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Articles by Xin Chang
Language adaptation of international immigrants: connotation and dimensions
International immigrants’ adaptation to language life and satisfaction of their linguistic demands are precondition for successful integration into the host country’s society. However, current theories and studies on immigrants’ language adaptation are insufficient to support further research on the language adaptation of international immigrants in the host country.
Research and application of directional fracturing roof cutting for lateral thick and hard roofs in shallow-buried large-section roadways
Abstract Aimed at the severe strata behavior hazards caused by the occurrence of lateral thick and hard roofs in shallow-buried large-section roadways, a directional fracturing and roof cutting technology for lateral thick and hard roof zones in shallow-buried large-section coal mine roadways is proposed. Key technologies of directional fracturing for such roof regions are investigated using a comprehensive approach including theoretical analysis, numerical simulation, and field testing.
Compartment Fire Dynamics and Surrogate-Assisted Optimization in Confined Electrical Infrastructure
ABSTRACT This paper presents a surrogate-assisted optimization framework for performance-based fire protection design of confined electrical infrastructure, demonstrated on 65 Fire Dynamics Simulator (FDS) simulations of a distribution room and a cable trench. A cell-by-cell geometry validator revealed that FDS silently discards obstructions, vents, and fire surfaces falling outside the mesh or on solid cells; all 65 inputs were corrected.
Neoadjuvant disitamab vedotin (RC-48) plus a PD-1 inhibitor in muscle-invasive bladder cancer: a multicenter real-world study with stratification by HER2 expression and tertiary lymphoid structures
Abstract Objective: To assess the efficacy and safety of neoadjuvant RC-48 combined with a PD-1 inhibitor in patients with muscle-invasive bladder cancer (MIBC), and to investigate the stratification utility of HER2 expression and tumor-associated tertiary lymphoid structures (TLS) as predictive variables for treatment response and clinical prognosis.
Algorithmic performance appraisal intensity in hospitals: implications for professional autonomy and innovative work behavior
Abstract Introduction: Hospitals increasingly use algorithmic systems to monitor, compare, score, and appraise employees. Although such systems may improve consistency and efficiency, intensive use may constrain medical professionals’ autonomy and their innovative behavior. This study examined the relationships among algorithmic performance appraisal intensity, perceived professional autonomy, and innovative work behavior, and tested whether algorithmic transparency moderates these relationships.
Citrullination of cathepsin H promotes NETs formation and exacerbates IBD via PI3K-Akt pathway
Keywords inflammatory bowel disease peptidyl arginine deiminase 4 cathepsin H citrullination phosphatidylinositol 3-kinases/protein kinase B Research topic(s) CP: immunology Introduction Inflammatory bowel disease (IBD), which includes Crohn disease (CD) and ulcerative colitis (UC), is a chronic, relapsing inflammatory disorder of the gastrointestinal tract.1 With the advancement of the global economy, the incidence of IBD has increased substantially over the past 30 years.2 Especially, in...
Single cell and bulk transcriptomics reveal metabolic reprogramming biomarker signatures during extracorporeal membrane oxygenation for cardiogenic shock
Abstract Cardiogenic shock (CS) patients receiving extracorporeal membrane oxygenation (ECMO) exhibit profound immune and metabolic disturbances, which may influence early clinical outcomes. However, the transcriptomic features linking metabolic reprogramming, immune-cell alterations, and early outcomes after ECMO initiation remain incompletely understood.
Multiphase nanocomposite prelithiation agents for service life lithium replenishment in Si-based Li-ion batteries
Abstract INTRODUCTION RESULTS DISCUSSION MATERIALS AND METHODS Acknowledgments Supplementary Materials REFERENCES Information & Authors Metrics & Citations View Options References Figures Tables Media Share Abstract High–energy density lithium-ion batteries (LIBs) using Si-based anodes are expected to dominate the lithium-ion power battery market in the near future. However, the Si anode suffers from continuous capacity degradation during initial and subsequent cycles.
