Yaping Sun
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Articles by Yaping Sun
Processing-induced assembly pathways of rice glutelin: from nanostructure formation to functional performance
INTRODUCTION With the increasing global population and growing concerns about the negative environmental impacts caused by animal protein production, there has been a shift from animal-derived to plant-derived protein sources.1, 2 This shift is driven by the demand for sustainable, health-oriented, and ethically sound alternatives.
Research on bandgap optimization of aperiodic magnetorheological elastomer metamaterial sandwich beam based on genetic algorithm
Abstract In recent years, local resonant metamaterial structures with tunable bandgap characteristics have attracted increasing interest and attention from researchers. In order to achieve the widest local resonant bandgap, an offline-online combined optimization method for the bandgap of the aperiodic magnetorheological elastomer (MRE) metamaterial sandwich beam (AMREMSB) based on a genetic algorithm and the spectral element method was proposed in this study.
Archipelago architecture and evolution of paclitaxel biosynthesis revealed by the Pseudotaxus chienii haplotype-resolved genome
Abstract Pseudotaxus chienii, the only species in the genus Pseudotaxus, is closely related to Taxus genus. Whether P. chienii can produce paclitaxel has long remained controversial. Here, we present a chromosome-level, haplotype-resolved genome of P. chienii, with each haplotype ( ~ 15.4 Gb) exhibiting high continuity and completeness.
Parameter calibration method for car-following models under snowy weather conditions: Integrating an informer time series encoder and physics-informed neural networks
Loading metrics Open Access Peer-reviewed Research Article Citation: Sun Y, Li W, Yang M, Zhang X (2026) Parameter calibration method for car-following models under snowy weather conditions: Integrating an informer time series encoder and physics-informed neural networks. PLoS One 21(6): e0350550.
Author Correction: Mitochondrial complex II in intestinal epithelial cells regulates T cell-mediated immunopathology
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Correction to: Nature Immunology https://doi.org/10.1038/s41590-021-01048-3, published online 22 October 2021. In the version of this article initially published, in the “Kidney” column of Extended Data Fig. 2a, the “Syn” microscopy image was a duplicate of the “Naive” image above it, due to an error in figure preparation. The correct image of the kidney from syngeneic mice has now been added to the HTML and PDF versions of Extended Data Fig. 2a.
By Hideaki Fujiwara, Keisuke Seike, Michael Brooks, Anna Mathew, Ilya Kovalenko, Anupama Pal, Ho-Joon Lee, Daniel Peltier, Stephanie Kim, Chen Liu, Katherine I. Oravecz-Wilson, Lu Li, Yaping Sun, Jaeman Byun, Yoshinobu Maeda, Max S Wicha, Thomas Saunders, Alnawaz Rehemtulla, Costas A. Lyssiotis, Subramaniam Pennathur
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Nature
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MHC class I on target cells regulates CD4 + T cell-mediated immunity
Abstract Major histocompatibility complex (MHC) class I and class II molecules present antigens to CD8+ and CD4+ T cells respectively. Here we uncover a previously unrecognized role for MHC class I in modulating CD4+ T cell-mediated immunity. In allogeneic graft-versus-host disease and tumor models, we demonstrate that the absence of MHC class I on target cells significantly increases their susceptibility to CD4+ T cell cytotoxicity.
Formation mechanisms, fabrication strategies, and applications of casein–polyphenol complexes
Sun, Y. and Zhao, Z. (2026), Formation mechanisms, fabrication strategies, and applications of casein–polyphenol complexes. J Sci Food Agric. https://doi.org/10.1002/jsfa.70584 CONFLICT OF INTEREST The authors declare that they have no conflict of interest. DATA AVAILABILITY STATEMENT The data that support the findings of this study are available from the corresponding author upon reasonable request.
Correlation between the neutrophil‐to‐lymphocyte ratio and enlarged perivascular spaces in type 2 diabetes mellitus
INTRODUCTION As the chronic metabolic disease with the most rapidly increasing prevalence worldwide, type 2 diabetes mellitus induces multi-system complications through chronic hyperglycemia. Among these complications, cognitive impairment and stroke caused by cerebral small vessel disease (CSVD) are leading causes of disability and mortality1, 2.
Macroporous scaffolds based on biomass polymers and their applications in wound healing
Article Navigation > Journal of Bioresources and Bioproducts > 2025 > 10(1): 14-31 Daqian Gao, William D. Shipman, Yaping Sun, Joshua Zev Glahn, Leleda Beraki, Henry C. Hsia. Macroporous scaffolds based on biomass polymers and their applications in wound healing[J]. Journal of Bioresources and Bioproducts, 2025, 10(1): 14-31. doi: 10.1016/j.jobab.2024.12.001 Citation: Daqian Gao, William D. Shipman, Yaping Sun, Joshua Zev Glahn, Leleda Beraki, Henry C. Hsia.
