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Articles by Lin Yang
Digital financial inclusion and economic agglomeration: evidence from China’s first inclusive finance reform pilot zone
Abstract Digital financial inclusion supports sustainable development by reducing poverty and narrowing regional inequalities. However, gaps in digital access and literacy may limit its reach. This study examines the impact of a 2016 reform in China’s Lankao County using county-level data from 2000 to 2020 and a nonparametric synthetic control method. The results show that the reform significantly increased spatial concentration of economic activity.
Maternal and paternal burnout and social–emotional competence of children: the role of parental meta-emotions in a dyadic model
Abstract Objectives: Previous research on emotional socialization has primarily relied on mothers, limiting insight into paternal roles and cross-spousal association. To address this knowledge gap, we employed the actor–partner interdependence model to simultaneously examine maternal and paternal burnout and associations with child socioemotional competence (SEC) incorporating parental meta-emotion philosophy (PMEP). Methods: In this study, we analyzed 390 family triads (father–mother–child).
The Pulse Lives On: Nearly 1,200 Pieces of Feedback Shape the Product Loop as the 2026 EXEED International User Summit Kicks Off a New Round of Co-Creation
-- The 2026 EXEED International User Summit wrapped up on October 23. Running from Brand Launch Day on October 18 through Track Experience Day on October 19, the event—held under the theme "The Pulse Lives On"—drew 120 user representatives from 26 countries and regions, including the UK and Australia, who took part in the full program.
Biopsy-free versus biopsy-confirmed robot-assisted radical prostatectomy for prostate cancer: a systematic review and meta-analysis of an investigational strategy
Abstract Background: Routine prostate biopsy before radical prostatectomy (RP) provides histopathological confirmation and information for risk stratification but is associated with procedure-related morbidity. Advances in multiparametric magnetic resonance imaging (mpMRI) and prostate-specific membrane antigen positron emission tomography (PSMA PET) have prompted interest in highly selected biopsy-free pathways.
Silicon photonics provides a unified solution for all-distance optical communications
Abstract Optical links underpin global communications from chip-to-chip interconnects to transoceanic fibre networks. Conventional architectures remain distance-dependent: long-haul systems rely on coherent transmission for high spectral efficiency and capacity, while short-reach links favour intensity modulation due to hardware complexity and power constraints. This divide impedes scalability for AI-driven intra-data-centre traffic and low-latency, flexible cloud-to-edge connectivity.
ET 2027 Makes Its Track Debut at Zhejiang International Circuit as EXEED’s Track Experience Day Brings “The Pulse Lives On” to Life
-- The Track Experience Day at the 2026 EXEED International User Summit kicked off on October 19 at Zhejiang International Circuit in China, where the EXLANTIX ET 2027 made its track debut. A comprehensively upgraded version of the EXLANTIX ET, the ET 2027 brings upgrades in forward-thinking performance, avant-garde design and cutting-edge technology.
With October Sales Rising 14.9% Month-on-Month, EXEED Advances Its Premium Layout Via User Summit and Global Experience
-- In October 2026, EXEED’s global sales climbed 14.9% month on month. The 2026 EXEED International User Summit held that month offered global users a concentrated opportunity to experience the brand’s products and technologies. Feedback gathered from these experiences continues to accumulate and guides EXEED as it advances its premium market layout, giving consumers more tangible expectations for future luxury mobility.
Exploratory prediction of surgical outcomes in MRI-negative epilepsy using preoperative individualized morphometric networks
CONFLICT OF INTEREST STATEMENT The authors have no conflicts of interest to declare. DISCLOSURE Declaration of generative AI in scientific writing: This article does not use an artificial intelligence (AI) generator to generate text. DATA AVAILABILITY STATEMENT The datasets generated and analyzed during the current study are available from the corresponding author upon reasonable request. Due to privacy and ethical considerations, the data are not publicly accessible.
EXEED Hosts 12 Track Experience Events with Global Users to Validate Its Performance DNA on the Track
-- EXEED held a track experience day in Zhejiang as part of the 2026 EXEED International User Summit, under the theme “The Pulse Lives on.” The EXLANTIX ET 2027, EXEED RX 2027, and EXEED RX MY[1] made their track test-drive debuts at the event. More than 100 user representatives and partners from around the world gathered to witness EXEED’s 12th track-running session at a professional circuit. The track provides an extreme test of vehicle performance.
