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Articles by Ling Luo
Network analysis of symptom severity and symptom distress in hospitalized patients with decompensated cirrhosis
Abstract This study aimed to explore the network characteristics of symptom severity and symptom distress in hospitalized patients with decompensated cirrhosis, conduct an exploratory comparison of the two networks, and analyze factors associated with the occurrence of the symptom ranked highest in centrality within each network to inform clinical symptom management.
Early Changes in Peripancreatic Mesenteric Fat Beyond Weight Loss Predict Durability of Hepatic Improvements in MASLD
Conflicts of Interest The authors declare no conflicts of interest. Data Availability Statement The data analyzed in this study are available from the corresponding author upon reasonable request. The data are not publicly available because they contain information that could compromise participant privacy and are subject to ethical and institutional restrictions.
Tissue-Specific Insulin Resistance Pattern Underlies Heterogeneous Disease Severity and Complications in MASLD
Abstract Background Insulin resistance (IR) plays a pathophysiological role in the development of metabolic dysfunction-associated steatotic liver disease (MASLD). However, it remains unclear whether the specific distribution of IR across muscle, adipose tissue, hepatic tissue, and the whole body is associated with the heterogeneous disease severity and its complications.
Association between intrinsic capacity and trajectories of physical function among older adults: findings from a 10-year longitudinal cohort study
Abstract Objectives: To identify trajectories of basic activities of daily living (BADL) and instrumental activities of daily living (IADL) and determine whether the baseline intrinsic capacity (IC) deficit score predicts 10-year functional decline in older adults. Methods: Data were from the Chinese Longitudinal Healthy Longevity Survey (2008–2018, N = 2,045). A six-domain IC deficit score was constructed using the Integrated Care for Older People (ICOPE) framework.
Efficient White-Light-Excited Garnet NIR Phosphors With Robust Thermal Stability
1 Introduction NIR light plays a crucial role in various scientific and medical fields due to its unique properties and ability to penetrate materials [1]. With technological progress, NIR spectrum technology is increasingly being applied in biological detection methods, thereby enhancing the capabilities of imaging systems in various research and clinical settings [2-4].
Mycobacterium abscessus infection in a young man with cystic fibrosis: a case report and literature review
Abstract Background: Cystic fibrosis (CF) is a rare autosomal recessive disorder caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. Although relatively common in Caucasian populations, CF is rare in China, where it frequently presents with non-specific respiratory symptoms, leading to delayed diagnosis and frequent coinfections with multidrug-resistant pathogens.
Island ecosystems are pioneering the energy sector’s nature-positive transition Image: Unsplash/Steven Lynn SASAC Fellow and Director of Urban Energy Interconnection Research Center, State Grid Shanghai Electric Power Research Institute Vice Chair of ITU-T Study Group 5, International Telecommunication Union (ITU) China has been actively implementing the UN biodiversity framework through a series of national actions for conservation but economic sector players could undermine their roles in...
Collaborative dynamics in recreational vehicle campsite management: an evolutionary game and complex network analysis of stakeholders’ engagement
Abstract This study investigates stakeholder cooperation in the environmental governance of a public-good recreational vehicle campsite, combining evolutionary game theory with complex network simulations under two incentive scenarios. The results show that (1) the initial stakeholder network exhibits small-world characteristics, enabling efficient information exchange.
Havruta-structured dialogue as a social–emotional competence intervention: multi-stakeholder evidence on university students’ mental health
Abstract Introduction: This study evaluated the preliminary efficacy of a Havruta-structured dialogue program in enhancing university students’ social–emotional competence (SEC) and mental health. Methods: Ninety-five students were randomly assigned to either a Havruta intervention group (n = 47) or an active control group (n = 48). Assessments were conducted at baseline (T0), post-intervention (T1), and follow-up (T2).
XA-Novo: high-throughput mass spectrometry-based de novo sequencing technology for monoclonal antibodies and antibody mixtures
Abstract Elucidating antibody sequences by mass spectrometry-based de novo sequencing is essential but remains technically challenging. Here we present XA-Novo, an accurate and high-throughput de novo sequencing solution that integrates a single-pot multi-enzymatic gradient digestion method with a beam search-based assembler (Fusion) to reconstruct full-length antibody sequences directly from bottom-up mass spectrometry data.
Bias-targeted deep learning enhances short-range heavy rainfall forecasts - npj Climate and Atmospheric Science
Abstract Improving short-range forecasts of heavy rainfall remains a challenge. In recent years, deep-learning-based methods have been increasingly explored for post-processing precipitation forecasts from numerical weather prediction (NWP) models, but their performances are constrained by the non-negative and heavy-tailed nature of rainfall.
