Ting Pan
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Articles by Ting Pan
Computer Science > Computer Vision and Pattern Recognition
The annotation used to select a segmentation threshold is part of the evaluation protocol, yet its effect is easily conflated with model quality. We examine this choice for retinal vessel segmentation using all 28 CHASE DB1 images and both human annotations. A fixed seven-fold protocol keeps both eyes of each of the 14 subjects together.
Computer Science > Computer Vision and Pattern Recognition
Contour initialization and numerical stopping can jointly affect the evaluation of active-contour segmentation. We examine their interaction using the open-source scikit-image Chan-Vese implementation on a resized ISIC 2017 mirror. A fixed development set of 100 images selects a common input channel; all 600 images in the repository's held-out partition are then evaluated.
Correction: Methicillin-resistant Staphylococcus aureus (MRSA) infection in hospitalized patients is dominated by community-acquired strains: genomic epidemiological evidence
The affiliations are listed out of order.
Author Correction: Targeting liquid–liquid phase separation of SARS-CoV-2 nucleocapsid protein promotes innate antiviral immunity by elevating MAVS activity
Correction to: Nature Cell Biology https://doi.org/10.1038/s41556-021-00710-0, published online 8 July 2021. In the version of this article initially published, in Fig. 1j, the image shown for the d_IDR2 representation was a mistaken image; in Extended Data Fig. 5, second row from the top, three incorrect image panels were included; in Extended Data Fig. 6a and associated Source Data, an incorrect SDD AGE panel was presented. In the Source Data for Figs.
Retinoic Acid–Functionalized Lipid Nanoparticles Reprogram Splenic Immunity for Potent mRNA Cancer Vaccination
Conflicts of Interest The authors declare no conflicts of interest. Data Availability Statement The data that support the findings of this study are available from the corresponding author upon reasonable request. Supporting Information Filename Description adfm77225-sup-0001-SuppMat.docx3.4 MB Supporting File: adfm77225-sup-0001-SuppMat.docx.
Stretchable and self-healing copper–iodide scintillator for conformal X-ray imaging and wearable radiation alerting
Abstract Flexible X-ray scintillators are critical for next-generation conformal imaging and wearable radiation monitoring, yet their development is hindered by the persistent trade-offs among particle dispersion, scintillation efficiency, and mechanical robustness in conventional composite designs.
Reconfigurable Metasurface with Reflective and Transmissive Polarization Conversion Capabilities Based on Vanadium Dioxide
Abstract This study proposes a reconfigurable metasurface based on the phase-changing characteristics of vanadium dioxide (VO2), enabling dynamic switching between reflective and transmissive polarization conversions by tuning VO2 conductivity. The unit cell comprises Au-VO2 alternating gratings (AVAG), a silicon dioxide (SiO2) dielectric layer, and four inverted “L”-shaped metallic structures (FILS).
All-two-dimensional, ion-gating synaptic transistors for high-temperature and ultralow-energy-consumption neuromorphic applications
Abstract INTRODUCTION RESULTS DISCUSSION MATERIALS AND METHODS Acknowledgments Supplementary Materials REFERENCES Information & Authors Metrics & Citations View Options References Figures Tables Media Share Abstract High-temperature intelligent devices operating above 125°C are crucial for applications where cooling is insufficient or impossible.
Author Correction: Targeting a key disulfide linkage to regulate RIG-I condensation and cytosolic RNA-sensing
Correction to: Nature Cell Biology https://doi.org/10.1038/s41556-025-01646-5, published online 14 April 2025. In the version of this article initially published, due to a figure preparation error, a high-exposure scan of the IRF3 blot intended for Fig. 7i was mistakenly used in Fig. 8g. In the statistical Source Data for Fig. 3a and 3m, values in the +dsRNA size-exclusion chromatography column of Fig. 3a were inadvertently extracted from unrelated datasets. In the Source Data for Fig.
Paradoxical role of the mesocorticolimbic Netrin1-DCC pathway in social competition and vulnerability to methamphetamine abuse during adolescence
Abstract Social competition exerts a diverse set of influences on neural development and behavior during adolescence and yet the precise underlying molecular mechanisms remain poorly understood. Here, we demonstrate that individual rodents that rank lower in social hierarchies are more vulnerable to drug abuse. Proteomic analysis revealed a crucial role of the mesocorticolimbic netrin-1/DCC/UNC5 pathway within the nucleus accumbens (NAc) in mediating the impact of social competition.
