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Articles by Chun Zhou
Towards a better legal framework for overseas investment insurance: China’s challenge under the belt and road initiative
ABSTRACT The Belt and Road Initiative (BRI) offers Chinese enterprises unprecedented opportunities for global expansion, but also exposes them to significant political risks in many host countries. Overseas Investment Insurance (OII) is a useful mechanism for mitigating such risks.
Moored observations of the deep western boundary current east of the Gagua Ridge in the Northwestern Pacific
Abstract The deep western boundary current (DWBC) of the Pacific serves as a lower limb of the meridional overturning circulation that has been identified as a key component of the global climate system. Here, we report the results of observations from a set of full-depth subsurface moorings deployed in the Northwestern Pacific from August 2017 to May 2020.
Learning conjugate fringe decomposition for single-shot fringe projection profilometry
Non-contact 3D surface measurement from a single exposure hinges on the accuracy and generalization of phase demodulation. Traditionally, in fringe projection profilometry (FPP), depth is not measured directly but inferred from the phase of a projected fringe, so demodulating phase from a single image is the central step.
Structural basis of laminin mimicry by E. coli CNF1 and its therapeutic potential for cancer immunotherapy
Abstract The E. coli CNF1 toxin hijacks the host laminin 511 receptor, Lu/BCAM, to enter cells. Here, we present the high-resolution cryo-EM structures of full-length CNF1, the CNF1-BCAM complex, and the physiological laminin 511-BCAM complex. Structural analysis uncovers that CNF1 targets the V2 domain of BCAM, mimicking the interaction mode of laminin 511.
A Polarity-Sensitive FLIM Probe With Large Lifetime Dynamic Range for Visualizing Intracellular Lipid Droplets
Conflicts of Interest The authors declare no conflicts of interest. Data Availability Statement The data that supports the findings of this study are available in the Supporting Information of this article. Supporting Information Filename Description chem71638-sup-0001-SuppMat.docx1.9 MB Materials and methods, synthetic details, supporting figures and tables, and spectral data are given in the Supporting Information.
β3-AR/β-arrestin2 Interaction Triggers Cardiac Fibrosis Through JNK/c-Jun Pathway in Cardiac Fibroblasts
1 Introduction Myocardial fibrosis (MF) is a pivotal pathological driver of heart failure (HF) resulting from various cardiac diseases. It is characterised by abnormal deposition of extracellular matrix and disorganisation of perivascular collagen, leading to impaired myocardial stiffness, contractility, and coronary reserve [1].
Circularly Polarized Lasing and Ultrafast Optical Helicity Switching in Chiral Perovskite Microcavities
Chun Zhou, Jiqing Tan and Yongsheng Hu contributed equally to this work. Conflicts of Interest The authors declare no conflicts of interest. Data Availability Statement The data that support the findings of this study are available from the corresponding author upon reasonable request. Supporting Information Filename Description adma74308-sup-0001-SuppMat.docx24.8 MB Supporting File: adma74308-sup-0001-SuppMat.docx.
Near-optimal discrimination of displaced squeezed binary signals using displacement, inverse-squeezing, and photon-number-resolving detection
5 hours ago The decision gutting the Voting Rights Act has commenced the largest rollback of Black representation in the South since the end of Reconstruction. The Supreme Court’s decision gutting the Voting Rights Act in Louisiana v. Callais has commenced the largest rollback of Black political representation …
Near-optimal discrimination of displaced squeezed binary signals using displacement, inverse-squeezing, and photon-number-resolving detection
Abstract We propose an inverse-squeezing Kennedy receiver for discriminating binary phase-shift-keyed displaced squeezed vacuum states. The receiver combines a Kennedy-type nulling displacement, an orthogonally oriented inverse-squeezing operation and photon-number-resolving detection with a maximum-a-posteriori threshold rule.