RX 2027 Makes Its Global Track Debut Alongside Users at “China’s Nürburgring,” Continuing EXEED’s Racing DNA
-- During the 2026 EXEED International User Summit, the EXEED RX 2027 made its global track debut alongside users from around the world. Users, media representatives, and partners from around the world gathered at Zhejiang International Circuit to drive the vehicle around the track and experience the power delivery and cornering performance of this premium five-seat SUV. The RX 2027’s hybrid powertrain and all-wheel-drive system were key highlights of the track sessions.
An engineered, compact Cas12m variant for multiplexed gene activation in vivo
Abstract Achieving coordinated CRISPR-based transactivation (CRISPRa) regulation in vivo remains challenging, as the requisite genetic elements frequently exceed the packaging capacity of AAV vectors. Here we report the identification and engineering of the Cas12m protein family, a naturally nuclease-dead CRISPR system that possesses intrinsic self-processing activity for its precursor crRNA. We develop an optimized variant, denCas12m, and leverage it in the smCRISPRa platform.
Creator 1.0: Phylogeny-Guided Stagewise Pretraining for Plant Genome Foundation Models across 1,000 Species
Abstract Genomic language models have advanced DNA sequence analysis, but their applicability to plant-specific tasks and representation changes during pretraining remain poorly characterized. Here, we present Creator 1.0, a 2-billion-parameter parameter plant genome foundation model pretrained on 1,000 plant genomes using phylogeny-guided stagewise pretraining (PGSP). Training comprised 83 consecutive stages and produced 52 cumulative checkpoints associated with distinct plant orders.
Electrification and socioeconomic pathways to women’s empowerment: evidence from renewable energy transitions in the Global South
ABSTRACT Electrification is central to sustainable development, yet energy poverty disproportionately affects women. This paper examines how electrification can create socioeconomic pathways to women’s empowerment amid renewable energy transitions in the Global South.
ET 2027 Puts SIVP to the Test at 2026 EXEED International User Summit
-- From October 19 to 20, the 2026 EXEED International User Summit hosted its track experience days at Zhejiang International Circuit. There, EXEED put the ET 2027’s Super Intelligent Valet Parking (SIVP) system to the test, giving guests a firsthand look at its capabilities. While acceleration, handling and braking were the focus of the on-track sessions, the SIVP demonstration shifted the spotlight to a more everyday aspect of driving: parking and vehicle pickup.
Calpain-5 mediates STIP1 degradation via triggering N-degron pathway to suppress epithelial ovarian cancer progression and CAPN5 low -STIP1 high status indicates Pimitespib susceptibility
Abstract Rapid progression is considered the major contributor to the poor prognosis of epithelial ovarian cancer (EOC), while the underlying mechanism remains elusive. Herein, we identified that Calpain-5 (CAPN5), a well-known protease, was significantly downregulated across various types of EOC, and acted as a protective indicator for prognosis.
Rooted in Perpetua, EXEED Unveils Its All-New Design Language Future Luxury — EX9, EX8, EX7 and MPV Concept Make a Joint Appearance
-- The “All-New Design Language Launch” segment of the 2026 EXEED International User Summit took place at the Shanghai R&D Center. Centered on the theme “The Future Luxury”, the event showcased EXEED’s brand-new family design language. Brand Exterior Designer Christo Pavlidis and Chief Designer Juan Manuel Diaz took the stage one after another to elaborate on how the new design language was realized on the first batch of production-intent models: the ES GT, EX9, EX8, EX7 and MPV Concept.
From Ocean Inspiration to Future Luxury: EXEED Unveils Its New Design Language with ES GT and ET 2027
-- On October 18, the "New Design Language Launch" was held at the Chery Global Technology Innovation Center in Shanghai as part of the 2026 EXEED International User Summit. Under the theme "The Future Luxury," EXEED design stylist Christo Pavlidis and Chief Designer Juan Manuel Diaz jointly presented the brand's new Future Luxury design language, rooted in its Perpetua design philosophy.
