Xiaolin Li
Baltimore
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Articles by Xiaolin Li
ROR1 upregulation after CD19-CAR T-cell relapse in mantle cell lymphoma identifies a targetable vulnerability for ROR1-directed bispecific modalities
To the Editor BTK inhibition and CD19-directed chimeric antigen receptor (CAR) T-cell therapy represent essential treatments for relapsed/refractory (R/R) mantle cell lymphoma (MCL) and have achieved impressive response rates [1]. Unfortunately, most patients eventually relapse due to therapy resistance, immune evasion, or waning efficacy [2]. Bispecific antibodies are being developed for relapsed disease, with multiple approved or clinically advanced candidates [3, 4].
A state-dependent dilatancy constitutive model and parametric analysis for dense sand–structure interfaces
Based on the above physical mechanism, this section establishes an incremental constitutive equation system for dense sand–structure interfaces. The model adopts an elastoplastic framework, uses the Mohr–Coulomb criterion to describe yielding under compression-shear conditions, introduces state-dependent dilatancy theory to characterize normal plastic deformation induced by interface shearing, and updates the normal stress through the CNS boundary condition.
Bouncing forward after failure: Entrepreneurial team resilience and venture growth in high-tech ventures
ABSTRACT Building upon the conservation of resource theory, we examined how entrepreneurial team resilience influences entrepreneurial venture growth through team task crafting within the context of entrepreneurial project failure in China. We also explored how hindrance stressors moderate this relationship. We collected three waves of data from 168 teams in high-tech entrepreneurial ventures in Yangtze River Delta region of China.
Differential proteomic analysis of lung tissues in rats with high-altitude pulmonary edema and screening of potential biomarkers
Abstract Introduction: High-altitude pulmonary edema (HAPE) is a severe complication of rapid exposure to high-altitude hypoxia, but its molecular mechanisms remain incompletely understood. This study aimed to characterize lung proteomic alterations in HAPE and identify candidate proteins associated with its pathophysiological processes. Methods: Male Wistar rats were randomly allocated to control and HAPE model groups (n = 20/group).
DP21901 Swap and Save: How a Button Shapes Lasting Online Grocery Shopping Behavior
English Français Deutsch Italiano 中文 More Español Ελληνικά 日本語 Português Türkçe A well-documented phenomenon in the literature is that consumers exhibit persistence in their choices. Using data from the mineral water category on a price comparison platform that delivers real-time prompts of cheaper alternatives through ``swap and save" buttons, this study examines whether and how these prompts influence persistent product choices in online grocery shopping.
A CT-enhanced multi-modal framework for predicting early conversion to arthroplasty in patients with intracapsular hip fractures
Abstract Intracapsular hip fractures are a leading cause of disability in young and middle-aged adults and are associated with high failure and reoperation rates. Accurate preoperative prediction of conversion to arthroplasty is crucial for quantifying individual prognosis and potentially informing individualized, clinician-led treatment decisions. Yet models built solely on structured electronic health records (EHRs) are insufficient.
The impact of unmanned aerial vehicle applications on agricultural carbon emission
Abstract Agricultural carbon emissions constitute a major contributor to global warming, yet the specific impact of drone technology on such emissions remains unclear. This study attempts to fill this research gap. Taking agricultural drones as the key carrier, this paper constructs a Spatial Autoregressive Model by means of spatial econometric methods based on the panel data of 31 Chinese provinces spanning from 2014 to 2023.
Dissimilar Maraging Stainless Steel With Superior Strength Matching Produced by Laser Repair and Tailored Heat Treatment
Conflicts of Interest The authors declare no conflicts of interest. Data Availability Statement Data will be made available on request. Supporting Information Filename Description srin70618-sup-0001-SuppData-S1.pdf357.7 KB Supplementary Material References 1, , , et al., “Ultrafine-Grained Dual-Phase Maraging Steel with High Strength and Excellent Cryogenic Toughness,” Acta Materialia 211 (2021): 116878.
Hemodynamic variations in resting-state cerebral functional networks between Tibetan and Han male athletes assessed by fNIRS
Abstract This study seeks to compare systemic variations in functional connectivity within core motor brain regions at rest between young male soccer players from the indigenous Tibetan population of the Tibetan Plateau and their counterparts from the Han population of the plains, to elucidate the intrinsic relationship between specific ethnic backgrounds and central nervous system hemodynamic phenotypes.
