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Articles by Ting Sun
Targeting receptor tyrosine kinases: from molecular mechanisms to clinical therapeutics
Abstract Receptor tyrosine kinases (RTKs), constituting a major family of cell-surface transmembrane receptors, are essential for intracellular tyrosine phosphorylation and signal transduction. RTK signaling is crucial for cellular fate regulation and tissue homeostasis, and its disruption is linked to numerous diseases.
Gut microbiome features in methamphetamine use disorder: external validation of a candidate marker panel and exploratory multi-omics associations
Abstract Methamphetamine use disorder (MUD) is a chronic, relapsing disorder with symptoms most pronounced during withdrawal, yet objective biomarkers remain lacking. Although gut microbial alterations have been reported in substance use disorders, their potential as candidate markers, longitudinal patterns, and symptom associations in MUD remain unclear. Gut microbiota profiles were analysed in 103 participants with MUD and 80 healthy controls.
Uric acid-to-HDL-cholesterol ratio and incident carotid atherosclerosis: a retrospective cohort study
Abstract Background: The uric acid-to-HDL-cholesterol ratio (UHR) has been proposed as a composite cardiometabolic biomarker, but prospective evidence linking UHR to incident carotid atherosclerosis remains limited. Methods: In a retrospective cohort of 16,572 adults from a tertiary health examination center in Zhejiang, China, we examined the association between baseline UHR and incident carotid artery lesions using Cox proportional hazards regression.
The organelle oxidative-inflammatory network in polycystic ovary syndrome: from subcellular intercellular cascades to systemic comorbidities
Abstract Polycystic ovary syndrome (PCOS) transcends localized reproductive dysfunction, manifesting as a systemic metabolic disorder driven primarily by insulin resistance (IR) and chronic inflammation. The condition was recently redesignated as polyendocrinometabolic syndrome (PMOS) to better reflect this systemic pathophysiology.
Factor IX Padua AAV gene therapy in adolescents with hemophilia B: a phase 1 trial
Abstract Adeno-associated virus (AAV)-mediated factor IX Padua gene therapy has demonstrated good safety and efficacy in adult patients with hemophilia B, but its safety and efficacy in adolescent patients with hemophilia B remain unknown. Here we report a multicenter, single-arm, phase 1 study involving 11 adolescent participants (aged 12–18 years) with severe or moderately severe hemophilia B (factor IX coagulant activity (FIX:C) ≤2 IU dl−1) in China.
Artery tertiary lymphoid organs encode a pathogenic high-affinity autoantibody−autoantigen pair in atherosclerosis
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Abstract Artery tertiary lymphoid organs (ATLOs) emerge in atherosclerosis, which is a chronic inflammatory artery disease with an autoimmune component. However, whether disease-relevant autoimmune B cells emerge in ATLOs remains unknown. In this study, we isolate germinal center (GC) B cells from ATLOs and lymph nodes from healthy and atherosclerosis-burdened mice, expression clone 60 autoantibodies and screen them for arterial wall reactivity.
By Chuankai Zhang, Xi Zhang, Yi Ran, Zhihua Wang, Liping Li, Shu Wang, Junjie Zheng, Yixin Zhang, Ting Sun, Yutao Li, Shu Ying Lu, Mingyang Hong, Zhe Ma, Sabine Steffens, Michael Hristov, Xavier Blanchet, Xinwen Dou, Xinyi Deng, Klaus Dornmair, Desheng Hu, Shibojyoti Lahiri, Axel Imhof, Nadja Sachs, Lars Maegdefessel, Jingyi Xiao, Jianning Zhang, Yan Wang, Hua Hong, Livia Habenicht, Xinyu Weng, Junbo Ge, Christian Weber, Donato Santovito, Rachael Bashford-Rogers, Sarajo Mohanta, Klaus Ley, Andreas Habenicht, Changjun Yin, Jingpu Zhu
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Nature
Verified
Unlocking Low-Melting-Point and High-Conductivity Molten Salts via High-Entropy Strategy with Demonstration in Thermal Batteries
1 Introduction The development of high-performance high-temperature electrochemical devices is fundamentally governed by the availability of advanced electrolyte materials [1-6]. Among them, molten salts serve as the cornerstone for a wide range of applications in thermal batteries, liquid metal batteries, and high-temperature fuel cells due to their high ionic conductivity, wide electrochemical window, and excellent thermal stability [7-12].
