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Articles by Jack Brown
'Clean your plate' | Opinion
Construction crews begin work on a new sidewalk connection in the neighborhood. Columnist Jack Brown said the project was made possible through the persistence of local leaders and a commitment to community safety. "Clean your plate." Most of us heard those words growing up. Parents and grandparents used them at the dinner table as a reminder to finish what was in front of us before moving on.
The George-Anne Media Group
Categories: November 3, 2026 About the Contributors Jack Brown, Lead Photographer, George-Anne Daily Jack is a sophomore Mechanical Engineering major from Jacksonville, Fl. This is his first year as Lead Photographer, and he enjoys photography, being in the gym, playing video games, and hanging out with friends. Jace is a freshman Multimedia Film Production major from Newnan, Georgia. This is his first year as a Per Diem Photographer.
TMPRSS2-mediated coronavirus spike activation and inhibition
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Abstract The protease TMPRSS2 facilitates coronavirus infections, yet its mechanism of viral glycoprotein recognition remains unclear. Here we show that, following ACE2 engagement of the SARS-CoV-2 spike (S) inducing the early fusion intermediate conformation (E-FIC), TMPRSS2 cleaves the R815 S2′ site and promotes fusogenic conformational changes leading to viral entry.
By Matthew McCallum Verified, James Case, Jack Brown, Young-Jun Park, Jimin Lee, Emmajay Sutherland, Anupriya Aggarwal, Cecily Gibson, Florian A. Lempp, Cameron Stewart Verified, M. Alejandra Tortorici, Jun Siong Low, Daniel Asarnow, Dana Bohan, Exequiel Dellota Jr, Bhavna Chawla, Swagata Kar, Antonio Lanzavecchia, Federica Sallusto, Nicholas Riley, Stuart Turville, Lisa A. Purcell, Michael Diamond Verified, David Veesler, Shilpa Sanapala, Benjamin Merz
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Nature
Verified
2025 was a year of science breakthroughs
As the new year begins, it's a good time to look back on some of the major breakthroughs in science and to consider what the future may hold. In 2025, artificial intelligence made major leaps across many fields, gene-editing technologies moved into real human use, and both mRNA technology and monoclonal antibodies continued their rapid progress.
Functional and antigenic landscape of the Nipah virus receptor-binding protein
ArticleOnline nowOpen access 1Basic Sciences Division and Computational Biology Program, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA 2Department of Biochemistry, University of Washington, Seattle, WA 98195, USA 3Department of Pathology Microbiology and Immunology, The Vanderbilt Vaccine Center, and Department of Pediatrics, Vanderbilt University Medical Center, Nashville, TN 37232, USA 4Howard Hughes Medical Institute, Seattle, WA 98195, USA Publication History: Received May 8,...
“Frío amenazante para la vida” afecta a partes de EEUU tras inundaciones mortales del fin de semana
BISMARCK, Dakota del Norte, EE.UU. (AP) — Un frío intenso descendió el lunes sobre la parte central de Estados Unidos, mientras un vórtice polar afectaba las Montañas Rocosas y las llanuras del norte tras las tormentas del fin de semana que azotaron el este del país con inundaciones, causando la muerte de al menos 14 personas.
Protein nanoparticle vaccines induce potent neutralizing antibody responses against MERS-CoV
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Keywords MERS-CoV EMPEM nanoparticle vaccine RBD NTD spike Research topic(s) CP: Immunology Introduction The recent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has demonstrated the human and economic toll that can accompany the spillover and spread of a zoonotic disease in humans.
By Kaitlin R Sprouse, Marcos Miranda, Nicholas J. Catanzaro, Amin Addetia, Cameron Stewart Verified, Jack Brown, Annie M. Dosey, Adian Valdez, Rashmi Ravichandran, Maggie Ahlrichs, Craig L. Dobbins, Alexis Hand, Catherine Treichel, Alexandra C. Walls, Andrew McGuire, Elizabeth M. Leaf, Ralph S Baric, Alexandra Schafer, David Veesler, Neil King, Cara W. Chao, Miranda L. Hubbard, Grace G. Hendricks, Jackson McGowan, Isabelle Willoughby
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Cell Reports
Verified
9 Benefits of Natural or Handmade Soaps
Natural or handmade soaps are made through traditional soapmaking methods and often use plant-based oils, butters, and minimal processing. The primary appeal is a combination of ingredient transparency, preserved glycerin, and the absence of many synthetic detergents and preservatives commonly found in mass-market bars and body washes. Quick summary Gentler cleansing and retained glycerin help moisturize skin. Fewer synthetic additives can reduce exposure to some irritants.
