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Articles by Ning Gu
The role of C-reactive protein to lymphocyte ratio and sleep duration in heart failure: exploring the mechanistic interplay and clinical implications
Abstract Heart failure (HF) is a progressive disease with complex pathogenesis involving inflammation, immune dysfunction, and metabolic abnormalities. Although C-reactive protein (CRP) is an established HF marker, the CRP-to-lymphocyte ratio (CLR) integrates inflammatory and immune responses. Sleep duration is also critical for cardiovascular health, but the joint impact of CLR and sleep on HF remains unclear.
Nature-inspired confined cascade enzyme nanoreactors for targeted atherosclerosis therapy - Signal Transduction and Targeted Therapy
Abstract Oxidative stress and excessive inflammatory responses are major drivers of atherosclerosis (AS) formation and progression. In this study, we report a nature-inspired nanoreactor (named USPB@SeDMSN@NM) with superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx) multienzymatic activities for targeted atherosclerosis therapy.
Microsimulation model to identify suboptimal recurrence detection in patients with colorectal cancer following the current standard of care
Microsimulation model to identify suboptimal recurrence detection in patients with colorectal cancer following the current standard of care Statistics from Altmetric.com Request Permissions If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.
Evaluating strategies for enhancing factors influencing sharing economy practices in the construction industry: A hybrid SWARA-WASPAS approach
1 INTRODUCTION In the era of digitalization, the sharing economy (SE) has transformed traditional resource consumption and business practices by introducing resource access over ownership to enhance resource utilization (Li et al., 2023). The SE concept aligns with the circular economy (CE) principles by promoting resource sharing and reducing waste while contributing to sustainability.
Delayed cord clamping in China: a cross-sectional survey of clinical practices and perceptions in Jiangsu Province
Discussion This study used anonymous questionnaires to collect information on the knowledge and practices of DCC among healthcare personnel in various maternity hospitals in Jiangsu Province. The results indicate that the awareness and implementation rates of DCC among obstetric healthcare personnel in Jiangsu are relatively high, though there are differences in practice details.
Neuroscientific methodologies in urban studies: a systematic review and new directions for evidence-based urban design and planning
ABSTRACT This paper presents a systematic review of research using EEG, fMRI, fNIRS, and eye-tracking to examine how these methods have been employed in urban studies under the umbrella term ‘neuro-urbanism’. The goal of neuroscientific urban research is to explore neural mechanisms that underlie cognitive and emotional processes evoked by exposure to public spaces.
Recent Advances in Room-Temperature Synthesis of Covalent Organic Frameworks
Recent Advances in Room-Temperature Synthesis of Covalent Organic Frameworks Covalent organic frameworks (COFs) have become a promising class of highly-crystalline polymers with layered stacking structures, ordered porous channels, and highly-tailorable structures. To date, most of COFs are synthesized via high-temperature solvothermal methods, which needs the complicated optimization including temperatures, solvent ratios, catalysts, reaction time and so on.
Association between the ratio of high-density lipoprotein cholesterol to apolipoprotein A-I and in-stent neoatherosclerosis: an optical coherence tomography study
Have a website account?Log In orRegister for exclusive website content. Home / Vol 15, No 1 (February 28, 2025) / Association between the ratio of high-density lipoprotein cholesterol to apolipoprotein A-I and in-stent neoatherosclero...
Improving Information Sharing in Offsite Construction (OSC): A Systematic Literature Review
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Microglia regulate neuronal activity via structural remodeling of astrocytes
Abstract Neuron-glia interactions play a central role in regulating synaptic transmission and neuronal excitability. Structural plasticity of astrocytes is associated with numerous physiological and pathological conditions, however, the mechanism underlying this process remains unknown. To examine the basis for structural astrocyte plasticity, we used the classic example of the loss of astrocytic processes that takes place in the hypothalamic magnocellular system during chronic high-salt intake.
Oxygen Nanobubbles Enhance ICG/Fe(III)-Mediated Dual-Modal Therapy To Induce Ferroptosis in Tumor Treatment
Biological and Medical Applications of Materials and InterfacesFebruary 18, 2025 * Li Yang Center of Interventional Radiology and Vascular Surgery, Department of Radiology, Nurturing Center of Jiangsu Province for State Laboratory of AI Imaging & Interventional Radiology (Southeast University), Basic Medicine Research and Innovation Center of Ministry of Education, Zhongda Hospital, Medical School, Southeast University, 87 Dingjiaqiao Road, Nanjing 210009, China *Email: yangli8288@seu.edu.cn...