Development and temporal validation of a postoperative nomogram based on clinical, surgical, histopathological, and semi-quantitative EEG features for predicting seizure-free survival in children after focal epilepsy surgery
Abstract Objective: Accurate estimation of seizure recurrence risk after pediatric epilepsy surgery may support individualized postoperative surveillance and management. This study aimed to develop and temporally validate a prognostic nomogram for estimating 1-year and 2-year seizure-free survival after focal or lobar resection in children with drug-resistant epilepsy. Methods: This single-center retrospective cohort study included 256 children treated between 2015 and 2024.
The association between tooth loss and cognitive function in middle-aged and elderly people in China: A multiple mediation analysis based on the biopsychosocial model
Research ArticleArticles in PressOpen access Affiliations & Notes 1School of Nursing, Guizhou Medical University, Guiyang, China 2Guizhou Medical University Department of Pathophysiology, Guizhou Medical University, Guiyang, China 3The Department of Neurology, Affiliated Hospital of Guizhou Medical University, Guiyang, China Article Info Publication History: Received September 10, 2025; Revised August 2, 2026; Accepted August 10, 2026; Published online August 12, 2026 DOI:...
Phylogenomic discordance and ancestral variation in rapidly radiating felids
Keywords phylogenomic discordance incomplete lineage sorting introgression Pallas’s cat Get full text access Log in, subscribe or purchase for full access. References 1. Maddison, W.P. Gene Trees in Species Trees Syst. Biol. 1997; 46:523-536 2. Avise, J.C. ∙ Robinson, T.J. Hemiplasy: a new term in the lexicon of phylogenetics Syst. Biol. 2008; 57:503-507 3. Szöllősi, G.J. ∙ Davín, A.A. ∙ Tannier, E. ... Genome-scale phylogenetic analysis finds extensive gene transfer among fungi Philos. Trans. R. Soc.
Global–Local Skeleton Constraint-Based BIM-GIS Integration Modeling Method for Railway Infrastructure
N., T.Sun, Y.Hu, et al. 2026. “Global–Local Skeleton Constraint-Based BIM-GIS Integration Modeling Method for Railway Infrastructure.” Transactions in GIS30, no. 4: e70300. Zhan, https://doi.org/10.1111/tgis.70300. Conflicts of Interest The authors declare no conflicts of interest. Data Availability Statement The data that support the findings of this study are available from the corresponding author upon reasonable request. References , , and . 2023.
Measuring health professional students' willingness to use AI chatbots in learning: A fuzzy-set qualitative comparative analysis
CONFLICT OF INTEREST STATEMENT We have no known conflict of interest to disclose. DATA AVAILABILITY STATEMENT All relevant raw data from this paper were made freely available to researchers for non-commercial use. The datasets generated and/or analyzed during the study could be requested from the corresponding author upon request. REFERENCES 1, , . Efficient healthcare with large language models: optimizing clinical workflow and enhancing patient care. J Am Med Inform Assoc. 2024; 31(6): 1436–1440.
Computer Science > Machine Learning
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Noninvasive molecular subtyping of breast cancer using multimodal ultrasound spatiotemporal transformer
Abstract Molecular subtyping is essential for guiding systemic therapy in breast cancer but currently requires invasive biopsy. Conventional B-mode ultrasound offers rich anatomical information, yet lacks the functional dynamics needed to capture the comprehensive biology of tumors.
Low-dose oral nicotinamide mononucleotide for immune thrombocytopenia: a phase 1/2 trial
Abstract Autoimmunity remains challenging to treat without broad immunosuppression. We previously showed that anti-CD38 antibody can rapidly elevate platelet counts in refractory immune thrombocytopenia (ITP), but the underlying mechanism was unclear. Here we report that anti-CD38 antibody induces platelet recovery within 3 days, including after retreatment in relapsed cases.
