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Xia LIN

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Articles

Improvement of precise large-fragment deletion with a versatile nuclease prime editor

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By Xiangyang Li, Wenjun Sun, Gefei Wang, Xinpeng Ma, Mengyao Dai, Yang Zhao, Liqun Lei, Xuechao Cai, Shuaifeng Li, Shisheng Huang, Xingxu Huang, Xia LIN, Tingbo Liang
| Nature Verified
Dear Editor, Among 241,074 known pathogenic or likely pathogenic human genetic variants, ~27.7% were deletions or replacements (i.e., insertions following deletions)1. Many abnormal deletions and replacements involved relatively large DNA fragments, including ~953 variants with deletions exceeding 1 kb (Supplementary Fig. S1a), posing a major challenge for genome editing.
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Integrative Multi-Omics Analysis Reveals Mechanisms Underlying Floral Organ Development and Flower Color Formation in Renanthera coccinea , a Rare Tropical Orchid

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By Xin Yang, Xia LIN, Xiaoyang Wang
| Preprints.org
You are already at the latest version The genus Renanthera is valued for its fiery-red floral coloration and distinctive spider-like floral architecture; however, the molecular mechanisms underlying floral organ specialization and perianth color differentiation remain poorly understood. In this study, using integrated morphological, transcriptomic, and metabolomic analyses of R.
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Identification of key control points in instrument reprocessing of hospital central sterile supply department and its association analysis with surgical site infection

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By Xia LIN, Jie Wu
| Frontiers in Public Health Verified
Abstract Background: The Central Sterile Supply Department (CSSD) plays a crucial role in preventing healthcare-associated infections through proper instrument reprocessing. However, critical control points in the reprocessing workflow and their direct association with surgical site infection (SSI) remain inadequately characterized.
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