A Multi-Faceted Analysis of Enablers and Barriers of Industrialised Building: Global Insights for the Australian Context
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Strategies for Enhancing Sharing Economy Practices Across Diverse Industries: A Systematic Review
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Exploring the Impact of Digital Technologies on Team Collaborative Design
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Machine Learning Constructed Based on Patient Plaque and Clinical Features for Predicting Stent Malapposition: A Retrospective Study
1 Background Coronary artery disease (CAD) remains one of the leading causes of mortality and morbidity worldwide [1]. Acute myocardial infarction (AMI) represents one of its most severe manifestations.
Association between periprocedural myocardial injury and neointimal characteristics in patients with in-stent restenosis: an optical coherence tomography study
Have a website account?Log In orRegister for exclusive website content. Home / Vol 14, No 1 (February 15, 2024) / Association between periprocedural myocardial injury and neointimal characteristics in patients with in-stent...
Efficacy of an enhanced recovery nursing plan as a rooming‐in practice for women with preeclampsia post‐cesarean section
1 INTRODUCTION Preeclampsia is an important cause of maternal and neonatal mortality, with a global prevalence of 3%−5% and a prevalence of about 4.2% in China.1 Hypertension, high levels of urinary protein, and multiple organ dysfunction often occur after 20 weeks of gestation. Among them, elevated levels of urinary protein and sustained high levels of blood pressure are signs of progressing preeclampsia.
Improved Resistive Switching Performance through Donor-Acceptor Structure Construction in Memristors Based on Covalent Organic Framework Films
Improved Resistive Switching Performance through Donor-Acceptor Structure Construction in Memristors Based on Covalent Organic Framework Films Covalent organic frameworks (COFs) with high crystallinity and tunable chemical structures have been promising materials for high-density organic memory and neuromorphic devices. However, the reports on regulating resistive switching performances via tailoring chemical structures of COF films are still limited.
The Story of Ferumoxytol: Synthesis Production, Current Clinical Applications and Therapeutic Potential
Ferumoxytol, approved by the U.S. Food and Drug Administration (FDA) in 2009, is one of intravenous iron oxide nanoparticle authorized for the treatment of iron deficiency in chronic kidney disease (CKD) and end-stage renal disease (ESRD). With its exceptional magnetic properties, catalytic activity, and immune activity, as well as good biocompatibility and safety, ferumoxytol has gained significant recognition in various biomedical diagnoses and treatments.
Design Decision-Making for Construction Waste Minimisation: A Systematic Literature Review
1. Introduction The construction industry has experienced significant growth and complexity, resulting in a rise in the amount of construction waste (CW) being generated [1]. This poses a considerable challenge for the industry, as the large volume of waste produced contributes to 30–40% of the total solid waste in the world [2,3].
Exploring International Perspective on Factors Affecting Urban Socio-Ecological Sustainability by Green Space Planning
1. Introduction Over the last century, rapid urbanisation has been causing a range of environmental challenges, such as urban overheating and air pollution [,], as well as the diminishing of green areas in cities []. The environmental fragility of cities and advanced urbanisation have motivated extensive research and policy efforts on sustainable urban development [,]. More recently, planners have been applying sustainability principles to urban planning [].
Stakeholders’ Perceptions of Digital Collaboration in Delivering a Mixed-Use Housing Development Project: A Case Study in Australia
This is an early access version, the complete PDF, HTML, and XML versions will be available soon. Open AccessArticle by 1, 2,*, 3, 3 and 1 1 UniSA Creative, University of South Australia, Adelaide, SA 5000, Australia 2 Future Building Initiative, Monash University, Melbourne, VIC 3145, Australia 3 CHSD—Centre for Healthy Sustainable Development, Torrens University, Sydney, NSW 2010, Australia * Author to whom correspondence should be addressed.
Study on ESIPT of salicylaldehyde derivative EQCN in DCM solvent
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Spatial transcriptomics reveal topological immune landscapes of Asian head and neck angiosarcoma - Communications Biology
Abstract Angiosarcomas are rare malignant tumors of the endothelium, arising commonly from the head and neck region (AS-HN) and recently associated with ultraviolet (UV) exposure and human herpesvirus-7 infection. We examined 81 cases of angiosarcomas, including 47 cases of AS-HN, integrating information from whole genome sequencing, gene expression profiling and spatial transcriptomics (10X Visium).
Volumetric Modular Construction Risks: A Comprehensive Review and Digital-Technology-Coupled Circular Mitigation Strategies
This is an early access version, the complete PDF, HTML, and XML versions will be available soon.
Recent Advances in the Application of Nanozymes in Amperometric Sensors: A Review
Abstract : Amperometric sensors evaluate current changes that occur as a result of redox reactions under constant applied potential. These changes in current intensity are stoichiometrically related to the concentration of analytes. Owing to their unique features, such as fast reaction velocity, high specificity, abundant existence in nature, and feasibility to be immobilized, enzymes are widely used by researchers to improve the performance of amperometric sensors.