Catalytic Proximal Protein Oligomerization as an Anti-Tumor Strategy Targeting WDR5
Abstract Inducing protein oligomerization holds therapeutic promise, yet identifying or rationally designing effective inducers remains challenging. In this study, we leverage nanopore technology to screen small molecules capable of modulating WD repeat domain 5 (WDR5) protein oligomerization and uncover a oligomerization mechanism which we term Catalytic Proximal Protein Oligomerization (CaPPO).
Mechanistic insights into the structure and function of the RecA C-terminal tail - Communications Biology
Abstract Bacterial RecA protein oligomerizes on single-stranded DNA (ssDNA) in the presence of ATP to form an active filament, RecA*, which is essential for homologous recombination and the activation of bacterial DNA damage response (SOS response). Despite extensive studies on the structure and function of RecA and RecA*, the exact function of the RecA flexible C-terminal tail remains poorly understood. Here, we report the crystal structure of the full-length RecA protein from K.
Weak self-induced cooling of tropical cyclones amid fast sea surface warming - Nature Geoscience
Abstract Sea surface temperature directly beneath tropical cyclones is crucial for their intensification. In the long term, global warming heats the surface oceans, intensifying tropical cyclones, whereas concurrently with a cyclone, inner-core surface cooling is induced by the cyclone itself curtailing its intensification. However, the magnitude of cyclone-induced cooling, or the trend in storm-local sea surface temperature, remains uncertain.
Association of regular paracetamol or ibuprofen usage with the risk of incident kidney stones
CONFLICT OF INTEREST STATEMENT No disclosure was reported. DATA AVAILABILITY STATEMENT The UK Biobank data are available on application to the UK Biobank, and the analytic methods, and study materials that support the findings of this study will be available from the corresponding authors on request. Supporting Information Filename Description bcp70342-sup-0001-supplemental_materials.docxWord 2007 document , 449.1 KB Figure S1. Flow chart of the study participants. Figure S2.
Tailoring the Microstructure and Electronic Properties of CsPbBr3 Perovskite Films: Toward High‐Efficiency Light‐Emitting Diodes
Conflict of Interest The authors declare no conflict of interest. Data Availability Statement The data that support the findings of this study are available from the corresponding author upon reasonable request. Supporting Information Filename Description smll71172-sup-0001-SuppMat.pdf2 MB Supporting Information References 1, , , , , , , , , Adv. Mater. 2022, 34, 2204460. 2, , , , ChemSusChem 2024, 17, 202301205. 3, , , , , , , , , , , , , , , , , , , , , , , , , Matter 2024, 7, 1054.
Experimental demonstration of decoy-three-state quantum key distribution with advantage distillation
The advantage distillation (AD) method can significantly improve the bit error rate tolerance and transmission distance for different quantum key distribution (QKD) protocols. To enhance the transmission distance in a decoy-three-state QKD protocol, we analyze security using the AD method for the decoy-three-state QKD protocol with a weak-coherent source.
Image Quality Improvement and Artificial Intelligence Performance in Pulmonary Embolism Detection at Deep Learning Reconstruction-Based Ultra-low Radiation Dose CT Pulmonary Angiography
Abbreviations DLR (deep learning reconstruction) ULD (ultra-low dose) CTPA (CT pulmonary angiography) AI (artificial intelligence) PE (pulmonary embolism) RD (routine-dose) HIR (hybrid-iterative reconstruction) CNR (contrast-to-noise ratio) Key Words CT pulmonary angiography Pulmonary embolism Ultra-low dose Deep learning reconstruction Artificial intelligence Get full text access Log in, subscribe or purchase for full access. REFERENCES 1.
Bispecific killer cell engager-secreting CAR-T cells redirect natural killer specificity to enhance antitumour responses - Nature Biomedical Engineering
Abstract T cells and natural killer (NK) cells collaborate to maintain immune homeostasis. Current cancer immunotherapies predominantly rely on the individual application of these cells. Here we use bicistronic vectors to co-express chimeric antigen receptors (CARs) and secreted immune cell engagers (ICEs), leveraging the combined therapeutic potential of both effector cell types.
