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As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.Articles
SMD2 reads pseudouridines to regulate mRNA splicing and promote tumorigenesis
Keywords pseudouridine SMD2 SNRPD2 RNA modification splicing spliceosome mRNA tumorigenesis cancer Get full text access Log in, subscribe or purchase for full access. References 1. Wiener, D. ∙ Schwartz, S. The epitranscriptome beyond m6A Nat. Rev. Genet. 2021; 22:119-131 2. Rodell, R. ∙ Robalin, N. ∙ Martinez, N.M. Why U matters: detection and functions of pseudouridine modifications in mRNAs Trends Biochem. Sci. 2024; 49:12-27 3. Sun, H. ∙ Li, K. ∙ Liu, C. ...
Feedback loop promotes sucrose accumulation in cotyledons to facilitate sugar-ethylene signaling-mediated, etiolated-seedling greening
Highlights • Sucrose feedback signaling promotes its accumulation in cotyledons under darkness • Accumulated sucrose in cotyledons stimulates ethylene biosynthesis to enable greening Summary De-etiolation is indispensable for seedling survival and development. However, how sugars regulate de-etiolation and how sugars induce ethylene (ET) for seedlings to grow out of soil remain elusive. Here, we reveal how a sucrose (Suc) feedback loop promotes de-etiolation by inducing ET biosynthesis.
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