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Alex Chin on Muck Rack

Alex Chin

London
As seen in: Emerging Infectious Diseases, Nature, Wiley Online Library, ACS Publications, EurekAlert!, Inside Higher Ed, BioRxiv, Stem Cell Reports, Physical Review B, Canadian Medical Association Journal and
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Articles

Redirection of SARS-CoV-2 to phagocytes by intranasal sACE2-Fc as a universal decoy confers complete prophylactic protection

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By Jingyi Wang, Jiangchuan Li, Alex Chin
| eLife
eLife Assessment This manuscript presents a valuable antiviral approach using an engineered ACE2-Fc fusion protein that demonstrates broad-spectrum neutralization capacity against SARS-CoV-2 variants and achieves significant prophylactic protection in animal models through a novel Fc-mediated phagocytosis mechanism.
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Redirection of SARS-CoV-2 to Phagocytes by Intranasal sACE2-Fc as a Universal Decoy Confers Complete Prophylactic Protection

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By Jingyi Wang, Jiangchuan Li, Alex Chin
| BioRxiv
Abstract The rapid evolution of SARS-CoV-2 and other respiratory RNA viruses limits the success of current vaccines and antibody-based therapies. Engineered decoy receptors based on soluble angiotensin-converting enzyme 2 (sACE2) offer promising alternatives. Clinical-grade recombinant sACE2 inhibits SARS-CoV-2 replication in vitro but shows limited clinical success.
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6 Tips for Transferring Ph.D. Programs (opinion)

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By Alex Chin
| Inside Higher Ed Verified
Feel that your Ph.D. program is not the right fit? You are not alone. Completing a Ph.D. is a difficult experience, as research suggests that only about 57 percent of doctoral students in the United States and Canada complete their Ph.D. within 10 years. People leave for all sorts of reasons—but if your program is a poor fit, then you have options. One option that is rarely discussed is transferring.
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