Alcohol use during pregnancy
Hello all, I am Grace. I am looking for some suggestions. I am 3 months pregnant now, and I have a small drinking problem. I am worried if this will affect the health of my baby. I am trying hard to stop drinking, but it's difficult for me. My husband is suggesting to get help from a rehab. We even took an appointment at a recovery center called Freedom from addiction. But the thing is that I don't know if it's the right thing to do at this stage.
Crossing The Line. What’s It All About?
Our Crew 2 Crew blog is back, written by Captain Jack Brown. This time, Jack is taking you through the Crossing The Line ceremony and what it means for crew! For centuries, sailors have crossed the oceans, braving the elements and trying to tame the seas, among the many maritime traditions that have withstood the test of time is the ‘Crossing the Line’ ceremony. This historical ritual marks the moment a ship crosses the equator and is a rite of passage for all seafarers lucky enough to sail there.
Persistent immune imprinting occurs after vaccination with the COVID-19 XBB.1.5 mRNA booster in humans
Highlights • XBB.1.5 COVID-19 mRNA vaccine elicits neutralizing antibodies against current variants • Depletion of Wuhan-Hu-1 S-reactive plasma antibodies abrogate XBB.1.5 neutralization • XBB.1.5 COVID-19 mRNA vaccine primary recalls Wuhan-Hu-1 S-reactive memory B cells Summary Immune imprinting describes how the first exposure to a virus shapes immunological outcomes of subsequent exposures to antigenically related strains.
Persistent immune imprinting occurs after vaccination with the COVID-19 XBB.1.5 mRNA booster in humans
Highlights • XBB.1.5 COVID-19 mRNA vaccine elicits neutralizing antibodies against current variants • Depletion of Wuhan-Hu-1 S-reactive plasma antibodies abrogate XBB.1.5 neutralization • XBB.1.5 COVID-19 mRNA vaccine primary recalls Wuhan-Hu-1 S-reactive memory B cells Summary Immune imprinting describes how the first exposure to a virus shapes immunological outcomes of subsequent exposures to antigenically related strains.
Helping Your Kids Manage Their Asthma Symptoms
Summary Learn to manage your child's asthma symptoms by understanding triggers, medication adherence, and creating a supportive environment for better health. Press Release Manchester, [7 march 2024] – Managing your child’s asthma symptoms can be tough for parents. It may appear like keeping an eye out for potential triggers and checking their medication is a losing battle.
Tiny Lungs, Big Care: Manchester's Best Baby Cough Doctor
Summary Proudly introducing Dr. Anirban Maitra, renowned as the best baby cough doctor in Manchester, this seasoned professional is dedicated to providing top-notch care for the tiniest members of our community. Press Release For Immediate Release: Manchester, [29. January 2024] – When it comes to the health and well-being of our little ones, finding the right medical care is paramount.
Jack Brown: Lessons for devolution from the Covid inquiry hearings
Three of England's big city Mayors gave evidence last week and some common frustrations with central government emerged It was “Mayors day” at the Covid-19 Inquiry last week. Sadiq Khan, Mayor of Greater Manchester Andy Burnham and Mayor of the Liverpool City Region Steve Rotherham gave evidence about their experiences during the pandemic. Not many appear to have been positive. I watched Mayor Khan’s and Mayor Burnham’s testimonies.
Jack Ryan Brown
Ashley Adams and Shawn Brown welcomed their new baby boy, Jack Ryan Brown, into the world at 7:24 p.m. September 16, 2023. Jack Ryan Brown weighed 10 pounds 3 ounces and was 23 inches. Jack Ryan joins his siblings McKenzie, Catricia, Grace, Brooklyn, Kamrynn and Bayli. Maternal grandparent is Kathryn Comstock. Paternal grandparents are Kim Brown and Betty Brown. Paternal greatgrandparents… Premium Content is available to subscribers only.
