Munir Pirmohamed on Muck Rack

Munir Pirmohamed

Liverpool
As seen in: Pharmacogenomics, National Institutes of Health, Color Research & Application, Nature, Wiley Online Library, British Pharmacological Society, Drug and Therapeutics Bulletin, The Lancet, The Pharmaceutical Journal, The Journal of Allergy & Clinical Immunology, European Journal of Obstetrics & Gynaecology and Reproductive Biology and
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Articles

Effects of fluoroquinolone antibiotics on extracellular matrix-related phenotypes in tendon cells

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By Akshay Anand, Keiko Sakai, David Dickens, Sachiko Minamiguchi, Naoya Asai, Riaz Akhtar, Munir Pirmohamed, Takao Sakai, Sadatoshi Tsuzuki, Ahmed Kazaili
| Nature Verified
Abstract Fluoroquinolones (FQ) are amongst the most widely prescribed antibiotics used to treat a wide range of infections because of their excellent gastrointestinal absorption, superior tissue penetration and broad-spectrum activity.
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Cardiovascular prescriber attitudes to pharmacogenomics: a survey by the ESC working group on cardiovascular pharmacotherapy

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By Emma F Magavern, Gianluigi Savarese, Claudio Borghi, Juan Tamargo, Péter Ferdinandy, John McDermott Verified, John Mcdermott, William Newman, Munir Pirmohamed, Mark Caulfield, Juan Carlos Kaski, G.-Andrei Dan, Dobramir Dobrev
| Nature Verified
Abstract The aim of this study was to elucidate cardiovascular prescriber access, uptake, and attitudes toward CYP2C19 and CYP2D6 genetic testing to guide prescribing of commonly used medications such as clopidogrel, antiarrhythmics, proton pump inhibitors, and antidepressants. A survey, designed in collaboration with the European Society of Cardiology (ESC) WG on Cardiovascular Pharmacotherapy and external experts was disseminated to ESC members using SurveyMonkey.
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UK Centre of Excellence in Regulatory Science and Innovation in Pharmacogenomics

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By Munir Pirmohamed, Cinzia Dello Russo
| British Pharmacological Society
Since the completion of the human genome project, there has been increasing evidence of how pharmacogenomic variation can affect drug dosing, drug efficacy and safety.1 However, the implementation of pharmacogenomics into clinical practice has been slow—many papers have highlighted the reasons for the slow uptake, and this has led to a greater emphasis on implementation projects.2 Of note is the PREPARE study, an open-label, multicentre, controlled, cluster-randomized crossover implementation...
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