Vanessa Smith
Charlottesville
As seen in:
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Foodie, former chef, coffee addict and obsessed furbaby mom.
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Articles by Vanessa Smith
City's bureaucratic error interrupts life-saving care for HIV patients
Chicago is in the middle of a quietly unfolding public health crisis. New HIV diagnoses are rising: 818 Chicagoans were newly diagnosed in 2024, according to the Chicago Department of Public Health. That’s a 12.5% increase over 2023 and nearly 30% higher than 2022. The communities bearing the greatest burden are Black and Hispanic Chicagoans on the city’s South and West sides, where structural inequities have long shaped health outcomes.
Patient-specific alterations in blood plasma cfRNA profiles enable accurate classification of cancer patients and controls - Communications Medicine
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Abstract Circulating nucleic acids in blood plasma form an attractive, minimally invasive resource to study human health and disease. In this study, we aimed to identify cell-free RNA alterations that can distinguish cancer patients from cancer-free individuals. We first performed mRNA capture sequencing on 266 blood plasma samples from cancer patients and controls, including a discovery set of 208 donors across 25 cancer types and a replication set of 58 donors across three cancer types.
By Annelien Morlion, Philippe Decruyenaere, Jasper Anckaert, Justine Nuytens, Eveline Vanden Eynde, Kimberly Verniers, Celine Everaert, Guy G. Brusselle, Steven Callens, Filomeen Haerynck, Dimitri Hemelsoet, Eric Hoste Verified, Jo Lambert, Nicolaas Lumen, Fritz Offner, Koen Paemeleire, Vanessa Smith, Jo Van Dorpe, Amber Vanhaecke, Hans Van Vlierberghe, An Mariman, Olivier Thas, Jo Vandesompele, Pieter Mestdagh, Kathleen Schoofs, Nickolas Johns Ramirez, Lies Van den Eynde
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Nature
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Dynamic macrophage phenotypes in autoimmune and inflammatory rheumatic diseases - Nature Reviews Rheumatology
Abstract Macrophages regulate inflammatory and fibrotic processes in several autoimmune and inflammatory rheumatic diseases. They are highly plastic cells, shifting within a range of pro-inflammatory and anti-inflammatory or pro-fibrotic phenotypes in response to dynamic interactions with other cells, environmental factors and cytokine signatures.
"Language of intervention in bilingual children with Autism Spectrum D" by Connie Summers, Vanessa Smith et al.
Bilingual children, autism spectrum disorders, communication Summers, C., Smith, V., Mueller, V., 1 Alexander, V., & 1 Muzza, A. (2017). Language of intervention in bilingual children with Autism Spectrum Disorders. Perspectives of the ASHA Special Interest Groups, 2(SIG 1), 203-211. doi:10.1044/persp2.SIG1.203 Summers, Connie; Smith, Vanessa; Mueller, Vannesa; Alexander, Victoria; and Muzza, Amelie, "Language of intervention in bilingual children with Autism Spectrum Disorders" (2017).
Church Sermons for Oct 4
Arden United Methodist Church “God’s Gifted People: Biblical Foundations for Spiritual Gifts” by Rev. Bob Kells, based on the text Acts 1:4-8; Ephesians 4:1-7, 11-16 First Presbyterian Church EPC “1 Peter: Acceptable through Jesus Christ” by the Rev. Dr. Rufus T.
Cognición social y desinformación en el contexto de una campaña presidencial en Costa Rica
español El artículo se dirige a investigar la contribución de variables cognitivas, psicosociales y sociodemográficas en la aceptación y tendencia a compartir tanto mensajes desinformativos como verdaderos en el contexto de la campaña electoral presidencial costarricense durante el periodo 2021-2022.
First Impressions
The first half of this 2024 has been all about Next.js for me. Great timing since I noticed more and more companies requiring it, this felt like the natural next learning step for me. ⭐ The stars aligned and I landed a client for whom I'd be building a prototype using Next.js, which made me feel lucky to finally have the opportunity to use the framework in a "real product".
