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Xiaoying Ye on Muck Rack

Xiaoying Ye

As seen in: Nature, Wiley Online Library, Respiratory Research, Cell Press, Cell Reports Medicine, Dove Medical Press, Dialnet - Universidad de La Rioja, Molecular Cancer Research
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Articles

Metabolically reprogrammed blastoids from totipotent-like stem cells exhibit enhanced tissue-specific organ-like development and placental formation

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By Yongqin Yu, Guoxing Yin, Xiaoying Ye, Guofeng Feng, Jie Li, Chang Liu, Jiangtao Lu, Kairang Jin, Zhiming Wang, Suming Xu, Xueqing Wu, Lin Liu
| Nature Verified
Abstract While blastoids derived from pluripotent stem cells recapitulate pre- and early post-implantation embryogenesis, their long-term post-implantation development remains constrained. We define Snαnv, a chemical cocktail that promotes oxidative-phosphorylation-driven metabolic reprogramming, to efficiently generate ESC-blastoids with proper trophectoderm (TE)/inner cell mass (ICM) from conventional mouse ESCs at an efficiency of approximately 70%.
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A Novel KCNQ2 Gain‐of‐Function Variant I134N Causes Severe Developmental and Epileptic Encephalopathy

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By Xiaoying Ye, Zhaobing Gao, Fengmei Zeng
| Wiley Online Library Verified
Disclosure All authors agreed to publish this article. Conflicts of Interest The authors declare no conflicts of interest. Data Availability Statement The data that support the findings of this study are available on request from the corresponding author. The data are not publicly available due to privacy or ethical restrictions. References , , , et al. 2024.
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Ribosome dysregulation and intervention in age-related infertility

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By Jie Li, Honghong Wang, Pengfei Zhu, Haixia Chen, Haiyang Zuo, Chang Liu, Linlin Liu, Xiaoying Ye, Yiwei Wu, Qinli Liu, Tao Yang, David L. Keefe, Xiaohong Bai, Wei Shang, Xueqing Wu, Lin Liu, Guofeng Feng
| Cell Reports Medicine Verified
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