Xue-Ying Li
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Tensor decomposition reveals discrete cortical reorganization under graded propofol anesthesia
Abstract Background: Although propofol-induced anesthesia is known to suppress consciousness by promoting low-frequency frontal oscillations through thalamocortical circuits, a comprehensive understanding of its whole-brain coupling feature set remains elusive. Specifically, the global reorganization of nonlinear cross-frequency coupling remains poorly characterized due to analytical limitations.
Aberrant dynamic functional architecture in major depressive disorder: Vertex-Wise large-sample fMRI analyses reveal network-specific alterations and symptom associations | Translational Psychiatry
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Abstract Major depressive disorder (MDD) imposes significant global health burdens, yet its underlying neural mechanisms remain elusive. Traditional static functional metrics inadequately capture the brain’s dynamic nature, motivating the exploration of dynamic functional metrics to understand both the temporal and spatial reconfigurations of brain networks in MDD.
By Xue-Ying Li, Bin Lu, Xiao Chen, Zi-Han Wang, Yu-Wei Wang, Yi-Fan Liao, Han-Lin Wang, Qing-Lin Gao, Yan-Rong Chen, Xin-Yu Wang, Hai-Long Liu, Tao Chen, Xi-Long Cui, Qi-Yong Gong, Wen-Bin Guo, Qian Huang, Feng-Nan Jia, Li Kuang, Feng LI, Hui-Xian Li, Tao Li, Xiao-yun Liu, Yan-Song Liu, Zhe-Ning Liu, Jiang Qiu, Tian-Mei Si, Chuan-Yue Wang, Hua-ning Wang, Xiang Wang, Ying Wang, Xin-Ran Wu, Yan-Kun Wu, Chun-Ming Xie, Peng Xie, Xiu-Feng Xu, Jian Yang, Hua Yu, Yong-Qiang Yu, Yong-Gui Yuan, Ai-Xia Zhang, Ke-rang Zhang, Wei Zhang, Jing-Ping Zhao, Jia-Jia Zhu, Xi-Nian Zuo, Chao-Gan Yan, Zheng-Jia-Yi Hu, Chen-Nan Wu, Si-Cheng Chen, Ze-Di Lin, Li-Ping Cao, Guan-Mao Chen, Jian-Shan Chen, Tao-Lin Chen, Yu-Qi Cheng, Zhao-Song Chu, Can-Can He, Xin-Lei Ji, Bao-Juan Li, Yi-Cheng Long, Jian-Ping Lu, Xiao-Xiao Shan, Peng-Feng Sun, Guang-Rong Xie, Zhen-Peng Xue, Min-Lan Yuan, Xiao-Ping Wu
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Nature
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Subgenual Anterior Cingulate Cortex Functional Connectivity Abnormalities in Depression: Insights from Brain Imaging Big Data and Precision-Guided Personalized Intervention via Transcranial Magnetic Stimulation
Abstract Background: The subgenual anterior cingulate cortex (sgACC) plays a central role in the pathophysiology of major depressive disorder (MDD), and its functional interactive profile with the left dorsal lateral prefrontal cortex (DLPFC) is associated with transcranial magnetic stimulation (TMS) treatment outcomes. Nevertheless, previous research on sgACC functional connectivity (FC) in MDD has yielded inconsistent results, partly due to small sample sizes and limited statistical power.
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