Anisodine hydrobromide targets matk and prevents delayed rtPA thrombolysis-induced vasogenic cerebral edema in ischemic stroke
Abstract Vasogenic cerebral edema is a severe complication of delayed thrombolysis for ischemic stroke, for which no pharmacological treatment exists. Anisodine hydrobromide (Ani), an alkaloid used clinically in China for vascular disorders, is investigated for its potential to mitigate this condition. Here we show that Ani treatment improves survival and neurological function in a mouse model of delayed rtPA-induced cerebral edema by preserving the integrity of the blood-brain barrier.
Multiple Genetic Shifts at the Crossroads of the Eastern Steppe and Loess Plateau Over 4,000 Years
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Abstract Ningxia, located at a key crossroads between the Eurasian Steppe and East Asia, was an important corridor for cultural exchange and human migration, yet its genetic history has remained poorly understood. In this study, we sequenced 89 individuals from 23 archeological sites in Ningxia, dating from 4245 to 301 BP. Our findings show that late Neolithic inhabitants of Ningxia possessed ancestral components from the Yellow River, Ancient Northeast Asia, and the Tibetan Plateau.
By Xin Chang, Yu Xu, Hongying Zhang, Qiang Ma, Hailiang Meng, Tingting Bai, Xiaomin Yang, Kun Wang, Jianxue Xiong, Panxin Du, Tianyou Bai, Hao Ma, Xiaoying Ren, Bangyan Wang, Baoshuai Zhang, Hetong Wen, Ke Wang, Kongyang Zhu, Rui Wang, Jiajing Zheng, Feng Luo, Li Jin, Chuan-Chao Wang, Chenshuang Sun, Huangzhen Huang, Shaoqin Wen
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Nature
Verified
Efficacy Evaluation of Urethral Dragging-and-Adhesion Anastomosis in Ileal Orthotopic Neobladder Reconstruction Following Laparoscopic Radical Cystectomy: a dual-center retrospective study
ORIGINAL RESEARCH article Volume 13 - 2026 | doi: 10.3389/fsurg.2026.1874547 Reviewed by ORIGINAL RESEARCH article XC Xin Chang Zou 2 HC HAICHAO CHAO 2 TZ Tao Zeng 2 1. Nanchang University, Nanchang, China 2. Second Affiliated Hospital of Nanchang University, Nanchang, China 3.
Population history and subsistence of farming communities in an agro-pastoral transition zone of northern China: ancient DNA and isotopic evidence from the Erdaojingzi site
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Abstract This study investigates the population history and subsistence of farming communities at the Erdaojingzi site (ca. 3700–3330 cal. BP), a well-preserved Bronze Age settlement located in the agro-pastoral transition zone of the West Liao River Basin in northern China.
By Xiaohong Lv Verified, Yao Yu, Lin Ban, Panxin Du, Jianxue Xiong, Xin Chang, Baoshuai Zhang, Bangyan Wang, Yiran Xu, Chunxue Wang, Shaoqing Wen, Jianen Cao
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Nature
Verified
Disitamab Vedotin (RC48) Combined with PD-1 Inhibitors in Locally Advanced or Metastatic Urothelial Carcinoma: Clinical Outcomes and Prognostic Factors from a Multicenter Real-World Study
ORIGINAL RESEARCH article Volume 17 - 2026 | doi: 10.3389/fimmu.2026.1815591 Reviewed by ORIGINAL RESEARCH article XC Xin Chang Zou 1 TZ Tao Zeng 6 1. Second Affiliated Hospital of Nanchang University, Nanchang, China 2. Jiangxi Provincial People's Hospital, Nanchang, China 3. Jiangxi Cancer Hospital, Nanchang, China 4. The First Affiliated Hospital of Nanchang University, Nanchang, China 5. Affiliated Jiujiang Hospital of Nanchang University, Jiujiang, China 6.
How Do Misvalued Firms Deploy Internal Cash Flow?