Noise Reduction and Localization Accuracy in a Mobile Magnetoencephalography System
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Nintedanib downregulates the profibrotic M2 phenotype in cultured monocyte-derived macrophages obtained from systemic sclerosis patients affected by interstitial lung disease | Arthritis Research & Therapy | Full Text
Fourteen SSc patients, followed by the Division of Clinical Rheumatology, University of Genova, Italy, were enrolled following the approval of the Ethical Committee of the Ospedale Policlinico San Martino (237REG2015, amendment number:002–28/05/2018) and the collection of the written informed consent. The patients were included according to the 2013 American College of Rheumatology (ACR)/European Alliance of Associations for Rheumatism (EULAR) criteria for SSc [23].
An adult with recurrent atypical teratoid rhabdoid tumor of the spine
Atypical teratoid/rhabdoid tumors (AT/RTs) are rare grade 4 CNS neoplasms as classified by the World Health Organization. While predominantly identified in the pediatric population, there are instances where AT/RTs can manifest in adulthood, challenging the traditional perception of their occurrence. In adults, AT/RT more frequently presents in the brain compared with the spine. AT/RT in the spine may exhibit a comparatively less aggressive nature, but this needs further validation.
Pathogens | Free Full-Text | Comparative Analysis of Human Hepatic Lesions in Dengue, Yellow Fever and Chikungunya: Revisiting Histopathological Changes in the Light of Modern Knowledge of Cell Pathology
This is an early access version, the complete PDF, HTML, and XML versions will be available soon.
Diagnostics | Free Full-Text | Description of Peripheral Blood Perfusion by Laser Speckle Contrast Analysis (LASCA) in ‘Early’ versus ‘Clinically Overt’ Systemic Sclerosis in Routine Clinics
Open AccessBrief Report by 1,†, 1,2,3,*,†, 4, 5, 1,2, 1,2, 5 and 5 1 Department of Rheumatology, Ghent University Hospital, 9000 Ghent, Belgium 2 Department of Internal Medicine, Ghent University Hospital, 9000 Ghent, Belgium 3 Unit for Molecular Immunology and Inflammation, Inflammation Research Center (IRC), Vlaams Instituut voor Biotechnologie (VIB), 9000 Ghent, Belgium 4 Biostatistics Unit, Department of Public Health and Primary Care, Ghent University, 9000 Ghent, Belgium 5 Laboratory of...
Involvement of the secosteroid vitamin D in autoimmune rheumatic diseases and COVID-19 - Nature Reviews Rheumatology
Authors and Affiliations Laboratory of Experimental Rheumatology and Academic Division of Clinical Rheumatology, Department of Internal Medicine and Specialties (DiMI), University of Genova–IRCCS San Martino Polyclinic Hospital, Genoa, Italy Maurizio Cutolo, Sabrina Paolino & Emanuele Gotelli Department of Internal Medicine, Department of Rheumatology, University Hospital Ghent, Ghent, Belgium Vanessa Smith Contributions M.C. and E.G. researched data for the article.
The Art of the Small (Programming) Victories
I was a bit hesitant to write this article since it could potentially boil down to "just write a list", but then I thought: it is more than just writing a list and it proved helpful to me, so why not. Listening to a podcast, an ultramarathon runner explained her method of mentally splitting the race into smaller chunks of 10-12kms (an ultramarathon can be around 100-130kms), in order to be able to have those "mini-goals" in between before making it through the finish line.
Systemic sclerosis
1. Bergamasco A Hartmann N Wallace L Verpillat P Epidemiology of systemic sclerosis and systemic sclerosis-associated interstitial lung disease. Clin Epidemiol. 2019; 11: 257-273 2. Morrisroe K Stevens W Sahhar J et al. The clinical and economic burden of systemic sclerosis related interstitial lung disease. Rheumatology (Oxford). 2020; 59: 1878-1888 3. Changes in causes of death in systemic sclerosis, 1972–2002. Ann Rheum Dis. 2007; 66: 940-944 4. Elhai M Meune C Boubaya M et al.
Multidisciplinary teams in the clinical care of fibrotic interstitial lung disease: current perspectives
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Important considerations for implementing MDTs in clinical practice There is a need to understand best practices of MDTs to implement them in the clinical setting. Previous diagnostic guidelines and surveys have shown that there is considerable heterogeneity in MDT meeting practices [25], and there are still unresolved controversies concerning MDT practices that will need to be addressed in future studies (table 4).
