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Articles by Xiaoli Lu
Writing to Give Sense in an Unfolding Crisis: Examining Senior Executives' Pishi in the Chinese Administrative System
Conflicts of Interest The authors declare no conflicts of interest. Data Availability Statement To keep the confidentiality of participants, data generated during the study is not publicly available. Supporting Information Filename Description jccm70248-sup-0001-Appendix.docx30.1 KB Supporting File 1 jccm70248-sup-0002-Appendix.docx16.3 KB Supporting File 2 References 2010. “Narrative Construction as Sensemaking: How a Central Bank Thinks.” Organization Studies 31, no. 3: 349–367. , , and . 2005.
Phase separation–based HTS identifies cobimetinib as a YAP-TEAD inhibitor that suppresses hyperactivated YAP-induced cancer progression
Editor’s summary YAP/TAZ are key effectors of the Hippo pathway, which regulates an array of biological processes, including cell proliferation, survival, apoptosis, and tissue homeostasis. The binding of YAP/TAZ to the transcription factor TEAD induces the transcription of genes that promote cancer growth. Yang et al.
Coastal tourism destinations’ resilience framework-based assessment to climate change-caused hazards: a cross-country study
ABSTRACT Securing the resilience of coastal tourism destinations (CTDs) to climate change is becoming increasingly indispensable, particularly in arid countries. Nevertheless, relatively little research has been conducted to examine how resilient CTDs are to climatic fluctuations. Thus, this study aims to address this gap by assessing how CC-resilient CTDs are. The RCTDs framework was developed to evaluate CTDs’ resilience to CC.
Structural basis for substrate recognition mechanism of human SLC26A7 - Nature Communications
Abstract Solute carrier family 26 (SLC26) mainly mediates transmembrane transport of various anion ions, including chloride and other halide ions, bicarbonate, oxalate, and sulfate. Many severe hereditary human diseases are correlated with SLC26 protein mutations. Here we report cryo-EM structures of human SLC26A7 in apo and iodide binding states. We identify non-canonical binding site for halide ions in SLC26A7.
Structural basis of auxin binding and transport by Arabidopsis thaliana AUX1
Abstract Indole-3-acetic acid (IAA), the major form of auxin, is essential for plant growth. Auxin-resistant 1 (AUX1), the first identified auxin importer, plays a crucial role in polar auxin transport (PAT). Here we present cryo-EM structures of Arabidopsis thaliana AUX1 in the IAA-free and IAA-bound states. AUX1 exists as a monomer that contains 11 transmembrane helixes (TMs). TMs 1-5 and 6-10 constitute the two halves of a classic LeuT-fold, and TM11 interacts with both halves at the interface.
Hydrogen Bond Network Assisted Ultrafast Ion Transport of Anion Exchange Membrane Grafting with Covalent Organic Frameworks for Hydrogen Conversion
Conflict of Interests The authors declare no conflict of interest. Supporting Information Filename Description anie202503372-supp-0001-SupppMat.docx51.4 MB Supporting information References 1, , , Angew. Chem. Int. Ed. 2025, 64, e202418324. 2, , , , , , , , , , , Adv. Mater. 2024, 36, 2404981. 3, , , , , , J. Mater. Chem. A 2021, 9, 23485–23496. 4, , , , ACS Energy Lett. 2023, 8, 4043–4051. 5, , , , , , , , , , Angew. Chem. Int. Ed. 2023, 62, e202311509. 6, , , , J. Energy Chem. 2025, 102, 670–702.
Spatial and Temporal Distribution Patterns of Fish in Large Deep-Water Lakes and Their Association with Environmental Factors Assessed Through Hydroacoustic Methods: A Case Study of Qiandao Lake, China
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Study on Transport and Temperature Characteristics of β-Ga2O3 Based Diode Controlled by Varying Anode Work Function
Preprint Article Version 1 This version is not peer-reviewed Version 1 : Received: 21 October 2024 / Approved: 21 October 2024 / Online: 21 October 2024 (13:49:41 CEST) He, Y.; Sheng, B.; Lu, X.; Chen, G.; Liu, P.; Zhou, Y.; Wang, X.; Chen, W.; Wang, L.; Yang, J.; Zheng, X.; Ma, X.; Hao, Y. Study on Transport and Temperature Characteristics of β-Ga2O3 Based Diode Controlled by Varying Anode Work Function. Preprints 2024, 2024101599.