Conflicts of Interest The authors declare no conflicts of interest. Data Availability Statement Research data are not shared. Supporting Information Filename Description jbfa70042-sup-0001-OnlineAppendix.docx120.5 KB Supporting: jbfa70042-sup-0001-OnlineAppendix.docx References , and . 2018. “Investor Overconfidence, Firm Valuation, and Corporate Decisions.” Management Science 64, no. 11: 5349–5369. https://doi.org/10.1287/mnsc.2017.2806. , and . 2010.
Frontiers | Case Report: Tail-of-the-curve advantage from immune checkpoint inhibitor-anti-VEGF combination therapy: extended survival in a patient with metastatic lung adenocarcinoma
CASE REPORT article Volume 12 - 2025 | https://doi.org/10.3389/fmed.2025.1714486 This article is part of the Research TopicCase Reports in Pulmonary Medicine 2025View all 27 articles Lung cancer remains one of the most burdensome malignancies worldwide and is associated with a dismal prognosis (1). Global population-based survival analyses across 185 countries have demonstrated that lung cancer continues to rank first in both incidence and cancer-related mortality among men (2).
Molecular Engineering of Organic Prelithiation Agents via Frontier Orbital Regulation
Cite Jump to ExpandCollapse ArticleOctober 23, 2025 Molecular Engineering of Organic Prelithiation Agents via Frontier Orbital Regulation Click to copy article linkArticle link copied! Chen Li Chen Li CAS Key Laboratory of Molecular Nanostructure and Nanotechnology, CAS research/Education Center for Excel-Lence in Molecular Sciences, Beijing National Laboratory for Molecular Sciences (BNLMS), Institute of Chemistry, Chinese Academy of Sciences (CAS), Beijing 100190, P. R.
From Static Scaffolds to Dynamic Highways: Spatially Ordered Nanotube Tracks Improve Pathway Control and Accelerate DNA Walker Kinetics for Enhanced MicroRNA Detection
Cite Jump to ExpandCollapse ArticleOctober 22, 2025 From Static Scaffolds to Dynamic Highways: Spatially Ordered Nanotube Tracks Improve Pathway Control and Accelerate DNA Walker Kinetics for Enhanced MicroRNA Detection Click to copy article linkArticle link copied! Yongli Wu Yongli Wu College of Chemistry, Jilin Province Research Center for Engineering and Technology of Spectral Analytical Instruments, Jilin University, Qianjin Street 2699, Changchun 130012, China Xin Chang Xin Chang...
The genomic history of East Asian Middle Neolithic millet- and rice-agricultural populations
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Keywords ancient DNA Middle Neolithic Yellow and Yangtze river proto-Austronesian origin adaptive EPAS1 haplotype Introduction The advent of agriculture represented a crucial transition from foraging to farming, initiating profound changes in lifestyle, demographics, health, genetic adaptation, and culture.1,2,3,4,5,6,7 This agricultural revolution emerged independently in various regions, including West Asia, East Asia, and the Americas, before gradually spreading to adjacent...
By Jianxue Xiong, Yu Xu, Guoke Chen, Liping Yang, Yawei Zhou, Yiling Pan Verified, Zhiyou Wang, Baoshuai Zhang, Guanghui Dong, Xiaomin Yang, Liang Chen, Yangyang Wu, Bangyan Wang, Kongyang Zhu, Panxin Du, Xiaolong Li, Xiaolin Ma, Wanfa Gu, Yu Ye, Qian Wu, Xin Chang, Jingze Tan, Lei Gao, Dong Ge, Bicheng Li, Yishi Yang, Weiwei Feng, Yini Yang, Pengfei Sheng, Hailiang Meng, Rui Wang, Jiajing Zheng, Xin Jia, Li Jin, Chuan-Chao Wang, Shaoqing Wen, Jiujiang Bai, Jingrong Pei, Ningwu Kang, Hetong Wen, Tianyou Bai
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Cell Press
Verified
Element‐Engineered Lithium Borate for High‐Efficiency Prelithiation in Silicon‐Based Lithium‐Ion Batteries
Conflict of Interest The authors declare no conflict of interest. Supporting Information Filename Description adma70055-sup-0001-SuppMat.docx6.6 MB Supporting Information References 1a) , , , , , J. Mater. Chem. A 2019, 7, 2942; b) , , , , , J. Electrochem. 2023, 29, 2217009. 2, , , , , Energy Storage Mater. 2019, 23, 144. 3, , Battery500 Consortium: Development of High Capacity Cathodes and Robust Solid Electrolytes, U. S.
