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Articles by Xiaorui Chen
Long-term nitrous acid evolution modulates ozone and secondary aerosol variations in global megacities
Abstract Nitrous acid (HONO) is a crucial urban source of HOx radicals, promoting surface ozone (O3) and secondary fine particle (PM2.5) formation, yet its long-term evolution and air-quality impacts remain poorly constrained. Here, using a deep neural network established on worldwide field campaigns, we reconstruct global surface HONO distributions.
Altering the carbohydrate-binding specificity of the legume lectin FRIL through structure-guided engineering - Nature Communications
Abstract FRIL is a legume lectin from the hyacinth bean that has broad-spectrum antiviral activity. A distinctive trait of FRIL among similar mannose/glucose-specific legume lectins is that FRIL shows specificity for complex type N-glycans. We postulate that an extended binding site on FRIL facilitates this ligand selectivity.
Isotopic constraints on the origin of reactive chlorine in the troposphere
Abstract Oceanic and anthropogenic processes, such as sea-salt emissions and combustion activities, release substantial amount of reactive chlorine into the troposphere, affecting air quality, ozone depletion, and climate change. However, distinguishing between these sources for reactive chlorine remains challenging. Here, we establish isotopic constraints on the origin of tropospheric reactive chlorine using chemical ionization mass spectrometry to analyze nitryl chloride (ClNO2).
Nb‐Doping‐Derived Fe Vacancy Boosting Reversible Reaction Kinetics of Na4Fe3(PO4)2P2O7 Cathode for Enhanced Sodium Storage
Conflicts of Interest The authors declare no conflicts of interest. Data Availability Statement The data that support the findings of this study are available from the corresponding author upon reasonable request.
Structures of butyrophilin multimers reveal a plier-like mechanism for Vγ9Vδ2 T cell receptor activation
Keywords T cell activation butyrophilins Vγ9Vδ2 T cell receptor phosphoantigen germline-encoded region CDR3 molecular glue dual-ligand recognition innate and adaptive immunity Get full text access Log in, subscribe or purchase for full access. References 1. Rossjohn, J. ∙ Gras, S. ∙ Miles, J.J. ... T cell antigen receptor recognition of antigen-presenting molecules Annu. Rev. Immunol. 2015; 33:169-200 2. Vantourout, P. ∙ Hayday, A. Six-of-the-best: unique contributions of γδ T cells to immunology Nat. Rev.
Atmospheric Reactive Halogens Reshaped by the Clean Energy Policy and Agricultural Activity in a Rural Area of the North China Plain
Occurrence, Fate, and Transport of Contaminants in Indoor Air and AtmosphereJune 9, 2025 Xiaorui Chen Department of Civil and Environmental Engineering, The Hong Kong Polytechnic University, Hong Kong SAR 999077, China Yifan Jiang Department of Civil and Environmental Engineering, The Hong Kong Polytechnic University, Hong Kong SAR 999077, China Zheng Zong Department of Civil and Environmental Engineering, The Hong Kong Polytechnic University, Hong Kong SAR 999077, China Yanan Wang Department...
Atmospheric Reactive Halogens Reshaped by the Clean Energy Policy and Agricultural Activity in a Rural Area of the North China Plain
Occurrence, Fate, and Transport of Contaminants in Indoor Air and AtmosphereJune 9, 2025 Xiaorui Chen Department of Civil and Environmental Engineering, The Hong Kong Polytechnic University, Hong Kong SAR 999077, China Yifan Jiang Department of Civil and Environmental Engineering, The Hong Kong Polytechnic University, Hong Kong SAR 999077, China Zheng Zong Department of Civil and Environmental Engineering, The Hong Kong Polytechnic University, Hong Kong SAR 999077, China Yanan Wang Department...