Lactate-Informed Exercise Prescription in Mild Cognitive Impairment and Alzheimer’s Disease: A Translational Framework for Preserving Cognition, Mobility, and Independence
Back to Journals » Clinical Interventions in Aging » Volume 21 Authors Li X Received 16 July 2026 Accepted for publication 6 October 2026 Published 12 October 2026 Volume 2026:21 641221 DOI https://doi.org/10.2147/CIA.S641221 Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 2 Editor who approved publication: Prof.
Metagenomic next-generation sequencing in tuberculous periprosthetic joint infection: pathogen-detection yield and clinical characteristics compared with common bacterial PJI
Abstract Objective: To compare the pathogen-detection yield of metagenomic next-generation sequencing (mNGS) and conventional culture in tuberculous periprosthetic joint infection (TB-PJI) and common bacterial PJI (CB-PJI), and to characterize clinical differences and exploratory associations with TB-PJI.
Reversible and irreversible BTK inhibition promotes stem-like functional multipotency, persistence, and antitumor efficacy of CD19-directed CAR T cells in mantle cell lymphoma
To the Editor, Mantle cell lymphoma (MCL) is a distinct subtype of B-cell lymphoma characterized by overexpression of cyclin D1 [1]. BTK inhibition and CD19-directed chimeric antigen receptor (CAR) T-cell therapy have achieved substantial efficacy. However, MCL frequently relapses, due to therapy resistance, immune escape, and failure of adoptive cell therapies [2].
Influence of Nano/Ultrafine-To-Micron Grain Ratio on the Strength-Ductility Synergy in a Heterostructured Fe–17Cr–6Ni Steel
Conflicts of Interest The authors declare no conflicts of interest. Data Availability Statement The data that support the findings of this study are available from the corresponding author upon reasonable request. Supporting Information Filename Description srin70590-sup-0001-SuppData-S1.pdf659 KB Supplementary Material References 1 and , “The Influence of Nanocrystalline Structure and Processing Route on Corrosion of Stainless Steel: A Review,” Corrosion Science 92 (2015): 1–15.
Polymer-Based Multiparameter Sensing Integrated Photonic Chip for Health Monitoring
1 Introduction Health monitoring involves the continuous tracking of various health-related aspects. This process involves measuring parameters such as body temperature, pulse, electrocardiogram (ECG) parameters, and blood glucose [1-4]. Health monitoring involves real-time online monitoring of the health conditions of users and helps doctors detect diseases early, which is crucial for maintaining good health.
The Mechanism and Application of Traditional Chinese Medicine Nano-Formulations in the Treatment of Renal Fibrosis
Back to Journals » International Journal of Nanomedicine » Volume 21 Authors Zhang L, Liu T, Li X, Chen S, Wang S, Ma H, Liu M Received 20 April 2026 Accepted for publication 8 July 2026 Published 24 July 2026 Volume 2026:21 616604 DOI https://doi.org/10.2147/IJN.S616604 Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 3 Editor who approved publication: Professor Eng San Thian Lu Zhang,1,2,* Tianlong Liu,3,* Xiaolin Li,3 Sirui Chen,1,2...
Superconvergent Meshless Collocation Method for Nonlinear Neutral Delay‐Reaction‐Diffusion Equation
In this article, a novel meshless superconvergent finite point method (SFPM) is developed for a class of nonlinear neutral delay-reaction-diffusion (NDRD) equation. We begin with a second-order scheme to obtain the temporal semi-discretization of the nonlinear NDRD equation.
USP30-mediated Deubiquitination of Hexokinase 2 controls the metabolic fate of glucose and tumor progression - Cell Death & Disease
Abstract The mitochondria-localized deubiquitinase USP30 regulates mitophagy and mitochondrial homeostasis, playing a significant role in the progression of neurodegenerative diseases. However, its role in cancer remains poorly understood. Through metabolism-related gene set enrichment analysis, we identified USP30 as a key modulator of glucose metabolism in cancer cells.
Multi-Layer Separation Tank Integrating Flocculation and Centrifugation for Treating Sediment-Laden Water with Complex Particles
Submitted: 09 February 2026 You are already at the latest version To address the feasible issues in water treatment facilities such as low particle removal and overuse of chemical in flocculation-sedimentation treatment of complex sediment-laden particles in snowmelt and high-intensity rainfall water, this research presents a new multi-layered separation tank.
In Situ Fragmentation of Bimetallic Sulfides to Construct Ultrafine MoS2/SnS2 Heterostructures Embedded in Carbon Frameworks for Enhanced Sodium Storage
Abstract Click to copy section linkSection link copied! Metal sulfide heterostructures have attractive Na+ storage performance because of the subtle synergy; however, current synthesis of heterostructured metal sulfides typically is based on cohydrothermal reactions or mechanical mixing followed by high-temperature sulfidation, often yielding heterostructures with large particle sizes and nonuniform interfaces.
