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Articles by Ran Ding
Perioperative blood staging based on personalized ctDNA assay for recurrence prediction in NSCLC
Abstract Circulating tumour DNA (ctDNA) is a valuable biomarker for relapse monitoring. However, current personalized approaches are unable to detect emerging clones, and perioperative ctDNA dynamics remain to be defined. We prospectively validated Hi-SECURE, a tumour-informed MRD assay, in 132 NSCLC patients (POEM cohort). Analytical performance was benchmarked against reference standards and a fixed 158-gene panel. A perioperative blood (PB) staging system was proposed and externally validated.
Tunnel field-effect transistors exhibiting performance beyond the Boltzmann thermionic limit
Editor’s summary Abstract Supplementary Materials References and Notes Information & Authors Metrics & Citations Check Access References Figures Tables Media Share This article has 0 eLetter . Editor’s summary A field-effect transistor (FET) based on tunneling between two-dimensional layers of p-type bismuth and n-type indium selenide can lower driving voltage and power consumption. Wu et al.
Copper-Catalyzed Intermolecular Carbosulfonylation of Alkynes to Access Functionalized Eight-Membered Tetrahydroazocines Click to copy article link Article link copied!
Cite Jump to ExpandCollapse ArticleJuly 5, 2026 Copper-Catalyzed Intermolecular Carbosulfonylation of Alkynes to Access Functionalized Eight-Membered Tetrahydroazocines Click to copy article linkArticle link copied! Ran Ding* Ran Ding College of Chemistry and Materials Engineering, Anhui Science and Technology University, Bengbu 233000, Anhui, P. R. China Anhui Province Quartzs and Purification and Photovoltaic Glass Engineering Research Center, Chuzhou 233100, P. R.
Association of Central Acetabular Osteophytes With Microinstability and Increased Combined Anteversion in Borderline Dysplasia Hips
Abstract References Get access More Cite Share options Information, rights and permissions Metrics and citations Abstract Background: Central acetabular osteophytes (CAOs) have been implicated in abnormal hip biomechanics. However, their relationship with microinstability in borderline developmental dysplasia of the hip (BDDH) is unclear.
CD147-positive migrasome macropinocytosis promotes HCC sorafenib resistance via inducing vasculogenic mimicry triggered by PI3K/AKT/TWIST1 signaling
Abstract Sorafenib is a widely used targeting drug for hepatocellular carcinoma (HCC) patients; however, sorafenib resistance poses a significant clinical challenge. Hypoxia and extracellular vesicles (EVs) induce vasculogenic mimicry (VM) which is linked to sorafenib resistance in HCC. Migrasomes (Migs), the newly discovered large EVs, foster HCC malignant phenotypes by facilitating the intercellular transfer of functional molecules.
Stacking Fault Energy Engineering as the Pathway to Materials With Exceptional Performance
1 Introduction The motion and interaction of defects largely dictate how crystals respond to external stimuli [1-6]. Among them, a stacking fault (SF) is one of the simplest planar defects. It is a thin region where the normal atomic layer sequence is locally misplaced [7-10]. The stacking fault energy (SFE) is the energy penalty per unit area for creating this misplaced stacking [11, 12].
A robotic patch-clamp system with real-time localization and phase-synchronized capture of dynamic in vivo cells using micropipette resistance modelling
Abstract In vivo patch clamp is the gold standard for probing neuronal function in the intact brain of living animals through recordings of membrane potentials and picoampere-level ionic currents. To achieve this, the recording micropipette must first capture a target neuron and form a gigaohm-scale seal (gigaseal) at the cell membrane. This requires real-time localization of in vivo neurons whose positions fluctuate with physiological activity (e.g., respiration and vascular pulsation).
Trifunctional Single-Crystalline Layer for Efficient, Stable, and Simplified White Organic Light-Emitting Diodes
Conflicts of Interest The authors declare no conflicts of interest. Data Availability Statement The data that support the findings of this study are available from the corresponding author upon reasonable request. Supporting Information Filename Description lpor71236-sup-0001-SuppMat.docx3.3 MB Supporting File: lpor71236-sup-0001-SuppMat.docx.