By Vincent Cottin Verified, Fernando Martinez, Fernando Martinez Verified, Vanessa Smith, Simon Walsh
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European Respiratory Review
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With The Tenant of Wildfell Hall, the Sydney Theatre Company gives us a Brontë adaptation for our moment
Sydney Theatre Company/Prudence Upton Review: The Tenant of Wildfell Hall, directed by Jessica Arthur for the Sydney Theatre Company “You know when it’s the autumn of 1827, and you’re sitting in a church, having the wrong sort of existential crisis?” Gilbert Markham (Remy Hii) asks the audience at the beginning of Emme...
With The Tenant of Wildfell Hall, the Sydney Theatre Company gives us a Brontë adaptation for our moment
Review: The Tenant of Wildfell Hall, directed by Jessica Arthur for the Sydney Theatre Company “You know when it’s the autumn of 1827, and you’re sitting in a church, having the wrong sort of existential crisis?” Gilbert Markham (Remy Hii) asks the audience at the beginning of Emme Hoy’s compelling theatrical adaptation of Anne Brontë’s The Tenant of Wildfell Hall (1848).
Epidemiology of interstitial lung diseases and their progressive-fibrosing behaviour in six European countries
Ole Hilberg, Anna-Maria Hoffmann-Vold, Vanessa Smith, Demosthenes Bouros, Maritta Kilpeläinen, Julien Guiot, Antonio Morais, Susana Clemente, Zoe Daniil, Despina Papakosta, Havard Fretheim, Sofia Neves, Tiago M. Alfaro, Katerina M.
CTLA4-Ig treatment induces M1–M2 shift in cultured monocyte-derived macrophages from healthy subjects and rheumatoid arthritis patients - Arthritis Research & Therapy
Research article Open Access Published: 24 December 2021 Maurizio Cutolo ORCID: orcid.org/0000-0002-5396-09321 na1, Stefano Soldano1 na1, Emanuele Gotelli1, Paola Montagna1, Rosanna Campitiello1, Sabrina Paolino1, Carmen Pizzorni1, Alberto Sulli1, Vanessa Smith2,3,4 & Samuele Tardito1 Arthritis Research & Therapy volume 23, Article number: 306 (2021) Cite this article Abstract Background In rheumatoid arthritis (RA), macrophages play an important role in modulating the immunoinflammatory...
Nintedanib downregulates the transition of cultured systemic sclerosis fibrocytes into myofibroblasts and their pro-fibrotic activity - Arthritis Research & Therapy
Abstract Background Circulating fibrocytes are an important source of fibroblasts and myofibroblasts, which are involved in fibrotic processes, including systemic sclerosis (SSc). The study aimed to investigate the effect of nintedanib (a tyrosine kinase inhibitor) in inhibiting the in vitro transition of circulating SSc fibrocytes into myofibroblasts and their pro-fibrotic activity. Methods Circulating fibrocytes were obtained from 18 SSc patients and 5 healthy subjects (HSs).
Evidences for a protective role of vitamin D in COVID-19
Evidences for a protective role of vitamin D in COVID-19 http://orcid.org/0000-0002-5396-0932Maurizio Cutolo1,2, Sabrina Paolino1 and Vanessa Smith3,4 1Laboratory of Experimental Rheumatology and Division of Rheumatology, University of Genoa, Genova, Liguria, Italy 2Clinical Rheumatology Unit, IRCCS San Martino Polyclinic Hospital, Genova, Italy 3Department of Rheumatology, Ghent University Hospital, Ghent, Belgium 4Department of Internal Medicine, Ghent University, Ghent, Belgium...
Guide to Virtual Dating During Quarantine
8 tips to create excitement and deepen meaningful connections virtually. Social distancing in our tech-driven world has us developing new forms of courtship at an unprecedented level. Now more than ever, individuals are turning to online dating platforms and digital communications to cultivate relationships. According to Statista.com, there were 30.4 million Americans using Internet dating services in 2019, and it is expected to increase to 35.4 million by 2024.