HE4 drives PD-L1 expression in myeloid cells via IFN-γR-JAK-STAT3 signaling to promote tumor immune evasion
ArticleOnline now102691Open access Affiliations & Notes 1The Key Laboratory for Human Disease Gene Study of Sichuan Province and the Department of Laboratory Medicine, Sichuan Provincial People’s Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu 610072, China 2Research Unit for Blindness Prevention of the Chinese Academy of Medical Sciences, Sichuan Academy of Medical Sciences and Sichuan Provincial People’s Hospital, Chengdu 610072, China 3School...
PLOS Neglected Tropical Diseases
Loading metrics Open Access Peer-reviewed Research Article ? This is an uncorrected proof. Citation: Zhang P, Ma X, Pan T, Dang J, Pan D, Chen M, et al. (2026) Socioeconomic drivers of human Brucellosis in Ningxia, China: A one health and spatiotemporal analysis for targeted intervention. PLoS Negl Trop Dis 20(3): e0014124.
Innovative fusion models: elevating preoperative gross ETE prediction in thyroid cancer patients
Abstract The intratumoral and peritumoral architectural heterogeneities of papillary thyroid carcinoma (PTC) are important in preoperative prediction of gross extrathyroidal extension (Gross ETE). This study systematically evaluated and compared the predictive efficacies of deep learning, radiomics, and their combined approach (Deep Learning-Radiomics, DLR) in predicting Gross ETE in PTC patients using ultrasound imaging.
ODC1 Polyamine Metabolism Drives Prostate Cancer via AKT and Splicing
1 Introduction Prostate cancer (PCa), a prevalent urological malignancy, demonstrates substantial disease burden with elevated incidence and mortality. Epidemiological statistics from the American Cancer Society indicate PCa comprised 21% of all cancer diagnoses in 2020, corresponding to 191,930 new cases and 33,330 fatalities annually in the US [1].
Thromboxane receptor activation in dendritic cells mitigates sepsis by suppressing S100a8/a9-mediated neutrophil recruitment - Signal Transduction and Targeted Therapy Original
Abstract Dendritic cells (DCs) regulate both innate and adaptive immunity during sepsis. Prostaglandins (PGs), small lipid molecules derived from arachidonic acid via COX enzymes, are crucial regulators of immune homeostasis and inflammation. However, their role in sepsis pathogenesis remains poorly defined. In this study, we identified a significant negative correlation between DC depletion and disease severity in patients with sepsis.
LINA: Linear Autoregressive Image Generative Models with Continuous Tokens
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Correlation analysis and diagnostic performance of CT/MRI fat quantification parameters in metabolic dysfunction–associated steatotic liver disease
Abstract Introduction: Early quantitative diagnosis of metabolic dysfunction–associated steatotic liver disease (MASLD) is crucial for preventing disease progression. Fat analysis and calculation technique (FACT) MRI fat quantification has shown potential diagnostic value. This study aimed to compare the diagnostic performance of CT and MRI fat quantification techniques and to evaluate their correlation with clinical and biochemical markers in in patients with MASLD.
Outside Front Cover: Programmable Charge Transport in a Multichannel Single‐Molecule Parallel Circuit
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Programmable Charge Transport in a Multichannel Single‐Molecule Parallel Circuit
Conflict of Interests The authors declare no conflict of interest. Supporting Information Filename Description anie202513668-supp-0001-SuppMat.pdf10.3 MB Supporting Information References 1, , Chem. Phys. Lett. 1974, 29, 277–283. https://doi.org/10.1016/0009-2614(74)85031-1. 2, , , , , Chem. Rev. 2016, 116, 4318–4440. https://doi.org/10.1021/acs.chemrev.5b00680. 3, , , , , Nat. Rev. Mater. 2016, 1, 16002. https://doi.org/10.1038/natrevmats.2016.2. 4, , , Nat. Rev. Phys. 2019, 1, 381–396.
