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Articles by Libo Yang
Cold exposure aggravates vein occlusion through non-shivering thermogenesis-induced thrombocytopoiesis
Abstrats Vein occlusion (VO), including deep venous thrombosis (DVT) and retinal vein occlusion (RVO), is a common cause of multiple diseases that severely compromise the quality of life of affected individuals. Epidemiological evidence indicates that VO prevalence increases in cold seasons, yet the underlying mechanism remains unknown. Here, we show that cold exposure markedly elevates peripheral platelet counts, thereby aggravating VO in mouse models.
GLP-1 receptor agonists synergistic effects of metabolic reprogramming and cardioprotection
1 Introduction With the advancement of the social economy and alterations in lifestyle patterns, chronic metabolic disorders like obesity and diabetes have emerged as major public health issues (1, 2). The International Diabetes Federation (IDF) data shows that by 2021, approximately 537 million adults worldwide suffered from diabetes, accounting for nearly one-tenth of the global adult population (3).
A Two‐Tier Model‐Free Defense Approach Against False Data Injection Attacks in Two‐Area Load Frequency Control Systems
Conflicts of Interest The authors declare no conflicts of interest. References 1, , and , “Efficient Distributed MPC Using Kautz Functions for Load Frequency Control in Multi-Area Power Systems With Communication Delays,” IEEE Transactions on Sustainable Energy 1 (2025): 1–11, https://doi.org/10.1109/TSTE.2025.3552639. 2, , , , and , “Attack Detection in Automatic Generation Control Systems Using LSTM-Based Stacked Autoencoders,” IEEE Transactions on Industrial Informatics 19, no.
Clinical Outcome and Therapeutic Impact on Neuroendocrine Neoplasms of the Breast: A National Cancer Database Study
Purpose: Neuroendocrine neoplasms (NENs) of the breast are rare and not well-studied. NEN are subcategorized as well-differentiated neuroendocrine tumor (NET) and poorly differentiated neuroendocrine carcinoma (NEC). The objectives of the current study were to review the clinicopathologic features of NENs, therapeutic efficacy of current systemic therapy and clinical outcomes of NEN of the breast.
Sweetener aspartame aggravates atherosclerosis through insulin-triggered inflammation
Keywords atherosclerosis cardiovascular disease aspartame insulin chemokine artificial sweetener vascular inflammation insulin resistance macrophage stroke Introduction Artificial sweeteners (ASWs), also known as non-nutritive sweeteners (NNSs), as alternatives to caloric sugar are much appreciated by consumers.
Sweetener aspartame aggravates atherosclerosis through insulin-triggered inflammation
Keywords atherosclerosis cardiovascular disease aspartame insulin chemokine artificial sweetener vascular inflammation insulin resistance macrophage stroke Introduction Artificial sweeteners (ASWs), also known as non-nutritive sweeteners (NNSs), as alternatives to caloric sugar are much appreciated by consumers.
Data-Driven Analysis of Regional Ship Carbon Emission Reduction: The Bohai Bay Area Case Study
1. Introduction The issue of global climate change is becoming increasingly severe, and the pressure from the international community, especially from the Paris Agreement, has urged governments worldwide to take more proactive actions in emission reductions. With ships as the primary mode of maritime transport, their carbon emissions have gradually attracted the attention of the international community due to their growing share in global greenhouse gas emissions [].
Development and validation of a machine learning model for differentia
Dongmei Zhou,1,* Lingyu Shao,2,* Libo Yang,3,* Yongkang Chen,1,* Yue Zhang,4,* Feng Yue,3 Weipeng Gu,3 Shuyi Li,1 Shuyan Li,2 Jing Wei3 1Department of Rheumatology and Immunology, Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, People’s Republic of China; 2School of Medical Information and Engineering, Xuzhou Medical University, Xuzhou, Jiangsu, People’s Republic of China; 3Department of Endocrinology, The Affiliated Taian City Central Hospital of...
A Fractional Magnetic System with Critical Nonlinearities
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FA2H controls cool temperature sensing through modifying membrane sphingolipids in Drosophila
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Robust Feature Selection Method Based on Joint L2,1 Norm Minimization for Sparse Regression
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Dynamic Multi-Period Maritime Accident Susceptibility Assessment Based on AIS Data and Random Forest Model
This is an early access version, the complete PDF, HTML, and XML versions will be available soon.
Road Extraction from High-Resolution Remote Sensing Images via Local and Global Context Reasoning
2. Related Work 2.1. Traditional Road Extraction Methods Traditional road extraction methods primarily rely on manually designed features, such as spectrum, texture, and geometry, to distinguish roads from the background. We review existing research conducted at two different analytical scales: pixel-based methods and object-based methods []. These studies employ feature-based and classification-based approaches at varying analytical scales.