Multiconfigurational Actinide Nitrides Assisted by Double Möbius Aromaticity
Multiconfigurational Actinide Nitrides Assisted by Double Möbius Aromaticity Understanding the bonding nature between actinides and main-group elements remains a key challenge in actinide chemistry due to the involvement of f orbitals. Herein, we propose a unique “aromaticity-assisted multiconfiguration” (AAM) model to elucidate the bonding nature in actinide nitrides (An2N2, An= Ac, Th, Pa, U).
Molecular Mechanisms of Na+-driven Bile Acid Transport in Human NTCP
Abstract Human Na+ taurocholate co-transporting protein (hNTCP) is a key bile salt transporter to maintain enterohepatic circulation and is responsible for the recognition of hepatitis B and D viruses (HBV/HDV). Despite landmark cryo-EM studies revealing open-pore and inward-facing states of NTCP stabilized by antibodies, the transport mechanism remains largely unknown.
Association and mediation between educational attainment and respiratory diseases: a Mendelian randomization study - Respiratory Research
In Mendelian randomization research, genetic information is usually used as an instrumental variable (IV) due to their random distribution in humans and robust associations with the exposure and outcome variables being investigated. EA was assessed causally associated with lung cancer, FEV1, FVC, FEV1/FVC and asthma using two-step Mendelian randomization analysis. All GWAS summary statistics were gathered from a public GWAS website (https://gwas.mrcieu.ac.uk/) for the purposes of these analyses.
Self‐Enhancement of Perfluorinated Sulfonic Acid Proton Exchange Membrane with Its Own Nanofibers
Conflict of Interest The authors declare no conflict of interest. Supporting Information Filename Description adma202305711-sup-0001-SuppMat.pdf917.7 KB Supporting Information References 1, , , , , , , , , , , , , , Nature 2021, 595, 361. 2a) , , , , , , , , , , , , , , , , , Energy Environ. Sci. 2021, 14, 4948; b) , , , , , , , Science 2017, 357, 479. 3, , , , , , , , , , , , , , , Nature 2016, 532, 480. 4a) , , Nature 2001, 414, 345; b) , , , , , , , , , Nat. Energy 2022, 7, 153. 5a) , , , , , , J.
Microcrystalline-Induced Physical-Cross-linking toward a High Performance Hyper-Branched Anion Exchange Membrane
Download Hi-Res ImageDownload to MS-PowerPointCite This:Macromolecules 2024, XXXX, XXX Terms & Conditions Most electronic Supporting Information files are available without a subscription to ACS Web Editions. Such files may be downloaded by article for research use (if there is a public use license linked to the relevant article, that license may permit other uses).
Molecular Mechanisms of Na+-driven Bile Acid Transport in Human NTCP
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How a single mutation alters the protein structure: a simulation investigation on protein tyrosine phosphatase SHP2
How a single mutation alters the protein structure: a simulation investigation on protein tyrosine phosphatase SHP2† Protein tyrosine phosphatase SHP2 is a key regulator modulating several signaling pathways. The oncogenic mutation E76K in SHP2 releases the enzyme from an autoinhibited, closed conformation into an active, open conformation.
Intrinsic Auxeticity and Negative Piezoelectricity in Two-dimensional Group-IV dipnictide monolayers with In-plane Anisotropy
Intrinsic Auxeticity and Negative Piezoelectricity in Two-dimensional Group-IV dipnictide monolayers with In-plane Anisotropy Yue Zhao, Gaoyang Gou, Xiaoli Lu and Yue Hao Abstract Two-dimensional (2D) van der Waals (vdW) layered materials with orthorhombic symmetry and distinct planar crystallographic lattices up to monolayer limit, can potentially display the in-plane anisotropy and diversed functionalities arised from the structural anisotropy.
Construction of Reduced Graphene Oxide Wrapped Yolk-Shell Vanadium Dioxide Sphere Hybrid Host for High-Performance Lithium-Sulfur Batteries
Construction of Reduced Graphene Oxide Wrapped Yolk-Shell Vanadium Dioxide Sphere Hybrid Host for High-Performance Lithium-Sulfur Batteries Owing to the considerable theoretical energy density, lithium-sulfur batteries have been deemed as a competitive candidate for next-generation energy storage devices. However, its commercialization still depends on the moderation of shuttle effect and the conductivity improvement of the sulfur cathode.
Simple and efficient nonlinear polarization evolution mode-locked fiber laser by three-dimensionally manipulating a polarization beam splitter
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