Barbara Sitek

Identification of significant differentially expressed genes and proteins in blood samples through proteomic analyses and RNA microarrays as the basis for the development of predictive models Collection and integration of clinical data Development of a delirium prediction model based on ML, combining clinical data with data from proteomics and genetics Ethical Considerations Patient Recruitment Textbox 1. Inclusion and exclusion criteria of the study.

1Amsterdam UMC, location Vrije Universiteit Amsterdam, Department of Medical Oncology, OncoProteomics Laboratory, De Boelelaan 1117, Amsterdam, the Netherlands 2Cancer Center Amsterdam, Imaging and Biomarkers, Amsterdam, the Netherlands 3School of Medicine, Westlake University, Hangzhou, Zhejiang, China 4Westlake Center for Intelligent Proteomics, Westlake Laboratory of Life Sciences and Biomedicine, Hangzhou, Zhejiang, China 5Amsterdam UMC location Vrije Universiteit Amsterdam, Department of...

For this study, tracheal tissue was obtained from healthy donors of lung transplants through the Department Clinic for Thoracic and Cardiovascular Surgery (University Hospital Essen). General selection criteria for lung transplant donors are listed in the Eurotransplant guidelines (https://www.eurotransplant.org/wp-content/uploads/2022/02/H1-Introduction-July-28-2016.pdf). Tissue was resected during the course of size adaptations of the donor lung before transplantation into the recipient.