In Vitro Evaluation of Aerosol Delivery via a New High-Flow Nasal Cannula Device in Adult, Toddler, and Neonate Models
Abstract References Get access More Cite Share options Information, rights and permissions Metrics and citations Abstract Background: Nebulization through high-flow nasal cannula (HFNC) is increasingly used for aerosolized medication across various age groups. This study compared the aerosol delivery performance of a new HFNC device (O2FLO) with the Airvo 2 in simulated adult, toddler, and neonate models.
[2601.18588] Stability as a Liability:Systematic Breakdown of Linguistic Structure in LLMs
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Frontiers | Drivers of willingness to communicate with generative AI: the roles of self-efficacy, grit, speaking enjoyment, and anxiety from a self-determination theory perspective
1 Introduction The primary goal of English as a Foreign Language (EFL) education is to equip learners with the skills necessary for effective and confident communication in real-world contexts, encompassing listening, speaking, reading, and writing (Nation, 2008; Newton and Nation, 2020).
Overcoming Rigidity‐Flexibility Constraints in Garnet Phosphors for Broadband and Thermally Stable NIR Emission
Conflicts of Interest The authors declare no conflicts of interest. Data Availability Statement All data generated or analyzed during this study are included in this published article. Supporting Information Filename Description lpor70843-sup-0001-SuppMat.docx359.1 KB Supporting File: lpor70843-sup-0001-SuppMat.docx.
Overview of CHIP 2025 Shared Task 2: Discharge Medication Recommendation for Metabolic Diseases Based on Chinese Electronic Health Records
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CDrugRed: A Chinese Drug Recommendation Dataset for Discharge Medications in Metabolic Diseases
arXivLabs is a framework that allows collaborators to develop and share new arXiv features directly on our website. Both individuals and organizations that work with arXivLabs have embraced and accepted our values of openness, community, excellence, and user data privacy. arXiv is committed to these values and only works with partners that adhere to them. Have an idea for a project that will add value for arXiv's community? Learn more about arXivLabs.
[2510.08902] A Unified Biomedical Named Entity Recognition Framework with Large Language Models
arXivLabs is a framework that allows collaborators to develop and share new arXiv features directly on our website. Both individuals and organizations that work with arXivLabs have embraced and accepted our values of openness, community, excellence, and user data privacy. arXiv is committed to these values and only works with partners that adhere to them. Have an idea for a project that will add value for arXiv's community? Learn more about arXivLabs.
GSK461364 Inhibits NLRP3 Inflammasome by Targeting NEK7 Phosphorylation
1 Introduction The NLRP3 inflammasome, a multiprotein complex comprising NLRP3, ASC, and caspase-1, plays a pivotal role in host defense against pathogens and inflammatory responses.[1-3] Upon exposure to exogenous or endogenous stimuli, such as pathogen-derived proteins, lipids, nucleic acids, or crystalline materials, the complex assembles, leading to caspase-1 activation.
Effects of Obstructive Sleep Apnea on Cognition: An Analysis of Electroencephalography Microstates and Alpha Peak Frequency
1 Background Obstructive sleep apnea (OSA) is a sleep disorder that is characterized by recurrent episodes of upper airway obstruction, intermittent hypoxemia, and sleep fragmentation. The condition is prevalent in more than 55% of males and 30% of females over the age of 40 years [1]. Though a treatable disease, 80% of people with OSA remain undiagnosed and untreated [2].
Training Intensity Needed for Volume Linearity and Syringe DLCO Check Quality Control
Get full access to this article View all available purchase options and get full access to this article. References 1. Graham BL, Steenbruggen I, Miller MR, et al. Standardization of spirometry 2019 update. An official American Thoracic Society and European Respiratory Society Technical statement. Am J Respir Crit Care Med 2019;200(8):e70–e88; 2. Crapo RO, Jensen RL. Standards and interpretive issues in lung function testing. Respir Care 2003;48(8):764–772. 3. Clinical and Laboratory Standards Institute.
2024 Year in Review: Fugitive Aerosols—Keeping the Air Clear for Patients and Staff | Respiratory Care
Back to Top Get full access to this article View all available purchase options and get full access to this article. References 1. Sakai T, Morimoto Y. The history of infectious diseases and medicine. Pathogens 2022;11(10); 2. Jimenez JL, Marr LC, Randall K, et al. What were the historical reasons for the resistance to recognizing airborne transmission during the COVID-19 pandemic? Indoor Air 2022;32(8):e13070; 3. Teicher A. Super-spreaders: a historical review. Lancet Infect Dis 2023;23(10):e409–e417; 4.
