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Marius Wernig

As seen in: Nature, The Conversation, Science Magazine, Medical Xpress, Cell Press, Cell Stem Cell, Stem Cell Reports, Singularity Hub, JNeurosci, Missoulian and
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Articles

Tethered agonist– and GAIN domain–independent signaling of an adhesion GPCR

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By Yu Sun, Jie Wang, Haoyu Hu, Yi Miao, Jinzhao Wang, Yu ZHANG, Ahmed Yousif, Marius Wernig, Thomas C. Südhof, Shaoyuan Zhu, Tsz Lok Wong
| Science Magazine Verified
Abstract INTRODUCTION RESULTS DISCUSSION MATERIALS AND METHODS Acknowledgments Supplementary Materials REFERENCES Information & Authors Metrics & Citations View Options References Figures Tables Media Share Abstract In transfected cells, adhesion G protein–coupled receptors (GPCRs) are activated by tethered agonists that are embedded in their canonical autoproteolytic GAIN domain.
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Prevention of transgene silencing during human pluripotent stem cell differentiation

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By Takeshi Uenaka, Alan Napole, Aninda Dibya Saha, Duo Sun, Jiahui Chen, Lena Erlebach, Amanda McQuade, Daniel Ramos, Alessandra Rigamonti, Lisa Salazar, Avi J. Samelson, Natalie Welsh, Qianxin Wu, Ernest Arenas, Andrew Bassett, Martin Kampmann, Deborah Kronenberg-Versteeg, Florian T. Merkle, Leslie Thompson Verified, William C Skarnes, Michael Ward, Marius Wernig, Angelina Singavarapu, Elizabeth Calzada, Kamilla Sedov, Katleen Wild, Birgitt Schüle
| Cell Stem Cell Verified
TechnologyVolume 33, Issue 3p517-530.e8Open access Affiliations & Notes 1Institute for Stem Cell Biology & Regenerative Medicine, Stanford University School of Medicine, Stanford, CA, 94305, United States of America 2Department of Pathology, Stanford University School of Medicine, Stanford, CA, 94305, United States of America 3The Phil & Penny Knight Initiative for Brain Resilience at the Wu Tsai Neurosciences Institute, Stanford University, Stanford, CA, 94305, United States of America...
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Cell-type resolved protein atlas of brain lysosomes identifies SLC45A1-associated disease as a lysosomal disorder

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By Ali Ghoochani, Julia C. Heiby, Eshaan S. Rawat, Uche Medoh, Domenico Di Fraia, Wentao Dong, Mohit Rastogi, Vincent Hernandez, Kwamina Nyame, Nouf N. Laqtom, William DUrso, Christina Valkova, Alina Isakova, Christoph Kaether, Marius Wernig, Natalia Gomez-Ospina, Christian Franke Verified, Alessandro Ori, Monther Abu-Remaileh, Marc Gastou, Vincent Hernandez, Marc Gastou
| Cell Press Verified
Plasmid construction Gene fragments for lysosomal localization validation were ordered from TWIST Bioscience (Gene fragments without Adapters, codon optimized; encoding proteins: EDIL3, ENPP5, PLEKHB1), and IDT (gblocks; encoding proteins: TMEM88B, TMEM256, CBLN3).
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