Sortilin‐Mediated Rapid, Precise and Sustained Degradation of Membrane Proteins via mRNA‐Encoded Lysosome‐Targeting Chimera
1 Introduction MPs constitute ≈23% of the human proteome and account for over 60% of therapeutic targets, underscoring their crucial roles in diseases such as autoimmune disorders, neurodegenerative conditions and cancers.[1] For instance, activation of the epidermal growth factor receptor (EGFR) pathway promotes cell proliferation and metastasis in many cancers,[2] while overexpression of programmed death-ligand 1 (PD-L1) enables cancer cells to evade immune surveillance.[3] Advances in...
Foreign investors’ reactions to China’s ‘Double Reduction’ policy: evidence from the A-H market divergence
ABSTRACT Utilizing segmented dual class shares of Chinese firms (A-shares traded in mainland China and H-shares in Hong Kong), we document significant negative market response and a decrease in liquidity from foreign investors to the ‘Double Reduction’ policy, whose impact extends beyond the education sector and affects other markets.
Meyer-Schuster rearrangement/allylic alkenylation of propynolaldehydes with olefins to skipped 1,4-dienes
Meyer-Schuster rearrangement/allylic alkenylation of propynolaldehydes with olefins to skipped 1,4-dienes A highly efficient method for the straightforward synthesis of skipped 1,4-dienes is presented via p-TsOH•H2O-catalyzed intramolecular intercepted Meyer-Schuster rearrangement/allylic alkenylation of propynolaldehydes with olefins in a one-pot manner.
Role and Regulation of Surface Oxygen Vacancy in Vanadium-Based Oxides for Chemical Looping Oxidative Dehydrogenation of Propane
Role and Regulation of Surface Oxygen Vacancy in Vanadium-Based Oxides for Chemical Looping Oxidative Dehydrogenation of Propane Redox catalysts play a critical role in chemical looping oxidative propane dehydrogenation (CL-ODH). However, challenges persist in modulating lattice oxygen in metal oxides and maintaining surface oxygen coverage to prolong the oxidative dehydrogenation stage.
Phosphinylation/Cyclization of Propynolaldehydes to Isobenzo- furanylic Phosphine Oxides Displaying AIE Properties
Phosphinylation/Cyclization of Propynolaldehydes to Isobenzo- furanylic Phosphine Oxides Displaying AIE Properties Investigating organic reactions to synthesize novel molecules that exhibit aggregation-induced emission (AIE) characteristics is becoming a research hotspot. Herein, we develop a one-pot phosphinylation/cyclization reaction between propynolaldehydes and diarylphosphine oxides to generate isobenzofuran-substituted phosphine oxides (IBFPOs) displaying AIE properties.
ESFCU‐Net: A Lightweight Hybrid Architecture Incorporating Self‐Attention and Edge Enhancement Mechanisms for Enhanced Polyp Image Segmentation
Conflicts of Interest The authors declare no conflicts of interest. References 1, , , et al., “Computer-Aided Classification of Gastrointestinal Lesions in Regular Colonoscopy,” IEEE Transactions on Medical Imaging 35, no. 9 (2016): 2051–2063, https://doi.org/10.1109/TMI.2016.2547947. 2 and , “Gastritis, Gastric Polyps and Gastric Cancer,” International Journal of Molecular Sciences 22, no. 12 (2021): 6548, https://doi.org/10.3390/ijms22126548.