Tips and Tricks from a JavaScript (lover) Beginner
Photo by Artem Sapegin on Unsplash It’s been already 11 months since I decided to learn to code: I first started to study by myself a couple of hours after work and then enrolled into a 24-week coding bootcamp — I’m on week 13 now. I’m part of two communities full of people around the world with one thing in common: we are all taking our first steps into programming. I’m no expert, but even as a beginner I can give you some tips that have made the process smoother for me.
FlowerPower: The Bold Evolution of 500 Women Scientists
Almost four years ago, we wrote a pledge affirming our commitment to build a more inclusive society and scientific enterprise. On the heels of the November 2016 U.S. Presidential election, our pledge garnered more than 10,000 signatures in the first month and we harnessed the moment to build a global movement. We built a leadership team, defined our mission, and got to work making science more open, inclusive, and accessible. Vanessa Smith, an artist from Atlanta, Georgia, offered to design a logo.
Nailfold Videocapillaroscopy in Systemic Sclerosis-related Pulmonary Arterial Hypertension: A Systematic Literature Review
Nailfold Videocapillaroscopy in Systemic Sclerosis–related Pulmonary Arterial Hypertension: A Systematic Literature Review Vanessa Smith, Amber Vanhaecke, Els Vandecasteele, Miguel Guerra, Sabrina Paolino, Karin Melsens, Maurizio Cutolo The Journal of Rheumatology Jun 2020, 47 (6) 888-895; DOI: 10.3899/jrheum.190296
Gym in Amite, LA 70422
Everything You Need To Make It Happen Get to a healthier place at Anytime Fitness! Our friendly, professional staff is trained to help you along your fitness journey, no matter how much support you need. Membership includes a free, no-pressure fitness consultation, global access to more than 3,000 gyms, and always open 24/7 convenience. All in a welcoming club and supportive member community.
Might Nailfold Capillaroscopy Be a “Proxy” for Lung Involvement in Connective Tissue Diseases?
Lung involvement [pulmonary arterial hypertension (PAH)] and/or interstitial lung disease (ILD) are leading causes of death in systemic sclerosis (SSc)1. They also contribute significantly to the morbidity and mortality in other connective tissue diseases (CTD), such as Sjögren syndrome (SS), systemic lupus erythematosus (SLE), undifferentiated connective tissue disease (UCTD), mixed connective tissue disease (MCTD), and rheumatoid arthritis (RA)2,3,4.
Finding the Right Job as Someone With Fibromyalgia
Workers collaborating in a meeting. I got my first symptoms of fibromyalgia when I was 13 and was diagnosed at 17. I’ll be 30 this year. Through all that I loved going to school and I loved working. I held a part time job of 25 hours a week while going to school, with the exception of grade 12 when my fibro got so severe I could barely go to school. I had always wanted to go into the medical field and make a difference, but I realized I likely wouldn’t be able to make it through the schooling.
Pizza Rock, Sacramento
by Brooke Burgess and Vanessa Smith Like Sonny and Cher or Bonnie and Clyde, what is possibly a more dynamic combination than Pizza and Rock? With plenty of buzz about the food, the awards – co-owner Tony Gemignani won the World Pizza Cup in Naples, Italy – and décor, we couldn’t resist the opportunity to check it out with some good friends on a rainy workweek. Needless to say, we were not disappointed.
Imagine Dragons and SAP Join Forces to Introduce the One4 Project to Assist Refugees
October 12, 2015 by SAP News WALLDORF — With hundreds of thousands of refugees in urgent need of humanitarian assistance, particularly across the Middle East and Europe, Imagine Dragons and SAP SE (NYSE: SAP) are joining forces to introduce the One4 Project to support refugee relief efforts.
What's a #patiotakeover? ROCKSALT partners with Unknown, NoDa, Sugar Creek & Birdsong
By Vanessa Smith | | June 12, 2015 Views: News Briefing ROCKSALT is launching an event series called #patiotakeover. The series begins on June 21st (Father’s Day) and continues throughout the summer. The Facts #patiotakeover is a summer beer series where local breweries take over ROCKSALT’s patio on weekends. Breweries will offer beers for sale and give away goodies while Chef Jay’s crew feverishly shucks oysters.