The Impacts of Assimilating Radar Reflectivity for the Analysis and Forecast of “21.7” Henan Extreme Rainstorm Within the Gridpoint Statistical Interpolation–Ensemble Kalman Filter System: Issues with Updating Model State Variables
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Influence of Accelerated Carbonation on the Performance of Recycled Concrete Containing Fly Ash, Recycled Coarse Aggregate, and Fine Aggregate
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Study on the Chloride-Sulfate Resistance of a Metakaolin-Based Geopolymer Mortar
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Advances in osteoimmunomodulation of biomaterials after intrabone implantation: Focus on surface hydrophilicity
Advances in osteoimmunomodulation of biomaterials after intrabone implantation: Focus on surface hydrophilicity Biomaterials intended for intrabone implantation are extensively utilized in orthopedic and dental applications. Their surface properties, particularly hydrophilicity, significantly influence the biological interactions surrounding the implant, ultimately determining the implant's in-vivo fate.
EnzChemRED, a rich enzyme chemistry relation extraction dataset - Scientific Data
Abstract Expert curation is essential to capture knowledge of enzyme functions from the scientific literature in FAIR open knowledgebases but cannot keep pace with the rate of new discoveries and new publications. In this work we present EnzChemRED, for Enzyme Chemistry Relation Extraction Dataset, a new training and benchmarking dataset to support the development of Natural Language Processing (NLP) methods such as (large) language models that can assist enzyme curation.
Obesity aggravates the role of C‐reactive protein on knee pain: A cross‐sectional analysis with NHANES data
1 INTRODUCTION Chronic pain is an unpleasant sensory and emotional experience associated with, or potential tissue damage, or described in terms of such damage, containing joint pain, with the knee being a frequently affected site.1, 2 Knee pain is one of the most common clinical complaints in adults, with about half of middle-aged and elderly people over 50 years old experiencing it.3 It is a serious public health problem that needs to be solved urgently, as one in six individuals with knee...
Optimal Resilience and Risk-Driven Strategies for Pre-Disaster Protection of Electric Power Systems against Uncertain Disaster Scenarios
1. Introduction Electric power systems are vital lifeline infrastructures essential for the sustainable growth of contemporary society, supporting economic, commercial, and social endeavors. Despite the necessity for the continuous and secure operation of power systems, they are inevitably susceptible to various natural disasters. Between 2000 and 2022, there were 8749 recorded natural disaster events worldwide, including floods, extreme weather conditions, hurricanes, and earthquakes.
Local Contrast Learning for One-Shot Learning
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Effect of Recycled Fine Aggregates on the Mechanical and Drying Shrinkage Properties of Alkali-Activated Recycled Concrete
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Optimized strategy among diet, exercise, and pharmacological interventions for nonalcoholic fatty liver disease: A network meta‐analysis of randomized controlled trials
ACC acetyl-CoA carboxylase AEx aerobic exercise ALT alanine aminotransferase BBR berberine BMI body mass index CAP controlled attenuation parameter DPP4 dipeptidyl peptidase-4 FXR farnesoid X receptor GGT γ-glutamyltranspeptidase GLP-1 glucagon-like peptide-1 IR insulin resistance LDL-C low density lipoprotein cholesterol LSM liver stiffness measurement MRE magnetic resonance elastography.
Lactate Conversion by Lactate Dehydrogenase B Is Involved in Beige Adipocyte Differentiation and Thermogenesis in Mice
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Ba3(BS3)(PS4): The First Alkaline-Earth Metal Thioborate-Thiophosphate with Strong Optical Anisotropy Originated from Planar [BS3] Units
Ba3(BS3)(PS4): The First Alkaline-Earth Metal Thioborate-Thiophosphate with Strong Optical Anisotropy Originated from Planar [BS3] Units The first alkaline-earth metal thioborate-thiophosphate Ba3(BS3)(PS4) was designed from Ba3(BO3)(PO4) by the S-O substitution and fabricated in experiment. The formed [BS3] pseudo-layers in the structure contribute to strong optical anisotropy and a large birefringence of ~0.11@1064 nm. The results enrich the structural and chemical diversity of chalcogenides.
Alterations in Circulating Bile Acids in Metabolic Dysfunction-Associated Steatotic Liver Disease: A Systematic Review and Meta-Analysis
1. Introduction Metabolic dysfunction-associated steatotic liver disease (MASLD), previously known as nonalcoholic fatty liver disease (NAFLD), affects approximately 32.4% of the adult population worldwide and places a large health and economic burden on global society [1].
MB3P2S10 (M = Rb, Cs): Two New Alkali Metal Thioboratephosphates with [B6P4S20] T3-Supertetrahedra
MB3P2S10 (M = Rb, Cs): Two New Alkali Metal Thioboratephosphates with [B6P4S20] T3-Supertetrahedra Jiazheng Zhou, Xin Su, Ling Luo, Junjie Li and Feng Yu Abstract Two new alkaline metal thioboratephosphates, RbB3P2S10 and CsB3P2S10, have been designed and fabricated by the flux method. The two compounds are composed of alkali metal polyhedral and [B6P4S20] T3-supertetrahedral units, and crystallize in I41/a and R-3c space groups, respectively.