Mid‐Infrared and Telecom Band Two‐Color Entanglement Source for Quantum Communication
Conflict of Interest The authors declare no conflict of interest. Supporting Information Filename Description lpor70168-sup-0001-SuppMat.docx4.3 MB Supporting Information References 1, , , , , , Phys. Rev. Lett. 70, 1895. 2, , , , , , Nat. Commun. 2022, 13, 7878. 3, , , , , , , , , , , , , , , , , , , , , , , , Science 2020, 370, 1460. 4, , , , , , , , , , Phys. Rev. Lett. 2019, 123, 190401. 5, , , , , , , Sci. Adv. 2021, 7, abd2986. 6, , , , , , , , , , , Nat. Commun. 9, 93. 7, , , , , , Phys. Rev. Lett.
Radiotherapy enhances anticancer CD8 T cell responses by cGAMP transfer through LRRC8A/C volume-regulated anion channels
Editor’s summary Volume-regulated anion channels (VRACs) transport a wide range of solutes across the cell membrane and are critical to regulating cell volume. Cao et al. now show that the leucine-rich repeat–containing 8A/C (LRRC8A/C) VRAC can transport cyclic GMP-AMP (cGAMP) from irradiated cancer cells into T cells within tumors to enhance their antitumor effector responses.
A story matters: Embedding arguments into a narrative to induce regulatory construal fit in persuasive health messages
Advanced search Atlantic Journal of Communication Latest Articles Submit an article Journal homepage Full Article Figures & data References Citations Metrics Reprints & Permissions Read this article /doi/full/10.1080/15456870.2025.2511216?needAccess=true ABSTRACT Persuasion literatures have focused on regulatory fit effect, that a message is more persuasive if satisfying the promotion or prevention focus of recipients.
CD97-directed CAR-T cells with enhanced persistence eradicate acute myeloid leukemia in diverse xenograft models
Keywords: acute myeloid leukemia CD97 chimeric antigen receptor immunotherapy exhaustion Introduction Acute myeloid leukemia (AML) is a prevalent acute leukemia in adults, characterized by the blocked differentiation and abnormal proliferation of immature myeloid cells, leading to hematopoietic disorder and life-threatening cytopenia. The incidence rate of AML tends to increase gradually with age, along with a decline in overall survival.
Construction and application of clinical trial criteria for physical r
Back to Journals » Journal of Multidisciplinary Healthcare » Volume 18 Authors Luo R, Yu M, Zhou C, Wang Y, Liu C, Zhang X, Chen T Received 19 May 2025 Accepted for publication 29 October 2025 Published 10 December 2025 Volume 2025:18 Pages 7919—7931 DOI https://doi.org/10.2147/JMDH.S541461 Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 2 Editor who approved publication: Professor Charles V Pollack Ronghong Luo,1 Meiling Yu,1 Chun Zhou,2 Ya Wang,3...
A Study of Discourse on COVID-19 Vaccines from Conspiracy Communities on Reddit Using Topic Modeling and Sentiment Analysis
Advanced search Health Communication Latest Articles Submit an article Journal homepage Full Article Figures & data References Supplemental Citations Metrics Reprints & Permissions Read this article /doi/full/10.1080/10410236.2025.2505212?needAccess=true ABSTRACT Given the limited research on the content attributes of anti-vaccination discourse regarding COVID-19 vaccines, our study investigated how conspiracy communities on Reddit, which may serve as potential anti-vaccination groups, have...
ZBP1 senses spliceosome stress through Z-RNA:DNA hybrid recognition
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ArticleVolume 85, Issue 9p1790-1805.e7 1Zhejiang Key Laboratory of Molecular Cancer Biology, Life Sciences Institute, Zhejiang University, Hangzhou 310058, China 2Department of Neonatal Surgery, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou 310052, China 3State Key Laboratory of Marine Food Processing & Safety Control, College of Food Science and Engineering, Ocean University of China, No. 1299 Sansha Road, Qingdao...
