Joscha Griger on Muck Rack

Joscha Griger

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Articles

A disease model resource reveals core principles of tissue-specific cancer evolution

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By Sebastian P. Mueller, Markus Tschurtschenthaler, Miguel Silva, Riccardo Trozzo, Thorsten Kaltenbacher, Magdalena Zukowska, Daniele Lucarelli, Rupert Öllinger, Nina Lucia Groß, Tanja Groll, Jeroen M. Bugter, Stefanie Barthel, Chiara Falcomatà, Alexander Strong, Aristeidis Papargyriou, Roman Maresch, David Sailer, Christian Schneeweis, Lisa Frohlich, Christine Klement, Juan Montero Verified, Ute Jungwirth, Maximilian Reichert, Markus Moser, Jens Neumann, George S. Vassiliou, Juan Enrique Cadiñanos, Ignacio Varela Verified, Carsten Marr, Daniel F. Alonso, Pier-Luigi Lollini, Jean J. Zhao, Louis Chesler, Clare M. Isacke, Angela Riedel, Christian J. Braun, Martin L. Sos, Filippo Beleggia, Hans Reinhardt, Monica Musteanu, Mariano Barbacid, Michael Quante, Marc Schmidt-Supprian, Günter Schneider, Simon Clare, Trevor D. Lawley, Gordon Dougan, Katja Steiger, Nathalie Conte, Allan Bradley, Dieter Saur, Roland Rad, Niklas de Andrade Krätzig, Chiara Thordsen, Perrine Simon, Frederic Saab, Joscha Griger, Jessica Löprich, Antonio E. Zaurito, Linus R. Schömig, Cordelia Brandt, Mulham Najajreh, Katharina A. N. Collins, Sebastian Burger, Alexander Belka, Lena Rad
| Nature Verified
Abstract Oncogenes such as KRAS display marked tissue specificity in their oncogenic potential, genetic interactions and phenotypic effects, but the underlying determinants remain largely unresolved1,2,3,4,5. Here, to address these questions, we developed the Mouse Cancer Cell line Atlas, a broad-utility resource of 590 comprehensively characterized models across a wide range of entities (www.mcca.tum.de).
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