Crawford vs. Spence: Lopsided bout unifies welterweight title
BY JACK BROWN | On Saturday night July 29, Houston Hall provided a welcome relief from the New York City heat wave. The occasion was Terence “Bud” Crawford versus Errol “The Truth” Spence on the big screen for the undisputed welterweight championship of the world. All the belts. When Bud Crawford emerged from the dressing room for the Vegas bout he was in beast mode. A menacing, malevolent presence in black. A creature from the deep or a gladiator from a Roman arena.
Evil Days And Evil Ways: Flash Fiction By Jack Brown
Jack Brown, author of “Evil Days And Evil Ways” is an author and poet who lives and works in New York City. Those were wild and unruly days. Followed by hollow sleepless nights. They did most everything together. Ate together-if they ate. Slept together-when they slept. Drank together and drove his Impala around the back roads of that Northern California mountain town like he was back home in New York. Riding the Cyclone roller coaster on Coney Island.
Poem: McSorley's is McSorley's - The Village Sun
BY LINCOLN ANDERSON | Updated Dec. 12, 6 p.m.: While the historic, one-day union walkout strike at The New York Times this past Friday riveted... BY LINCOLN ANDERSON | George Capsis had just been asked how he felt about a new newspaper, the New WestView News, having been published by... BY LINCOLN ANDERSON | Drama, intrigue, conspiracy theories galore, alleged backstabbing... . No, it’s not the latest Netflix or HBO series about badly behaving royals...
4 Best Bedtime Fabrics for Toddlers
When it comes to making kid's clothing, the possibilities are endless. From snaps to zippers, buttons to ties, and everything in between, there are a million ways you can design kid's clothing. Many factors go into choosing suitable fabrics for any project, but when working with kids' bedtime clothing, you have even more considerations. Durability is key; you want to select materials that stand up against any issues when babies are napping. Here are the four best bedtime fabrics for your toddler. 1.
Hey Pandas, What Are Some Things You Do To Stop Boredom On Long Flights?
What are some things you do to stop yourself from getting bored on long flights? #1 Read, adult coloring, games, movies, Report #2 Offline games, read books, listen to music, watch movies in my head that I have memorized, sleep Report #3 Looking at the flight map and improving my geography skills Report #4 Break up the time in weird but better-sounding increments. An eight-hour flight is still under 10 hours. It's 2 x 4 hours, and 4 hours are ok to pass.
Letter to the Editor: Keep Train Option
Thank you for the “Growing Pains” article (GT, 8/25). Great reporting. Showed many takes on what is at stake. Greenway is an organization that promotes removing the rails from the train right of way. I heard that the financial backing comes from some big ag interests. They stand to gain acreage from the right of way along ag land in Watsonville area if trains no longer use it. My supervisor, Manu Koenig, was strongly connected to Greenway before he ran for office.
On 9/11, East River Park was a refuge
BY JACK BROWN | The morning of that 9/11 I was walking a little dog on Seventh Street. The dog liked to visit an Asian laundry. I used to weigh her on the scale. She liked the woman who worked there. The woman said, “Plane hit World Trade tower.” I asked, “Big plane or small plane?” “Small plane,” she said. We kept walking. Around the corner on Sixth Street a neighbor was in a panic. “Two planes hit the World Trade towers,” he told me.
BTS’s Jungkook tells Stephen Colbert on The Late Show that he invented Star Trek’s Vulcan salute — Daily Star Trek News
MAY 27, 2021 - For years the Vulcan hand salute has been part of the DNA of the Star Trek universe, and now, thanks to K-Pop phenomenon BTS and The Late Show with Stephen Colbert, one of the most beautiful moments in the life of our beloved franchise may have a new origin story.
My Turn: There’s too much hate in Gaston County
By Jack Brown Tuesday Jul 14, 2020 at 2:31 PM Having lived in Gaston County all my life with the exception of my service in the United States Army, I retired from work in 1997 and have devoted most of my time to public service. As many say after leaving their lifetime careers, I was determined to never truly retire — I simply shifted much of my day-to-day time investments to other meaningful endeavors.
London's Mayor at 20
Find out more about what went into writing London's Mayor at 20 in an exclusive blog written by Jack Brown for the Biteback website. A few months into the new millennium in May 2000, Ken Livingstone became the first ever Mayor of London. In the succeeding two decades, London has undergone a dramatic evolution under three very different mayors, but how has the mayoralty itself changed? How have the capital’s challenges and crises been overcome? And is the office still fit for purpose?
