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Zhihong Hu on Muck Rack

Zhihong Hu

Wuhan
As seen in: Nature, Wiley Online Library, PLOS ONE, Journal of Clinical Pathology, MDPI, ACS Publications, Cell Press, OSLI Retina, Optica, Texas Medical Center and
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Articles

Dissociation and reassembly of the trimeric ectodomain of a baculoviral fusion protein during low-pH treatment

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By Tingting Chong, Guibo Rao, Heya Na, Chao Leng, Fanxing Meng, Manli Wang, Peng Gong, Zhihong Hu, Sheng Cao, Kexing Tian, Yaozhou Liang
| Cell Press Verified
Keywords class I membrane fusion protein fusion intermediate cryo-electron microscopy baculovirus fusion peptide Get full text access Log in, subscribe or purchase for full access. References 1. White, J.M. ∙ Ward, A.E. ∙ Odongo, L. ... Viral Membrane Fusion: A Dance Between Proteins and Lipids Annu. Rev. Virol. 2023; 10:139-161 2. Colman, P.M. ∙ Lawrence, M.C. The structural biology of type I viral membrane fusion Nat. Rev. Mol. Cell Biol. 2003; 4:309-319 3. Kielian, M.
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RNA synthesis and substrate analog inhibition in the CCHFV polymerase

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By Hengxia Jia, Bo Tang, Shunli Liu, Xin Wen, Fan Wu, Xiao Hu, Hu Zhou, Tingting Chong, Qiaojie Liu, Guibo Rao, Mingyu Wei, Xuping Jing, Sheng Cao, Fei Deng, Zhihong Hu, Bo Shu, Rui Gong, Jiqin Wu, Manli Wang, Peng Gong, Lincan Lv
| Nature Verified
Abstract The about 4000-residue L proteins from the Nairoviridae are the largest known viral polymerases, lacking global structural information and promising nucleotide analog (NA) inhibitors. Here we report structures of full-length Nairoviridae Crimean-Congo hemorrhagic fever virus (CCHFV) L including a 3.0-Å-resolution polymerase elongation complex that elucidates mechanisms of both early and late elongation stages.
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Splenic B‐Cell Lymphoma/Leukemia With TCL1 Gene Rearrangement

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By Xin Wang, Guilin Tang, Zhihong Hu
| Wiley Online Library Verified
Background Splenic B-cell lymphoma/leukemia includes a group of indolent small B-cell lymphomas/leukemias that share overlapping morphological and immunophenotypic features, making accurate diagnosis challenging. Specific gene rearrangements have not been commonly associated with splenic B-cell lymphomas/leukemias, and the TCL1 gene rearrangement—characteristic of T-cell prolymphocytic leukemia—has not been previously reported in B-cell lymphomas/leukemias.
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