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Articles by Mingwei Wang
DGKE acts as a negative regulator of podocyte migration and injury in glomerular diseases
Abstract Podocyte injury is a major determinant of glomerular diseases. Although considerable advances have been made in the understanding of the mechanisms that trigger podocyte injury, effective cell-specific therapies remain clinically unavailable. In particular, recent studies have revealed that podocyte adhesion dysfunction and aberrant migration are pivotal events in the pathogenesis of podocyte loss and injury.
Causal landscape of the circulating proteome in systemic iron overload revealed by Mendelian randomization and experimental validation
Abstract Systemic iron overload precipitates progressive and often irreversible organ dysfunction, yet the clinical toolkit for non-invasive, organ-specific monitoring of iron accumulation remains inadequate. This study leverages a proteome-wide causal inference framework to identify circulating biomarkers that drive or reflect iron deposition in the liver, spleen, and pancreas.
p300-Mediated H3K18 Lactylation Drives Radiation-Induced Pulmonary Fibrosis via VIRMA-Dependent m6A Modification of GATA3
1 Introduction Radiation-induced pulmonary fibrosis (RIPF) is a devastating, permanent consequence of thoracic radiation [1, 2], characterized by progressive alveolar destruction and massive extracellular matrix (ECM) deposition [3, 4]. As the principal progenitors maintaining pulmonary homeostasis, type II alveolar epithelial cells (AECIIs) paradoxically exacerbate RIPF by undergoing epithelial-mesenchymal transition (EMT) [5], acting as a major source of lesional fibroblasts.
Risk factors and a predictive model for delayed extubation in children undergoing primary repair of tetralogy of Fallot: a retrospective cohort study with rigorous methodological validation
Abstract Objective: To identify independent risk factors for delayed extubation (mechanical ventilation 48 h) following primary Tetralogy of Fallot (TOF) repair and to develop a rigorously validated predictive model for clinical use. Methods: A retrospective cohort study was conducted involving 189 children treated at Henan Chest Hospital between 2019 and 2023. Patients were stratified into delayed (n = 101) and non-delayed (n = 88) extubation groups.
Origin of crack propagation in lithium cobalt oxide positive electrode for lithium-ion batteries
Abstract Although the anionic activity in layered oxide positive electrodes is partially understood, the mechanism by which it induces internal crack propagation under high-voltage conditions remains unclear, severely limiting stable cycle life and available capacity. In this study, the mechanism underlying internal crack propagation is elucidated in LiCoO2 under harsh float-charge conditions at 60 °C and a potential of 4.6 V vs.
Changes and predictions of mumps incidence in China: a time series model with intervention approach
Information Type Letter to the Editor Information Epidemiology & Infection , Volume 154 , 2026 , e42 Creative Commons This is an Open Access article, distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives licence (http://creativecommons.org/licenses/by-nc-nd/4.0), which permits non-commercial re-use, distribution, and reproduction in any medium, provided that no alterations are made and the original article is properly cited.
Changes and predictions of mumps incidence in China: a time series model with intervention approach
We read with great interest the recent report in Epidemiology & Infection by Demirdag and colleagues showing that COVID-19 non-pharmaceutical interventions (NPIs) disrupted the usual epidemiology of respiratory viruses, with heterogeneous post-relaxation trajectories across pathogens and settings [Reference Bedir Demirdag1]. These observations raise the question of whether other vaccine-preventable infections experienced comparable pandemic-era declines and post-reopening rebounds.
An Efficient Self‐Supervised Seismic Data Reconstruction Method Based on Self‐Consistency Learning
Conflicts of Interest The authors declare no conflicts of interest. Data Availability Statement The data that support the findings of this study are available from the corresponding author upon reasonable request. References , , and . 2011. “A FaSt, Modified Parabolic Radon Transform.” Geophysics 76, no. 1: V11–V24. , , , and . 1992. “Image Coding Using Wavelet Transform.” IEEE Transactions on Image Processing 1: 205–220. , and . 2022.