Mediating effect of coping style between family resilience and demoralization in patients with decompensated cirrhosis
Abstract This study aimed to examine the relationship between family resilience and demoralization syndrome (DS) in patients with decompensated cirrhosis and explore the mediating role of coping styles in this association.
Synergistic photothermal therapy of esophageal cancer using Pt@MOF@PSs nanozymes
1 Introduction Esophageal cancer (EC) arises from the epithelial lining of the esophagus, most commonly presenting as squamous cell carcinoma or adenocarcinoma (Luo et al., 2021; Kato et al., 2021). It is one of the most common cancers worldwide, characterized by a high incidence and mortality rates and poor prognosis.
Elevated CHI3L1 as a Potential Biomarker of Cognitive Dysfunction in Anti‐NMDAR Encephalitis: Evidence From Clinical Results and Mice Model
CFA Complete Freund's Adjuvant CHI3L1 Chitinase-3-like protein 1 CNS Central Nervous System CSF Cerebrospinal Fluids DEP Differentially Expressed Protein mRS modified Rankin Scale NMDAR N-methyl-D-aspartate receptor NSC Neural Stem Cell 1 Introduction Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is the most common form of autoimmune encephalitis [1, 2].
3D-CovDiffusion: 3D-Aware Diffusion Policy for Coverage Path Planning
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Illuminating Black Hole Shadows with Dark Matter Annihilation
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Interlayer pillaring influences the octahedral tilting and electrochemical capacity of tungsten oxides
Interlayer pillaring influences the octahedral tilting and electrochemical capacity of tungsten oxides† One strategy to tune the electrochemical properties of layered inorganic materials for energy storage and conversion is to introduce molecular organic pillars. We investigated how pillaring tungsten oxides with alkylammonium cations influences their physical and electrochemical properties relative to the non-pillared host.
Multi-Omics Characterization of Genome-Wide Abnormal DNA Methylation Reveals FGF5 as a Diagnosis of Nasopharyngeal Carcinoma Recurrence After Radiotherapy
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Integrated genomic analysis of lung squamous cell carcinoma subtypes c
Back to Journals » OncoTargets and Therapy » Volume 18 Authors Wang Y, Wang S, Ding R , Zhang Z, Kong J, Xie T, Xu B, Fu L, Zhang E Received 21 November 2024 Accepted for publication 28 March 2025 Published 11 April 2025 Volume 2025:18 Pages 521—537 DOI https://doi.org/10.2147/OTT.S503419 Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 2 Editor who approved publication: Prof.
The Impact of Ultra-Low Temperature Quenching Treatment on the Pore Structure of Natural Quartz Sand
Preprint Article Version 1 This version is not peer-reviewed Version 1 : Received: 10 October 2024 / Approved: 10 October 2024 / Online: 10 October 2024 (12:55:56 CEST) Guo, Y.; Cheng, N.; Ding, R.; Chen, J.; Shu, L.; Xu, W.; Shi, G. The Impact of Ultra-Low Temperature Quenching Treatment on the Pore Structure of Natural Quartz Sand. Preprints 2024, 2024100805. https://doi.org/10.20944/preprints202410.0805.v1 Guo, Y.; Cheng, N.; Ding, R.; Chen, J.; Shu, L.; Xu, W.; Shi, G.
Buildings | Free Full-Text | Experimental and Numerical Study on the Performance of Steel-Coarse Aggregate Reactive Powder Concrete Composite Beams with Uplift-Restricted and Slip-Permitted Connectors under Negative Bending Moment
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The RNF214-TEAD-YAP signaling axis promotes hepatocellular carcinoma progression via TEAD ubiquitylation - Nature Communications
Abstract RNF214 is an understudied ubiquitin ligase with little knowledge of its biological functions or protein substrates. Here we show that the TEAD transcription factors in the Hippo pathway are substrates of RNF214. RNF214 induces non-proteolytic ubiquitylation at a conserved lysine residue of TEADs, enhances interactions between TEADs and YAP, and promotes transactivation of the downstream genes of the Hippo signaling.
