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Jaskirat Singh

As seen in: Medium, Nature, arXiv, ScienceDirect, Sap Blogs, DEV Community, The Wire (India), Dialnet - Universidad de La Rioja, Mondaq, Medianama and
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Articles

Author Correction: Casdatifan shows durable response linked to HIF-2α biology in kidney cancer

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By Toni K. Choueiri, Jaime R. Merchan, Amita Patnaik, Alexandra Drakaki, Brian Rini Verified, Sun Young Rha, Jae Lee, Moshe C. Ornstein, Rohit Kumar, Clara Hwang, Yusra Shao, Pedro Barata, Bradley A McGregor, Paul Foster, Jianfen Chen, Melissa Eisen, Hunter Cole, Ben Weeder, Yinghui Guan, Jaskirat Singh, Angelo Kaplan, Soonweng Cho, Richard Markus, Omar Kabbarah, Rana R. McKay
| Nature Verified
Correction to: Nature https://doi.org/10.1038/s41586-026-10718-x Published online 1 July 2026 In the version of this article initially published, the name of Jaime Merchán was misspelled (Jamie Merchan) and is now amended in the HTML and PDF versions of the article.
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Casdatifan shows durable response linked to HIF-2α biology in kidney cancer

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By Toni K. Choueiri, Amita Patnaik, Alexandra Drakaki, Brian Rini Verified, Sun Young Rha, Jae Lee, Moshe C. Ornstein, Rohit Kumar, Clara Hwang, Pedro Barata, Bradley A McGregor, Paul Foster Verified, Jianfen Chen, Melissa Eisen, Hunter Cole, Ben Weeder, Yinghui Guan, Jaskirat Singh, Angelo Kaplan, Soonweng Cho, Richard Markus, Omar Kabbarah, Rana R. McKay, Jamie Merchan, Yusra Shao
| Nature Verified
Abstract Clear cell renal cell carcinoma (ccRCC) is largely driven by the transcription factor hypoxia-inducible factor 2α (HIF-2α)1. Here we show that monotherapy with casdatifan—an orally bioavailable, potent and selective HIF-2α inhibitor2—produces meaningful, durable antitumour activity with manageable safety in individuals with refractory metastatic ccRCC.
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If Your Code Works on the First Try, There’s a Massive Mistake Somewhere

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By Jaskirat Singh
| DEV Community
I read this line somewhere on Reddit and it stuck with me: If your code works on the first try, there is a massive mistake somewhere. It sounds like a joke, but every experienced developer knows there’s a painful truth hidden inside it. TL;DR When code works on the first run, it usually means you tested only the happy path. Missing edge cases, untested assumptions, environment mismatches, or silent failures are often hiding underneath. First-try success should trigger skepticism, not celebration.
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