Home Movies
As we all navigate our way through this new landscape of isolation and social distancing, most of us have lost the small local connections we once took for granted. The familiar hello of a barista who poured our morning coffee, the nod of the bus driver who brought us to work, the thousands of quick conversations had across retail counters everyday. But if that absence has left an emptiness in us, it’s also been felt — even more keenly — by the businesses affected by the crisis.
Alone Together
I don’t know about the rest of you, but I’m starting to miss the world. Out of work and holed up in the house — half the week in a kind of monkish solitude, the other half with three increasingly stir-crazy kids — is exactly the opposite of what anyone wants out of spring in New England. But if it’s been trying, it at least coincided with a stretch of damp and chilly days that made never taking my pajamas off seem somewhat reasonable.
Cinemadope: Home Theater
It might seem silly to have a local film column this week. As I write, public schools are shutting down for a three-week hiatus, restaurants are shifting strictly to takeout service, and we’re all avoiding crowds. The long-running Pioneer Valley Jewish Film Festival is being postponed. Amherst Cinema is closed, as is the Latchis in Brattleboro and the mall megaplex Cinemark.
Cinemadope: Dog days - Killy Reichardt returns
Published: 3/13/2020 10:40:10 AM Modified: 3/13/2020 10:39:55 AM “All it takes is one bad day,” a famous cartoon villain once said, “to reduce the sanest man alive to lunacy.” And while Kelly Reichardt’s 2008 film “Wendy and Lucy” is about as far as one can get from the world of the Dark Knight, it takes that “one bad day” idea and turns it into something far more real and affecting. There will be no Wendy Halloween costumes, come October.
Dog Days
“All it takes is one bad day,” a famous cartoon villain once said, “to reduce the sanest man alive to lunacy.” And while Kelly Reichardt’s 2008 film Wendy and Lucy is about as far as one can get from the world of the Dark Knight, it takes that “one bad day” idea and turns it into something far more real and affecting. There will be no Wendy Halloween costumes, come October.
BOARD GAMING in Danvers!
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Cinemadope: Toon in - Animation for the late-night crowd
Published: 2/28/2020 9:44:16 AM In the run-up to the Oscars a few weeks ago, you might have seen a flurry of activity from local theaters as they featured the yearly roundup of animated short films that were vying for the golden statuette. It’s always a treat to see that collection of film on the big screen, and in front of so many eyeballs that would almost certainly not see them otherwise.
Cinemadope: Toon in - animation for the late-night crowd
In the run-up to the Oscars a few weeks ago, you might have seen a flurry of activity from local theaters as they featured the yearly roundup of animated short films that were vying for the golden statuette. It’s always a treat to see that collection of film on the big screen, and in front of so many eyeballs that would almost certainly not see them otherwise.
We need political courage on homelessness and recidivism
CORE DC Chairman and Chief Executive Jack Brown by Jack Brown TriceEdneyWire.com – With the Democratic primary kicking into gear and the general election right around the corner, the stage is set for an impassioned battle of ideas and policy initiatives that could shape our country for the next decade.
We Need Political Courage on Homelessness and Recidivism
We Need Political Courage on Homelessness and Recidivism Feb 19, 2020Editorial By Jack Brown (TriceEdneyWire.com) – With the Democratic primary kicking into gear and the general election right around the corner, the stage is set for an impassioned battle of ideas and policy initiatives that could shape our country for the next decade.
Cinemadope: A vacation-week film festival in Northampton
Published: 2/14/2020 10:29:21 AM Modified: 2/14/2020 10:29:09 AM I still remember that day, bright with promise, just after the new year had dawned, when my children finally had to go to school again. Don’t get me wrong, I love the little scamps more than I’ve ever loved anything on this earth, but two weeks of holidays, sugar, and interstate travel take a toll. And now, just as we’ve found our groove again, comes February break.
Cinemadope: Screen Time
I still remember that day, bright with promise, just after the new year had dawned, when my children finally had to go to school again. Don’t get me wrong, I love the little scamps more than I’ve ever loved anything on this earth, but two weeks of holidays, sugar, and interstate travel take a toll. And now, just as we’ve found our groove again, comes February break.