Search for R-Parity-Violation-Induced Charged Lepton Flavor Violation at Future Lepton Colliders
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Mechanochemical reduction of alkyl and aryl halides using mesoporous zinc oxide
Mechanochemical reduction of alkyl and aryl halides using mesoporous zinc oxide† In this study, we propose a mechanochemical approach that combines mesoporous ZnO (m-ZnO) as a mechanoredox catalyst and silane-mediated atom transfer chemistry to achieve efficient hydrodehalogenation of organic halides. The reaction can be conducted under mild conditions without the use of a large amount of organic solvent.
Controllable synthesis of NiCo2O4 nanoparticles supported on MnO2 nanowires with excellent oxidase-mimicking performance
Controllable synthesis of NiCo2O4 nanoparticles supported on MnO2 nanowires with excellent oxidase-mimicking performance One dimensional(1D) hierarchical structure with hybrid components is extremely attractive for their integrated properties and synergistic effect in catalytic application.
Direct observation of intrinsic room-temperature ferroelectricity in 2D layered CuCrP2S6 - Nature Communications
Abstract Multiferroic materials have ignited enormous interest owing to their co-existence of ferroelectricity and ferromagnetism, which hold substantial promise for advanced device applications. However, the size effect, dangling bonds, and interface effect in traditional multiferroics severely hinder their potential in nanoscale device applications.
Autoimmune encephalitis antibody profiles and clinical characteristics of children with suspected autoimmune encephalitis
Supporting Information Filename Description dmcn15762-sup-0001-FigureS1.tifTIFF image, 4.2 MB Figure S1: Flow chart. dmcn15762-sup-0002-FigureS2.docxWord 2007 document , 1.2 MB Figure S2: Missing values visualization. dmcn15762-sup-0003-FigureS3.docxWord 2007 document , 1.1 MB Figure S3: Upset plots for missing values.
Melanin-Inspired Composite Materials: From Nanoarchitectonics to Applications
Download Hi-Res ImageDownload to MS-PowerPointCite This:ACS Appl. Mater. Interfaces 2024, XXXX, XXX Terms & Conditions Most electronic Supporting Information files are available without a subscription to ACS Web Editions. Such files may be downloaded by article for research use (if there is a public use license linked to the relevant article, that license may permit other uses).
Association between the Healthy Eating Index-2015 and Developmental Disabilities in Children: A Cross-Sectional Analysis
1. Introduction Developmental disabilities (DDs) are referred to as a cluster of life-long conditions characterized by difficulties in acquiring and executing specific intellectual, physical, linguistic, or social functions, based on the 10th edition of the International Classification of Diseases (ICD).
Copper Catalyst-Promoted Regioselective Multicomponent Cascade Cyclization of 3-Aza-1,5-enynes with Sulfur Dioxide and Cycloketone Oxime Esters to Access Cyanoalkylsulfonylated 1,2-Dihydropyridines
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Copper Catalyst-Promoted Regioselective Multicomponent Cascade Cyclization of 3-Aza-1,5-enynes with Sulfur Dioxide and Cycloketone Oxime Esters to Access Cyanoalkylsulfonylated 1,2-Dihydropyridines
Tuesday, January 23, 2024 Please be aware that pubs.acs.org is undergoing maintenance that may have an impact on your experience. During this time, you may not be able to access certain features like purchasing single articles, saving searches, modifying your e-Alert preferences, or accessing Librarian administrative functions. We appreciate your patience as we continue to improve the ACS Publications platform.
Photoredox-Catalyzed Synthesis of 3-Sulfonylated Pyrrolin-2-ones via a Regioselective Tandem Sulfonylation Cyclization of 1,5-Dienes
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Dietary Intake of Flavonoids Associated with Sleep Problems: An Analysis of Data from the National Health and Nutrition Examination Survey, 2007–2010
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Identification of cytokine predominant immunosuppressive class and prognostic risk signatures in glioma
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Accelerated pyro-catalytic hydrogen production enabled by plasmonic local heating of Au on pyroelectric BaTiO3 nanoparticles - Nature Communications
Abstract The greatest challenge that limits the application of pyro-catalytic materials is the lack of highly frequent thermal cycling due to the enormous heat capacity of ambient environment, resulting in low pyro-catalytic efficiency.