Triazine-Based Porous Organic Cage-Coated Fiber for Cold-Assisted Headspace SPME-GC-MS: Ultratrace Detection of Semivolatile Liquid Crystal Monomers in Human Urine
Abstract Click to copy section linkSection link copied! Liquid crystal monomers (LCMs), which are key components of electronic displays, are emerging environmental contaminants owing to their persistence, bioaccumulation, and potential toxicity.
Association between circulating microRNAs and Chagas cardiomyopathy: A meta-analysis
Dear Editor: We have carefully reviewed the recent article by Michael et al. published in this journal, in which the authors identified serum microRNAs (miRNAs) associated with electrocardiographic abnormalities in patients with Chagas disease (CD).1 This study suggests that circulating miRNAs may serve as biomarkers for Chagas cardiomyopathy (CCC), a finding that has aroused our keen interest.
KOSLM: A Kalman-Optimal Hybrid State-Space Memory Network for Long-Term Time Series Forecasting
Submitted: 23 October 2025 You are already at the latest version Subscription Notify me about updates to this article or when a peer-reviewed version is published. This version is not peer-reviewed.
Zwitterionic Brush‐Grafted Interfacial Bio‐Lubricant Evades Complement C3‐Mediated Macrophage Phagocytosis for Osteoarthritis Therapy
Conflict of Interest The authors declare no conflict of interest. Supporting Information Filename Description adma202501137-sup-0001-SuppMat.docx7.7 MB Supporting Information References 1a) , , , Nat. Rev. Rheumatol. 2021, 17, 47; b) , Lancet 2018, 391, 1985. 2, , Lancet 2019, 393, 1745. 3a) , , , JAMA 2021, 325, 568; b) , , , Nat. Rev. Rheumatol. 2014, 10, 437. 4, , , , Nat. Rev. Rheumatol. 2019, 15, 355. 5a) , , , , , , , , , , , , , , Adv. Sci. 2023, 10, 2207490; b) , , , , , , , , , , , , , , Adv. Mater.
Comparative Analysis of Microscopic Pore Throat Heterogeneity in the Chang 6 Tight Sandstone Reservoir: Implications for Production Dynamics and Development Strategies in the Wuqi-Dingbian Region, Ordos Basin
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Molecular mechanisms of urate transport by the native human URAT1 and its inhibition by anti-gout drugs - Cell Discovery
Abstract Gout, a common and painful disease, stems from hyperuricemia, where elevated blood urate levels lead to urate crystal formation in joints and kidneys. The human urate transporter 1 (hURAT1) plays a critical role in urate homeostasis by facilitating urate reabsorption in the renal proximal tubule, making it a key target for gout therapy.
The Bio-Desulfurization of Cassiterite-Polymetallic Sulfide Ores Enhanced by a Consortium of Moderately Thermophilic Bacteria
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Enhanced Seafloor Topography Inversion Using an Attention Channel 1D Convolutional Network Based on Multiparameter Gravity Data: Case Study of the Mariana Trench
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Study on Self‐Healing Technology of Epoxy Resin for Insulator Core Rods
Conflicts of Interest The authors declare no conflicts of interest. Supporting Information Filename Description app56935-sup-0001-supinfo.docxWord 2007 document , 296.8 KB Data S1 Supporting Information. References 1, , , et al., “Natural Light-Triggered Microcapsules for Non-Contact and Autonomous Healing of Surface Damages on Insulating Materials,” Journal of Applied Polymer Science 141, no. 44 (2024): e56168.
Ideal comfort ellipses and comfort dynamics model for mitigating motion sickness in battery electric vehicle
Abstract Due to the rapid response and high torque output of the electric motor, drivers and passengers in battery electric vehicles are more prone to dizziness. This is particularly challenging for mitigating motion sickness, as acceleration performance conflicts with ride comfort. In this article, we develop ideal comfort ellipses based on various driving cycles, which show a comfort zone for driving.
Synergistic Catalysis by MgO Induced Acid‐Base Bifunctional Sites for Cross Condensation of HCHO and Acetaldehyde
Supporting Information As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors.