Frontiers | Depressive symptoms and Learning Motivation among Chinese freshmen: a longitudinal study using random intercept cross-lagged panel model and the subgroup analysis of parental educational background
Introduction Depressive symptoms have become increasingly prevalent in modern society. Characterized by low mood, reduced anhedonia, and decreased energy, depression is a severe mental health issue (1). The World Health Organization predicts that by 2030, depression may surpass cardiovascular and respiratory diseases to become a major cause of global disease burden (2).
Leaf Trait Divergence and Elevational Adaptation in Endangered Fagus hayatae: Conservation Insights for an East Asian Paleoendemic
1 Introduction Leaf functional traits—morphological and physiological adaptations to environmental conditions—serve as key indicators of plant ecological strategies along the Leaf Economics Spectrum (LES), a global axis ranging from acquisitive (fast resource capture) to conservative (stress-tolerant) strategies (Wright et al. 2004). Comparative analysis of functional traits between closely related and sympatric species holds significant ecological implications (Li et al. 2025).
Synergistic Antibacterial Strategy of AIEgens Photosensitizer CPTQ for Photodynamic Therapy and Ferroptosis-like Bacterial Death to Prevent Dental Caries
Abstract Click to copy section linkSection link copied! Dental caries, primarily caused by Streptococcus mutans (S. mutans) biofilms, remains a global health concern. Antimicrobial photodynamic therapy (aPDT) has shown promise in controlling cariogenic bacteria by generating reactive oxygen species (ROS), but the aggregation-caused quenching (ACQ) effect of traditional photosensitizers limits its efficacy.
Electric-field-promoted assembly of asymmetric junctions for single-molecule rectifiers
Electric-field-promoted assembly of asymmetric junctions for single-molecule rectifiers Electric-field-directed self-assembly enables unidirectional monolayer junction formation on gold substrate via terminal asymmetric Au–S and Au–C contacts, yielding stable rectifiers with defined polarity and diode I–V characteristics. This strategy defines a programmable method enabling the realization of uniform molecular-scale electronic devices through self-assembly.
Polymicrobial detection and salivary metabolomics of children with early childhood caries
Department of Pediatric Dentistry, Nanjing Stomatological Hospital, Affiliated Hospital of Medical School, Research Institute of Stomatology, Nanjing University, Nanjing, Jiangsu Province, China DOI 10.7717/peerj.19399 Academic Editor Rohit Upadhyay Subject Areas Microbiology, Dentistry, Epidemiology, Pediatrics Keywords Early childhood caries, Oral microbiology, Untargeted metabolomics Copyright © Licence This is an open access article distributed under the terms of the Creative Commons...
Targeting a key disulfide linkage to regulate RIG-I condensation and cytosolic RNA-sensing - Nature Cell Biology
Abstract Maintaining innate immune homeostasis is critical for preventing infections and autoimmune diseases but effective interventions are lacking. Here we identified C864–C869-mediated intermolecular disulfide-linkage formation as a critical step for human RIG-I activation that can be bidirectionally regulated to control innate immune homeostasis.
Comparison of Back Tuina and Oral Astragalus Methods to Enhance Immunosuppression in Rabbits and Prediction of Astragalus Targets for Immune Function Improvement
Conflicts of Interest The authors declare no conflicts of interest. References , , and . 2023. “Balancing Immunosuppression in Pediatric Liver Transplantation: Playing the Long Game.” Pediatric Transplantation 27, no. 8: e14575. https://doi.org/10.1111/petr.14575. , , , and . 2023. “Single-Cell Proteomics Enabled by Next-Generation Sequencing or Mass Spectrometry.” Nature Methods 20, no. 3: 363–374. https://doi.org/10.1038/s41592-023-01791-5. , , , , , and . 2023.
Mobile Application and Machine Learning-Driven Scheme for Intelligent Diabetes Progression Analysis and Management Using Multiple Risk Factors
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Global Prevalence of Perinatal Depression and Its Determinants Among Rural Women: A Systematic Review and Meta‐Analysis
1. Introduction Perinatal depression (PND) refers to the occurrence of a depressive episode in a woman during pregnancy and within the first year after giving birth [1]. It is one of the most common medical complications during pregnancy and postpartum, which includes major and minor depressive episodes [2]. The global burden of PND is 11.9%, with a higher prevalence in low- and middle-income countries (13.1%) than in high-income countries (11.4%) [3].