OMODA9 MY Makes Its Track Test Debut, Unveiling the Performance Pedigree of a Flagship SUV
-- Held in China from October 18 to 23, the 2026 Chery International User Summit featured its flagship Circuit Track Day on October 19 at Zhejiang International Circuit. Nearly 100 users, partners and industry media representatives from across the globe gathered to witness the performance prowess of future luxury. Media representatives and partners from the UK, Australia, Hungary, Bulgaria and Romania joined the test drive.
Designing the Future: EXEED Unveils Its New "Future Luxury" Design Vision
-- The New Design Language Launch took place at EXEED’s Shanghai R&D Center during the 2026 EXEED International User Summit. Centered on the theme of “The Future Luxury”, the session brought together EXEED designers Christo Pavlidis and Chief Designer Juan Manuel Diaz to unpack the brand’s all-new Future Luxury design vision. Rooted in the Perpetua design philosophy, EXEED envisions continuous technological advancement and iterative design evolution.
Small-cell lung cancer transformation approximately four years after surgery and adjuvant therapy for EGFR-mutant lung adenocarcinoma: a case report
Abstract Background: Transformation of epidermal growth factor receptor (EGFR)-mutant non-small cell lung cancer (NSCLC) to small-cell lung cancer (SCLC) is a recognized mechanism of acquired resistance to EGFR tyrosine kinase inhibitors (EGFR-TKIs) and is associated with poor clinical outcomes. The optimal treatment strategy for transformed SCLC remains uncertain.
From Static Showcase to First Track Test Drive, ET FL Premieres at 2026 EXEED International User Summit
-- From October 18 to 23, the 2026 EXEED International User Summit will be held under the theme "The Pulse Lives on". The ET FL will be on static display at the brand launch on October 18, and undergo its inaugural track test drive during the Track Experience Day on October 19 and 20. From design details and cutting-edge technology to performance experience, the ET FL will showcase EXEED’s vision of Future Luxury mobility for global users.
Range-Extended & BEV Models Make Dual Debut — ET FL Takes Its Inaugural Track Test Drive at 2026 EXEED International User Summit
-- From October 18 to 23, the 2026 EXEED International User Summit will be held under the theme "The Pulse Lives on". The ET FL will be on static display at the brand launch on October 18, and undergo its inaugural track test drive during the Track Experience Day on October 19 and 20. From design details and cutting-edge technology to performance experience, the ET FL will showcase EXEED’s vision of Future Luxury mobility for global users.
EX9 to Headline New Vehicle Debuts as EXEED Reveals Design Language Launch Highlights at the 2026 International User Summit
-- From October 18 to 23, the 2026 EXEED International User Summit will be held in China under the theme “The Pulse Lives on”. As a core segment of the summit, the EXEED Design Language Launch will take place in Shanghai on October 18, showcasing the brand’s latest interpretation of Future Luxury. The all-new EX9, engineered under this design language, will also make its on-site debut.
Association between serum 25-hydroxyvitamin D levels and thyroid function alterations in hospitalized adults: a retrospective cross-sectional study
Abstract Background: Thyroid function abnormalities and low vitamin D status are common in hospitalized adults, but evidence on their association remains limited and inconsistent. Methods: We conducted a retrospective cross-sectional study of 225 adult inpatients between January 2020 and January 2025. Serum 25-hydroxyvitamin D [25(OH)D] and thyroid function indicators were measured during the same admission.
Contribution of chemical components to cloud condensation nuclei prediction across multiple continental sites
Abstract Aerosol–cloud interactions represent a major uncertainty in climate projections. Cloud condensation nuclei (CCN) are particles upon which cloud droplets form, yet in situ CCN measurements remain scarce. Aerosol chemical component exerts important control over CCN activity. It remains unclear how reliably aerosol chemical composition predicts CCN number concentration (NCCN).
Countdown Starts for the Track Experience at the 2026 EXEED International User Summit; First Track Test Drives of ET FL, RX FL and RX MY Ready to Launch
-- From October 18 to 23, the 2026 EXEED International User Summit, themed "The Pulse Lives on," will take place in China. As a core session of the summit, Track Experience Day is scheduled for October 19 at Zhejiang International Circuit. Three models — EXLANTIX ET FL, RX FL and RX MY — equipped with three powertrain options including BEV, REEV and PHEV, will hit the track together in front of over 100 users and partners from global markets.
