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Yingze Zhao on Muck Rack

Yingze Zhao

As seen in: Nature, MDPI, Cell Press
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Articles

T cell immune evasion by SARS-CoV-2 JN.1 escapees targeting two cytotoxic T cell epitope hotspots - Nature Immunology

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By Yuanyuan Guo, Jianxun Qi, Kefang Liu, Shuguang Tan, Yingze Zhao, Jikun Zhou, Rui Song, George F. Gao
| Nature Verified
Abstract Although antibody escape is observed in emerging severe acute respiratory syndrome coronavirus 2 variants, T cell escape, especially after the global circulation of BA.2.86/JN.1, is unexplored. Here we demonstrate that T cell evasion exists in epitope hotspots spanning BA.2.86/JN.1 mutations. The newly emerging Q229K at this conserved nucleocapsid protein site impairs HLA-A2 epitope hotspot recognition.
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Dual-Channel Mapping-Gas Column Concentration Inversion Method Based on Multispectral Imaging

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By Yingze Zhao, Baixuan Zhao, Kaifeng Zheng, Ninghao Shi
| MDPI
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
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Single-Cell Sequencing of Peripheral Mononuclear Cells Reveals Distinct Immune Response Landscapes of COVID-19 and Influenza Patients

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By Linnan Zhu, Penghui Yang, Yingze Zhao, Zhenkun Zhuang
| Cell Press Verified
Highlights • We generated a single-cell atlas of PBMCs in both COVID-19 and influenza patients • Plasma cells increase significantly in both COVID-19 and influenza patients • COVID-19 is featured with XAF1-, TNF-, and FAS-induced T cell apoptosis • COVID-19 activates distinct pathway (STAT1/IRF3) versus influenza (STAT3/NFκB) Summary The coronavirus disease 2019 (COVID-19) pandemic poses a current world-wide public health threat.
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