Multi-Label Feature Selection with Feature-Label Subgraph Association and Graph Representation Learning
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Natural light‐triggered microcapsules for non‐contact and autonomous healing of surface damages on insulating materials
Supporting Information Filename Description app56168-sup-0001-Supinfo.docxWord 2007 document , 498 KB Data S1. Supporting Information. REFERENCES 1, , , , , , Compos. Struct. 2021, 262, 113640. 2, , Constr. Build. Mater. 2020, 235, 117529. 3, , , , , Chem. Eng. J. 2019, 367, 169. 4, , , , , , , , Chem. Eng. J. 2024, 479, 147673. 5, , , , Adv. Funct. Mater. 2019, 29, 1900412. 6, , , , , , , , , , Adv. Mater. 2022, 34, 2201023. 7, , , , , , , , , , Chem. Eng. J. 2019, 369, 1150. 8, , , , , , , Prog. Mater. Sci.
A Study on the Efficient Degradation of Sulfur Hexafluoride by Pulsed Dielectric Barrier Discharge Synergistic Active Gas
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tRNA m1A modification regulate HSC maintenance and self-renewal via mTORC1 signaling - Nature Communications
Abstract Haematopoietic stem cells (HSCs) possess unique physiological adaptations to sustain blood cell production and cope with stress responses throughout life. To maintain these adaptations, HSCs rely on maintaining a tightly controlled protein translation rate. However, the mechanism of how HSCs regulate protein translation remains to be fully elucidated. In this study, we investigate the role of transfer RNA (tRNA) m1A58 ‘writer’ proteins TRMT6 and TRMT61A in regulating HSCs function.
In‐situ polymerization modified calcium sulfate whiskers and their application in PP composites research
REFERENCES 1, , , . Single-molecule study on the force-induced melting in syndiotactic polypropylene single crystals. Polymer. 2022; 256:125187. doi:10.1016/j.polymer.2022.125187 2, , . Mechanical behavior of calcium sulfate whisker-reinforced paraffin/gypsum composites. Constr Build Mater. 2021; 305:124795. doi:10.1016/j.conbuildmat.2021.124795 3, , , . Insights into the modification for improving the surface property of calcium sulfate whisker: experimental and DFT simulation study. Appl Surf Sci.
Spectral-Spatial-Sensorial Attention Network with Controllable Factors for Hyperspectral Image Classification
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Life-Long Aerobic Exercise is a Non-Pharmacological Approach for Inducing Autophagy and Delaying Muscle Atrophy in the Aging Population
在这里添加一些文本 RIS (ProCite, Reference Manager) BibTeX Life-Long Aerobic Exercise is a Non-Pharmacological Approach for Inducing Autophagy and Delaying Muscle Atrophy in the Aging Population Life-Long Aerobic Exercise is a Non-Pharmacological Approach for Inducing Autophagy and Delaying Muscle Atrophy in the Aging Population {{javascript:window.custom_author_en_index=0;}} {{article.zuoZhe_EN}} Author information History RIS Export {{article.zuoZheEn_L}}. {{article.title_en}}.
Technical system for mud loss analysis and diagnosis in drilling engineering to prevent reservoir damage
1 INTRODUCTION Mud loss, a problem relevant to geology, rock mechanics, non-Newtonian and multiphase flow mechanics, physical chemistry, material science, systems science, and other courses, remains an engineering problem of fundamental importance that has not yet been solved.
Variation of TaMyb10 and their function on grain color and pre‐harvest sprouting resistance of wheat
CONFLICT OF INTEREST The authors declared that they have no conflicts of interest in this work. Supporting Information Filename Description tpj16676-sup-0001-TableS1.xlsxExcel 2007 spreadsheet , 35.6 KB Table S1. SNPs, PAVs, color, GPs, and geographic distributions of Aegilops tauschii. tpj16676-sup-0002-TableS2.xlsxExcel 2007 spreadsheet , 77.5 KB Table S2. SNPs, PAVs, color, GPs, and geographic distributions of wheat. tpj16676-sup-0003-TableS3.xlsxExcel 2007 spreadsheet , 26.4 KB Table S3.
