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Stephanie Bourgeois on Muck Rack

Stephanie Bourgeois

As seen in: Nature, The Conversation, Science Magazine, BioRxiv, Food52, Cell Press, AllAfrica.com Français, Connecticut Post, Stamford Advocate, Greenwich Time and
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Articles

The genomic impact of population connectivity and decline in Africa’s elephants

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By Yasuko Ishida, Genís Garcia-Erill, Laura Bertola, Cindy G Santander, Xiaodong Liu, Anubhab Khan, Lauren M. Hennelly, Renzo F. Balboa, Long Lin, Malthe S. Rasmussen, Xi Wang, Mikkel Schubert, Amal Al-Chaer, Sylwia Urbaniak, Kan Nobuta, Sasha Treadup, Karine A. Viaud-Martinez, Alida de Flamingh, Ripan S. Malhi, Savanah Bird, Nelson Ting, Mrinalini Erkenswick Watsa, Martin N. Tchamba, Stephanie Bourgeois, Chris Thouless, Iain Douglas-Hamilton, George Wittemyer, Peter de Groot, Vincent B. Muwanika, Charles Masembe, Nicholas Georgiadis, Christina Hvilsom, Rasmus Heller, Hans Redlef Siegismund, Alfred L. Roca
| Nature Verified
Abstract African elephants are keystone species facing severe declines due to the ivory trade and habitat loss. To investigate the genomic consequences, we analyze 232 high-coverage genomes from 17 African countries in the first continent-wide genomic analysis treating savanna (Loxodonta africana) and forest (L. cyclotis) elephants as distinct species.
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Iron deficiency induces maturation-dependent loss of pancreatic β-cells - Nature Communications

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By Annelore Van Mulders, Sophie Coenen, Stephanie Bourgeois, Xiaoyan Yi, Yue Tong, Gunter Leuckx, Yves Heremans, Julie Pierreux, Toshiaki Sawatani, Chiara Vinci, Gamze Bölükbaşı Ateş, Ann MacLean Massie, Françoise Carlotti, Eelco de Koning, Thomas Mandrup-Poulsen, Steven Goderis, Bart Ghesquière, Raphaël Scharfmann, Miriam Cnop, Willem Staels, Lien Willems, Laure Degroote, Clara Zelinsky, Nico De Leu
| Nature Verified
Abstract Pancreatic β-cells maintain glucose homeostasis by secreting insulin in response to rising blood glucose, a process fueled by mitochondrial ATP production. Iron, a core cofactor in the electron transport chain, is essential for this metabolic coupling. While the cytotoxic effects of iron overload are well known, the role of iron sufficiency during β-cell development remains unclear. Here, we identify a maturation-dependent requirement for iron in mouse and human β-cells.
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ER stress relief drives beta cell proliferation

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By Stephanie Bourgeois, Gunter Leuckx, Annelore Van Mulders, Yves Heremans
| BioRxiv
Abstract Regenerating endogenous pancreatic beta cells is a potentially curative yet currently elusive strategy for diabetes therapy. Mimicking the microenvironment of the developing pancreas and leveraging vascular signals that support pancreatic endocrinogenesis may promote beta cell regeneration.
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