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Articles by Guiling Li
Validation of Automated Fragmented Red Cell Count by the Sysmex XN‐9000: Correlation With Microscopy and Impact of Microcytosis/Hypochromia
Validation of Automated Fragmented Red Cell Count by the Sysmex XN‐9000: Correlation With Microscopy and Impact of Microcytosis/Hypochromia - Cai - International Journal of Laboratory Hematology - Wiley Online Library
Latent profile analysis of sleep quality and associated factors on sleep patterns in night-shift nurses: a cross-sectional study
Abstract Objective: This study aimed to investigate the potential categories of sleep quality in shift nurses using latent profile analysis, and to explore the characteristics and associated factors of sleep quality in each category. Methods: Convenience sampling was used to select 1,650 shift nurses from four tertiary A-level hospitals from May to June 2025.
Environmental factors shape the intestinal microbiota and function of Manila clam Ruditapes philippinarum
Abstract Intestinal microbiota of aquatic animals is closely associated with the environment, influencing their health, immune defense, and environmental adaptability. To understand the relationships among the Manila clam (Ruditapes philippinarum) intestinal microbiota, the bacterial communities in their habitats, and environmental factors, as well as the characteristics and potential functions of the intestinal microbiota.
Fruquintinib plus sintilimab in advanced cervical cancer: an open-label, multicentre, phase 2 study
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Abstract Efficacy of second-line treatments after first-line platinum-based chemotherapy in advanced cervical cancer is modest. This open-label, single-arm, multicentre, proof-of-concept phase 2 study evaluated fruquintinib plus sintilimab in advanced cervical cancer. Patients recruited between July 2021 and June 2022 had received at least first-line platinum-based chemotherapy or were unable to receive standard treatment in China.
By Xiaohua Wu, Danbo Wang, Jing L. Wang, Yi Huang, Guiling Li, Jieqing Zhang, Keming Wang, Yu Kang, Anwen Liu, Xiaotian Han, Xuemei Ren, Runfeng Yang, Qing Yang, Bingbing Zhao, Juan Wang, Hanjie Yi, Yue Tan, Keyan Chen, Haiyan Shi, Songhua Fan, Michael Shi, Weiguo Su, Tienan Yi, Puhan Lu, Panfeng Tan
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Nature
Verified
Cadonilimab plus chemotherapy with or without bevacizumab as first-line treatment for advanced cervical cancer: subgroup analyses from the COMPASSION-16 phase 3 trial
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Abstract The phase 3 COMPASSION-16 trial demonstrates significant progression-free survival (PFS) and overall survival (OS) benefits with cadonilimab plus standard therapy in patients with persistent, recurrent, or metastatic cervical cancer. This analysis aims to assess efficacy outcomes in patient subgroups of COMPASSION-16. The dual primary endpoints of COMPASSION-16 are PFS, assessed by the blinded independent central review (BICR) according to RECIST version 1.1, and OS.
By Yang Sun, Hongying Yang, Jing L. Wang, Dan Li, Ke Wang, Tao Wu, Yuzhi Li, Chunyan Wang, Guiling Li, Yifeng Wang, Dapeng Li, Ying Tang, Mei Pan, Hongyi Cai, Weihu Wang, Hua Qian, Qiuhong Tian, Desheng Yao, Ying Cheng, Bing Wei, Xiumin Li, Tao Wang, Min Hao, Xiaohong Wang, Tiejun Wang, Chang Liu, Hong Zhu, Lijing Zhu, Xianling Liu, Yunxia Li, Lihong Chen, Qingshan Li, Xiaojian Yan, Fei Wang, Hongbing Cai, Yunyan Zhang, Zhiqing Liang, Funan Liu, Yi Huang, Pengpeng Qu, Genhai Zhu, Youguo Chen, Kun Song, Meili Sun, Zhengzheng Chen, Qiang Zhou, Lina Hu, Hongyan Guo, Yijing Ye, Ping Yan, Qiu Tang, Guoping Sun, Ting Liu, Dongmei Lu, Zhongmin Wang, Michelle Xia, Xiaohua Wu, Hanmei Lou, Bairong Xia, Guzhalinuer Abulizi, Sihai Liao, Mingxiu Hu, Baiyong Li
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Nature
Verified
Development and validation of immunotherapy nomogram for predicting the efficacy and prognosis of recurrent and metastatic cervical cancer
Introduction Cervical cancer is the most prevalent gynecological malignancy worldwide and remains one of the leading causes of cancer-related mortality in women (1). While the advent of surgery, concurrent chemoradiotherapy, and intrauterine irradiation has significantly improved the overall response rates and survival outcomes for cervical cancer patients, these treatments have limited efficacy in cases of recurrent or metastatic disease (2).