An Injectable Alginate Hydrogel Modified by Collagen and Fibronectin for Better Cellular Environment
Development of Anti-HIV Therapeutics: From Conventional Drug Discovery to Cutting-Edge Technology
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Development of Anti-HIV Therapeutics: From Conventional Drug Discovery to Cutting-Edge Technology
Preprint Review Version 1 This version is not peer-reviewed Version 1 : Received: 22 January 2024 / Approved: 23 January 2024 / Online: 23 January 2024 (07:54:00 CET) Sun, Y.; Wang, L. Development of Anti-HIV Therapeutics: From Conventional Drug Discovery to Cutting-Edge Technology. Preprints 2024, 2024011662. https://doi.org/10.20944/preprints202401.1662.v1 Sun, Y.; Wang, L. Development of Anti-HIV Therapeutics: From Conventional Drug Discovery to Cutting-Edge Technology. Preprints 2024, 2024011662.
Parents’ experiences and need for social support after pregnancy termination for fetal anomaly: a qualitative study in China
Subtheme: Query and verification of fetal abnormalities Without psychological preparation, parents initially showed strong shock and denial in the face of the diagnosis of fetal abnormalities. They often took the initiative to think about the causes of fetal abnormalities and repeatedly sought confirmation. I broke down and sat in a hospital chair for two hours, not believing it (participant 13A).
Interleukin 4 gene polymorphisms and the risk of tuberculosis: A meta-analysis
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ATG5-Dependent Autophagy Uncouples T-cell Proliferative and Effector Functions and Separates Graft-versus-Host Disease from Graft-versus-Leukemia
Translational Science Katherine Oravecz-Wilson, Corinne Rossi, Cynthia Zajac, Yaping Sun, Lu Li, Thomas Decoville, Hideaki Fujiwara, Stephanie Kim, Daniel Peltier and Pavan Reddy DOI: 10.1158/0008-5472.CAN-20-1346 Published February 2021 This article requires a subscription to view the full text. You may purchase access to this article or login to access your subscription using the links below.
ATG5-dependent autophagy uncouples T cell proliferative and effector functions and separates graft-versus-host disease from graft-versus-leukemia
Research Article Katherine Oravecz-Wilson, Corinne Rossi, Cynthia Zajac, Yaping Sun, Lu Li, Thomas Decoville, Hideaki Fujiwara, Stephanie Kim, Daniel Peltier and Pavan Reddy DOI: 10.1158/0008-5472.CAN-20-1346 Abstract Autophagy is a vital cellular process whose role in T immune cells is poorly understood, specifically, in its regulation of allo-immunity. Stimulation of wild type T cells in vitro and in vivo with allo-antigens enhances autophagy.
Expression of Concern: Cardiac overexpression of myotrophin triggers myocardial hypertrophy and heart failure in transgenic mice.
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MicroRNA-142 Is Critical for the Homeostasis and Function of Type 1 Innate Lymphoid Cells
Highlights • miR-142 is induced by IL-15 and is required for type 1 ILC development and homeostasis • miR-142 targets Socs1 thereby promotes IL-15 receptor signaling in type 1 ILCs • αV integrin, a miR142-3p target, promotes IL-15-independent survival in type 1 ILCs • miR-142 is critical for cytokine production and NK-cell-mediated viral control Summary Natural killer (NK) cells are cytotoxic type 1 innate lymphoid cells (ILCs) that defend against viruses and mediate anti-tumor responses, yet...
Major Histocompatibility Complex Class I (FLA-E*01801) Molecular Structure in Domestic Cats Demonstrates Species-Specific Characteristics in Presenting Viral Antigen Peptides
Feline immunodeficiency virus (FIV) infection in domestic cats is the smallest usable natural model for lentiviral infection studies. FLA-E*01801 was applied to FIV AIDS vaccine research. We determined the crystal structure of FLA-E*01801 complexed with a peptide derived from FIV (gag positions 40 to 48; RMANVSTGR [RMA9]). The A pocket of the FLA-E*01801 complex plays a valuable restrictive role in peptide binding.
A Sec22b knockout mouse offers novel insights into the molecular mechanisms of crosspresentation
Crosspresentation critically contributes to the adaptive immune response to tumors and viral infection by presenting extracellular antigen on MHC I to activate CD8 T cells. However, its molecular regulation is poorly understood. Using in vitro shRNA-mediated knockdown (KD) methods, another group had shown that Sec22b, an ER-SNARE, specifically regulates crosspresentation. Thus, we tested the hypothesis that Sec22b would mediate crosspresentation in vivo.
microRNA-142 is critical for peripheral NK cell homeostasis and function.
MicroRNAs (miRNA) are small, non-coding RNAs that post-transcriptionally regulate the translation of their targeted mRNAs. Next-generation small RNA sequencing has identified a number of mature miRNAs that are highly expressed in murine NK cells, including miR-142. We hypothesized that miR-142-5p/3p regulated NK cell development, survival, or functionality, and investigated this concept by examining the NK cell compartment in miR-142−/− mice.
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