Size Engineering of Ti3C2Tx Nanosheets for Enhanced Supercapacitance Performance
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Based on network pharmacology and experiments to prove the effective i
Back to Journals » Journal of Inflammation Research » Volume 18 Authors Wang X, Zhang Y, Chang X , Wen X, Tian F, Yu H, Li Y Received 15 November 2024 Accepted for publication 8 May 2025 Published 21 May 2025 Volume 2025:18 Pages 6505—6527 DOI https://doi.org/10.2147/JIR.S506716 Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 2 Editor who approved publication: Professor Ning Quan Xuan Wang,1,* Yunheng Zhang,1,* Xin Chang,1 Xiaodong Wen,1 Feng...
A low‐cost trans‐scale model for the collaborative analysis of the manufacturing and in‐service process of unidirectional CFRP composites
REFERENCES 1. Distortions of composite aerospace frames due to processing, thermal loads and trimming operations and an assessment from an assembly perspective. Compos Struct. 2019; 220: 338-346. 2, , . Recent progresses of fabrication and characterization of fibers-reinforced composites: a review. Compos Commun. 2019; 14: 34-42. 3, , , . A review on process-induced distortions of carbon fiber reinforced thermosets for large-scale production. Prod Eng. 2017; 11(6): 665-675. 4, .
Discontinuous Distribution of Test Statistics Around Significance Thresholds in Empirical Accounting Studies
Accepted by Luzi Hail.
Can Short-Term Online-Monitoring Improve the Current WFD Water Quality Assessment Regime? Systematic Resampling of High-Resolution Data from Four Saxon Catchments
The European Union Water Framework Directive (2000/60/EC; WFD) aims to achieve a good ecological and chemical status of all bodies of surface water by 2027. The development of integrated guidance on surface water chemical monitoring (e.g., WFD Guidance Document No. 7/19) has been transferred into national German law (Ordinance for the Protection of Surface Waters, OGewV).
CEO Locality and Corporate Social Responsibility
Supporting Information References and (2019). ‘Critique on the ‘manager effects’ research and implications for management accounting research’, Journal of Management Accounting Research, 31, pp. 3–40. , and (2019). ‘Corporate social responsibility and firm risk: theory and empirical evidence’, Management Science, 65, pp. 4451–4469. https://doi.org/10.1287/mnsc.2018.3043 , , and (2009). ‘Winter heating or clean air? Unintended impacts of China's Huai river policy’, American Economic Review, 99, pp.
Study on the influence of vertical stress difference coefficient on fracture characteristics of shale under high stress
1 INTRODUCTION With the growth of the global population and the development of the economy, the demand for energy is increasing. Deep shale contains abundant gas and oil resources, thus becoming an important potential source to meet energy demand. With the gradual decline of traditional oil and gas resources, the development of unconventional oil and gas has become an important means to fill the energy gap. As a part of it, deep shale has attracted more research attention.
Approaching Sustainable Lithium‐Ion Batteries through Voltage‐Responsive Smart Prelithiation Separator with Surface‐Engineered Sacrificial Lithium Agents
Conflict of interests The authors declare no conflict of interest. Supporting Information As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors.
Copper/Ruthenium Relay Catalysis Enables 1,6-Double Chiral Inductions with Stereodivergence
Copper/Ruthenium Relay Catalysis Enables 1,6-Double Chiral Inductions with Stereodivergence Dual catalysis strategy is an efficient and powerful tool to fulfill the stereodivergent synthesis of all stereoisomeric products from the same set of the starting materials, and great attentions have been paid on the construction of chiral compounds bearing two contiguous stereocenters.
Investigation of the Impact Load Characteristics during Water Entry of Airdropped Underwater Gliders
1. Introduction Underwater gliders, characterized by their low energy consumption and long endurance capabilities, have found widespread application in ocean observation [1]. Launching underwater gliders to the target sea area via aircraft, as opposed to deployment by a mother ship, can significantly broaden the application scope of gliders.
