Bjørt K. Kragesteen on Muck Rack

Bjørt K. Kragesteen

As seen in: Nature, Cell Press
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Articles

Comparative single-cell analyses reveal evolutionary repurposing of a conserved gene programme in bat wing development - Nature Ecology & Evolution

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By Christian Feregrino, Silvia Aldrovandi, Anna A. Monaco, Alessa Ringel, Ariadna Morales, Tobias Zehnder, Rose Yinghan Behncke, Juliane Glaser, Alexander M. Barclay, Guillaume Andrey, Bjørt K. Kragesteen, René Hägerling, Stefan A. Haas, Martin Vingron, Igor Ulitsky, Julio C. Hechavarría, Nicolas Fasel, Michael Hiller, Darío G. Lupiáñez, Stefan Mundlos
| Nature Verified
Abstract Bats are the only mammals capable of self-powered flight, an evolutionary innovation based on the transformation of forelimbs into wings. The bat wing is characterized by an extreme elongation of the second to fifth digits with a wing membrane called the chiropatagium connecting them. Here we investigated the developmental and cellular origin of this structure by comparing bat and mouse limbs using omics tools and single-cell analyses.
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The transcriptional and regulatory identity of erythropoietin producing cells - Nature Medicine

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By Bjørt K. Kragesteen, Baoguo Li, Ken Xie, Truong San Phan, Roberto Avellino, Thorfinn S. Korneliussen, Josef T. Prchal, Olga M. Lempke, Andreas M. Bapst, Roland H. Wenger
| Nature Verified
Author notes These authors contributed equally: Bjørt K. Kragesteen, Amir Giladi, Eyal David, Shahar Halevi, Fernando Racimo, Eske Willerslev, Chamutal Gur, Roland H. Wenger, Ido Amit. These authors supervised this work: Chamutal Gur, Roland H. Wenger, Ido Amit. Authors and Affiliations Department of Systems Immunology, Weizmann Institute of Science, Rehovot, Israel Bjørt K.
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Dynamic 3D chromatin architecture contributes to enhancer specificity and limb morphogenesis

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By Malte Spielmann, Bjørt K. Kragesteen, Christina Paliou, Verena Heinrich
| Nature Verified
a, cHi-C subtraction between wild-type and Neurog1del/del mutant forelimb tissue at E11.5. Chromatin interactions more prevalent in mutant or wild-type forelimb tissues are shown in red and blue, respectively. Significant changes are highlighted in black boxes (FDR = 0.05). Right, Neurog1del/del embryos do not show changes in Pitx1 expression in E11.5 forelimbs as seen in WISH (photo) and quantified by qRT–PCR.
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