One‐Step Symbiosis of Bimetallic Peroxides Nanoparticles to Induce Ferroptosis/Cuproptosis and Activate cGAS‐STING Pathway for Enhanced Tumor Immunotherapy
Conflict of Interest The authors declare no conflict of interest. Supporting Information Filename Description adma202500337-sup-0001-SuppMat.docx6.9 MB Supporting Information References 1a) , , , , , , Nature 2019, 574, 45; b) , Nat. Rev. Cancer 2019, 19, 587; c) , , , Nature 2011, 480, 480. 2a) , , Immunity 2013, 39, 1; b) , , , , , , Chem. Commun. 2021, 57, 12087. 3a) , , , , , , , , , , , Adv. Mater. 2019, 31, 1900499; b) , , , , , Adv. Drug Delivery Rev. 2022, 182, 114107; c) , , , , Nat. Rev.
Study on the Chromogenic Mechanism of Blue Kyanite from Coronel Murta, Minas Gerais, Brazil
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Rates and Patterns of Town Expansion in China’s 17 Shrinking Tourism-Type Counties
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Theoretical Investigation of Elastic, Electronic, and Thermodynamic Properties of Half-Heusler Semiconductors ZrNiPb and ZrPdPb Under Pressure
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Structural Characterization of Mycobacterium tuberculosis Encapsulin in Complex with Dye-Decolorizing Peroxide
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
The presence of broadly neutralizing anti-SARS-CoV-2 RBD antibodies elicited by primary series and booster dose of COVID-19 vaccine
Loading metrics Open Access Peer-reviewed Research Article ? This is an uncorrected proof. Citation: Chen X, Mohapatra A, Nguyen HTV, Schimanski L, Kit Tan T, Rijal P, et al. (2024) The presence of broadly neutralizing anti-SARS-CoV-2 RBD antibodies elicited by primary series and booster dose of COVID-19 vaccine. PLoS Pathog 20(6): e1012246. https://doi.org/10.1371/journal.ppat.1012246 Editor: Penny L.
Echinatin attenuates acute lung injury and inflammatory responses via TAK1-MAPK/NF-κB and Keap1-Nrf2-HO-1 signaling pathways in macrophages
Loading metrics Open Access Peer-reviewed Research Article Citation: Luo L, Wang H, Xiong J, Chen X, Shen X, Zhang H (2024) Echinatin attenuates acute lung injury and inflammatory responses via TAK1-MAPK/NF-κB and Keap1-Nrf2-HO-1 signaling pathways in macrophages. PLoS ONE 19(5): e0303556. https://doi.org/10.1371/journal.pone.0303556 Editor: Wei Hsum Yap, Taylor’s University, MALAYSIA Received: December 27, 2023; Accepted: April 27, 2024; Published: May 16, 2024 Copyright: © 2024 Luo et al.
Solid-State Nanopore Sensors with Enhanced Sensitivity through Nucleic Acid Amplification
Solid-state nanopores have wide applications in DNA sequencing, energy conversion and storage, seawater desalination, sensors, and reactors due to their high stability, controllable geometry, and a variety of pore-forming materials. Solid-state nanopore sensors can be used for qualitative and quantitative analyses of ions, small molecules, proteins, and nucleic acids.
Solid-State Nanopore Sensors with Enhanced Sensitivity through Nucleic Acid Amplification
Solid-state nanopores have wide applications in DNA sequencing, energy conversion and storage, seawater desalination, sensors, and reactors due to their high stability, controllable geometry, and a variety of pore-forming materials. Solid-state nanopore sensors can be used for qualitative and quantitative analyses of ions, small molecules, proteins, and nucleic acids.
Future reductions of China’s transport emissions impacted by changing driving behaviour - Nature Sustainability
Abstract This paper examines what individual drivers can contribute to reduce global vehicle emissions in their daily driving. Here we analyse vehicle emissions from the behavioural perspective with the aim of identifying ways in which drivers can reduce emissions by modifying their driving behaviour.
Structure of the heterotrimeric membrane protein complex FtsB-FtsL-FtsQ of the bacterial divisome - Nature Communications
Abstract The synthesis of the cell-wall peptidoglycan during bacterial cell division is mediated by a multiprotein machine, called the divisome. The essential membrane protein complex of FtsB, FtsL and FtsQ (FtsBLQ) is at the heart of the divisome assembly cascade in Escherichia coli. This complex regulates the transglycosylation and transpeptidation activities of the FtsW-FtsI complex and PBP1b via coordination with FtsN, the trigger for the onset of constriction.