Preoperative albumin to carcinoembryonic antigen ratio predicts clinicopathological features and survival in colorectal cancer: a prognostic nomogram study
Abstract Aim: This study examined the association between the preoperative albumin-to-carcinoembryonic antigen ratio (ACR) and clinicopathological characteristics in colorectal cancer (CRC) patients and developed and validated a prognostic model incorporating ACR for patient risk stratification.
Doxorubicin promotes the production of inflammatory cytokines in tumor-associated macrophages through activating lactate dehydrogenase A
Abstract Glioblastoma (GBM) presents a significant challenge because of its immunosuppressive microenvironment. The standard treatment protocol, including surgery, radiotherapy, and temozolomide, has been unable to alleviate immunosuppression. Doxorubicin chemotherapy induces immunogenic cell death in cancer cells, reshaping an immune-activated microenvironment. Here, we investigated the mechanism of immune activation induced by doxorubicin in tumor-associated macrophages (TAMs).
PAK4 functions as an immune suppressor by reprogramming the phosphatidylcholine metabolism of CD8 + T cells within the glioblastoma tumor microenvironment
Abstract Glioblastoma multiforme (GBM) is a highly aggressive primary brain tumor that represents a significant therapeutic challenge because of its immunosuppressive tumor microenvironment (TME). GBM employs multiple sophisticated mechanisms for immune evasion, including proinflammatory cytokine secretion and immune cell effector function impairment. Due to these complex immune evasion strategies, immunotherapies are effective in only a minority of GBM patients.
Distinct radial glia subtypes regulate midbrain dopaminergic neuron development - Nature Neuroscience
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Abstract Understanding the development of midbrain dopaminergic (mesDA) neurons is essential for advancing cell replacement therapies for Parkinson’s disease. In the developing ventral midbrain (VM), radial glia (Rgl) cells are the progenitors of mesDA neurons. However, distinct Rgl subtypes have recently been identified, and their individual roles are unclear. Here we analyze transcriptomic data from mouse and human VM Rgl to define their contributions to mesDA neuron development.
By Emilía Sif Ásgrímsdóttir, Luca Fusar Bassini, Ting Sun, Clàudia Puigsasllosas Pastor, Daniel Gyllborg, Christopher Grigsby, Saiful Islam, Peter Lönnerberg, Carmen Salto, Roger Barker, Sten Linnarsson, Gonçalo Castelo-Branco, Gioele La Manno, Enrique M. Toledo, Ernest Arenas, Kawai Lee, Baptiste Jude, Carmen Abaurre, Carlos Villaescusa
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Nature
Verified
A CLE11b‐CLE16 Signaling Relay Mediates Root‐Shoot‐Root Crosstalk for Drought Adaptation in Common Bean
1 Introduction Soil drought, a prevalent environmental stressor, poses a significant constraint on global crop production [1-3]. In response to drought stress, plants undergo a range of phenotypic adjustments to optimize water use and survival. In the aerial parts, particularly the leaves, common adaptations include stomatal closure, reduced leaf expansion, and leaf rolling, which are strategies limiting water loss through transpiration [4-6].
Association Between Body Composition and Risk of Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis
Introduction Overweight and obesity are characterized by excessive body fat accumulation.1 The number of people with overweight and obesity globally has increased rapidly in recent years, and it is projected to exceed 50% by 2025.2 The rising trend has been paralleled by a proportional increase in the incidence of type 2 diabetes mellitus (T2DM).3 In 2024, the 11th edition of the IDF Diabetes Atlas reported that about 589 million adults worldwide were living with T2DM.
Bone Health in Adults With Severe Haemophilia Receiving Different Prophylactic Treatments
1 Introduction Haemophilia is an X-linked congenital bleeding disorder caused by deficiency of factor VIII (FVIII) or factor IX (FIX). Patients with haemophilia (PWH), particularly severe cases, develop recurrent joint and muscle bleeds since childhood, resulting in arthropathy and morbidity [1]. Prophylactic factor replacement is the standard treatment [1, 2], effectively reducing bleeding and preventing permanent damage.
