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Yingyu Chen

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Articles

TMEM189/PEDS1 deficiency aggravates MASH progression by promoting FASN-mediated macrophage activation

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By Pengli Guo, Jinqiu Feng, Tao Li, Yongjun Zhang, Chunlei Wang, Ping Lv, Zongming Zhang, Yingyu Chen, Yaxin Lou, Shufang Ye
| Nature Verified
Abstract Transmembrane protein 189 (TMEM189), also known as plasmanylethanolamine desaturase 1 (PEDS1), is involved in plasmalogen biosynthesis, phospholipid metabolism, ferroptosis, and autophagy. However, whether TMEM189/PEDS1 regulates macrophages and disease-related inflammatory responses remains unclear. Here, we for the first time investigated the contribution of TMEM189/PEDS1 to macrophage activation and progression of metabolic dysfunction-associated steatohepatitis (MASH).
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High-capacity optical communication relayed by multi-core amplifier on deployed submarine seven-core fiber cable

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By Yingyu Chen, Hanyu Gao, Yongguang Xiao, Jinpei Li, Wenhao Li, Ruqi Chen, Jiajing Tu, Cheng Du, Lei Shen, Yuelin Yan, Guangquan Wang, Ying Yu, Zhengyong Liu, Shecheng Gao, Zhaohui Li, Chao Lu, Jinkai Zhou, Yaolin Wu, Bofan Guo, Runzhou Qiu, Xiaozhen Xie
| Nature Verified
Abstract Space division multiplexing (SDM), particularly multi-core fiber (MCF) technology, represents a promising solution for high-density cabling in duct-constrained scenarios such as submarine cable systems. Although recent laboratory experiments and prototype trials have demonstrated the feasibility of MCF-based submarine cables, a complete optical communication validation of a real-world MCF submarine cable link incorporating optical amplifiers has remained a critical necessity.
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PDCD5 promotes substrate release from the TRiC complex in cilia and flagella

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By Huafang Wei, Qianqian Song, Liying Wang, Qiong Deng, Bingbing Wu, Yinghong Chen, Tingting Han, Yueshuai Guo, Zuyang Li, Fucheng Dong, Shuang Ma, Qiaoyu Zhao, Xiangyi Shi, Chen Pan, Wanying Jiang, Xiaofei Liu, Yingyu Chen, Renjie Jiao, Li Yuan Verified, Chao Liu, Xuejiang Guo, Yao Cong, Wei Li
| Cell Press Verified
ArticleVolume 86, Issue 2p376-392.e11Open access 1Guangzhou Women and Children's Medical Center, Sino-French Hoffmann Institute, Guangzhou Medical University, Guangzhou 510623, China 2Key Laboratory of RNA Innovation, Science and Engineering, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai 200031, China 3Department of Urology, The People's Hospital of Longhua,...
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