Buckling Enhancement Analysis of Auxetic Laminated Rectangular Plate under Uniaxial Compression
This is an early access version, the complete PDF, HTML, and XML versions will be available soon. Open AccessArticle by Kai Wang 1, Feng Wan 1, Ling Luo 1,*, Pengyu Cao 1, Lei Han 1 and Peng Jin 2 1 Aerospace Institute of Advanced Materials and Processing Technology, Beijing 100074, China 2 School of Aerospace Engineering, Huazhong University of Science & Technology, Wuhan 430074, China * Author to whom correspondence should be addressed. Appl. Sci.
Oral health literacy and its associated factors among nurses: A cross‐sectional study
Abstract Aims and Objectives To investigate the oral health literacy (OHL) of nurses and explore the factors affecting their OHL. Background OHL is important for improving the oral health outcomes. Nurses' OHL may affect the oral health of themselves, families, and patients. Few studies have examined the OHL and its related factors among nurses. Design A cross-sectional design following the STROBE guideline.
Applying the DEMATEL−ANP Fuzzy Comprehensive Model to Evaluate Public Opinion Events
Abstract : Network public opinion is a mirror reflecting people’s will, and evaluating its urgency can help to find hidden social crises. Research on public opinion in the field of machine learning usually focuses on micro-sentiment judgment, which is unable to offer support for the evaluation of public opinion events without additional data, and research from the perspective of artificial weighting has the disadvantage of the confusion of explanation.
Do Urban Innovation Policies Reduce Carbon Emission? Empirical Evidence from Chinese Cities with DID
This is an early access version, the complete PDF, HTML, and XML versions will be available soon. Open AccessArticle by 1, 1,* and 2 1 Department of Public Management, School of Government, Shenzhen University, Shenzhen 518060, China 2 Department of Human Resource Management, College of Management, Shenzhen University, Shenzhen 518060, China * Author to whom correspondence should be addressed.
Discovery of 1,2,4-Oxadiazole Derivatives Containing Haloalkyl as Potential Acetylcholine Receptor Nematicides
3. Materials and Methods 3.1. Instruments and Chemicals The reaction process was monitored by thin-layer chromatography (TLC) with a 254 nm UV detector. Column chromatography was performed on 200–300 mesh silica gel. The melting points were recorded using an uncorrected X-4B microscope melting point apparatus (Shanghai Electrophysical Optical Instrument Co., Ltd., Shanghai, China).
Machine Learning Approach to Facilitate Knowledge Synthesis at the Intersection of Liver Cancer, Epidemiology, and Health Disparities Research
Article Tools ORIGINAL REPORTS Cancer Prevention and Epidemiology Abstract Full Text PDF Figures and Tables Supplements Abstract Liver cancer is a global challenge, and disparities exist across multiple domains and throughout the disease continuum.
Machine Learning Approach to Facilitate Knowledge Synthesis at the Intersection of Liver Cancer, Epidemiology, and Health Disparities Research
Abstract Liver cancer is a global challenge, and disparities exist across multiple domains and throughout the disease continuum. However, liver cancer's global epidemiology and etiology are shifting, and the literature is rapidly evolving, presenting a challenge to the synthesis of knowledge needed to identify areas of research needs and to develop research agendas focusing on disparities.
A Sequence Labeling Framework for Extracting Drug-Protein Relations from Biomedical Literature
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A Novel Sequence Labeling Framework for Extracting Drug-Protein Relations from Biomedical Literature
Abstract Automatic extracting interactions between chemical compound/drug and gene/protein is significantly beneficial to drug discovery, drug repurposing, drug design, and biomedical knowledge graph construction. To promote the development and evaluation of systems that are able to automatically detect in relations between drug and protein, the DrugProt track was organized during the BioCreative VII challenge. This paper describes our approach to this challenging task.
Na4Ga8S14: A Ga-riched wide band gap ternary alkali-metal sulfide with unique [Ga12S42] 12-menbered rings
Na4Ga8S14: A Ga-riched wide band gap ternary alkali-metal sulfide with unique [Ga12S42] 12-menbered rings A Ga-riched ternary alkali-metal sulfide Na4Ga8S14 has been synthesized by high temperature solid-state reaction. It crystallizes in the centrosymmetric Pbca (no.
Artificial Intelligence in Action: Addressing the COVID-19 Pandemic with Natural Language Processing
Annual Review of Biomedical Data Science Vol.
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