Anoctamin-2-specific T cells link Epstein-Barr virus to multiple sclerosis
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Keywords multiple sclerosis Epstein-Barr virus autoimmunity T cells molecular mimicry anoctamin-2 Introduction Multiple sclerosis (MS) causes neurological disability in young adults, with an estimated 2.8 million patients worldwide.1 MS is characterized by inflammatory lesions in the central nervous system (CNS) and usually presents clinically with a relapsing-remitting phenotype.2 Both environmental and stochastic events contribute to MS in genetically susceptible individuals,3 with the...
By Olivia Thomas, Urszula Rykaczewska, Marina Galešić, Nils Hallen, Filippo Ferro, Mattias Bronge, Zoe Marti, YUE LI, Alexandra Hill Riqué, Jianing Lin, Aleksa Krstić, Alicja Gromadzka, András Levente Szonder, Chiara Sorini, Ting Sun, Ozge Dumral, Rasmus Berglund, Majid Pahlevan Kakhki, Milena Z. Adzemovic, Manuel Zeitelhofer, Katarina Tengvall, Ola Nilsson, Erik Holmgren, Chiara Starvaggi Cucuzza, Klara Asplund Högelin, Guro Gafvelin, Katharina Fink, Gonçalo Castelo-Branco, Maria Needhamsen, Mohsen Khademi, Fredrik Piehl, Torbjörn Gräslund, Lars Alfredsson, Harald Lund, Per Uhlén, Ingrid Kockum, Roland Martin Verified, Maja Jagodic, Hans Grönlund, Andre Ortlieb Guerreiro-Cacais, Tomas Olsson, María Reina-Campos, Birce Akpinar
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Cell Press
Verified
Anoctamin-2-specific T cells link Epstein-Barr virus to multiple sclerosis
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Keywords multiple sclerosis Epstein-Barr virus autoimmunity T cells molecular mimicry anoctamin-2 Introduction Multiple sclerosis (MS) causes neurological disability in young adults, with an estimated 2.8 million patients worldwide.1 MS is characterized by inflammatory lesions in the central nervous system (CNS) and usually presents clinically with a relapsing-remitting phenotype.2 Both environmental and stochastic events contribute to MS in genetically susceptible individuals,3 with the...
By Olivia Thomas, Urszula Rykaczewska, Marina Galešić, Nils Hallen, Filippo Ferro, Mattias Bronge, Zoe Marti, YUE LI, Alexandra Hill Riqué, Jianing Lin, Aleksa Krstić, Alicja Gromadzka, András Levente Szonder, Chiara Sorini, María Reina-Campos, Ting Sun, Ozge Dumral, Rasmus Berglund, Majid Pahlevan Kakhki, Milena Z. Adzemovic, Manuel Zeitelhofer, Birce Akpinar, Katarina Tengvall, Ola Nilsson, Erik Holmgren, Chiara Starvaggi Cucuzza, Klara Asplund Högelin, Guro Gafvelin, Katharina Fink, Gonçalo Castelo-Branco, Maria Needhamsen, Mohsen Khademi, Fredrik Piehl, Torbjörn Gräslund, Lars Alfredsson, Harald Lund, Per Uhlén, Ingrid Kockum, Roland Martin Verified, Maja Jagodic, Hans Grönlund, Andre Ortlieb Guerreiro-Cacais, Tomas Olsson
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Cell Press
Verified
Rapid population expansion drives the widespread spread of a dominant anticoagulant‐resistance Vkorc1 allele in Asian house rats (Rattus tanezumi) across China
CONFLICT OF INTEREST The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. DATA AVAILABILITY STATEMENT The data that support the findings of this study are openly available in NCBI at https://www.ncbi.nlm.nih.gov/, reference number PV878506~PV878563. Supporting Information Filename Description ps70480-sup-0001-FigureS1-S4.docxWord 2007 document , 6.5 MB Fig. S1.