Meet Cece Stronach, founder of #RuminateCLT
By Vanessa Smith | | August 18, 2015 Views: I’m constantly amazed at how many awesome people there are in Charlotte. There are an infinite amount of people here doing absolutely amazing and truly inspiring things. Meet my Twitter friend, turned real-life friend, Cece Stronach. She’s a visionary, avid cyclist, dream strategist and one of Charlotte’s game changers! She’s involved with so many things, including the Charlotte Creative Interventionists.
AT&T joins Charlotte internet arms race. Mayor Clodfelter is a U-verse subscriber
By Ted Williams | | June 16, 2015 Views: Yesterday, AT&T launched U-verse with GigaPower – a fancy, fast internet. Long story short, this is outstanding for us (consumers) as we now have powerhouses Time Warner Cable, Google and AT&T competing for our business. I don’t want to nerd out right now, but faster internet has all sorts of benefits for our city other than just lowering your Netflix buffering time so you can binge watch the new season of Orange is the New Black.
Letter to Potential Culinary Graduates
By Vanessa Smith | | May 14, 2015 Views: If you aspire to be the next food network star, you probably shouldn’t go to culinary school. Work in real kitchens first. See if you even like it. It is not a glamorous job. It’s working 15 hours a day. It’s sweaty. It’s gross. You will probably smell like a french fry or fish after your shift. You will become immune to it. You will have tattoos throughout your career, but not the inked ones, but scars from sheet pan burns and cuts from your chef’s knife.
Behind the Kitchen: A conversation with Adam Spears from Local Loaf
By Vanessa Smith | | May 11, 2015 Views: This is part of a chef interview series. View all interviews here. On a somewhat leisurely Monday afternoon, when 7th street market was winding down. I sat down with Chef Adam Spears of Local Loaf to talk about life and Charlotte and food. Not only did we talk about that, but I also found out how he likes to eat his eggs. More importantly, whoever cooks them better not screw them up.
Behind the Kitchen: A conversation with Michael Suppa from Vivace
By Vanessa Smith | | May 20, 2015 Views: This is part of a chef interview series. View all interviews here. On a sunny Wednesday afternoon, I had the opportunity to talk with Chef Michael Suppa of Vivace. While I was there, I was offered water, glass of wine or shot of tequila. I abstained from all of the above, but it made me love this place even more. If you live in Charlotte and haven’t been to brunch there, you truly live under a rock. Two courses, unlimited mimosas or bloody mary’s, only $25.
Suarez Bakery is made from scratch, a look behind the scenes.
By Gi Hallmark | | June 5, 2015 Views: I’ve visited many bakeries in my lifetime. They’re all very familiar with their beautiful pastry cases and unmistakable scents of baked flour and sugar. Suárez Bakery breeds this familiarity, but there’s also something different about Suárez.
Behind the Kitchen: A conversation with Jay Pierce from ROCKSALT
By Vanessa Smith | | June 19, 2015 Views: This is part of a chef interview series. View all interviews here. On a Monday afternoon, I met with Chef Jay Pierce of ROCKSALT restaurant to talk about chef life. He immediately scored brownie points when he brought over a taste of monkfish that he poached in whey. Come to find out he’s a New Orleans native, worked for Emeril Lagasse, likes ugly food and crunchy, funky salads. He also digs Vietnamese food. Can we be friends?
Behind the Kitchen: A conversation with Miles Payne from littleSpoon
By Vanessa Smith | | June 26, 2015 Views: This is part of a chef interview series. View all interviews here. On a Thursday afternoon I met with Chef Miles Payne of littleSpoon on Selwyn Ave. Admittedly, I’ve never eaten here, but after our conversation it has skyrocketed to the top of my dining list! We talked about how cool the chef community in Charlotte is right now, how tomatoes are awesome, and beer makes for a happy chef. Oh and apparently he’s tight with Chef Clark Barlowe. No big deal.
Behind the Kitchen: A conversation with Marc Jacksina from Earl's Grocery
By Vanessa Smith | | June 5, 2015 Views: This is part of a chef interview series. View all interviews here. On a Wednesday afternoon, I anxiously and nervously met Chef Marc Jacksina at Earl’s Grocery. I mean he’s the real deal, culinary badass. I thoroughly enjoyed talking with him. I learned that he’s a Yankee [like me!], his background consists of skateboarding and punk rock, he loves tacos [can we be friends?] and you better R-E-S-P-E-C-T his potatoes.
