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Articles by Lingling Chen
Association Between Cerebrospinal Fluid Ghrelin Levels and Depressive Symptoms is Moderated by Smoking: A Case-Control Study
1 Introduction Depression is a pervasive and debilitating mental disorder that has become a significant global social and public health issue. Currently, more than 264 million people worldwide suffer from depression across all age groups (Liu et al. 2020). Depression ranks as the leading mental disorder in terms of disease burden globally (Kong et al.
Lattice Model and Differential Equation Model of Territorial Competition in Cyclic Vegetation Communities
You are already at the latest version Spatial self-organized patterns are ubiquitous features of vegetation ecosystems, and cyclic nontransitive competition serves as a crucial intrinsic mechanism for sustaining biodiversity. However, existing studies lack cross-scale comparative analyses of vegetation territorial competition based on multiple models.
Precursor transformation and microbial responses during compost humification regulated by wood vinegar produced at different pyrolysis temperatures
Abstract The humification stage is a critical that determines compost quality, and the addition of functional exogenous materials is an important measure to promote this stage. Cotton-stalk-derived wood vinegar, a bioactive liquid by-product of cotton stalk pyrolysis, may regulate compost humification by modulating organic matter transformation and microbial metabolism. However, the yield of these components is significantly influenced by the pyrolysis temperature.
Causality-Based Multimodal Identity Recognition Method
L.Chen, Y.Zheng, C.Ma, J.Zhu, X.Guo, and S.Guo, “Causality-Based Multimodal Identity Recognition Method,” Concurrency and Computation: Practice and Experience38, no. 10 (2026): e70751, https://doi.org/10.1002/cpe.70751. Conflicts of Interest The authors declare no conflicts of interest. Data Availability Statement The data that support the findings of this study are available from the corresponding author upon reasonable request.
Phase 1 pilot study for hemophilia-A: AAV8 vector with prophylactic tacrolimus-glucocorticoid achieves therapeutic FVIII activity
Abstract This prospective phase 1 pilot study evaluated the safety and efficacy of GS001, an adeno-associated virus serotype 8 (AAV8)-based vector encoding B-domain–deleted factor VIII with exploratory assessment of prophylactic immunosuppression. Twelve adult severe hemophilia A participants were enrolled.
Designing a broad-spectrum multi-epitope vaccine against influenza A and Mycoplasma pneumoniae: an immunoinformatics approach
ORIGINAL RESEARCH article Volume 14 - 2026 | https://doi.org/10.3389/fpubh.2026.1671035 1 Introduction The influenza A virus and M. pneumoniae are formidable adversaries in respiratory disease. Influenza A virus belongs to the most studied virus and its mutant initiates epidemic and pandemics outbreaks. The high transmissibility and antigenic variability of influenza A virus drive the annual epidemic, with H1N1, H3N2, and avian H5N1 strains alone causing 290,000–650,000 global deaths annually (1).
De Novo High-Titer Biosynthesis of (−)-α-Bisabolol in Engineered Candida tropicalis via Green Metabolic Engineered Strategies
Abstract Click to copy section linkSection link copied! (−)-α-bisabolol, a valuable sesquiterpene with anti-inflammatory and antibacterial properties, was sustainably produced via de novo high-titer biosynthesis in Candida tropicalis using engineered cell factories.
A systematic review of factors influencing spatial characteristics of rural settlements
ABSTRACT Rural settlements are experiencing significant transformations. Understanding the factors and mechanisms influencing their spatial evolution is important for effective planning and long-term development. This study analyzes scholarly articles on the spatial characteristics and evolution of rural settlements, published in the Web of Science and Scopus since 2019.
A Comprehensive IndetermHyperSoft Set Model for Evaluating University Literature Education Effectiveness: Integrating Cultural Context, Argumentation Skills, and Dynamic Progress
Recommended Citation Chen, Lingling. "A Comprehensive IndetermHyperSoft Set Model for Evaluating University Literature Education Effectiveness: Integrating Cultural Context, Argumentation Skills, and Dynamic Progress." Neutrosophic Sets and Systems 87, 1 (2025). https://digitalrepository.unm.edu/nss_journal/vol87/iss1/21
MCT1‐mediated Lactate Shuttle to Mitochondria Governs Macrophage Polarization and Modulates Glucose Homeostasis by Affecting β Cells
1 Introduction Macrophages can be polarized into a classically activated state, termed “M1-like,” by lipopolysaccharide (LPS) or interferon-γ (IFN-γ), or into an alternative anti-inflammatory state, called “M2-like,” by interleukin-4 (IL-4).