By Jianfeng He, Yongyi Zhu, Zichao Tian, Mengqin Liu, Anmin Gao, Wangmi Fu, Fei Lu, Yutong Sun, Yajun Guo, Rongqing Pan, Yuchen Ji, Jianxiang Chen, Huasong Lu, Juan Lin, Xingguo Liang, Chun Kim Verified, Chun Zhou, Huipeng Jiao
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Cell Press
Verified
Collective Excitonic Assembly in Perovskite Superlattice
1 Introduction Understanding, protecting, and manipulating quantum coherence is crucial for implementing photon-based quantum information technologies.[1] Quantum dots (QDs), with their ultra-high density of states resulting from quantum confinement effects, are particularly well-suited for all-optical gate operations in ultrafast quantum information processing.[2, 3] Unlike other inorganic semiconductor QDs, cesium lead halide ( CsPbX 3 ${\rm CsPbX}_3$ , where X = Cl, Br, or I) perovskite...
Structure and catalytic mechanism of exogenous fatty acid recycling by AasS, a versatile acyl-ACP synthetase - Nature Structural & Molecular Biology
Abstract Fatty acids (FAs) are essential building blocks for all the domains of life, of which bacterial de novo synthesis, called type II FA synthesis (FAS II), is energetically expensive. The recycling of exogenous FAs (eFAs) partially relieves the FAS II demand and, therefore, compromises the efficacy of FAS II-directed antimicrobials. The versatile acyl-acyl carrier protein (ACP) synthetase, AasS, enables bacterial channeling of diverse eFA nutrients through holo-ACP, an activated form of ACP.
A bacterial methyltransferase that initiates biotin synthesis, an attractive anti-ESKAPE druggable pathway
Research Article STRUCTURAL BIOLOGY INTRODUCTION The water-soluble vitamin B7, biotin, is an indispensable micronutrient throughout the three domains of life (1). Unlike plants and most of bacterial species that program biotin synthesis pathways (1), humans cannot make this coenzyme. In general, gut commensals behave as a major group of biotin suppliers for mammalian biotin-dependent carboxylases/decarboxylases (2, 3).
Few-cycle 12.5-GW pulses generated via efficient all-solid-state post-compression from an ytterbium laser
In contrast to the more conventional gas-filled post-compression technique, solid-state-based multi-pass cells and multiple plates allow for the robust and efficient generation of intense few-cycle pulses from ytterbium (Yb) lasers with moderate energies. In this Letter, 180-fs 200-μJ pulses at 50 kHz were efficiently compressed down to 6.9 fs 144 μJ, enhancing the peak power from 1.1 GW to 12.5 GW with a long-term power stability of 0.1%.
Radiological features on high-resolution MR imaging predicts successful recanalization in patients with symptomatic chronic intracranial large artery occlusion
Key Words Chronic occlusion Intracranial large artery occlusion Radiological features Endovascular recanalization Predictors Get full text access Log in, subscribe or purchase for full access. References 1. Kuroda, S. ∙ Houkin, K. ∙ Kamiyama, H. ... Long-term prognosis of medically treated patients with internal carotid or middle cerebral artery occlusion: can acetazolamide test predict it? Stroke. 2001; 32:2110-2116 2. Wang, Y. ∙ Zhao, X. ∙ Liu, L. ... CICAS Study Group.
Runoff Simulation in Data-Scarce Alpine Regions: Comparative Analysis Based on LSTM and Physically Based Models
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Ocean internal tides suppress tropical cyclones in the South China Sea - Nature Communications
Abstract Tropical Cyclones (TCs) are devastating natural disasters. Analyzing four decades of global TC data, here we find that among all global TC-active basins, the South China Sea (SCS) stands out as particularly difficult ocean for TCs to intensify, despite favorable atmosphere and ocean conditions.
Effects of Substrate Composition on the Growth Traits of Grafting Seedling in Macadamia Nuts
Preprint Article Version 1 This version is not peer-reviewed Version 1 : Received: 23 April 2024 / Approved: 23 April 2024 / Online: 23 April 2024 (14:56:46 CEST) Tan, Q.J.; Zhou, C.H.; Xu, P.; Huang, X.Y.; Wei, Y.R.; Pan, Z.Z.; Wang, W.L.; Wang, L.F. Effects of Substrate Composition on the Growth Traits of Grafting Seedling in Macadamia Nuts. Preprints 2024, 2024041539.