Author Correction: Neuroimmune cardiovascular interfaces control atherosclerosis
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Icon version of the Flipboard logo nature.com - Sarajo K. Mohanta , Li Peng, Yuanfang Li, Shu Lu, Ting Sun, Lorenzo Carnevale, Marialuisa Perrotta, Zhe Ma, Benjamin Förstera, Karen Stanic, Chuankai Zhang, Xi Zhang, Piotr Szczepaniak, Mariaelvy Bianchini, Borhan R. Saeed, Raimondo Carnevale, Desheng Hu, Ryszard Nosalski, Fabio Pallante, Michael Beer, Donato Santovito, Ali Ertürk, Thomas C. Mettenleiter, Barbara G. Klupp, Remco T. A.
By Sarajo Mohanta, Li Peng, Yuanfang Li, Shu Fa Lu, Ting Sun, Lorenzo Carnevale, Marialuisa Perrotta, Zhe Ma, Karen Stanic, Chuankai Zhang, Xi Zhang, Piotr Szczepaniak, Mariaelvy Bianchini, Borhan R. Saeed, Raimondo Carnevale, Desheng Hu, Ryszard Nosalski, Fabio Pallante, Michael Beer, Donato Santovito, Ali Erturk, Thomas C. Mettenleiter, Barbara Klupp, Sabine Steffens, Jaroslav Pelisek, Hans-Henning Eckstein, Robert Kleemann, Ziad Mallat, Jean-Baptiste Adolphe Michel, Jürgen Bernhagen, Martin Dichgans, Giuseppe D’Agostino, Tomasz J. Guzik, Peder S. Olofsson, Changjun Yin, Giuseppe Lembo, Daniela Carnevale, Benjamin Förstera, Livia Habenicht, Christian Weber
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Flipboard
Sabotaged Integral HSC Heterogeneity Underlies Essential Thrombocythemia Development
1 Introduction Philadelphia-negative myeloproliferative neoplasms (Ph− MPNs) are clonal disorders driven by malignant hematopoietic stem cells (HSCs),[1, 2] comprising polycythemia vera (PV), essential thrombocythemia (ET), and primary myelofibrosis (PMF).[3] Among them, ET is associated with increased megakaryocyte (Mk) and platelet production in the bone marrow (BM), with most cases associated with the janus kinase 2 gene (JAK2),[3-5] calreticulin (CALR),[6, 7] or thrombopoietin receptor...
A novel nutritional immune risk score model for long-term prognosis in colorectal cancer using clustering and principal component analysis
Abstract Background: Survival outcomes among patients with colorectal cancer (CRC) often differ despite identical disease stages, partly due to variations in nutritional and immune status. Malnutrition can impair immune defense, exacerbate inflammatory responses, and influence tumor progression, ultimately contributing to a poorer prognosis.
Glycyrrhizic Acid Ameliorates LPS‐Induced WI‐38 Cell Inflammation, Oxidative Stress, and Ferroptosis via Targeting METTL14 in Infantile Pneumonia
Disclosure Animal studies were performed in compliance with the ARRIVE guidelines and the Basel Declaration. All animals received humane care according to the National Institutes of Health (USA) guidelines. Conflicts of Interest The authors declare no conflicts of interest. References 1, , and , “Integrative Physiology of Pneumonia,” Physiological Reviews 98, no. 3 (2018): 1417–1464.
Improving Polarization Hysteresis to Enhance Dielectric and Energy Storage Performance of Polyvinylidene Difluoride‐Based Nanocomposite Films
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Multiparametric Correlative Topographical and Volumetric Fluorescence Microscopy
Abstract Live-cell imaging of cell surface topography and intracellular architecture is essential for understanding cellular function. However, conventional approaches often involve trade-offs between resolution, invasiveness, and volumetric coverage.