Visible-Light-Induced Acyl Radical Cascade Cyclization of Dienes with Acyl Chlorides to Synthesize Benzo[b]azepin-2-one Derivatives
Cite Jump to ExpandCollapse ArticleSeptember 12, 2025 Visible-Light-Induced Acyl Radical Cascade Cyclization of Dienes with Acyl Chlorides to Synthesize Benzo[b]azepin-2-one Derivatives Click to copy article linkArticle link copied! Xiangshan Fang Xiangshan Fang School of Chemistry and Chemical Engineering, Yantai University, Yantai 264005, P. R. China Guiling Li Guiling Li School of Chemistry and Chemical Engineering, Yantai University, Yantai 264005, P. R.
Oxidative Cyclization of 1,7‐Dienes Induced by α‐Oxyalkyl/Acyl Radicals to Access Functionalized Benzo[b]azepin‐2‐Ones
Conflict of Interest The authors declare no conflict of interest. Supporting Information Filename Description ejoc202500188-sup-0001-SuppData-S1.pdf5.4 MB Supplementary Material References 1a) , , , , , , , , Eur. J. Med. Chem. 2013, 64, 396; b) , , , , , , , , , , , , , , , Bioorg. Med. Chem. Lett. 2017, 27, 2201; c) , , , , , , , , , , , Cancer Sci. 2020, 111, 279. 2a) , , Eur. J. Org. Chem. 2000, 2000, 3117; b) , , Acc. Chem. Res. 2002, 14, 95. 3a) , , , Chem. Eur. J. 2020, 26, 15354; b) , , , Adv. Synth. Catal.
Oxidative Cyclization of 1,7‐Dienes Induced by α‐Oxyalkyl/Acyl Radicals to Access Functionalized Benzo[b]azepin‐2‐ones
Supporting Information As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors.
Ceramide Ehux-C22 Targets the miR-199a-3p/mTOR Signaling Pathway to Regulate Melanosomal Autophagy in Mouse B16 Cells
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Radical cascade silylation/cyclization of 1,7-dienes to access silyl-substituted benzo[b]azepin-2-ones
Radical cascade silylation/cyclization of 1,7-dienes to access silyl-substituted benzo[b]azepin-2-ones† A novel silyl radical-induced cascade silylation/cyclization of 1,7-dienes has been realized employing readily available hydrosilanes as a silicon source and Cu(I) salt as a catalyst. This protocol introduces diverse silicon fragments into a challenging 7-membered ring structure and provides an efficient approach to a wide array of biologically important silyl-substituted benzo[b]azepin-2-ones.
Identification and Verification of Candidate miRNA Biomarkers with Application to Infection with Emiliania huxleyi Virus
This is an early access version, the complete PDF, HTML, and XML versions will be available soon. Open AccessArticle by , , , and * College of Ocean Food and Biological Engineering, Jimei University, No. 43, Jiyuan Road, Xiamen 361021, China * Author to whom correspondence should be addressed.
The SOX9 Expression Pattern and Its Prognosis in Gastric Cancer Should be Fully Evaluated
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AmpG on AmpC-induced expression in K. pneumoniae.
Back to Journals » Infection and Drug Resistance » Volume 16 Authors Li G, Wang L, Zhang H, Luan Y, Sun Q, Duo L Received 16 May 2023 Accepted for publication 26 July 2023 Published 24 August 2023 Volume 2023:16 Pages 5587—5598 DOI https://doi.org/10.2147/IDR.S421598 Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 2 Editor who approved publication: Professor Suresh Antony Guiling Li,1 Li Wang,2 Heguang Zhang,1 Ying Luan,1 Qi Sun,1 Libo Duo1 1Department...