Measuring Teaching Success in College Foreign Literature Programs: An Evaluation Perspective using Double Framed SuperHyperSoft Set
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Broad-Spectrum Multi-Epitope Vaccine Against Mycoplasma pneumoniae Based on Reverse Vaccinology
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Nationwide Study on Factor V Deficiency in China: Clinical Characteristics, Genotype, and Treatment Approaches
Conflicts of Interest The authors declared no conflicts of interest. Supporting Information Filename Description hae70066-sup-0001-SuppMat.docx18 KB Supporting File 1: hae70066-sup-0001-SuppMat.docx References 1, , and , “Inherited Defects of Coagulation Factor V: The Hemorrhagic Side,” Journal of Thrombosis and Haemostasis 4, no. 1 (2006): 26–34. 2 and , “Factor V: A Combination of Dr Jekyll and Mr Hyde,” Blood 101, no. 1 (2003): 20–30.
Knowledge, Attitudes, and Practices of Chinese Breast Cancer Patients Towards Comprehensive Postoperative Self-Management: a Cross-Sectional Study
Abstract Purpose To comprehensively assess the knowledge, attitudes, and practices (KAP) of Chinese breast cancer (BC) patients regarding postoperative self-management (POSM) and identify factors influencing self-management behaviors. Methods Questionnaire surveys were administered to BC patients who underwent surgery. A total of 566 participants (98.94% female), mainly from rural areas (65.55%) and married (97.53%), were included.
Health Justice Partnership: An Opportunity to Respond to Childhood Adversity
Introduction Childhood adversity encompasses a range of traumatic or stressful events that occur in childhood such as child abuse and neglect, parental mental health disorders, family violence, parental drug abuse, and community violence and has been recognised as a significant contributor to poor mental and physical health in later life [1]. Adversities tend to cluster in families with higher number of adversities associated with poorer outcomes [2].
Microbial‐type terpene synthases significantly contribute to the terpene profile of glandular trichomes of the fern Dryopteris fragrans (L.)
CONFLICT OF INTEREST The authors declare no conflict of interest. Supporting Information Filename Description tpj70079-sup-0001-supinfo.pdfPDF document, 1.8 MB Table S1. Concentrations of metabolites identified from intact and abraded leaves. Table S2. Expression of DfMTPSL genes based on transcriptome analysis. Table S3. NMR data of (−)-9-epi-presilphiperfolan-1-ol in C6D6 recorded at 298 K. Table S4. Primers for cloning of MTPSL genes in Dryopteris fragrans. Table S5.
Acceptability, Feasibility, and Preliminary Effectiveness of a Wellbeing Coordination Program in an Integrated Health and Social Care Hub: A Mixed Methods Study | International Journal of Integrated Care
Introduction Families with children experiencing adverse childhood adversities (ACEs), including maltreatment, household dysfunction, community dysfunction, and peer dysfunction [1], often have complex needs requiring support and care from multiple services [2].
Mediation Effect of CSF Substance P on the Association Between Smoking and Sleep
1 Introduction Cigarette smoking poses a significant global health threat, causing harm to nearly every organ in the body. It stands as the primary culprit behind over 30% of all cancer-related deaths, 80% of chronic obstructive pulmonary disease fatalities, and a substantial portion of premature cardiovascular mortality (G. B. D. T. Collaborators 2017).
A co-designed health education model to improve outcomes for children with emotional and behavioural difficulties: a study of acceptability, feasibility and impacts
Abstract Objective To assess the acceptability and impacts of a co-designed health education model aiming to improve outcomes for children with emotional and behavioural difficulties. Design Qualitative focus group study. Setting Six primary schools from metropolitan and rural settings in the state of Victoria, Australia. Participants 36 educators who engaged with the intervention between July and December 2021.
Comprehensive Health Assessment of School‐Age Children Conceived by Assisted Reproductive Technology: A Prospective Cohort Follow‐Up Study
Data Availability Statement Clinical data are not available to the public due to protection of patient privacy. Deidentified participant data will be provided by the corresponding author for research purposes. Written protocols are required for analysis, including an analysis plan and signed data sharing/access agreement. Data sharing requests will be processed in accordance with the data access and sharing regulations of Human Genetic Resource Administration of China.