Tailoring Strength‐Toughness Synergy in 18Ni (200) Maraging Steel by Adjusting Aging Temperature and Time
Conflict of Interest The authors declare no conflict of interest. Data Availability Statement The data that support the findings of this study are available from the corresponding author upon reasonable request. References 1, , , , , , , , J. Mater. Res. Technol. 2021, 10, 471. 2, , , , Adv. Eng. Mater. 2019, 21, 1801116. 3, , , , Metall. Mater. Trans. A 2019, 50, 3502. 4, , , , , , , Mater. Sci. Eng.: A 2019, 758, 192. 5, , , , , , Steel Res. Int. 2025, 2500328. 6, , , , , , , J. Mater. Sci. 2021, 56, 11469.
Analysis of changes in farmers’ household livelihood: a case study of Yao ethnic village in Guangxi
ABSTRACT Supported by China's targeted poverty alleviation policies and Rural Revitalization Strategy, tourism has rapidly developed into the main driver transforming residents’ household model in Guangxi's Yao village. These policies empower tourism, which in turn diversifies income, encourages labour return, and reshapes farmers’ household livelihood.
Primary‐Stage Colon Cancer Impairs Muscle Energy Metabolism by Suppressing Mitochondrial Complex I Activity
1 Introduction Cancer cachexia is a complex condition characterized by significant muscle loss [1, 2], affecting up to 80% [3] of patients with advanced-stage cancer, particularly those with gastrointestinal (GI) and lung cancers [4, 5]. Among cancers of the GI tract, colon cancer (CC) is the most prevalent [5], with approximately 30% of patients exhibiting cachexia at diagnosis [4, 5].
Quantum Wave Probability Derive Thermodynamic Distribution
Submitted: 07 November 2025 You are already at the latest version Subscription Notify me about updates to this article or when a peer-reviewed version is published. This version is not peer-reviewed. Submitted: 07 November 2025 You are already at the latest version Using the concept of quantum wave probability, combined with the identity principle, we can derive the Boltzmann distribution, Fermi distribution, and Bose distribution. Different distributions correspond to different conditions.
An Unusual Chemoselective Cycloaddition of Nonstabilized Azomethine Ylide: Synthesis of Oxazolidine Derivatives
An unusual [3 + 2] cycloaddition involving nonstabilized azomethine ylides and unsaturated carbonyl compounds is reported, wherein the reaction exclusively occurs at the carbonyl group rather than the conjugated double bond. This annulation strategy enables the efficient synthesis of a diverse range of substituted oxazolidine frameworks with excellent yields (up to 96%) under mild reaction conditions.
EEG‐Based Deep Learning Model for Hyper‐Acute Large Vessel Occlusion Stroke Detection in Mice
1 Introduction Ischemic stroke is one of the leading causes of disability and death worldwide, particularly when it involves large vessel occlusion (LVO), where the severity is significantly higher [1, 2]. LVO often leads to extensive brain tissue damage, clinically manifesting as acute neurological deficits, frequently accompanied by severe impairments in motor, cognitive, and sensory functions [2, 3].
Virtual and human streamers: the effect of interaction with product type on consumer purchase intention
Grounded in SOR theory and Persuasion theory, this study examines the interactive effects of streamer type (real vs. virtual) and product type (search vs. experience) on consumer purchase intention in a live marketing context. Through a combination of scenario experiments and questionnaires, this study examined the effects of streamer type and product type on consumers’ purchase intention in Study 1.
RinRK1's extracellular domain acts as a host‐specific gatekeeper for rhizobial infection in Medicago truncatula
CONFLICT OF INTEREST The authors have not declared a conflict of interest. Supporting Information Filename Description tpj70340-sup-0001-FigureS1.docxWord 2007 document , 24.1 MB Figure S1. Phylogenetic analysis of RinRK1. Figure S2. Expression patterns and regulatory elements of RinRK1 in M. truncatula A17 and R108. Figure S3. Characterization of Mtrinrk1, Mtlyk2bis and Mtnfp mutants. Figure S4. Infection and nodule phenotype of Mtrinrk1 mutants inoculated with different rhizobia. Figure S5.
