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Mapping the human chemical exposome for public health
Pollution represents a silent global public health crisis, contributing to an estimated 9 million premature deaths annually1. It is likely that this figure underestimates the true burden, as only a fraction of the thousands of chemicals in global commerce have been adequately tested for safety or measured in humans, either individually or even more rarely as mixtures.
Per- and polyfluoroalkyl substances as persistent pollutants with metabolic and endocrine-disrupting impacts
Highlights Per- and polyfluoroalkyl substances (PFASs) have pleiotropic effects on human health, linked to the endocrine system. PFASs have been associated with male and female reproductive disorders, such as: infertility, endometriosis, and polycystic ovary syndrome. Various conditions in early childhood are linked to exposure to PFASs in utero. PFASs have been found to disrupt thyroid function and hormone synthesis. Dyslipidemia is an important metabolic disorder associated with PFAS exposure.
Que faut-il savoir sur les PFAS, ces " polluants éternels " ?
_Découvertes dans les années 1940, les PFAS constituent depuis quelques années une source de préoccupation croissante, en raison de leurs effets sur la santé. Alors qu’une proposition de loi visant à les interdire est en discussion en France, les États-Unis ont annoncé le 10 avril établir des seuils limites pour l’eau courante, une première dans ce pays.
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