Biometric Analysis in Design Cognition Studies: A Systematic Literature Review
Abstract : This study presents a systematic literature review on the utilisation of biometric analyses within the research area of design cognition. Design is a critical phase of many industries including architecture and construction, industrial design, engineering design, and many others. The development of design theories and methodologies to further understanding of designers’ cognitive design processes is thereby crucial.
Progress in the preparation of Prussian Blue-based nanomaterials for biomedical applications
Progress in the preparation of Prussian Blue-based nanomaterials for biomedical applications Kun Lu, Xiaoyang Zhu, Yan Li and Ning Gu Abstract Prussian blue (PB) is composed of the coordination network of Fe2+–C≡N–Fe3+ mixed valence state as a classic metal complex, which include C atom and Fe2+ (low spin), N atom and Fe3+ (high spin).
A Syntactical Spatio-Functional Analysis of Four Typical Historic Chinese Towns from a Heritage Tourism Perspective
1. Introduction With a history of over 3000 years, China encompasses more than 2000 historic towns and cities [1]. With Quanzhou: Emporium of the World in Song-Yuan China added to the World Heritage (WH) list in 2021, China so far has 56 recognised heritage properties including 38 cultural properties [2]. A growing concern on protecting these valuable towns has been raised and emphasised in the current literature.
Depletable peroxidase-like activity of Fe3O4 nanozymes accompanied with separate migration of electrons and iron ions - Nature Communications
Abstract As pioneering Fe3O4 nanozymes, their explicit peroxidase (POD)-like catalytic mechanism remains elusive. Although many studies have proposed surface Fe2+-induced Fenton-like reactions accounting for their POD-like activity, few have focused on the internal atomic changes and their contribution to the catalytic reaction.
Genetic variants in TKT and DERA in the nicotinamide adenine dinucleotide phosphate pathway predict melanoma survival
Highlights • Two variants ( TKT rs9864057 and DERA rs12297652) found to be associated with melanoma survival. • The risk genotypes were associated with survival of the patients in an allele dose-response manner. • Their risk alleles were associated with higher mRNA expression levels in the sun-exposed skin. Abstract Background Cutaneous melanoma (CM) is the most lethal type of skin cancers.
Introduction to Biosensors
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Regulations on cell therapy products in China: a brief history and current status
The authors have no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript. This includes employment, consultancies, honoraria, stock ownership or options, expert testimony, grants or patents received or pending, or royalties. No writing assistance was utilized in the production of this manuscript.
Catalytic Gold-Platinum Alloy Nanoparticles and a Novel Glucose Oxidase Mimic with Enhanced Activity and Selectivity Constructed by Molecular Imprinting
Catalytic Gold-Platinum Alloy Nanoparticles and a Novel Glucose Oxidase Mimic with Enhanced Activity and Selectivity Constructed by Molecular Imprinting Lin Fan, Doudou Lou, Haoan Wu, Yan Cui, Ning Gu and Yu Zhang Abstract Gold nanoparticles have received a great deal of interest, but also exhibit inherent disadvantages of limited catalytic efficiency and lacking selectivity.
Signal amplifying fluorescent nanoprobe and lateral flow assay for ultrasensitive detection of cardiac biomarker troponin I
Signal amplifying fluorescent nanoprobe and lateral flow assay for ultrasensitive detection of cardiac biomarker troponin I As a kind of biosensor which is easy to produce and use, lateral flow immunoassay (LFIA) has been favored by people for a long time and applied in various fields such as disease diagnosis, drug testing and environment monitoring.
Differential interactions of missing in metastasis and insulin receptor tyrosine kinase substrate with RAB proteins in endocytosis of CXCR4
Lushen Li1, Shaneen S.
Frontiers | Case Study of a Digital Augmented Reality Intervention for Autism in School Classrooms: Associated With Improved Social Communication, Cognition, and Motivation via Educator and Parent Assessment | Education
Introduction Autism Spectrum Disorder (ASD) is a childhood onset developmental condition with a rapidly increasing prevalence, and is present in 1 in 59 school-aged children (Baio et al., 2018). Impairment in social communication is the hallmark feature of ASD, encompassing perseverative deficits in verbal and non-verbal communication (American Psychiatric Association, 2013).
A glucose-activatable trimodal glucometer self-assembled from glucose oxidase and MnO2 nanosheets for diabetes monitoring
Daily monitoring of blood glucose is of great importance for the treatment of diabetes mellitus. Herein, we presented an ensemble glucometer with a sandwiched structure formed by the spontaneouse entrapment of glucose oxidase (GOD) onto manganese dioxide nanosheets (MnO2 NSs) via hydrophobic effect andhydrogen bond interaction. Among of hybrid glucometer, the ultrathin MnO2 NSs acts as an enzyme nanosupport and target-activated signal transduction.
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