Acetylation of PGK1 at lysine 323 promotes glycolysis, cell proliferation, and metastasis in luminal A breast cancer cells - BMC Cancer
Gene Ontology (GO) annotations for acetylated proteins were obtained from the UniProt-GOA database. Initially, identified protein IDs were converted to UniProt IDs and subsequently mapped to GO IDs. For proteins not annotated in the UniProt-GOA database, InterProScan software was employed to assign GO functions based on a protein sequence alignment method. The proteins were then categorized into two GO categories: biological process and molecular function.
Microfluidic-Enabled Assembly of Multicomponent Artificial Organelle for Synergistic Tumor Starvation Therapy
Biological and Medical Applications of Materials and InterfacesJuly 28, 2024 Ting Pan National Advanced Medical Engineering Research Center, China State Institute of Pharmaceutical Industry, Shanghai 201203, P. R. China State Key Laboratory of Natural Medicines, Department of Pharmaceutics, School of Pharmacy, China Pharmaceutical University, Nanjing 210009, P. R.
Solvents regulated packing porosity of a bilayer metal-organic cage
Solvents regulated packing porosity of a bilayer metal-organic cage Metal-organic cages (MOCs) are an emerging class of porous materials with promising applications. However, controlling the configuration of the cage packing, which can influence the overall porosity of the materials, remains a difficulty, as many factors can influence the cage assembly and stacking.
Facile Prepared MOF-OH-PAN Nanofiber for Separation Co(II) from Waste Batteries
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Lipid nanoparticles as the drug carrier for targeted therapy of hepatic disorders
Lipid nanoparticles as the drug carrier for targeted therapy of hepatic disorders The liver, a complex and vital organ in the human body, is susceptible to various diseases that have emerged as significant contributors to global morbidity and mortality over recent decades. These diseases include metabolic disorders, acute hepatitis, cirrhosis, and hepatocellular carcinoma. Currently, liver transplantation remains the most effective treatment for hepatic disorders.
Treatment of vitiligo and alopecia areata in a child
Back to Journals » Clinical, Cosmetic and Investigational Dermatology » Volume 17 Authors Mu Y, Pan T, Chen L Received 22 April 2024 Accepted for publication 29 July 2024 Published 6 August 2024 Volume 2024:17 Pages 1789—1792 DOI https://doi.org/10.2147/CCID.S467026 Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 4 Editor who approved publication: Dr Monica K.
Hydrogen Production via Electrolysis of Wastewater
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Membrane-Anchored Aggregation-Induced Emission Luminogens: Accurate Labeling and Efficient Photodynamic Inactivation of Streptococcus mutans in Anticaries Therapy
RETURN TO ARTICLES ASAPPREVBiological and Medic...Biological and Medical Applications of Materials and InterfacesNEXT Ting Pan Hospital of Stomatology, Guanghua School of Stomatology, Sun Yat-Sen University, Guangzhou 510055, China Guangdong Provincial Key Laboratory of Stomatology, Guangzhou 510055, China Guangdong Key Laboratory for Dental Disease Prevention and Control, Guangzhou 510055, China , Yixue Li Hospital of Stomatology, Guanghua School of Stomatology, Sun Yat-Sen University,...
Social Inhibition and Depressive Symptoms among Couples with Children with Autism Spectrum Disorder: The Mediating Role of Perceived Family Support
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Opto‐Hydrodynamic Driven 3D Dynamic Microswarm Petals (Laser Photonics Rev. 18(3)/2024)
Graphical Abstract Opto-Hydrodynamic-Driven 3D Dynamic Microswarms In article number 2300480, Xing Li, Yang Shi, Hongbao Xin, and co-workers present a convenient opto-hydrodynamic strategy for 3D dynamic microswarm petals actuation based on the photothermal gradient-induced Marangoni effect. Such microswarm petals are controllably reconfigurable, deformable, and capable of performing stable migration.
Social Inhibition and Depressive symptoms among Couples Having Children with Autism Spectrum Disorder: The Mediating Role of Perceived Family Support
Preprint Article Version 1 This version is not peer-reviewed Version 1 : Received: 23 February 2024 / Approved: 26 February 2024 / Online: 26 February 2024 (10:26:06 CET) Pan, T.; Wongpakaran, T.; Wongpakaran, N.; He, B.; Wedding, D. Social Inhibition and Depressive symptoms among Couples Having Children with Autism Spectrum Disorder: The Mediating Role of Perceived Family Support. Preprints 2024, 2024021424.
