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As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.Articles
A universal 6iL/E4 culture system for deriving and maintaining embryonic stem cells across mammalian species
Abstract The derivation of authentic embryonic stem cells (ESCs) across mammalian species remains a major challenge. Here, we report the development of a defined, serum-free culture system, termed 6iL/E4, that enables the derivation and long-term self-renewal of ESCs across diverse mammalian species. Through systematic dissection of signaling pathways, we identified conserved regulatory modules involving GSK3α, WNT, STAT3, PDGFR, and MEK/ERK signaling.
Moisturizer Based on Multi‐Targeted Skin Barrier Repair Conception: Evidence From In Vitro and Clinical Evaluations
Background Skin barrier dysfunction is a key driver of skin sensitivity and inflammatory dermatoses. However, the long-term efficacy of existing moisturizers remains limited. This study aimed to evaluate the efficacy of a moisturizer formulated with target skin disruption, lock in moisture, connect skin cells (TLC) technology using in vitro and clinical evaluations.
Single-cell transcriptional landscapes of bovine peri-implantation development
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