Supramolecular Self-Assembly and Photo-Induced Transition of a Halogenated Azo-Benzene Molecule on Au(111) Surface
This is an early access version, the complete PDF, HTML, and XML versions will be available soon.
Author Correction: Cryo-EM structure of Helicobacter pylori urease with an inhibitor in the active site at 2.0 Å resolution - Nature Communications
Correction to: Nature Communications https://doi.org/10.1038/s41467-020-20485-6, published online 11 January 2021 The original version of this Article contained an error in the Acknowledgements section, which incorrectly omitted the following: ‘We thank Dr Eric Samuels for initial contributions to the urease purification protocol and activity assay’. This has been corrected in both the PDF and HTML versions of the Article.
High-Sensitivity Fluorescence Detection for lung cancer CYFRA21-1 DNA based on Accumulative Hybridization of Quantum Dots
High-Sensitivity Fluorescence Detection for lung cancer CYFRA21-1 DNA based on Accumulative Hybridization of Quantum Dots Sensitive detection of circulating tumor DNA (ctDNA) in vitro has attracted growing attention owing to its potential application in diagnostics of cancer.
Real-world effectiveness of COVID-19 vaccines: a literature review and meta-analysis
Highlights • The COVID-19 VE in real-world settings. • The COVID-19 VE for fully and partially vaccinated individuals. • The COVID-19 VE for health care workers, the elderly, and adults. • The effectiveness of different COVID-19 vaccine brands. Abstract Objectives To estimate the COVID-19 vaccine effectiveness (VE) against concerned outcomes in real-world settings. Methods We included studies reported the COVID-19 VE from August 6, 2020, to October 6, 2021.
Cryo-EM structure of Helicobacter pylori urease with an inhibitor in the active site at 2.0 Å resolution
Abstract Infection of the human stomach by Helicobacter pylori remains a worldwide problem and greatly contributes to peptic ulcer disease and gastric cancer. Without active intervention approximately 50% of the world population will continue to be infected with this gastric pathogen. Current eradication, called triple therapy, entails a proton-pump inhibitor and two broadband antibiotics, however resistance to either clarithromycin or metronidazole is greater than 25% and rising.
Upconversion nanoparticles coated with molecularly imprinted polymers for specific sensing
Upconversion nanoparticles coated with molecularly imprinted polymers for specific sensing Ling Yang,ab Xiaorui Chen,a Ping'an Ma,ab Dayong Jin, cd Jiajia Zhou, *d Hao He,*c Ziyong Cheng*ab and Jun Lin *ab Author affiliations * Corresponding authors a State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, P. R.
A carbohydrate-binding protein from the edible Lablab beans effectively blocks the infections of influenza viruses and SARS-CoV-2
Highlights • FRIL is a plant lectin with potent anti-influenza and anti-SARS-CoV-2 activity. • FRIL preferentially binds to complex type N-glycans on viral glycoproteins. • FRIL inhibits influenza virus entry by sequestering virions in late endosomes. • Intranasal administration of FRIL protects against lethal H1N1 challenge in mice. Summary The influenza virus hemagglutinin (HA) and coronavirus spike (S) protein mediate virus entry.
Field Determination of Nitrate Formation Pathway in Winter Beijing
Particulate nitrate (pNO3–) has often been found to be the major component of fine particles in urban air-sheds in China, the United States, and Europe during winter haze episodes in recent years. However, there is a lack of knowledge regarding the experimentally determined contribution of different chemical pathways to the formation of pNO3–.
Comparison of Immunogenicity and Protection of Two Pneumococcal Protein Vaccines Based on PsaA and PspA
Streptococcus pneumoniae is a major cause of invasive pneumococcal disease, septicemia, and meningitis that can result in high morbidity rates in children under 5 years old. The current polysaccharide-based vaccines can provide type-specific immunity, but a broad-spectrum vaccine would provide greater coverage. Therefore, developing pneumococcal-protein-based vaccines that can extend to more serum types is highly important.
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