Updated systematic review and meta-analysis comparing Myval versus Sapien 3 transcatheter heart valves in severe aortic stenosis: focus on early and one-year mortality
Transcatheter aortic valve implantation (TAVI) is a guideline-recommended treatment for severe aortic stenosis (AS). While the balloon-expandable Edwards Sapien 3 valve has long been the benchmark, the newer Myval valve has emerged as a potential alternative. Comparative data on mid-term survival, specifically one-year all-cause mortality, are lacking but crucial for clinical evaluation.
Metabolic abnormality and advanced AJCC stage at prostate cancer diagnosis: a single-center retrospective cross-sectional study
Abstract Background: Metabolic status and body mass index (BMI) capture related but distinct host characteristics. We examined whether metabolic abnormality was associated with American Joint Committee on Cancer (AJCC) stages III–IV at prostate cancer diagnosis after accounting for BMI category. Methods: This retrospective cross-sectional study included 324 consecutive patients newly diagnosed at one center from July 2015 to March 2026.
An open vision-language model for diverse medical applications
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Abstract Artificial intelligence has high potential for impact in healthcare applications, but its training and deployment are challenging due to diverse data, a complex spectrum of possible tasks and important privacy needs. High-performing foundation models that enable data-efficient fine-tuning for diverse downstream tasks can meaningfully accelerate development in this domain. We introduce MedGemma, a collection of medical vision-language foundation models based on Gemma 3.
By Sahar Kazemzadeh, Fereshteh Mahvar, Atilla P. Kiraly, Timo Kohlberger, Chufan Gao, Ronnachai Jaroensri, Shawn Xu, Cian O Hughes, Cían Hughes, Charles T. Lau, Justin Chen, Tiffany Chen, Jeremy Lai, Samuel Schmidgall, Lu Yang, Kejia Chen, Kenneth A Philbrick, Mercy Asaa Asiedu, Howard Hu, Howard Yang, Richa Tiwari, Sunny Jansen, Preeti Singh, Yubin Kim, Daniel McDuff, Catherine Kozlowski, Shreya pathak, Nino Vieillard, Sarah Perrin, Tatiana Matejovicova, Thomas Mesnard, Geoffrey Cideron, Michelle Casbon, Jean-Baptiste Alayrac, Vlad Feinberg, Sebastian Borgeaud, Cassidy Hardin, Robert Dadashi, Léonard Hussenot, Armand Joulin, Clement Farabet, Joelle Barral, Tris Warkentin, Jonathon Shlens, David Fleet Verified, Shekoofeh Azizi, Omar Sanseviero, Gus Martins, Phoebe Kirk, Anand Rao, Yossi Matias, Katherine Chou, Avinatan Hassidim, Dale Webster, Shravya Shetty, Yun Liu, David Steiner, Rory Pilgrim, Daniel Golden Verified, Lin Yang, Andrew Sellergren, Madeleine Traverse, Fayaz Jamil, Liron Yatziv, Bram Sterling, Stefanie Anna Baby, Susanna Maria Baby, Per Bjornsson, Shashir Reddy, Ryan Brush, Bashir Sadjad, Ines Mezerreg, Rachelle Sico, Aishwarya Kamath, Johan Ferret, Ramona Merhej, Alexandre Ramé, Morgane Riviere, Louis Rouillard, Jean-bastien Grill, Sabela Ramos, Edouard Yvinec, Elena Buchatskaya, Dmitry Lepikhin, Alek Andreev, Olivier Bachem, Victor Cotruta, Kavi Goel, Can Kirmizibayrak
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Nature
Verified
EXEED to Unveil Nearly 20 Green Technology and Ecosystem Innovations at 2026 International User Summit
-- EXEED will unveil nearly 20 green technology and cross-industry ecosystem innovations during the 2026 EXEED International User Summit, taking place from October 18 to 24 in China. The planned showcases will focus on new energy mobility, intelligent technology applications and ecosystem experiences, giving users, media and industry partners a closer look at EXEED's latest developments across electrification, AI and future mobility scenarios.
EXEED Sponsors the Davis Cup Morocco Leg, with Three Star Models Appearing at Rabat’s Courts
-- The 2026 Davis Cup World Group Qualifiers took place on September 19–20 on the clay courts of the USCM Club in Rabat, Morocco. Host nation Morocco defeated Nigeria 4-0 in a clean sweep, securing its spot in the Davis Cup World Group I Play-offs scheduled for February 2027. As an official sponsor of the 2026 Davis Cup, EXEED showcased three flagship models — the EXLANTIX ET, EXLANTIX ES and EXEED RX — in a dedicated display zone.
