annual Financial Report 1 DECEMBER 2020 NORTHERN VENTURE TRUST PLC ANNUAL FINANCIAL REPORT FOR THE YEAR ENDED 30 SEPTEMBER 2020 Northern Venture Trust PLC is a Venture Capital Trust (VCT) whose investment adviser is Mercia Fund Management. The trust was one of the first VCTs launched on the London Stock Exchange in 1995.
Readability and content of online pet obesity information
Abstract December 1, 2020, Vol. 257, No. 11, Pages 1171-1180 Tom T.Chen, MSc1, Deep K.Khosa, BVMS, PhD1, Scott A.McEwen, DVM1, Sarah K.Abood, DVM, PhD2 and Jennifer E.McWhirter, PhD1 1Department of Population Medicine, Ontario Veterinary College, University of Guelph, Guelph, ON N1G 2W1, Canada. (Chen, Khosa, McEwen, McWhirter); 2Clinical Studies, Ontario Veterinary College, University of Guelph, Guelph, ON N1G 2W1, Canada. (Abood) Address correspondence to Dr. Khosa ().
Covid-19 vaccine: the 3 top stocks I’d buy right now
Coronavirus written newspaper close up shot to the text. The world has been anxiously waiting for a Covid-19 vaccine, so it’s no surprise that sentiment in stock markets turned quite optimistic in recent trading days. Last week, Pfizer announced that its experimental Covid-19 vaccine had proven effective, with more than 90% efficacy in preventing the disease. Moderna has also reported a vaccine that shows nearly 95% protection.
Cheap UK shares: is Vivo Energy worth buying right now?
Silhouette of an oil rig Energy stocks have suffered badly this year, largely due to the pandemic’s impact on global demand for oil consumption. One stock that fell hard since the Covid-19 pandemic emerged in March is Vivo Energy (LSE: VVO), a FTSE 250 company that has lost over 25% from the start of the year, and over 50% since 2018.
Stock market crash: I’d buy Spirax-Sarco Engineering shares for the new bull market
Globe Newswire Browser Isolation Software Market Forecast to 2027 - COVID-19 Impact and Global Analysis Dublin, Oct. 29, 2020 (GLOBE NEWSWIRE) -- The "Browser Isolation Software Market Forecast to 2027 - COVID-19 Impact and Global Analysis by Deployment (Cloud and On-Premise), Enterprise Size (Large Enterprises and SMEs), End-Use Industry (IT & Telecom, BFSI, Government, Manufacturing, and Others), and Geography" report has been added to ResearchAndMarkets.com's offering.
Why I think Aviva shares are a bargain right now
Compass pointing towards 'best price' The Aviva (LSE: AV) share price has been hit very hard by the coronavirus pandemic. After starting the year at 423.6p, the stock has fallen to levels not seen since 2009 and is currently down around 34% from the start of the year. As a matter of fact, regardless of the pandemic, Aviva has struggled in recent years and its share price has been stuck in a tight range since 2014. With that in mind, in the midst of every crisis lies a great investment opportunity.
2 UK cybersecurity shares I’d buy right now
Compass pointing towards 'best price' Cybersecurity shares have been somewhat resilient to the Covid-19 pandemic, and for a good reason. Despite the economic slowdown, the situation has pushed many governments, businesses and individuals to go online. As such, the adoption of new security measures against cyber crimes was inevitable. Two cybersecurity shares in the UK that seem to offer a good value for money right now are Avast (LSE: AVST) and BAE Systems (LSE: BA).
Here’s why I think any dip in the Taylor Wimpey share price offers a great long-term investment opportunity
Home key with house keyring with calculator. The Taylor Wimpey (LSE: TW) share price has been on a downward trend since the beginning of the year, largely due to the Covid-19 pandemic that has hit the stock markets in March. The giant British house building company suffered a £39.2m loss in the first half of the year as a result of the lockdown, and its shares dropped to the lowest levels since 2013.
Maykadeh Persian Cuisine
Excellent and very tasty Persian food , tried several dishes and all tasted superb , highly recommended , would visit again for sure ❤️ If you like baghali polo, only available on Sunday. They have joojeh kubideh (ground chicken breast) kabobs, as well as traditional joojeh kabob (chicken thigh) - prepared well, nice and tender. Yum! Kashke bademjun and rice were very good. Get tadig if they have it. If u get barg ask for it medium bc medium rare was a bit chewy.
B cells are associated with survival and immunotherapy response in sarcoma
Abstract Soft-tissue sarcomas represent a heterogeneous group of cancer, with more than 50 histological subtypes1,2. The clinical presentation of patients with different subtypes is often atypical, and responses to therapies such as immune checkpoint blockade vary widely3,4. To explain this clinical variability, here we study gene expression profiles in 608 tumours across subtypes of soft-tissue sarcoma.
Primary cardiac sarcomas: A multi‐national retrospective review
The full text of this article hosted at iucr.org is unavailable due to technical difficulties.
Next Frontiers in Systemic Therapy for Soft Tissue Sarcoma
Abstract and Introduction Abstract Soft tissue sarcoma (STS) is a heterogeneous disease with more than 50 subtypes. Once the disease reached locally advanced or metastatic status, the standard treatment remains to be chemotherapy. Current understanding of the underlying molecular and genomic mechanisms of different histology subtypes have led to encouraging development of new drugs in treating STS.
Next frontiers in systemic therapy for soft tissue sarcoma
Soft tissue sarcoma (STS) is a heterogeneous disease with more than 50 subtypes. Once the disease reached locally advanced or metastatic status, the standard treatment remains to be chemotherapy. Current understanding of the underlying molecular and genomic mechanisms of different histology subtypes have led to encouraging development of new drugs in treating STS. Besides molecular targeted therapy, immunotherapy have also shown promising advancement in solid tumor treatments.
Balancing act - Intellectual Property Magazine
In light of recent trends in intellectual property (IP) litigation that many have perceived as mostly unfavourable to patent owners, companies are scrambling to re-evaluate their strategies for patent portfolio management and IP acquisitions. In-house counsel are taking note of the plethora of disheartening conditions, many of which seem to caution against acquiring more IP assets.
The Week Ahead - Non-Farm Payrolls, RBA, Yellen and Draghi
As we enter the first week of October, a busy week is upon us with important economic events that might add volatility into markets. Here are the main economic events of the upcoming week: US Non-Farm Payrolls The crucial US non-farm payrolls will be released on Friday at 12:30 GMT.
North Korea - How Much of a Threat?
By the end of World War II, United States and Soviet Union took over the Korean country, ending a long Japanese rule of 35 years. During the cold war, both countries remained in a perpetual state of war, faced equal economic, political and social status. However, the fall of the Soviet Union has changed the … Continue reading North Korea – How Much of a Threat? By the end of World War II, United States and Soviet Union took over the Korean country, ending a long Japanese rule of 35 years.
The Week Ahead - Non Farm Payrolls, BoE and RBA Rate Decisions in Focus
As we enter the first week of August, a busy week is upon us with important economic events that might change the current trend. Financial markets have concluded the recent updates as the Federal Reserve switched its rate hike outlook and economic growth, and the dovish sentiment has affected US dollar and commodities.
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