Torch Song
Waiting is hard. Some of us skip ahead in our books, others sneak a peek at a bride before the ceremony. Some of us roar past a minivan going a perfectly reasonable 70 mph on 91 South — I’m looking at you, white Honda Civic. There’s just something about getting an early look that seems hardwired into us humans. If that sounds familiar, then this is your week.
Mean Green tennis has best start in history against Northwestern State
Saturday evening’s win 5-2 against Northwestern State marks the best start in Mean Green tennis history at 4-0. They have taken 24 out of the possible 28 points against opponents and are 3-0 against Southland Conference opponents. Saturday’s win also came on UNT’s first of many cultural day matches, which means Mean Green tennis honors every player’s home country throughout the spring season. Today was China in honor of freshmen Kexuan Zhou from Changsha, China.
We need political courage on homelessness and recidivism
By Jack Brown TriceEdneyWire.com With the Democratic primary kicking into gear and the general election right around the corner, the stage is set for an impassioned battle of ideas and policy initiatives that could shape our country for the next decade. Fortunately, sitting lawmakers and candidates from both sides of the aisle have shown a willingness to take on some of the greatest challenges of our time – from health care and the economy to education and foreign policy.
The Short List
Ever since I was first introduced to the tiny hot dog, I have been an appetizer man. Those delectable little morsels — a bite or two at most — can contain a density of flavor that many full meals can only wish to attain. And while many are served ahead of an ostensibly heartier “main” course, I could (and, to be honest, often do) make a full dinner out of those richly delicious small bites. Keep your meat and potatoes, give me Roquefort popovers and stuffed mushrooms.
Recap: Mean Green tennis turns the page on Lamar, tallies third straight victory
The Mean Green tennis team (3-0) dialed up a 6-1 score against Lamar (0-2), which marks North Texas’ 10th straight win against the Cardinals. The last time that Mean Green tennis started 3-0 was 15 years ago back in 2005. This year’s roster features one of the younger teams in Texas. Doubles played early Sunday evening had the same results as the past two weeks, all three doubles pairs came out with the win.
We Need Political Courage on Homelessness and Recidivism
By Jack Brown (TriceEdneyWire.com) – With the Democratic primary kicking into gear and the general election right around the corner, the stage is set for an impassioned battle of ideas and policy initiatives that could shape our country for the next decade. Fortunately, sitting lawmakers and candidates from both sides of the aisle have shown a willingness to take on some of the greatest challenges of our time – from health care and the economy to education and foreign policy.
Cinemadope: Guy Ritchie returns to crime with The Gentlemen
There was a time, once, when British director Guy Ritchie was considered the across-the-pond reflection of Quentin Tarantino. The filmmaker who, four years after Tarantino’s Pulp Fiction and six after Reservoir Dogs, started pumping out stylish if patchy tales centered on the low end of the British criminal class: guys who cheat at cards and pay to get fights thrown, but whose station remains the same, however rich they might hope to become.
Movies: ‘Invisible Hands’ shows the hidden cost of everyday things
Published: 1/17/2020 9:40:04 AM Modified: 1/17/2020 9:39:10 AM Ask most Americans when slavery ended, and you’ll likely hear something about the Civil War and Abe Lincoln. Ask them about the rest of the world, and you may be met by a blank stare. But the truth is that it continues on in our modern era, and that many of us, without knowing it, are the end users of the products that are the result of a long chain of child labor.
Child’s Work
Ask most Americans when slavery ended, and you’ll likely hear something about the Civil War and Abe Lincoln. Ask them about the rest of the world, and you may be met by a blank stare. But the truth is that it continues on in our modern era, and that many of us, without knowing it, are the end users of the products that are the result of a long chain of child labor.
Inside Number 10
Jack Brown showcases hidden heroes, the history of the building and the famous figures who have passed through The shrewdest advice I was given on becoming Political Secretary to the Prime Minister in 2016, by a former habitué of Downing Street, was to ‘go for a wander occasionally to see what’s happening elsewhere in the building’.
Cinemadope: A Developing Story - the invention of a camera for the masses
Like most everyone with kids these days, I tried my best to capture a bit of the holiday magic this season. Photos, videos, the occasional audio recording — moments to share with far flung family who wouldn’t get to see Christmas morning, and memories to share with my kids when they themselves are older. It’s a big difference from my own childhood.
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