Yael David

Keywords efferocytosis tissue-resident macrophages microplastics polystyrene phagocytosis methylglyoxal immunometabolism Introduction Macrophages, the body’s immune sentinels, are exposed to a diverse range of contents, and because of this, have evolved a repertoire of processes for differentiating between non-self and self, damaged and healthy, and inflamed and homeostatic.1,2,3,4,5 One such process, efferocytosis, or the phagocytic removal of apoptotic cells (ACs), is essential for tissue...

1EpiCypher Inc, Durham, NC 27709, USA 2Institut Curie, PSL Research University, CNRS, Sorbonne Université, Nuclear Dynamics Unit, Equipe Labellisée Ligue Contre le Cancer, 75005 Paris, France 3University of North Carolina at Wilmington, Wilmington, NC 28403, USA 4Department of Biochemistry and Molecular Pharmacology, New York University Grossman School of Medicine, New York, NY 10016, USA 5Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 1L7, Canada 6Structural...

1Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA 2Department of Pharmacology, Weill Cornell Medicine, New York, NY, USA 3Tri-Institutional PhD Program in Chemical Biology, New York, NY, USA 4Department of Epigenetics, Van Andel Institute, Grand Rapids, MI, USA 5Department of Epidemiology & Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA 6Department of Neuroscience, Icahn School of Medicine, Mount Sinai, New York, NY, USA 7Department...