Imran MOhammad
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Articles by Imran MOhammad
The Maternal-Infant Microbiome Continuum: From Pregnancy Programming to Lifelong Health
Submitted: 15 September 2026 Posted: 17 September 2026 You are already at the latest version Background: The maternal microbiome represents the first microbial environment for the developing infant, with emerging evidence linking maternal dysbiosis to adverse pregnancy outcomes and lifelong offspring health.
Surfaceome CRISPR activation screening uncovers ligands regulating tumor sensitivity to NK cell killing
Abstract Natural killer (NK) cell-based immunotherapies are promising for cancer treatment due to their ability to eliminate cancer cells independently of antigen presentation and “off-the-shelf” utility. However, molecular determinants governing tumor susceptibility to NK cytotoxicity remain incompletely understood. Here we employ CRISPR activation (CRISPRa) screening to identify cancer cell surface regulators of NK killing.
CD39 + CD49a + CD103 + cytotoxic tissue-resident natural killer cells infiltrate and control solid epithelial tumor growth in mice
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Editor’s summary Natural killer (NK) cell–based therapies for cancer have shown promise; however, there remains the need to identify the most effective antitumor NK cell subpopulation. Here, Horowitz et al. identified a population of tissue-resident, cytotoxic CD49a+CD103+ NK cells that were distinguishable from their more immunosuppressive counterparts by coexpression of CD39.
By Alka Khaitan, David R. Ziehr, PING LIU, Nina Horowitz, Imran MOhammad, June Ho Shin, John Hickey Verified, Peter J. Chockley, Gail Snyder, CHEN CHEN, Keene Lee, Krishna Sharma Verified, Quan Tran, Anahita Nejatfard, Sainiteesh Maddineni, Vasu Divi, Catherine A. Blish, Garry P. Nolan, Jennifer A Foltz, John Sunwoo
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Science Magazine
Verified
Unveiling the Synapses: Gut Microbiota and Neurodegenerative Disorders Through the Gut-Brain Axis
Submitted: 07 December 2025 You are already at the latest version The microbiota–gut–brain axis (GBA) is a bidirectional communication system integrating neural, endocrine, immune, and metabolic pathways to coordinate gastrointestinal and central nervous system (CNS) function. As the majority of human microbes reside in the gastrointestinal tract, their metabolic activity and immunomodulatory roles are essential for systemic homeostasis, cognitive processes, mood regulation, and neuroprotection.
Beyond Digestion: The Gut Microbiota as an Immune-Metabolic Interface in Disease Modulation
Submitted: 15 September 2025 Posted: 16 September 2025 You are already at the latest version The gut microbiota has emerged as a critical immune-metabolic interface, orchestrating a complex network of interactions that extend well beyond digestion. This highly diverse community of bacteria, viruses, archaea, and eukaryotic microbes modulates host immunometabolism, metabolic reprogramming, and systemic inflammatory responses, thereby shaping human health and disease trajectories.
H5N1 to H7N9: Assessing the Global Impact and Preparedness for 2025
This version is not peer-reviewed. This version is not peer-reviewed. Highly Pathogenic Avian Influenza (HPAI) viruses, particularly H5N1, continue to pose a major global threat due to their widespread circulation and high mortality rates in birds. Management of HPAI is complicated by challenges in conserving migratory bird populations, sustaining poultry production, and uncertainties in disease dynamics.
Enhancing Food Safety: Adapting to Microbial Responses Under Diverse Environmental Stressors
You are already at the latest version This comprehensive review explores the critical role of microbial adaptation in enhancing food safety by responding to diverse environmental stressors—an essential aspect of microbial ecology with profound implications for biotechnology, environmental management, and public health.
The Impact of Healthcare Simulation on Practical Training: Enhancing Medical Students’ Proficiency in In-Vitro Male by Catheterization Procedures
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389 Ex vivo expanded ieILC1-like NK cells induce significant tumor cell death and demonstrate metabolic flexibility and macrophage reprogramming capacity under hypoxic conditions | Journal for ImmunoTherapy of Cancer
http://creativecommons.org/licenses/by-nc/4.0/ This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial.
Pharmacological effects and mechanisms of paeonol on antitumor and prevention of side effects of cancer therapy
1 Introduction In recent times, the global incidence and mortality rates of cancer have exhibited a rapid upsurge, owing to several factors, including the progress of human society, economic development, and other multifarious factors. According to data, cancer is currently the second leading cause of death globally, following ischemic heart disease, and is projected to become the primary cause of death by 2060 (Bray et al., 2018; Mattiuzzi and Lippi, 2019).