EXEED International User Summit: Dual Launch of Design Refresh and Performance Experience
-- The 2026 EXEED International User Summit is set for October 18 under the theme “The Pulse Lives on”. It will deliver a multi-dimensional showcase focused on global user co-creation, avant-garde design, track performance and brand ecosystem, highlighting EXEED’s latest advances in premium mobility, cutting-edge technologies and global user operations.
Zona incerta somatostatin + neurons modulate seizure progression through hypothalamic circuits
Abstract GABAergic neurons critically regulate epileptic seizures, yet circuit mechanisms mediated by subtype-specific GABAergic neurons in the zona incerta (ZI) remain unclear. Here we reveal the essential role of ZI somatostatin+ GABAergic neurons in seizure modulation in the mouse hippocampal kindling model. In vivo Ca2+ fiber photometry and optogenetics show that ZI GABAergic neurons are gradually activated during seizure progression.
Early identification of Prader-Willi syndrome in newborns using facial phenotype-based machine learning
Abstract Existing facial models for Prader-Willi syndrome (PWS) demonstrate limited accuracy in newborns with subtle facial dysmorphism. Photographs of children from a public platform (training cohort) and of newborns from Children’s Hospital of Fudan University (validation cohort) were used for feature comparison. Models were developed using six algorithms with three feature sets (Complete-, Top-10, and ClinSel-) in the training cohort.
The association between vestibular-related symptoms and depressive symptoms: a systematic review and meta-analysis
Abstract Vestibular-related symptoms are increasingly recognized as being significantly associated with depressive symptoms, yet the strength and consistency of this association remain unclear due to conflicting evidence across studies. It is also uncertain whether this relationship reflects general psychological distress or is specific to clinically significant depressive symptoms.
Application of the BOPPPS-CBL model in pre-employment training for emergency ancillary staff during the COVID-19 pandemic
Abstract Our emergency response team needed to quickly train newly recruited stretcher bearers and ambulance drivers to join the workforce during the COVID-19 pandemic. In our country, the absence of standardized pre-employment training programs for them has created an urgent need to develop an effective training method.
Associations between photograph-derived postural deviations and self-reported pelvic pain locations during pregnancy
Abstract Photograph-derived posture assessment may provide a low-burden way to describe musculoskeletal alignment during pregnancy, but its relationship with pelvic pain location is unclear. This exploratory retrospective observational study linked standardized early-pregnancy photographs with pre-randomization questionnaire data from 118 pregnant women. An automated photograph-based system classified 13 postural features into three ordinal levels.
Chinese manufacturers look to Egypt as a base for exports
by LIN Yang CAIRO - Egypt could provide Chinese manufacturers with a base for serving overseas markets and, eventually, exporting some products back to China, according to the chairman of the China Committee at the Egyptian Businessmen's Association. Ahmed Mounir Ezz El-Din said Egypt's location could help manufacturers reach African and Middle Eastern markets and respond to overseas buyers seeking faster deliveries.
A retinoic acid autoregulatory loop governing prefrontal–motor arealization
Abstract The frontal lobe comprises the prefrontal association cortex (PFC), which supports complex cognition and goal-directed behaviour, and the motor cortex (MC), which executes movement1,2,3,4,5,6,7,8,9,10,11,12,13,14. The establishment of distinct regional identities and connections along the sensorimotor-to-association axis provides a fundamental scaffold for cortical areal organization and function15,16,17,18,19.
Potential therapeutic targets for common mental disorders identified through Mendelian randomization and colocalization
Abstract Mental disorders are a major global health challenge, exacerbated by a narrow range of effective treatments and inadequate responses. The discovery of novel drug targets is necessary.
Post-stroke sarcopenia as a neuromuscular disorder: a mini review of neural mechanisms and clinical implications
Abstract Background: Post-stroke sarcopenia represents a distinct neuromuscular disorder characterized by progressive muscle loss and functional decline. Unlike age-related sarcopenia, stroke-induced muscle wasting involves specific neural mechanisms originating from central nervous system injury. Objective: To systematically review the neural mechanisms underlying post-stroke sarcopenia and synthesize evidence on its clinical implications, diagnostic approaches, and therapeutic interventions.