Accurate Identification Method of Small-Size Polymetallic Nodules Based on Seafloor Hyperspectral Data
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Refractive stability and timing of spectacle prescription following cataract surgery in myopic eyes
Rui Feng State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangdong Provincial Clinical Research Center for Ocular Diseases, Sun Yat-sen University, Guangzhou, China Department of Ophthalmology, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China Contribution: Conceptualization (equal), Data curation (equal), Formal analysis (equal),...
Facile and green synthesis of hydrophilic imprinted resin in deep eutectic solvents-water for specific molecular recognition of tumor biomarkers in complex biological matrices
Facile and green synthesis of hydrophilic imprinted resin in deep eutectic solvents-water for specific molecular recognition of tumor biomarkers in complex biological matrices Molecularly imprinted polymers (MIPs) are highly promising materials due to their excellent specific selectivity, chemical stability, and straightforward preparation process.
Regulated stepwise ESDPT mechanism associated with chalcogen substitutions for BDIBD derivatives
Regulated stepwise ESDPT mechanism associated with chalcogen substitutions for BDIBD derivatives Inspired by the brilliant photochemical and photophysical properties of organic molecule containing the chalcogenide substitutions that could be potentially applied across various disciplines, in this work, the effects of atomic electronegativity of chalcogen (O, S and Se) on hydrogen bond interactions and excited state proton transfer (ESPT) reaction are mainly focused.
Effects of Control Factors on Protein-Polyelectrolyte Complex Coacervation
Download Hi-Res ImageDownload to MS-PowerPointCite This:Biomacromolecules 2023, XXXX, XXX Terms & Conditions Most electronic Supporting Information files are available without a subscription to ACS Web Editions. Such files may be downloaded by article for research use (if there is a public use license linked to the relevant article, that license may permit other uses).
Investigation of Heat Accumulation in Femtosecond Laser Drilling of Carbon Fiber-Reinforced Polymer
1. Introduction Carbon fiber-reinforced polymer (CFRP) is composited with carbon fiber as the fiber reinforcement and epoxy resin as the matrix. It has wide applications in aerospace, the military industry, sports as well as the automotive industry [1,2,3] for its characteristics of low density, high stiffness, excellent corrosion and fatigue resistance. To facilitate the connection of CFRP components, plenty of through holes or blind holes need to be machined.
Experimental Optimization of High-Temperature-Resistant and Low Oil—Water Ratio High-Density Oil-Based Drilling Fluid
1. Introduction Shale gas is abundant around the world and is an important area of green energy development [1,2,3,4,5,6,7]. With the development of complex deep wells and unconventional horizontal wells, oil-based drilling fluid technologies face increasing challenges.
Efficient Dynamic Reconfigurable CNN Accelerator for Edge Intelligence Computing on FPGA
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Association Rule Mining through Combining Hybrid Water Wave Optimization Algorithm with Levy Flight
This is an early access version, the complete PDF, HTML, and XML versions will be available soon. Open AccessArticle by Qiyi He 1, Jin Tu 1, Zhiwei Ye 1,*, Mingwei Wang 1, Ye Cao 1, Xianjing Zhou 2 and Wanfang Bai 3 1 School of Computer Science, Hubei University of Technology, Wuhan 430068, China 2 Wuhan Zhuoer Information Technology Co., Ltd., Wuhan 430312, China 3 Xining Data Services Authority, Xining 810007, China * Author to whom correspondence should be addressed.
Characteristics of Surface Wave on the Unstable Interface in Gas Jet Forming
Abstract : The surface accuracy and quality of the mirror blank determine the performance of the optical mirror after coating; therefore, it is crucial to seek a simple and effective method for mirror blank processing. The gas jet forming provides a new idea, which employs a gas jet to impinge on a liquid pool, forms a specific curved surface and solidifies it.