Afghanistan: Taliban torture and execute Hazaras in targeted attack
16 September 2022 Six people killed during a night raid on a family home in Ghor province, including a 12-year-old girl Ongoing Taliban killings indicate a pattern of attacks on ethnic minorities and members of the former security forces Taliban fighters killed six Hazara people in a deliberate attack on the ethnic minority group in Afghanistan’s Ghor province, Amnesty International said today following a new investigation.
INTERNATIONAL JOURNAL OF CIVIL ENGINEERING AND TECHNOLOGY (IJCIET) © IAEME Publication | https://iaeme.com/Home/journal/IJCIET
Articles Archive Subject Area Indexing Aims & Scope Editorial Board For Authors Publication Fees 1 Civil Engineering Department, Faculty of Engineering, Universitas Indonesia, Depok, Indonesia. 2 Civil Engineering Department, Faculty of Engineering, Universitas Padjadjaran, Depok, Indonesia. 3 Department of Geophysics, Faculty of Mathematics and Natural Sciences, Universitas Padjadjaran, Sumedang, Indonesia.
Life in Chicago for former Manus detainee
Life for me has changed immensely since I received my freedom in the United States. I have learnt so much in such a short time. I used to think there was an end point to learning, but we never stop. There are so many stages in life and each teaches us something new and different. In America, I have finally found a place to call home and a country of which I can be a part. It has been a little over six months since I arrived in Chicago from Manus Island, via Los Angeles.
‘I am Imran’
I never thought I would hold a piece of paper that said I was a recognised citizen of any country. But now, after seven years’ imprisonment in refugee detention, I am no longer known by my boat ID EMP-065. I am Imran. I can’t find the exact words to describe the feeling of being free. I live in Chicago now, in the most diverse neighbourhood, crowded with many people of different nationalities. My home is on the second floor of an apartment block.
Estrogen receptor α contributes to T cell-mediated autoimmune inflammation by promoting T cell activation and proliferation
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What's NXT without Nick Xenophon?
Last Monday, it was clear Nick Xenophon was itching to get out of the place. He sat in his first-floor office on the senate side of Parliament House surrounded by cardboard boxes stuffed full of documents and belongings. He had decided long before the High Court eligibility case to cut short his newly won six-year term and take the political gamble of his life back in South Australian state politics.
Closing Manus Island
The refugees and asylum seekers on Manus Island are at the lowest point of their lives. There are no words to describe the pressure the Australian government is imposing in order to empty and close its illegal offshore detention centre by October 31. The way in which the Australian government is managing the impending closure of the centre is making a bad situation worse.
Four years on Manus Island
Australia’s prison camp on Manus Island has snatched four years from our lives. July 19, 2013 is the date on which our world was torn apart. It is impossible to describe everything that we have been through over the past four years. I was only 19 years old when I arrived and had no idea how I would survive in this gruesome, inhumane setting. I fell in love with writing, which has meant my survival over these four years.
Her own league: Maddie Studdon, 22, rugby league player
I started when I was young – I grew up playing with the boys, up to 12 years old. Then I had to stop. When I hit 16 there wasn’t much girls’ football happening, but in the last probably three to four years it’s picked up. Especially after the past year. It is growing, and there’s more pathways coming along now. The young girls have a way to come through all the representative stages. The ladies who played before us, they paved the way and they did it the hard way.
Tubelight movie review: Salman Khan plays a vulnerable role for the first time, and aces it
In the trailer for Tubelight, Salman is seen to be a simpleton (yet again after Bajrangi..) and is a happy-go-lucky guy, who is close to his brother Bharat (Sohail Khan). His world sort of falls apart when Sohail, as part of the Army, has to go away, and doesn't return. Laxman (Salman), called Tubelight lovingly by the kids in his neighborhood, vows to find his brother at any cost. What we see over the film, will be his journey — good, bad and ugly.
What I Learned About Love and Writing in Refugee Detention
Born in Myanmar, Imran Mohammad faced persecution as a member of the Rohingya minority and took perilous boat journeys to Malaysia and Indonesia as a teenager. Facing continued dangers and an uncertain future, he eventually tried to reach Australia by boat. Australia intercepts refugee and migrant boats and prevents their passengers from ever settling in the country, instead sending them to offshore detention centers it operates on Papua New Guinea and Nauru.
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