FKBP5 Mediates Alveolar Fibroblast Necroptosis During Acute Respiratory Distress Syndrome
1 Introduction Acute respiratory distress syndrome (ARDS) is a prevalent and severe condition that poses a significant threat to human health. Epidemiological studies indicate that ARDS patients constitute approximately 10% of all individuals hospitalised in intensive care units, with a mortality rate ranging from 30% to 50% [1]. ARDS represents a critical public health challenge that necessitates immediate attention and intervention [2].
A Novel Class of Multi‐substituted Diaryl Scaffold Derivatives Inhibit Glioblastoma Progression by Targeting CD155
1 Introduction Glioblastoma (GBM) is recognized as the most aggressive form of glioma, accounting for a concerning 48.6% of all malignant primary central nervous system cancers.
Exploring the nematic transition temperatures of pyridine-containing liquid crystalline compounds by explainable machine learning model
ABSTRACT By the combination application of machine learning methods and SHapley Additive exPlanations (SHAP) analysis, explainable machine learning models were built for the first time to explore the nematic–isotropic transition behaviour of pyridine-containing liquid crystalline compounds. All models were fully validated. The results show that these models have high goodness of fit, robustness and prediction ability.
Family Members’ Perspectives on Integrative Chinese-Western Medicine in Cancer Care
Abstract Purpose Family members play a central supporting role in cancer patient management. This study aimed to assess the knowledge, attitudes, and practices (KAP) of cancer patients’ family members regarding the use of integrative Chinese-Western medicine in cancer treatment. Proper knowledge is necessary for informed decision-making and providing adequate care and support.
The deubiquitinase YOD1 suppresses tumor progression by stabilizing ZNF24 in clear cell renal carcinoma - Cell Death & Disease
Abstract Metastasis remains a significant challenge in the management of clear cell renal cell carcinoma (ccRCC), and a continued focus on its underlying mechanisms is crucial for improving patient outcomes and optimizing clinical therapies. The ovarian-tumor related protease (OTU) is involved in regulating critical cell signaling pathways, but the functions of most OTUs have yet to be explored.
Visible‐Light Induced Cyclization to Carbazole‐Fused Eight‐Membered Diazocan‐5‐ones
Supporting Information As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors. Filename Description adsc202500322-s1-SI_1.docx4 MB Supplementary adsc202500322-s2-SI_2.pdf3.1 MB Supplementary
Ginkgo biloba leaf extract alleviates paraquat-induced RLE-6TN cell damage via the miR-155-5p/SIRT1/TLR4 axis
Abstract Ginkgo biloba extract (GBE) has demonstrated therapeutic potential in paraquat (PQ)-induced injury; however, its molecular mechanism remains unclear. The cell viability, lactate dehydrogenase (LDH) release, and apoptosis of RLE-6TN cells were assessed using CCK-8, LDH assay, and flow cytometry. Oxidative stress was evaluated using the DCFH-DA probe, while inflammatory cytokine levels (TNF-α, IL-1β, and IL-6) were measured via ELISA. The expression of miR-155-5p was analyzed using qRT-PCR.
ARAP1‐AS1 Overexpression Increases Diffuse Large B Cell Lymphoma Progression by Sponging miR‐508-5p to Activate the EMP1‐PI3K/AKT Pathway
Conflicts of Interest The authors declare no conflicts of interest. Supporting Information Filename Description hon70056-sup-0001-suppl-data.docx25.3 KB Supporting Information S1 hon70056-sup-0002-suppl-data.docx1.6 MB Supporting Information S2 References 1, “Hodgkin Lymphoma: 2023 Update on Diagnosis, Risk-Stratification, and Management,” American Journal of Hematology 97, no. 11 (2022): 1478–1488, https://doi.org/10.1002/ajh.26717.
Closely Spaced Multi-Target Association and Localization Using BR and AOA Measurements in Distributed MIMO Radar Systems
1. Introduction Recently, multiple-input multiple-output (MIMO) radar systems have drawn significant attention. Based on the antenna configurations, MIMO radar systems can be categorized into distributed and collocated ones. The former employs widely distributed antennas to exploit spatial diversity of the target, leading to enhanced performance in target detection and parameter estimation [1,2,3,4,5,6,7].