Manipulation of Surface Electrical Charge on Nanocomposite Membranes Confers Wide Spectrum Bactericidal Effects and Promotes Tissue Regeneration
Conflict of Interest The authors declare no conflicts of interest. Supporting Information Filename Description adfm202314024-sup-0001-SuppMat.pdf646.2 KB Supporting Information References 1, , , Science 2017, 356, 1026. 2, , , Sci. Transl. Med. 2014, 6, 265sr6. 3, , , , Periodontol. 2000, 79, 107. 4, , Microbiol. Mol. Biol. Rev. 2010, 74, 417. 5, , , , EMBO Rep. 2020, 21, e51034. 6, , , , , , J. Control. Release. 2022, 341, 147. 7, , , , , ACS Nano 2022, 16, 19840. 8, , , , , , , , , J. Hazard. Mater.
Physicochemical properties of functionalized A200 and SBA-15 nanoparticles with enhanced amphiphilicity for Pickering emulsions
Physicochemical properties of functionalized A200 and SBA-15 nanoparticles with enhanced amphiphilicity for Pickering emulsions† Pickering emulsions are considered as promising chemical oil repellents in enhanced oil recovery (EOR). In this paper, an amphiphilic block copolymer poly(ethylene glycol)–poly(dopamine methacrylamide) (mPEG–PDMA, abbreviated as mp) containing catechol adhesion groups was synthesized.
Keratin 15 protects against cigarette smoke-induced epithelial mesenchymal transformation by MMP-9 - Respiratory Research
References Safiri S, Carson-Chahhoud K, Noori M, et al. Burden of chronic obstructive pulmonary disease and its attributable risk factors in 204 countries and territories, 1990–2019: results from the Global Burden of Disease Study 2019. BMJ. 2022;378: e069679. PubMed PubMed Central Google Scholar Lareau SC, Fahy B, Meek P, Wang A. Chronic obstructive pulmonary disease (COPD). Am J Respir Crit Care Med. 2019;199:1–2. Google Scholar Burgel PR, Bourdin A, Chanez P, et al.
SARS-CoV-2 Nsp8 suppresses MDA5 antiviral immune responses by impairing TRIM4-mediated K63-linked polyubiquitination
Loading metrics Open Access Peer-reviewed Research Article ? This is an uncorrected proof. Citation: Zhang X, Yang Z, Pan T, Sun Q, Chen Q, Wang P-H, et al. (2023) SARS-CoV-2 Nsp8 suppresses MDA5 antiviral immune responses by impairing TRIM4-mediated K63-linked polyubiquitination. PLoS Pathog 19(11): e1011792.
Fuzzy Comprehensive Evaluation of Pilot Cadets’ Flight Performance Based on G1 Method
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Opto‐Hydrodynamic Driven 3D Dynamic Microswarm Petals
Conflict of Interest The authors declare no conflict of interest. Supporting Information Filename Description lpor202300480-sup-0001-SuppMat.pdf787 KB Supporting Information lpor202300480-sup-0002-VideoS1.mp49.2 MB Supporting Information lpor202300480-sup-0003-VideoS2.mp49.5 MB Supporting Information lpor202300480-sup-0004-VideoS3.mp410.2 MB Supporting Information References 1, Science 1963, 141, 357. 2, , , , , Nature 2021, 594, 345. 3, , , , Sci. Rob. 2021, 6, 2470. 4, , , , Nature 2010, 464, 890.
Wake‐Riding Effect‐Inspired Opto‐Hydrodynamic Diatombot for Non‐Invasive Trapping and Removal of Nano‐Biothreats (Adv. Sci. 18/2023)
Graphical Abstract Opto-Hydrodynamic Diatombot In article number 2301365, Baojun Li, Hongbao Xin, and co-workers report a wake-riding effect-inspired opto-hydrodynamic diatombot for non-invasive trapping and removal of nano-biothreats with sizes down to sub-100 nm such as adenoviruses, pathogenic bacteria, and mycoplasmas. This diatombot can be directly used in cell cultures, without affecting culturing cells including precious cells such as hippocampal neurons.
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