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Gordon Dougan

Cambridge University
As seen in: Nature, The Conversation, Agenda (World Economic Forum), Medical Xpress, Cell Press, The Lancet, Scroll.in, eLife, JoVE- Journal of Visualized Experiments, Microbiology Research and
Professor in Medicine Department, University of Cambridge. Awarded 2020 Albert Sabin Gold Medal for work on affordable vaccines. Supports Scunthorpe United
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Articles

Pulmonary inflammation in severe pneumonia is characterised by compartmentalised and mechanistically distinct sub-phenotypes

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By Mark Jeffrey, Josefin Bartholdson Scott, Richard White, Ellen Higginson, Mailis Maes, Sally Forrest, Joana Pereira-Dias, Surendra Parmar, Martin D. Curran, Petra Polgarova, Jurgen Herre, Els Wauters, Diether Lambrechts, Pierre Van Mol, Cato Jacobs, Joost Wauters, Emma Davenport, Stephen Baker, Gordon Dougan, Vilas Navapurkar, Andrew Morris, Shyamanova Mazumdar, Emma Heasman-Hunt
| Nature Verified
Abstract Pneumonia is the leading infectious disease killer worldwide and commonly requires admission to critical care. Despite its prevalence, the underpinning biology of severe pneumonia remains incompletely understood. Here we perform multifaceted assessments of bronchoalveolar transcriptome, cytokines, microbiology, and clinical features to biologically characterise a cohort of patients with suspected severe pneumonia.
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A disease model resource reveals core principles of tissue-specific cancer evolution

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By Sebastian P. Mueller, Markus Tschurtschenthaler, Miguel Silva, Riccardo Trozzo, Thorsten Kaltenbacher, Magdalena Zukowska, Daniele Lucarelli, Rupert Öllinger, Nina Lucia Groß, Tanja Groll, Jeroen M. Bugter, Stefanie Barthel, Chiara Falcomatà, Alexander Strong, Aristeidis Papargyriou, Roman Maresch, David Sailer, Christian Schneeweis, Lisa Frohlich, Christine Klement, Juan Montero Verified, Ute Jungwirth, Maximilian Reichert, Markus Moser, Jens Neumann, George S. Vassiliou, Juan Enrique Cadiñanos, Ignacio Varela Verified, Carsten Marr, Daniel F. Alonso, Pier-Luigi Lollini, Jean J. Zhao, Louis Chesler, Clare M. Isacke, Angela Riedel, Christian J. Braun, Martin L. Sos, Filippo Beleggia, Hans Reinhardt, Monica Musteanu, Mariano Barbacid, Michael Quante, Marc Schmidt-Supprian, Günter Schneider, Simon Clare, Trevor D. Lawley, Gordon Dougan, Katja Steiger, Nathalie Conte, Allan Bradley, Dieter Saur, Roland Rad, Niklas de Andrade Krätzig, Chiara Thordsen, Perrine Simon, Frederic Saab, Joscha Griger, Jessica Löprich, Antonio E. Zaurito, Linus R. Schömig, Cordelia Brandt, Mulham Najajreh, Katharina A. N. Collins, Sebastian Burger, Alexander Belka, Lena Rad
| Nature Verified
Abstract Oncogenes such as KRAS display marked tissue specificity in their oncogenic potential, genetic interactions and phenotypic effects, but the underlying determinants remain largely unresolved1,2,3,4,5. Here, to address these questions, we developed the Mouse Cancer Cell line Atlas, a broad-utility resource of 590 comprehensively characterized models across a wide range of entities (www.mcca.tum.de).
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Gordon Dougan

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By Gordon Dougan
| Gairdner Foundation
Opens in a new window Opens an external site Opens an external site in a new tab Professor, Department of Medicine, University of Cambridge, Cambridge, UK
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