Clinical traits of adult depression with ADHD comorbidity
Liping Dong,1,2 Ting Sun,2 Ping Tong,2 Xiaoyan Ke1 1Affifiliated Nanjing Brain Hospital, Nanjing Medical University, Nanjing, 210029, People’s Republic of China; 2Department of Clinical Psychology, Northern Jiangsu People’s Hospital, Yangzhou, 225001, People’s Republic of China Correspondence: Ping Tong, Department of Clinical Psychology, Northern Jiangsu People’s Hospital, No. 98, Nantong West Road, Yangzhou, 225001, People’s Republic of China, Email [email protected] Xiaoyan Ke, Affiliated...
Effect of Ti and TiNb Microalloying on Microstructures and Mechanical Properties of 2200 MPa Low-Alloy Ultra-High-Strength Steels
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Interactions Between Bacterivorous Nematodes and Bacteria Reduce N2O Emissions
1 Introduction Nitrous oxide (N2O) is a potent long-lived greenhouse gas, with a global warming potential 300 times that of carbon dioxide, contributing to climate change and also ozone depletion.[1] Reducing N2O emissions is essential to mitigate climate change impacts.
PlantRing: A high-throughput wearable sensor system for decoding plant growth, water relations and innovating irrigation
Abstract The combination of flexible electronics and plant science has generated various plant-wearable sensors, yet challenges persist in their applications in real-world agriculture, particularly in high-throughput settings. Overcoming the trade-off between sensing sensitivity and range, adapting them to a wide range of crop types, and bridging the gap between sensor measurements and biological understandings remain the primary obstacles.
Liquid biopsy in cancer current: status, challenges and future prospects - Signal Transduction and Targeted Therapy
Abstract Cancer has a high mortality rate across the globe, and tissue biopsy remains the gold standard for tumor diagnosis due to its high level of laboratory standardization, good consistency of results, relatively stable samples, and high accuracy of results. However, there are still many limitations and drawbacks in the application of tissue biopsy in tumor. The emergence of liquid biopsy provides new ideas for early diagnosis and prognosis of tumor.
Knowledge, attitudes, and practices of family members of cancer patien
Ting Sun,1,2,* Ting Wang,2,* Fan Xia,3 Lin Xia,4 Xin Sun,2 Haili Jiang,2 Panlin Xu,2 Ping Li1 1Graduate School, Anhui University of Chinese Medicine, Hefei, Anhui, 230012, People’s Republic of China; 2Oncology Department of Integrated Traditional Chinese and Western Medicine, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, 230000, People’s Republic of China; 3Hefei Cancer Hospital, Chinese Academy of Sciences, Hefei, 230031, People’s Republic of China;...
The Mediating Effect of Emotional Regulation Between Psychological Res
Xiaoyan Xie,1 Ting Sun,2 Yumei Wu,1 Liping Dong2 1Department of Hematology, Northern Jiangsu People’s Hospital, Yangzhou, 225001, People’s Republic of China; 2Department of Clinical Psychology, Northern Jiangsu People’s Hospital, Yangzhou, 225001, People’s Republic of China Correspondence: Yumei Wu, Department of hematology, Northern Jiangsu People’s Hospital, No. 98, Nantong West Road, Yangzhou, 225001, People’s Republic of China, Email [email protected] Liping Dong, Department of Clinical...
Distributed Improved RILOS Guidance-Based Formation Control of Underactuated ASVs for Cooperative Maritime Search
1. Introduction From 2014 to 2022, the European Maritime Safety Agency (EMSA) reported that there was a total of 21,173 maritime accidents, resulting in 6781 injuries and 604 lives lost [1]. Maritime accidents can result in catastrophic damages; thus, the maritime search and rescue (MSAR) operation is significant.
Nanosecond laser cleaning method for high-capacity fast storage and data multiplexing in ARM architecture
As the application of laser cleaning technology continues to expand, various fields have put forward higher requirements for the performance and quality of the operation, and at present, laser cleaning has problems such as low efficiency in handling repetitive tasks, and the system deployment and maintenance costs are high.
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