Ric N. Price on Muck Rack

Ric N. Price

Darwin, Oxford
As seen in: Nature, MDPI, Trials Journal, Cell Press, The Lancet
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Articles

FocaL mass drug administration for Plasmodium vivax malaria elimination (FLAME): study protocol for an open-label cluster randomized controlled trial in Peru | Trials | Full Text

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By Soto Calle, Altamirano Quiroz, Rodriquez Ferruci, Carrasco Escobar, Sydney R. Fine, Paulo Manrique, Xue Wu, Gabriel Escobar Verified, Jade Benjamin-Chung, Adam Bennett, Sarah Auburn, Ric N. Price, Bryan Greenhouse, J. Baird, Gonzalo J Domingo, Veronica Soto Calle, Astrid Altamirano Quiroz, Hugo Rodriquez Ferruci
| Trials Journal Verified
The SPIRIT (Standard Protocol Items: Recommendations for Interventional Trials) recommendations were referenced in developing this protocol [28]. Figure 1 demonstrates the overall study communities’ involvement in the FLAME trial per SPIRIT guidelines. Flowchart demonstrating the involvement of FLAME communities throughout the trial per SPIRIT guidelines. Vector control includes the distribution of insecticide-treated nets (ITNs) and the use of indoor residual spraying (IRS).
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Microhaplotype deep sequencing assays to capture Plasmodium vivax infection lineages - Nature Communications

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By Edwin Sutanto, Ashley Osborne, Ernest Diez Benavente, Sasha V. Siegel, Richard Pearson, Roberto Amato, Hoang Nguyen Verified, Hoàng Nguyên, Hoàng Nguyễn Verified, Ashenafi Assefa, Awab Ghulam Rahim, Mohammad Shafiul Alam, Diego F. Echeverry, Matthew J Grigg, Nicholas White, Dominic P Kwiatkowski, Aimee Taylor, Daniel E. Neafsey, Ric N. Price, Dagimawie Tadesse Abate
| Nature Verified
Abstract Plasmodium vivax elimination is challenged by dormant liver stages (hypnozoites) that can reactivate months after initial infection resulting in relapses. Relapsing infections confound antimalarial clinical efficacy trials due to the inability to distinguish between recurrences arising from blood-stage treatment failure (recrudescence), reinfection or relapse.
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Lineage-informative microhaplotypes for recurrence classification and spatio-temporal surveillance of Plasmodium vivax malaria parasites - Nature Communications

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By Sasha V. Siegel, Hidayat Trimarsanto, Roberto Amato, Edwin Sutanto, James Watson, Mallika Imwong, Ashenafi Assefa, Julian C. Rayner, Ric N. Price, Mariana Kleinecke, Awab Ghulam Rahim
| Nature Verified
Abstract Challenges in classifying recurrent Plasmodium vivax infections constrain surveillance of antimalarial efficacy and transmission. Recurrent infections may arise from activation of dormant liver stages (relapse), blood-stage treatment failure (recrudescence) or reinfection. Molecular inference of familial relatedness (identity-by-descent or IBD) can help resolve the probable origin of recurrences. As whole genome sequencing of P.
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