An Overview of Ophthalmic Complications Associated With Emerging/Re‐Emerging Viruses: Focus on ZIKV, DENV, SARS‐CoV‐2, and MPXV
Conflicts of Interest The authors declare no conflicts of interest. References 1 and , “Emerging Infectious Diseases: Threats to Human Health and Global Stability,” PLoS Pathogens 9, no. 7 (2013): e1003467, https://doi.org/10.1371/journal.ppat.1003467. 2, , , , , and , “Bilateral Posterior Uveitis Associated With Zika Virus Infection,” Lancet 389, no. 10064 (2017): 125–126, https://doi.org/10.1016/s0140-6736(16)32518-1.
Conformally coated scaffold design using water-tolerant Pr1.8Ba0.2NiO4.1 for protonic ceramic electrochemical cells with 5,000-h electrolysis stability | Nature Energy
Abstract Protonic ceramic electrochemical cells (PCECs) have potential as long-duration energy storage systems. However, their operational stability is limited under industrially relevant conditions due to the intrinsic chemical instability of doped barium cerate-based electrolytes and oxygen electrodes against H2O, as well as the poor electrode–electrolyte interfacial contact. Here we present a conformally coated scaffold (CCS) design to comprehensively address these issues.
Conductive Lanthanum Ion‐Implanted Zeolite‐Supported Amorphous Metal-Organic Frameworks for Oxygen Reduction Reaction
Conflict of Interest The authors declare no conflict of interest. Supporting Information Filename Description adfm202510605-sup-0001-SuppMat.docx2.4 MB Supporting Information References 1, , , Angew. Chem., Int. Ed. 2022, 61, 202112835. 2, , , , , , , , Nat. Rev. Earth Environ. 2022, 3, 141. 3, , , , , , , , Adv. Mater. 2022, 34, 2201547. 4, , , , Chem. Soc. Rev. 2023, 52, 6139. 5, , , , , , , , , , , J. Am. Chem. Soc. 2023, 145, 17485. 6, , , , , , Renewables 2023, 1, 90.
Full article: The relationship between inflammatory factors and major adverse cardiovascular events in atherosclerosis coronary artery ectasia: a prospective, cohort study
Abstract Background To investigate the relationship among high sensitive C reactive protein (hs-CRP), interleukin (IL)-6, tumour necrosis factor (TNF)-α, matrix metalloproteinase (MMP)-9, growth differentiation factor (GDF)-15, corrected thrombolysis in myocardial infarction (TIMI) frame count and major adverse cardiovascular events (MACEs) in atherosclerosis coronary artery ectasia (CAE). Materials and Methods One hundred and sixty-five CAE patients were included.
[2505.12756] A note on global in-time behavior for the semilinear nonlocal heat exchanger system
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A duodenal spindle cell lipoma removed by endoscopic resection
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A Piezoelectric and Suture‐Free Cardiac Patch Assembled by all FDA‐approved Materials Achieves a Minimally Invasive Gene Therapy
Conflict of Interest The authors declare no conflict of interest. Supporting Information Filename Description adfm202425399-sup-0001-SuppMat.docx14.5 MB Supporting Information adfm202425399-sup-0002-MovieS1.MOV14.8 MB Supplemental Movie 1 adfm202425399-sup-0003-MovieS2.mov11.8 MB Supplemental Movie 2 References 1, , , , Signal. Transduct. Tar. 2021, 6, 122. 2, , , , , , Chem. Soc. Rev. 2012, 41, 2323. 3, , , Environ. Chem. Lett. 2022, 20, 445. 4, , , , , , , , , Circulation 2024, 149, 2002.
Electric field promoted odontogenic differentiation of stem cells from apical papilla by remodelling cytoskeleton
INTRODUCTION Pulp regeneration is a promising and difficult field of research in the treatment of endodontic diseases in recent years (Sui et al., 2019). Through the combination of growth factors and scaffold materials, stem cells are induced to differentiate into dentine-pulp complex (Yasui et al., 2017), repairing damaged tissues and restoring physiological functions.
Molecular Mechanisms of Neutrophil Extracellular Traps in Promoting Gastric Cancer Epithelial-Mesenchymal Transition Through SERPINE‐1 Expression
1 Introduction Gastric cancer remains one of the leading causes of cancer-related deaths worldwide, with its aggressive nature and propensity for metastasis contributing significantly to poor patient outcomes [1]. The epithelial–mesenchymal transition (EMT) is a critical process in cancer progression, enabling epithelial cells to acquire mesenchymal traits, thus facilitating invasion and metastasis [2].