Using 1/2 Descending Time in CEUS to Identify Renal Allograft Rejection
Rationale and Objectives This study investigates the potential of quantitative Contrast-Enhanced Ultrasound (CEUS) parameters to distinguish between graft dysfunction due to rejection and non-rejection in kidney transplant recipients. Methods In this retrospective study, 50 kidney transplant patients who presented elevated serum creatinine or proteinuria were analyzed. They were categorized as rejection or non-rejection based on biopsy outcomes.
Observations of Parametric Subharmonic Instability of Diurnal Internal Tides in the Northwest Pacific
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Cyclosporine A-resistant CAR-T cells mediate antitumour immunity in the presence of allogeneic cells - Nature Communications
Abstract Chimeric antigen receptor (CAR)-T therapy requires autologous T lymphocytes from cancer patients, a process that is both costly and complex. Universal CAR-T cell treatment from allogeneic sources can overcome this limitation but is impeded by graft-versus-host disease (GvHD) and host versus-graft rejection (HvGR).
Vacuum Processed Metal Halide Perovskite Light‐Emitting Diodes
Conflict of Interest The authors declare no conflict of interest. References 1, , , , , , , , , , Nano Lett. 2023, 23, 985. 2, , , , , , , , Nanoscale 2023, 15, 2837. 3, , , , , , , , , Adv. Funct. Mater. 2022, 33, 2209186. 4, , , , , , , , , , , , , , Nat. Nanotechnol. 2014, 9, 687. 5, , , , , , , , , , , , , Nature 2022, 611, 688. 6, , , , , , , , , , , , Small 2021, 17, e2101477. 7, , , , , , , , , , , , , , , , , , , , , , , , , , Nat. Commun. 2021, 12, 5081. 8, , , , , , , , , , , , , , , , Nat. Commun.
Vacuum Processed Metal Halide Perovskite Light‐Emitting Diodes
Conflict of Interest The authors declare no conflict of interest. References 1, , , , , , , , , , Nano Lett. 2023, 23, 985. 2, , , , , , , , Nanoscale 2023, 15, 2837. 3, , , , , , , , , Adv. Funct. Mater. 2022, 33, 2209186. 4, , , , , , , , , , , , , , Nat. Nanotechnol. 2014, 9, 687. 5, , , , , , , , , , , , , Nature 2022, 611, 688. 6, , , , , , , , , , , , Small 2021, 17, e2101477. 7, , , , , , , , , , , , , , , , , , , , , , , , , , Nat. Commun. 2021, 12, 5081. 8, , , , , , , , , , , , , , , , Nat. Commun.
Habitual glucosamine use, APOE genotypes, and risk of incident cause-specific dementia in the older population - Alzheimer's Research & Therapy
Of the 214,945 participants included, the mean age was 64.1 (SD: 2.9) years, 113,476 (52.8%) participants were female, and 52,893 (24.6%) participants were habitual glucosamine users. The characteristics of the participants by using glucosamine supplement or not are showed in Table 1.
Variability of the Deep Western Boundary Current in the Northern Philippine Sea
Abstract The deep western boundary current (DWBC) was studied based on a full-depth mooring east of Luzon Island in the Northern Philippine Sea deep basin during the period from January 2018 to May 2020. On average, the DWBC in the Philippine Sea flows southward with a velocity of approximately 1.18 cm s−1 at a depth of 3050 m. Significant intraseasonal and seasonal variations of the DWBC are identified.
Bre1/RNF20 promotes Rad51-mediated strand exchange and antagonizes the Srs2/FBH1 helicases - Nature Communications
Abstract Central to homologous recombination (HR) is the assembly of Rad51 recombinase on single-strand DNA (ssDNA), forming the Rad51-ssDNA filament. How the Rad51 filament is efficiently established and sustained remains partially understood.