Beekeeping with Clark Barlowe
By Dana Boone | | July 22, 2015 Views: Today, I’d like to introduce you to Clark Barlowe – owner and executive chef at Charlotte’s Heirloom Restaurant. You may know him from features in the Charlotte Observer and Charlotte Magazine, or from a stint on Food Network’s battleground cooking show, “Chopped.” Then again, maybe you met him when you lucked into an Heirloom dining experience during Queen’s Feast. I know him from summer tennis camp at Cedar Rock Country Club in Lenoir, North Carolina.
More Than a Rounding Error
February 28, 2019 by Vanessa Smith Two decades ago I entered the tech sector, and I can still say it’s the best decision I ever made. The year was 1999, and I was working at a consulting firm. Just a few years out of college, and little did I know I was on a path that would propel me toward what’s now been 14 fantastic years and counting at SAP. Never could that 20-something-year-old have pictured herself heading up Sales for SAP’s Human Capital Management line of business in North America.
Behind the Kitchen: A conversation with David Lucarelli from The Cowfish
By Vanessa Smith | | May 29, 2015 Views: This is part of a chef interview series. View all interviews here. On a Wednesday afternoon, I sat down with Chef David from The Cowfish. I thoroughly enjoyed our conversation, and even after I was done recording, we continued talking. Which delayed putting in my lunch order, which then in turn made me late for my “real job”. #YOLO. I ended up ordering a side salad before my sushi and he totally freaked out thinking that’s all I ordered.
B-Sides: Marion Milner’s “A Life of One’s Own”
I rarely fail to remember my first encounter with a book—it usually becomes merged with the story of the book itself—so it is disconcerting to me to realize ... I rarely fail to remember my first encounter with a book—it usually becomes merged with the story of the book itself—so it is disconcerting to me to realize that I have no recollection of how I first latched onto Marion Milner’s A Life of One’s Own (1934). Someone must have told me to read it, or it could have cropped up in a footnote.
Keep Out, Or Else: Girls’ Diaries in Comics
Comics and the diaries of teenage girls don’t at first glance have that much to do with one another. After all, the latter tend to invoke the pastel ink of pens used to ... Comics and the diaries of teenage girls don’t at first glance have that much to do with one another. After all, the latter tend to invoke the pastel ink of pens used to dot i’s with hearts in vomit pink suburban bedrooms, while visions of sweaty, basement-dwelling fanboys still (somehow) cling to the former.
Nailfold videocapillaroscopy may aid in early diagnosis of systemic sclerosis
MADRID — Nailfold videocapillaroscopy demonstrated feasibility as a diagnostic tool for systemic sclerosis, particularly among patients with Raynaud’s phenomenon, according to findings presented at the Annual European Congress of Rheumatology.
Vitamin D deficiency and clinical correlations in systemic sclerosis patients: A retrospective analysis for possible future developments
Serum 25(OH)D deficiency was found to correlate with lung involvement, peripheral vascular, kidney and gastrointestinal Medsger’s DSS parameters and with seasonality In SSc patients. Supplementation with oral colecalciferol was found not effective in increasing 25(OH)D serum concentrations. Therefore, for successful replacement, supra-physiological vitamin D3 doses or programmed UVB light exposure should be tested.
The Plaza Midwood Bart Bandit is the hero Charlotte deserves
Last week we gleefully reported (albeit a bit sarcastically) on the appearance of Bart Simpson’s butt alongside Central Avenue. While most of us were amused by the cartoon’s full moon, other neighbors questioned the decency of the image, especially given its prominent location. Concerns were raised about what would become of the Bart butt and, more importantly, who would have to pay for its destruction.
The Importance Of Academic Electives
They teach you a critical perspective on other areas. One of my first year, undergraduate anthropology classes had a few medical students in it. They were being encouraged to try out other areas so that they had a better perspective of the world – which makes a lot of sense when you realise medical staff have to be able to deal with people from literally anywhere. You may not get exposed to this other set of variables during your time at university.
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