LncRNA 93358 Aggravates the Apoptosis of Myocardial Cells After Ischemia‐Reperfusion by Mediating the PI3K/AKT/mTOR Pathway
1 Introduction In recent years, the morbidity of acute myocardial infarction (AMI) in China has been increasing annually, which triggers the attention from experts and scholars widely [1]. Strategies for the treatment of AMI in clinic mainly include surgery, thrombolytic therapy, interventional therapy, and so forth, which show a certain therapeutic effect.
Knowledge, Attitudes, and Practices of Breast Cancer Patients towards | JMDH
Introduction Breast cancer (BC), characterized by the uncontrolled proliferation of abnormal cells in breast tissue, presents a significant global health challenge, with 2.3 million cases diagnosed and 670,000 deaths recorded in 2022 alone.1 In China specifically, breast cancer has become the most commonly diagnosed cancer among women, with approximately 416,371 new cases and 117,174 deaths reported in 2020.2 The age-standardized incidence rate has increased from 21.6 per 100,000 women in...
Resuscitation-promoting factor (Rpf) terminates dormancy among diverse soil bacteria
Abstract Microorganisms often inhabit environments that are suboptimal for growth and reproduction. To survive when challenged by such conditions, individuals may engage in dormancy where they enter a metabolically inactive state. For this persistence strategy to confer an evolutionary advantage, microorganisms must be able to resuscitate and reproduce when conditions improve.
Intestinal Inflammation and Permeability Biomarkers Associated with Gl
Back to Journals » Journal of Inflammation Research » Volume 17 Authors Wang Z, Guo S, He C, Chen L, Wang J, Xiu W, Zhang G, Chen Y, Li A, Zhu X, Xiao X, Yu L , Lu F Received 1 August 2024 Accepted for publication 24 September 2024 Published 30 September 2024 Volume 2024:17 Pages 6895—6904 DOI https://doi.org/10.2147/JIR.S480809 Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 3 Editor who approved publication: Professor Ning Quan Zuo Wang,1,2,*...
Synergy of Oxygen Vacancy and Surface Modulation Endows Hollow Hydrangea-Like MnCo2O4.5 with Enhanced Capacitive Performance
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GhTKPR1_8 functions to inhibit anther dehiscence and reduce pollen viability in cotton
Supporting Information Filename Description ppl14331-sup-0001-Figures.pdfPDF document, 1.1 MB Fig. S1. Phylogenetic tree of the TETRAKETIDE a-PYRONE REDUCTASE1 (TKPR1) gene family. Groups α, β, and γ are the phylogenetic clusters of the genes. Different groups are represented with varying background colors. The scale bar indicates the rates of substitutions per site. Figure S2. Comprehensive characteristic analysis of the TKPR1 gene family in upland cotton. Figure S3.
Coupling and Coordination between Tourism, the Environment and Carbon Emissions in the Tibetan Plateau
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Treatment of vitiligo and alopecia areata in a child
Back to Journals » Clinical, Cosmetic and Investigational Dermatology » Volume 17 Authors Mu Y, Pan T, Chen L Received 22 April 2024 Accepted for publication 29 July 2024 Published 6 August 2024 Volume 2024:17 Pages 1789—1792 DOI https://doi.org/10.2147/CCID.S467026 Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 4 Editor who approved publication: Dr Monica K.
DayCost - Personal Finance, Money Manager, Income, Expense & Budget
What's New Bug fix... Category: Finance OS: iOS Compatible: iPhone iPad Requirements: Requires iOS 7.0 or la money budget expense income daycost income expense income expense budget Description - DayCost - Personal Finance, Money Manager, Income, Expense & Budget . url schemes hcbilltrackerwidget. found in 1 reviews in addition we also give several redemption code as a gift. found in 1 reviews try our daycost it she will be your best assistant.
IoT-based RMT for COPD
Back to Journals » International Journal of Chronic Obstructive Pulmonary Disease » Volume 19 Authors Chen Q, Wu X, Huang Y, Chen L Received 14 December 2023 Accepted for publication 14 May 2024 Published 22 May 2024 Volume 2024:19 Pages 1093—1103 DOI https://doi.org/10.2147/COPD.S454804 Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 3 Editor who approved publication: Dr Richard Russell Qiong Chen,1,* Xuejuan Wu,1,* Yanjin Huang,2 Lingling...