A novel bispecific antibody targeting Frizzled7/PD-L1 overcomes NSCLC resistance to atezolizumab by reprogramming tumor microenvironment
Abstract Immunotherapy efficacy in non-small cell lung cancer (NSCLC) remains limited, and aberrant activation of the Wnt/β‑Catenin pathway plays a significant role. However, the precise involvement of its receptor, Frizzled7 (Fzd7), in immune checkpoint inhibitor (ICI)-resistance remains unexplored.
An integrative framework for early estimation of global crop yields demonstrated under large-scale disruptions
Abstract Expectations of global crop yields, especially in major production countries, strongly influence crop-export policies and global food security, especially during national and global disruptions. Timely yield estimation remains difficult at the global scale because of large differences in crop phenology, environmental conditions and agricultural practices.
Global patterns and demographic drivers of hearing loss attributable to otitis media, 1990–2023
Citation: Xue Y, Ma H, Yang L, Liu Q (2026) Global patterns and demographic drivers of hearing loss attributable to otitis media, 1990–2023. PLoS One 21(8): e0356787. https://doi.org/10.1371/journal.pone.0356787 Editor: Rohit Ravi, Manipal Academy of Higher Education, INDIA Received: January 20, 2026; Accepted: August 8, 2026; Published: August 28, 2026 Copyright: © 2026 Xue et al.
2′-Fucosyllactose attenuates estrogen-deficiency-associated bone loss and intestinal dysfunction in ovariectomized rats
DATA AVAILABILITY STATEMENT The data that support the findings of this study are available from the corresponding author upon reasonable request. REFERENCES 1, , and , Osteoporosis pathogenesis and treatment: existing and emerging avenues. Cell Mol Biol Lett 27: 72 (2022). https://doi.org/10.1186/s11658-022-00371-3. 2, and , Classification of osteoporosis. Indian J Orthop 57: 49–54 (2023). https://doi.org/10.1007/s43465-023-01058-3.
Pro4S: Prediction of protein solubility by fusing sequence, structure, and surface
CONFLICT OF INTEREST STATEMENT The authors declare no conflict of interest. DATA AVAILABILITY STATEMENT The sequences of the training and test sets, along with their corresponding AlphaFold2-predicted structures, are available at our GitHub repository: https://github.com/TEKHOO/Pro4S. Installable source code, associated guidelines, various custom scripts, and interactive data analysis notebooks are available at GitHub: https://github.com/TEKHOO/Pro4S.
Loss of SHP1 in Spinal Astrocytes Triggers T-Lymphocyte Infiltration and Nociceptive Hypersensitivity
Advanced Hub Main Navigation Menu Lan-Xing Yi, Lin Yang, and Kang-Li Wang contributed equally to this work.
Spatio-temporal patterns and environmental controls of soil organic carbon stocks in global tidal wetlands since 2009
Abstract Tidal wetlands are important blue carbon ecosystems, yet global estimates of soil organic carbon (SOC) stocks and dynamics across mangroves, salt marshes, and tidal flats remain unclear. Using 42,154 records and 63 environmental covariates, we generate global tidal wetland SOC maps for two periods (2009-2014 and 2015-2020) at three depths.
The tubular surfaces generated by great circular surfaces in the three-sphere
Advanced search Applicable Analysis An International Journal Latest Articles Submit an article Journal homepage Full Article Figures & data References Citations Metrics Reprints & Permissions Read this article /doi/full/10.1080/00036811.2026.2689698?needAccess=true Abstract We construct a tubular surface generated by a great circular surface in the three-sphere. This tubular surface is the great circular surface when the radius function is equal to 1.
Synthesis of High-Whiteness Ultrafine Anhydrite from Phosphogypsum: A New Method for Activating Persulfate in the Transformation Process of Sulfuric Acid–Persulfate Medium Click to copy article link Article link copied!
Abstract Click to copy section linkSection link copied! Phosphogypsum (PG) is a solid waste generated during the wet-process production of phosphoric acid, which severely restricts the development of the phosphorus chemical industry. The conventional crystal transformation process of PG suffers from high temperature, high energy consumption, and limited improvement in product whiteness.
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