Effects of fermented wheat germ on the placenta of high-fat diet-induced obese maternal rats: morphology, metabolism, and nutrient transport
Effects of fermented wheat germ on the placenta of high-fat diet-induced obese maternal rats: morphology, metabolism, and nutrient transport† Maternal obesity impairs placental function, affecting fetal growth and long-term health. Although fermented wheat germ (FWG) provides health benefits, its impact on maternal obesity-related metabolic disorders and placental function remains unclear.
A comprehensive review of recombinant technology in the food industry: Exploring expression systems, application, and future challenges
CONFLICT OF INTEREST STATEMENT The authors declare that they have no conflicts of interest or personal relationships that could have appeared to influence the work reported in this article. REFERENCES , & (2018). Recent advances in chromatographic purification of plasmid DNA for gene therapy and DNA vaccines: A review. Analytica Chimica Acta, 1025, 41–57. https://doi.org/10.1016/j.aca.2018.04.001 , , , , & (2023).
High Catalytic Performance of Bimetallic Sites Catalyst MOF@MT‐COF‐Cu for Benzimidazole and Benzothiazole Derivatives
Conflicts of Interest The authors declare no conflicts of interest. Supporting Information Filename Description aoc70035-sup-0001-Suppl-material.docxWord 2007 document , 2.4 MB FIGURE S1. MS spectrum of the compound 3aa. FIGURE S2. MS spectrum of the compound 3ab. FIGURE S3. MS spectrum of the compound 3 ac. FIGURE S4. MS spectrum of the compound 3ad. FIGURE S5. MS spectrum of the compound 3ae. FIGURE S6. MS spectrum of the compound 3af. FIGURE S7. MS spectrum of the compound 3ag. FIGURE S8.
Salt-in-presalt electrolyte solutions for high-potential non-aqueous sodium metal batteries - Nature Nanotechnology
Abstract Room-temperature non-aqueous sodium metal batteries are viable candidates for cost-effective and safe electrochemical energy storage. However, they show low specific energy and poor cycle life as the use of conventional organic-based non-aqueous electrolyte solutions enables the formation of interphases that cannot prevent degradations at the positive and negative electrodes.
A Tribo/Piezoelectric Nanogenerator Based on Bio‐MOFs for Energy Harvesting and Antibacterial Wearable Device
Conflict of Interest The authors declare no conflict of interest.
Hysteroscopy combined with laparoscopy in the diagnosis and treatment of omentum majus incarceration secondary to uterine perforation: A case report and literature review - Li - 2025 - Journal of Obstetrics and Gynaecology Research - Wiley Online Library
INTRODUCTION Maternal mortality remains a significant global health concern, often exacerbated by complications from induced abortion.1, 2 Approximately 14% of maternal deaths are attributed to complications related to induced abortions, including hemorrhage, sepsis, and uterine perforation.1, 3 Developing countries bear the brunt of these risks, with unsafe abortions contributing substantially to mortality rates.4 In this report, we describe an uncommon case of asymptomatic incarceration of...
Value of intraoperative post-conisation human papillomavirus testing in predicting residual or recurrence after treatment with a loop electrosurgical excision procedure in women with HR-HPV positive and cervical high-grade squamous intraepithelial lesion
To evaluate the feasibility of intraoperative human papillomavirus (IOP-HPV) testing for the prediction of postoperative treatment failure in patients with high-grade squamous intraepithelial lesion (HSIL) undergoing loop electrosurgical excisional procedure (LEEP). A total of 114 women diagnosed with HSIL by biopsy and/or endocervical curettage who underwent LEEP were included in a prospective cohort study. IOP-HPV testing was performed immediately after the procedure.
Letter to the Editor ‘Analysis of Factors Related to Physical Activity Levels Among Lung Cancer Survivors Who Underwent Nonsurgical Treatment: A Cross‐Sectional Study’ - Liu - 2025 - Journal of Clinical Nursing - Wiley Online Library
No abstract is available for this article. References , , and . 2024. “Determinants and Factors of Physical Activity After Oncology Treatments (DEFACTO) in Metropolitan France: Protocol of a Mixed Methods Study and Intervention.” JMIR Research Protocols 13: e52274. https://doi.org/10.2196/52274. , , , et al. 2023. “Physical Activity, Obesity, and Quality of Life Among Rural Australian Cancer Survivors: A Cross-Sectional Study.” Supportive Care in Cancer 31, no. 4: 222.
Engineering Ion Affinity of Zr-MOF Hybrid PDMS Membranes for the Selective Separation of Na+/Ca2+
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Microencapsulation Efficiency of Carboxymethylcellulose, Gelatin, Maltodextrin, and Acacia for Aroma Preservation in Jasmine Instant Tea
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
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