Research on a Real-Time Prediction Method of Hull Girder Loads Based on Different Recurrent Neural Network Models
1. Introduction The hull girder loads are an important factor affecting the overall structural safety of ships, which is a key focus in the design and use of ship structures [1,2]. Real-time prediction of hull girder load data will be of great help to the captain’s navigation decision-making, especially in high-sea conditions when the hull girder loads are large and there is a high risk of failure in the ship’s structure.
Visible-Light-Enabled Stereoselective Synthesis of Functionalized Cyclohexylamine Derivatives via [4 + 2] Cycloadditions
Visible-Light-Enabled Stereoselective Synthesis of Functionalized Cyclohexylamine Derivatives via [4 + 2] Cycloadditions An unprecedented intermolecular [4 + 2] cycloaddition of benzocyclobutylamines with α-substituted vinylketones enabled by photoredox catalysis has been developed. The current method enables a facile access to highly functionalized cyclohexylamine derivatives that were otherwise inaccessible in moderate to good yields with excellent diastereoselectivities.
Water | Free Full-Text | Can Short-Term Online-Monitoring Improve the Current WFD Water Quality Assessment Regime? Systematic Resampling of High-Resolution Data from Four Saxon Catchments
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
The Effect of Convective/Advective Precipitation Partitions on the Precipitation Isotopes in the Monsoon Regions of China: A Case Study of Changsha
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Can Short-Term Online-Monitoring Improve the Current WFD Water Quality Assessment Regime? Systematic Resampling of High Resolution Data From Four Saxon Catchments
Preprint Article Version 1 This version is not peer-reviewed Version 1 : Received: 21 February 2024 / Approved: 22 February 2024 / Online: 22 February 2024 (03:36:17 CET) Benisch, J.; Helm, B.; Chang, X.; Krebs, P. Can Short-Term Online-Monitoring Improve the Current WFD Water Quality Assessment Regime? Systematic Resampling of High Resolution Data From Four Saxon Catchments. Preprints 2024, 2024021266. https://doi.org/10.20944/preprints202402.1266.v1 Benisch, J.; Helm, B.; Chang, X.; Krebs, P.
Boosting Sodium Compensation Efficiency via a CNT/MnO2 Catalyst toward High-Performance Na-Ion Batteries
RETURN TO ARTICLES ASAPPREVEnergy, Environmenta...Energy, Environmental, and Catalysis ApplicationsNEXT Wei-Huan He CAS Key Laboratory of Molecular Nanostructure and Nanotechnology, Beijing National Laboratory for Molecular Sciences (BNLMS), Institute of Chemistry, Chinese Academy of Sciences (CAS), Beijing 100190, P. R. China School of Chemical Sciences, University of Chinese Academy of Sciences (UCAS), Beijing 100049, P. R.
A rare cause of recurrent acute pancreatitis: ectopic opening of the pancreatic duct (with videos)
A 22-year-old woman presented with recurrent upper abdominal pain for 2 years, with 6 episodes of acute pancreatitis (AP). She received a diagnosis of recurrent AP and was admitted for further evaluation. To read this article in full you will need to make a payment Subscribe to Gastrointestinal Endoscopy Article info Drs Song, Chang, Gu, Wu, Yan, and Wang contributed equally to this work. DOI: https://doi.org/10.1016/j.gie.2024.01.018 Access this article on ScienceDirect Related Articles
Curcumin alleviates OA through the P38MAPK pathway
Back to Journals » Journal of Inflammation Research » Volume 17 Authors Wang X, Yu H, Zhang Y, Chang X , Liu C, Wen X, Tian F, Li Y Received 16 January 2024 Accepted for publication 10 July 2024 Published 26 July 2024 Volume 2024:17 Pages 5039—5056 DOI https://doi.org/10.2147/JIR.S459867 Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 2 Editor who approved publication: Dr Adam D Bachstetter Xuan Wang,1,* Hanjie Yu,2,* Yunheng Zhang,3,* Xin...
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