The Diagnostic Specificity of Blood-Based miRNA Signatures Should be Fully Evaluated
Footnotes # GL and CR contributed equally to the work. Department of Laboratory Medicine, Clinical Medical College of Yangzhou University, Yangzhou, China Department of Clinical Medicine, Yangzhou University, Yangzhou, China
Hemodynamic investigation and in vitro evaluation of a novel mixed flow blood pump
MAIN TEXT Yifei Qu, Yifei Qu Key Laboratory of High Efficiency and Clean Mechanical Manufacture of Ministry of Education, School of Mechanical Engineering, Shandong University, Jinan, P.R. China Key National Demonstration Center for Experimental Mechanical Engineering Education, Shandong University, Jinan, P.R. China Search for more papers by this author Ziyu Guo, Ziyu Guo Key Laboratory of High Efficiency and Clean Mechanical Manufacture of Ministry of Education, School of Mechanical...
Solid Tumor Complicated With Venous Thromboembolism: A 10-Year Retrospective Cross-Sectional Study
Introduction Venous thromboembolism (VTE) is a common complication in the natural history of malignancies. Cancer patients are at a high risk of VTE, account for approximately 20% of all vein thrombosis patients1 and have a 4- to 6-fold increased risk of developing vein thrombosis compared to patients without cancer.
Development and Validation of a Prognostic Nomogram to Guide Decision‐Making for High‐Grade Digestive Neuroendocrine Neoplasms
Introduction Neuroendocrine neoplasms (NENs) are rare malignancies with great heterogeneity 1. Although they are found throughout the body in all organs, approximately three quarters of NENs originate from the gastrointestinal tract and hepato‐biliary‐pancreatic system 2.
Corrigendum to “Role of P2X3 receptor in myocardial ischemia injury and nociceptive sensory transmission” [Auton. Neurosci.: Basic Clin. volume 139, (issues 1-2), (30 May 2008), pages 30-37] - Autonomic Neuroscience: Basic and Clinical
Corrigendum to “Study of baicalin on sympathoexcitation induced bymyocardial ischemia via P2X3 receptor in superior cervical ganglia” [Auton. Neurosci. 189, May 2015, 8–15]
Loss of Cardiolipin Leads to Perturbation of Acetyl-CoA Synthesis
Genome-wide Synthetic Lethal SGA Screen with crd1Δ The genome-wide synthetic lethality screen (31) was performed using SGA methodology by mating the query strain (BY4742 MATα can1Δcrd1Δ) to the yeast deletion set and selecting double mutants at two different temperatures (30 and 37 °C). In the query strain, the crd1Δ mutation was linked to the dominant selectable marker URA3 and the reporter construct MFA1pr-HIS3, which is expressed only in MATa cells.
Loss of Cardiolipin Leads to Perturbation of Acetyl-CoA Synthesis
Cardiolipin (CL), the signature phospholipid of mitochondrial membranes, plays an important role in mitochondrial processes and bioenergetics. CL is synthesized de novo and undergoes remodeling in the mitochondrial membranes. Perturbation of CL remodeling leads to the rare X-linked genetic disorder Barth syndrome, which shows disparities in clinical presentation.
Loss of cardiolipin leads to perturbation of acetyl-CoA synthesis
Cardiolipin (CL), the signature phospholipid of mitochondrial membranes, plays an important role in mitochondrial processes and bioenergetics. CL is synthesized de novo and undergoes remodeling in the mitochondrial membranes. Perturbation of CL remodeling leads to the rare X-linked genetic disorder Barth syndrome (BTHS), which shows disparities in clinical presentation.
Nature Communications
To examine whether BARS interacts with an LPAAT, we first sought to identify the LPAATs that localize to the Golgi, as most of the BARS-dependent fission reactions occur in this organelle15, 16. We Flag-tagged and expressed the available mammalian LPAATs and inspected their localization by immunofluorescence microscopy. LPAATγ, LPAATδ and LPAATη localized to both the Golgi and the endoplasmic reticulum (ER) (Fig.
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