Catalyst-free benzylic C(sp3)-H cross-coupling with organotrifluoroborates enabled by electrochemistry
Catalyst-free benzylic C(sp3)-H cross-coupling with organotrifluoroborates enabled by electrochemistry Chao Li, Ran Ding, Heng-Yi Guo, Shuang Xia, Lei Shu, Pei-Long Wang and Hongji Li Abstract Herein, we report a rare catalyst-free electrochemical cross-coupling of benzylic C–H bonds with organotrifluoroborates, which readily proceeds at room temperature and provide a unique protocol for forging C(sp3)–C(sp3) and C(sp3)–C(sp2) bonds.
Modulating Built‐In Electric Field via Variable Oxygen Affinity for Robust Hydrogen Evolution Reaction in Neutral Media
Research Article Lingling Zhai, Lingling Zhai Department of Applied Physics, The Hong Kong Polytechnic University, Hung Hom, Hong Kong, P. R. China Search for more papers by this author Xiaojie She, Xiaojie She Department of Applied Physics, The Hong Kong Polytechnic University, Hung Hom, Hong Kong, P. R. China Search for more papers by this author Lyuchao Zhuang, Lyuchao Zhuang Department of Applied Physics, The Hong Kong Polytechnic University, Hung Hom, Hong Kong, P. R.
Multifunctional Optoelectronic Synapse Based on Ferroelectric Van der Waals Heterostructure for Emulating the Entire Human Visual System
Research Article Feng Guo, Department of Applied Physics, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, 999077 P. R. China Search for more papers by this author Menglin Song, Department of Applied Physics, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, 999077 P. R. China Search for more papers by this author Man-Chung Wong, Department of Applied Physics, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, 999077 P. R.
Chemical heterogeneity enhances hydrogen resistance in high-strength steels
Abstract The antagonism between strength and resistance to hydrogen embrittlement in metallic materials is an intrinsic obstacle to the design of lightweight yet reliable structural components operated in hydrogen-containing environments. Economical and scalable microstructural solutions to this challenge must be found.
Large-scale growth of few-layer two-dimensional black phosphorus
References 1. Li, L. et al. Black phosphorus field-effect transistors. Nat. Nanotechnol. 9, 372–377 (2014). CAS Article Google Scholar 2. Qiao, J., Kong, X., Hu, Z. X., Yang, F. & Ji, W. High-mobility transport anisotropy and linear dichroism in few-layer black phosphorus. Nat. Commun. 5, 4475 (2014). CAS Article Google Scholar 3. Xia, F., Wang, H. & Jia, Y. Rediscovering black phosphorus as an anisotropic layered material for optoelectronics and electronics. Nat. Commun. 5, 4458 (2014). CAS Article Google Scholar 4.
The relationship between platelet indices and patent ductus arteriosus in preterm infants: a systematic review and meta-analysis
Abstract Patent ductus arteriosus (PDA), one of the most common disorders in newborns, is associated with many complications in premature infants such as respiratory distress syndrome (RDS) and bronchopulmonary dysplasia (BPD). However, the diagnosis of hemodynamically significant patent ductus arteriosus (hsPDA) is still an ongoing debate. The relationship between platelet parameters and hsPDA has been explored in many studies over the last decade, but there is still no definite conclusion.
Chemical boundary engineering: A new route toward lean, ultrastrong yet ductile steels
Abstract For decades, grain boundary engineering has proven to be one of the most effective approaches for tailoring the mechanical properties of metallic materials, although there are limits to the fineness and types of microstructures achievable, due to the rapid increase in grain size once being exposed to thermal loads (low thermal stability of crystallographic boundaries).
Activation of C-H, N-H, and O-H Bonds via Proton-Coupled Electron Transfer to a Mn(III) Complex of Redox-Noninnocent Octaazacyclotetradecadiene, a Catenated-Nitrogen Macrocyclic Ligand - Journal of the American Chemical Society (ACS Publications)
Shivaiah Vaddypally† , Warren Tomlinson‡, Owen T. O’Sullivan†, Ran Ding† , Megan M. Van Vliet† , Bradford B. Wayland†, Joseph P. Hooper*‡ , and Michael J. Zdilla*† † Department of Chemistry, Temple University, 1901 North 13th Street, Philadelphia, Pennsylvania 19122 , United States ‡ Department of Physics, Naval Postgraduate School, 833 Dyer Road, Monterey, California 93943 , United States J. Am. Chem.
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