The Variation of Surface Shape in the Gas Jet Forming
Abstract : This study investigated the the gas jet forming process for optical aspherical mirror blanks. The trend of the influence of the gas jet parameters on the surface shape of the mirror blanks was inferred by analysing the variation in the morphology of the gas jet stream. Based on the theoretical analysis, the inference was verified by numerical simulation.
Controlled Fabrication of Drug‐loaded Protein Nanoparticles via Flash Nanoprecipitation
Abstract Protein nanoparticles (NPs) are perspective vehicles for delivery of therapeutic agents. However, whether they will ever reach the stage of widespread application relies crucially on the development of reliable fabrication strategies and techniques. Herein, we report a continuous precipitation approach, namely flash nanoprecipitation (FNP) for efficient construction of drug-loaded protein NPs with regulated size and properties.
Antibody response and safety of COVID-19 vaccine in peritoneal dialysis patients
To the Editor: We read with interest a recent article reported by Ao G et al 1 Ao G. Li A. Wang Y. Tran C. Gao M. Chen M. The effect of SARS-CoV-2 double vaccination on the outcomes of hemodialysis patients with COVID-19: A meta-analysis. . The authors reported a meta-analysis describing the outcomes of hemodialysis patients infected with COVID-19 after SARS-CoV-2 double vaccination.
Efficacy and safety of Paxlovid for COVID-19:a meta-analysis
To the Editor: We read with interest a recent article reported by Wang Y et al 1 Wang Y. Chen X. Xiao W. Zhao D. Feng L. Rapid COVID-19 rebound in a severe COVID-19 patient during 20-day course of Paxlovid. . The authors reported a case of COVID-19 rebound in a severe COVID-19 patient during long term (20 days) treatment of Paxlovid. Paxlovid is a recommended treatment for mild-moderate COVID-19 and risk factors for severe disease.
Gels | Free Full-Text | Experimental Evaluation of the Rheological Properties and Influencing Factors of Gel Fracturing Fluid Mixed with CO2 for Shale Gas Reservoir Stimulation
This is an early access version, the complete PDF, HTML, and XML versions will be available soon.
Photothermal conversion performance and acid-induced aggregation of PLNP-Bi2S3 composite nanoplatforms
Photothermal conversion performance and acid-induced aggregation of PLNP-Bi2S3 composite nanoplatforms Yangqi Meng, Mingwei Wang, Yaqi Zhu, Shuai Wang, Jian Yang, Hancheng Zhu, Duanting Yan, Chunguang Liu, Changshan Xu and Yuxue Liu Abstract Poly(sodium 4-styrenesulfonate) (PSS) molecules modified PLNP-Bi2S3 composite nanoplatforms were constructed by using polyvinylpyrrolidone (PVP) modified Bi2S3 nanoparticles (~4.6 nm) as a photothermal agent and hexadecyl trimethyl ammonium bromide (CTAB)...
A simple and benign protocol for the synthesis of deep eutectic solvents-based hydrophilic molecularly imprinted resin in water for excellent selective molecular recognition in aqueous phase
A simple and benign protocol for the synthesis of deep eutectic solvents-based hydrophilic molecularly imprinted resin in water for excellent selective molecular recognition in aqueous phase Molecularly imprinted polymers (MIPs) are conventionally synthesized in organic solvents, resulting in poor compatibility with water and weak molecular recognition of targets in aqueous environments; hence, developing a green process to synthesize such MIPs would make the procedure more sustainable and...
HER2 amplification as a potential mechanism of acquired resistance to afatinib in an advanced non-small-cell lung cancer patient
1 Zhao S. Fang W. Pan H. et al. Conformational Landscapes of HER2 Exon 20 Insertions Explain Their Sensitivity to Kinase Inhibitors in Lung Adenocarcinoma. All patients with HER2-mutant lung cancer ultimately develop resistance to HER2-TKIs including afatinib. Several mechanisms of resistance had been described, HER2 mutations in exon 20, co-mutations, activation of alternative signaling pathways and histological transformation, etc. , 2 Fang W. Zhao S. Liang Y. et al.
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