CINCINNATI (WXIX) - A major stretch of southbound Interstate 75 will close this weekend as part of demolition work for the Brent Spence Bridge Corridor project. Starting at 11 p.m. Friday, all southbound lanes will close between Freeman Avenue and the Ninth Street Viaduct and will not reopen until 5 a.m. Monday. The Freeman Avenue exit will remain open all weekend. The Ohio Department of Transportation is urging drivers, especially trucks, to detour east on the Norwood Lateral to southbound I-71.