IRF3-mediated lncRNA FTX promotes cell proliferation, migration, invasion and suppresses cell apoptosis in oral squamous cell carcinoma by up-regulating FCHSD2 via miR-708-5p - PubMed
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Comparing the Contributions of Temperature and Salinity Changes to the AMOC Decline at 26.5°N
Abstract At 26.5°N in the North Atlantic, a continuous transbasin observational array has been established since 2004 to detect the strength of the Atlantic meridional overturning circulation. The observational record shows that the subtropical Atlantic meridional overturning circulation has weakened by 2.5 ± 1.5 Sv (as mean ± 95% interval; 1 Sv ≡ 106 m3 s−1) since 2008 compared to the initial 4-yr average.
Spatial-temporal characteristics of the oceanic bottom mixed layer in the South China Sea
1 Introduction The oceanic bottom mixed layer (BML) is a portion of the water column adjacent to the seafloor, generally characterized by a vertically homogeneous or quasi-homogeneous profile for the temperature, salinity, density, and other seawater properties (Huang et al., 2019).
The vertical structure and variability of currents east of Philippines from mooring measurements during the 2015/2016 El Niño
Yansong Liu1,2,3, Qiang Ren1,2,3*, Fei Yu1,2,3,4*, Chuanjie Wei1, Xinyuan Diao1 and Feng Nan1,2,3 1Institute of Oceanology, Chinese Academy of Sciences, Qingdao, China 2Key Laboratory of Ocean Circulation and Waves, Institute of Oceanology, Chinese Academy of Sciences, Qingdao, China 3Laboratory for Ocean and Climate Dynamics, Qingdao National Laboratory for Marine Science and Technology, Qingdao, China 4University of Chinese Academy of Sciences, Qingdao, China Surface and Subsurface currents...
Walking pace, handgrip strength, age, APOE genotypes, and new-onset dementia: the UK Biobank prospective cohort study - Alzheimer's Research & Therapy
Population and study design The UK Biobank is a population-based cohort of more than 500,000 participants who attended 1 of 22 assessment centers across the UK between 2006 and 2010. At enrollment, participants completed a touch-screen questionnaire, had physical measurements taken, and provided biological samples, as described in detail elsewhere [29, 30].
Optimized design of block copolymers with covarying properties for nanolithography - Nature Materials
Abstract The ability to impart multiple covarying properties into a single material represents a grand challenge in manufacturing. In the design of block copolymers (BCPs) for directed self-assembly and nanolithography, materials often balance orthogonal properties to meet constraints related to processing, structure and defectivity. Although iterative synthesis strategies deliver BCPs with attractive properties, identifying materials with all the required attributes has been difficult.
Lignin to Value-Added Chemicals and Advanced Materials：Extraction, Degradation, and Functionalization
Lignin to Value-Added Chemicals and Advanced Materials：Extraction, Degradation, and Functionalization Mei Jiao Gan, Yu Qin Niu, Xue Jing Qu and Chun Hui Zhou Abstract Lignin is one of green and sustainable feedstocks for producing chemicals and materials, and yet it is far from being utilized. Over the past decade, remarkable progress in the extraction, catalytic depolymerization, and chemical functionalization of lignin and the fabrication of lignin-containing materials has been made.
Cleaner One-Pot Transformation of Glycerol to Acrylic Acid and 1,2-Propanediol over Cu2O/Montmorillonite Bifunctional Catalysts Without External Oxygen and Hydrogen
Cleaner One-Pot Transformation of Glycerol to Acrylic Acid and 1,2-Propanediol over Cu2O/Montmorillonite Bifunctional Catalysts Without External Oxygen and Hydrogen Chaopeng Fu, Qiming She, Riccardo Tesser and Chun Hui Zhou Abstract Efficient conversion of glycerol, an inevitable by-product of the transesterification process producing biodiesel, to acrylic acid (AA) and 1,2-propanediol (1,2-PDO) via a cleaner process is much attractive and challenging.
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