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Photoredox-Catalyzed Dearomative Ipso -Cyclization of N -Aryl Propiolamides with N -Allyl Bromodifluoroacetamides to Access α , α -Difluoro- γ -Lactam-Substituted Azaspiro[4.5]trienones
Conflicts of Interest The authors declare no conflicts of interest. Data Availability Statement The data that supports the findings of this study are available in the supplementary material of this article.
Inorganic nitrogen metabolic reprogramming of the gut microbiome drives fecal microbiota transplantation in ulcerative colitis
Abstract Although fecal microbiota transplantation (FMT) shows promise for ulcerative colitis (UC), its clinical success appears to be contingent upon the degree of donor microbiota engraftment. Using an LD50-based ecological model, our study reveals that inorganic nitrogen utilization capacity (IN-uc) critically determines gut microbial assembly in high oxidative stress environments, which significantly influences microbial engraftment outcomes.
China & World Economy | IWEP & CASS Economics Journal | Wiley Online Library
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