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Yi-Ying Wu

As seen in: Nature, Wiley Online Library, MDPI, JAMA Oncology, Journal of Biomedical Science, BioRxiv, Canadian Journal of Infectious Diseases & Medical Microbiology
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Articles

Lidocaine Modulates Cytokine Production and Reprograms the Tumor Immune Microenvironment to Enhance Anti-Tumor Immune Responses in Gastric Cancer

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By Yi-Ying Wu, Ming-Shan Chen, I-Chun Chen, Feng-Hsu Wu
| MDPI
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
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Lidocaine Enhances Anti-Tumor Immune Responses by Reprogramming Tumor-Infiltrating Immune Cells in Gastric Cancer

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By Yi-Ying Wu, Ming-Shan Chen, I-Chun Chen, Feng-Hsu Wu
| preprints.org
Submitted: 24 February 2025 You are already at the latest version Lidocaine, a local anesthetic, has been shown to modulate immune responses. This study examines its effects on cytokine production in peripheral blood mononuclear cells (PBMCs) from healthy donors and tumor-infiltrating immune cells (TIICs) from gastric cancer patients.PBMCs from healthy donors and TIICs from gastric cancer patients were treated with lidocaine.
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Lidocaine Modulates Cytokine Production and Enhances Anti-Tumor Immune Response in Gastric Cancer: Dual Effects on Normal Peripheral Blood Mononuclear Cells and Primary Gastric Tumor-Infiltrating Immune Cells

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By Yi-Ying Wu, I-Chun Chen, Ming-Shan Chen, Feng-Hsu Wu
| preprints.org
Preprint Article Version 1 This version is not peer-reviewed Version 1 : Received: 11 October 2024 / Approved: 11 October 2024 / Online: 11 October 2024 (06:13:46 CEST) Wu, Y.-Y.; Chen, M.-S.; Chen, I.-C.; Wu, F.-H.; Liao, T.-L.; Wen, H.-W.; Nielsen, B. L.; Liu, H.-J. Lidocaine Modulates Cytokine Production and Enhances Anti-Tumor Immune Response in Gastric Cancer: Dual Effects on Normal Peripheral Blood Mononuclear Cells and Primary Gastric Tumor-Infiltrating Immune Cells.
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