Butyrate suppresses atherosclerotic inflammation by regulating macrophages and polarization via GPR43/HDAC-miRNAs axis in ApoE−/− mice
PLOS ONE, Mar 2023 This is a preview of a remote PDF: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0282685&type=printable Huiyan Ma, Libo Yang, Yajuan Liu, Ru Yan, Rui Wang, Peng Zhang, Zhixia Bai, Yuanyuan Liu, Yi Ren, Yiwei Li, Xin Jiang, Ting Wang, Ping Ma, Qining Zhang, Aifei Li, Mixue Guo, Xiaoxia Zhang, Shaobin Jia, Hao Wang. , PLOS ONE, 2023, Volume 18, Issue 3, DOI: 10.1371/journal.pone.0282685
A Microwave Pressure Sensor Loaded with Complementary Split Ring Resonator for High-Temperature Applications
Open AccessArticle by Libo Yang 1,*, Hairong Kou 1,*, Xiaoli Wang 2, Xiaoyong Zhang 1, Zhenzhen Shang 1, Junbing Shi 1, Guanghua Zhang 1 and Zhiguo Gui 1,3 1 Shanxi Provincial Key Laboratory of Intelligent Sensing and Multi-Dimensional Information Processing, Taiyuan University, Taiyuan 030032, China 2 Jinxi Industries Group Co., Ltd, Taiyuan 030024, China 3 Shanxi Provincial Key Laboratory for Biomedical Imaging and Big Data, North University of China, Taiyuan 030051, China * Authors to whom...
Butyrate suppresses atherosclerotic inflammation by regulating macrophages and polarization via GPR43/HDAC-miRNAs axis in ApoE−/− mice
NaB consumption enriched intestinal butyrate-producing and anti-inflammatory bacteria Growing evidence has demonstrated that gut dysbiosis is closely associated with the development of AS [29, 34–37]. To further confirm the effects of NaB on gut microbiota in diverse groups, bacterial community were investigated by 16S rRNA sequencing and analysis.
Automated quantitative analysis of Ki-67 staining and HE images recognition and registration based on whole tissue sections in breast carcinoma
Min Feng1,2,3 na1, Yang Deng1 na1, Libo Yang1,3, Qiuyang Jing2, Zhang Zhang3, Lian Xu2,3, Xiaoxia Wei1,3,4, Yanyan Zhou1, Diwei Wu1, Fei Xiang5, Yizhe Wang5, Ji Bao1 & Hong Bu1,3 Diagnostic Pathology volume 15, Article number: 65 (2020) Cite this article Abstract Background The scoring of Ki-67 is highly relevant for the diagnosis, classification, prognosis, and treatment in breast invasive ductal carcinoma (IDC).
The differences of clinicopathologic characteristics among subgroups of reclassified HER2 fluorescence in situ hybridization (FISH) according to the ASCO/CAP 2018 breast cancer HER2 testing guidelines
The differences of clinicopathologic characteristics among subgroups of reclassified HER2 fluorescence in situ hybridization (FISH) according to the ASCO/CAP 2018 breast cancer HER2 testing guidelines Libo Yang1,2, Min Chen1, Tianjie Pu1,2, Shuang Wu1, Bing Wei1, Jieliang Yang1, Hong Bu1,2, Zhang Zhang1 1 Department of Pathology, West China Hospital of Sichuan University, Chengdu, Sichuan, China 2 Laboratory of Pathology, West China Hospital of Sichuan University, Chengdu, Sichuan, China...
The differences of clinicopathologic characteristics among subgroups of reclassified HER2 fluorescence in situ hybridization (FISH) according to the ASCO/CAP 2018 breast cancer HER2 testing guidelines
The differences of clinicopathologic characteristics among subgroups of reclassified HER2 fluorescence in situ hybridization (FISH) according to the ASCO/CAP 2018 breast cancer HER2 testing guidelines Libo Yang1,2, Min Chen1, Tianjie Pu1,2, Shuang Wu1, Bing Wei1, Jieliang Yang1, Hong Bu1,2, Zhang Zhang1 1Department of Pathology, West China Hospital of Sichuan University, Chengdu, Sichuan, China 2Laboratory of Pathology, West China Hospital of Sichuan University, Chengdu, Sichuan, China...
Machine learning approaches for predicting progression in hormone-sensitive prostate cancer patients
Introduction Prostate cancer ranks as the second most common malignancy in men worldwide, after lung cancer (1). Prognostic indicators such as Gleason score, prostate−specific antigen (PSA), and other serum markers have been shown to play important roles in assessing outcomes for prostate cancer patients (2). For instance, Ali Amin et al. (3) reported that a Gleason score of 4 + 3 = 7 is associated with an elevated risk of biochemical progression after radical prostatectomy.
Sphingosine 1-Phosphate, a Bioactive Sphingolipid Abundantly Stored in Platelets, Is a Normal Constituent of Human Plasma and Serum
Although sphingosine 1-phosphate (Sph-l-P) is reportedly involved in diverse cellular processes and the physiological roles of this bioactive sphingolipid have been strongly suggested, few studies have revealed the presence of Sph-l-P in human samples, including body fluids and cells, under physiological conditions. In this study, we identified Sph-l-P as a normal constituent of human plasma and serum.
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