Effects of Restoration Strategies on the Ion Distribution and Transport Characteristics of Medicago sativa in Saline-Alkali Soil
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Molecules | Free Full-Text | NiMoO4 Nanosheets Embedded in Microflake-Assembled CuCo2O4 Island-like Structure on Ni Foam for High-Performance Asymmetrical Solid-State Supercapacitors
3. Experimental All of the reagents used in the experiments were of analytical grade and were used without further purification. Prior to the synthesis, the Ni foam was cleaned by acetone, ethanol and deionized water for 20 min in sequence with sonication. CuCo2O4, NiMoO4 and CuCo2O4/NiMoO4 were prepared by the hydrothermal method. In this work, activated carbon (YP50) was purchased from Kuraray Co., Ltd. (Tokyo, Japan). The other reagents were purchased from Sinopharm Chemical Reagents Co., Ltd.
GhSTP18, a member of sugar transport proteins family, negatively regulates salt stress in cotton
Corresponding Author Shuli Fan National Key Laboratory of Cotton Bio-breeding and Integrated Utilization, Institute of Cotton Research, Chinese Academy of Agricultural Sciences, Anyang, Henan, China National Nanfan Research Institute (Sanya), Chinese Academy of Agricultural Sciences, Sanya, China Zhengzhou Research Base, National Key Laboratory of Cotton Bio-breeding and Integrated Utilization, School of Agricultural Sciences, Zhengzhou University, Zhengzhou, Henan, China Hainan Yazhou Bay...
Fast and Secure Image Encryption Algorithm with Simultaneous Shuffling and Diffusion Based on a Time-Delayed Combinatorial Hyperchaos Map
4.2. Key-Space and Key-Sensitivity Analyses A secure and effective encryption algorithm requires the support of a sufficiently large key space. The key of this algorithm consists of 256 binary digits, so its key space is 2 256 . Due to current computer hardware conditions, this key has enough space to resist brute-force cracking.
Metals | Free Full-Text | The Parameter Identification of Physical-Based Constitutive Model by Inverse Analysis Method for Application in Near-Net Shape Forging of Aluminum Wheels
Abstract : A reliable constitutive model is a prerequisite to simulate a new complex forming technique, which is represented by the near-net shape forging process of aluminum wheels in this study.
Preparation and Investigation of Ni–Co–P Alloy Coatings Using Jet Electrodeposition with Varying Pulse Parameters
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Ultrahigh energy density with excellent thermal stability in lead-free multilayer ceramic capacitors via composite strategy design
Ultrahigh energy density with excellent thermal stability in lead-free multilayer ceramic capacitors via composite strategy design Peiyao Zhao, Lingling Chen, Longtu Li and Xiaohui Wang Abstract Dielectric capacitor has received growing interest for advanced electrical and electronic systems. However, the low energy density and poor thermal stability at high temperature severely hinder its practical applications.
Photocatalyst and additive-free visible light induced trifluoromethylation-arylation of N-arylacrylamides with Umemoto′s reagent
Photocatalyst and additive-free visible light induced trifluoromethylation-arylation of N-arylacrylamides with Umemoto′s reagent You have access to this article Please wait while we load your content... Something went wrong. Try again?
Ultra-high energy storage performance in lead-free multilayer ceramic capacitors via a multiscale optimization strategy
Ultra-high energy storage performance in lead-free multilayer ceramic capacitors via a multiscale optimization strategy† Peiyao Zhao,‡a Ziming Cai, ‡ab Lingling Chen,a Longwen Wu,c Yu Huan,d Limin Guo, e Longtu Li,a Hong Wang *f and Xiaohui Wang*a Author affiliations * Corresponding authors a State Key Laboratory of New Ceramics and Fine Processing, School of Materials Science and Engineering, Tsinghua University, Beijing 100084, China E-mail: wxh@mail.tsinghua.edu.cn b School of Material...
Influence of exogenous ascorbic acid and glutathione priming on mitochondrial structural and functional systems to alleviate aging damage in oat seeds
Abstract Background Loss of vigor caused by seed aging adversely affects agricultural production under natural conditions. However, priming is an economical and effective method for improving the vigor of aged seeds. The objective of this study was to test the effectiveness of exogenous ascorbic acid (ASC) and glutathione (GSH) priming in the repairing of aged oat (Avena sativa) seeds, and to test the hypothesis that structural and functional systems in mitochondria were involved in this process.
Correction for Degtyareva et al., “Chronic Oxidative DNA Damage Due to DNA Repair Defects Causes Chromosomal Instability in Saccharomyces cerevisiae”
Correction for Degtyareva et al., “Chronic Oxidative DNA Damage Due to DNA Repair Defects Causes Chromosomal Instability in Saccharomyces cerevisiae” Natalya P. Degtyareva, Lingling Chen, Piotr Mieczkowski, Thomas D. Petes, Paul W. Doetsch Molecular and Cellular Biology Oct 2019, 39 (21) e00407-19; DOI: 10.1128/MCB.00407-19
Author Correction: Pollinator-mediated selection on flowering phenology and floral display in a distylous herb Primula alpicola
Correction to: Scientific Reports https://doi.org/10.1038/s41598-017-13340-0, published online 13 October 2017 This Article contains errors. In Figure 1 the two fitted curves should be shown as dashed lines. The correct Figure 1 appears below. Figure 1 Number of flowering individuals, fruit set (proportion of flowers forming a fruit), and pre-dispersal seed herbivory (proportion of damaged flowers and fruits) with date in one P. alpicola population at Lulang, China in 2016.
Grain configuration effect on the phase transition, piezoelectric strain and temperature stability of KNN-based ceramics
Grain configuration effect on the phase transition, piezoelectric strain and temperature stability of KNN-based ceramics Zhenyong Cen,a Yan Yu,a Peiyao Zhao,a Lingling Chen,a Chaoqiong Zhu,a Longtu Lia and Xiaohui Wang*a Author affiliations * Corresponding authors a State Key Laboratory of New Ceramics and Fine Processing, School of Materials Science and Engineering, Tsinghua University, Beijing 100084, China E-mail: wxh@tsinghua.edu.cn Abstract Lead-free 0.985(0.96KNNT–0.04BNKZ)–0.015CZ...
Grain configuration effect on phase transition, piezoelectric strain and temperature stability of KNN-based ceramics
Grain configuration effect on phase transition, piezoelectric strain and temperature stability of KNN-based ceramics Zhenyong Cen, Yan Yu, Peiyao Zhao, Lingling Chen, Chaoqiong Zhu, Longtu Li and Xiao-Hui Wang Abstract Lead-free 0.985(0.96KNNT-0.04BNZ)-0.015CZ ceramics have been sintered in 1150-1190 oC. The average grain size increases from ~0.54 µm to ~1.26 µm with increasing sintering temperature (TSinter) from 1150 oC to 1190 oC.
Kinematic features in patients with lateral discoid meniscus injury during walking
This study explores the kinematic characteristics of knees with lateral meniscus injury and lateral discoid meniscus injury, as well as those of healthy knees, using a portable optical tracking system. The results indicate that the two groups of patients with meniscus injury exhibited smaller ROMs than those with healthy knee joints. A few studies show that the symptoms of discoid meniscus injury are similar to those of normal meniscus injuries, such as pain, popping, and snapping.
Rice Functional Genomics Research: Past Decade and Future
Table 2Representative Genes Related to Agronomically Important Traits in Rice.GeneAccession numberFunctional annotationControlling traitReferencesAn-1LOC_Os04g28280Basic HLH proteinYieldLuo et al., 2013bxAn-1 encodes a basic helix-loop-helix protein that regulates awn development, grain size, and grain number in rice. Luo, J., Liu, H., Zhou, T., Gu, B., Huang, X., Shangguan, Y., Zhu, J., Li, Y., Zhao, Y., Wang, Y. et al. Plant Cell.
The osteoimmunomodulatory property of a barrier collagen membrane and its manipulation via coating nanometer-sized bioactive glass to improve guided bone regeneration
A barrier membrane is a major component of guided bone regeneration (GBR), which is traditionally viewed as a physical barrier. Due to its “foreign body” nature, the implantation of a barrier membrane would inevitably modulate immune response and subsequently affect bone dynamics, which has long been neglected. To bridge this knowledge gap, we investigated the osteoimmunomodulatory effects of barrier collagen membranes.
Considering the Characteristics of Traffic Risk Factors and the Method of Establishing a Flexible Traffic System
Journal of Advanced Transportation PDF For authorsFor reviewersFor editorsTable of Contents Submit Journal of Advanced Transportation / 2022 / Article Research Article | Open Access Lingling Chen, Yuanyuan Zhang, "Considering the Characteristics of Traffic Risk Factors and the Method of Establishing a Flexible Traffic System", Journal of Advanced Transportation, vol. 2022, Article ID 6597685, 13 pages, 2022.
Tanshinone IIA ameliorated endothelial dysfunction in rats with chronic intermittent hypoxia
Publication HistoryPublished online: June 30, 2017Accepted: June 26, 2017; Received in revised form: June 7, 2017; Received: December 14, 2016;
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