Xin Lin
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Articles by Xin Lin
A synaptic mitochondrion–ribbon–vesicle complex organizes photoreceptor neurotransmission
Abstract Photoreceptor synapses rely on mitochondria, synaptic ribbons, and vesicles, yet how these elements integrate into functional units remains unclear. Here we show, using focused ion beam-scanning electron microscopy (FIB-SEM) and electrophysiology, that they form synaptic mitochondrion–ribbon–vesicle complexes (sMRVcs) with fundamentally different architectures in rods and cones.
Integrative plasma proteomic and Mendelian randomization analyses prioritize an SH2B3-centered immunogenetic signal in coronary heart disease
Abstract Background: Coronary atherosclerosis is shaped by immune, vascular, and metabolic interactions, but genetic links between circulating protein networks and immune-regulatory mechanisms remain incompletely resolved.
Code2Video-Compass: A Comprehensive Benchmark for General-Purpose Code-Based Video Generation across T2V, I2V, and V2V
Abstract Code2Video-Compass is a benchmark evaluating multimodal language models on code-based video generation across text, image, and video inputs, revealing significant challenges in complex dynamic and state-dependent tasks. Code-based video generation offers fine-grained control, targeted editing, and component reuse compared with direct video generation.
Soluble urokinase plasminogen activator receptor across the kidney–cardiometabolic continuum: a systematic review
Abstract Background: Soluble urokinase plasminogen activator receptor (suPAR), a circulating marker of innate immune activation, has been proposed as a risk biomarker in chronic kidney disease (CKD) and related cardiometabolic conditions, but its clinical utility remains uncertain.
Risk of bias and applicability of prediction models for outcomes of peritoneal dialysis-related peritonitis: a PROBAST systematic review
Abstract Background: Peritoneal dialysis (PD)-related peritonitis frequently causes hospitalization, catheter loss, hemodialysis transfer, and death. Existing reviews have focused on peritonitis incidence rather than post-diagnosis outcomes. We systematically reviewed prediction models for post-peritonitis outcomes and assessed their risk of bias and applicability using PROBAST.
CRISPRa screen unveils noncanonical NF-κB to boost the antitumor activity of TCR-based CAR-T cells
Abstract Engineering autologous T cells for adoptive therapies has revolutionized cancer treatment, yet limited persistence remains a major barrier to robust clinical responses and durable disease control.
Abrupt pH changes overestimate the responses of Chaetoceros muelleri to ocean acidification
Abstract Ocean acidification, characterized by a gradual seawater pH decline, influences marine primary producers such as diatoms, which contribute substantially to oceanic carbon fixation. Experimental studies aiming to project climate change impacts often simulate acidification via abrupt pH shifts, potentially misrepresenting ecological and evolutionary responses.
SynthGait-19K: A Physically Grounded Synthetic Video Dataset for Gait Parameter Estimation
Get this paper in your agent: hf papers read 2609.08108 Don't have the latest CLI? curl -LsSf https://hf.co/cli/install.sh | bash Models citing this paper 0 No model linking this paper Cite arxiv.org/abs/2609.08108 in a model README.md to link it from this page. Datasets citing this paper 0 No dataset linking this paper Cite arxiv.org/abs/2609.08108 in a dataset README.md to link it from this page.
Closed-loop in situ isolation of deep-sea extremophiles through sensor-driven microenvironment preservation
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Abstract Deep sea microorganisms remain largely inaccessible because existing sampling and cultivation methods fail to preserve native high-pressure microenvironments from seafloor to laboratory. Here we show a closed-loop cyber physical platform that maintains in situ deep-sea conditions through real-time sensing, digital twin control and robotic high-pressure manipulation to enable targeted isolation of extremophiles.
By Jing-Chun Feng, Guang Yang, Canrong Li, Chunlei Chen, Rui Lu, Yuhang Zhang, Xuanyu Tao, Zhifeng Yang, Cun Li, Yue Zhu, Renzeng Shi, Chaoqi Li, Mingxin Wu, Qian Zhang, Bingxu Hu, Jinhua Li, Kelei Zhu, Minghui Shi, Li Tang, Hongyi Liu, Junjie Chen, Yihan Shao, Wentao Wang, Nan Zhao, Weicong Liang, Xin Lin, Xiaokang Wang, Qixuan Wu, Zhen Zhang, Dapeng Zou, Zhengguang Liu, Yi Wang, Si Zhang, Mengzhuo Zhu, Weiyu Yuan, Liangyun Qin, Jianzhen Liang, Jingnan Tian, Junrong Zhai, Nishi Yu
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Nature
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Effects of Auricular Acupressure Combined With Heat-Sensitive Moxibustion on Gastrointestinal Hormone Levels and Recovery of Gastrointestinal Function After Laparoscopic Colorectal Cancer Surgery
1 Introduction Laparoscopic radical resection has become the preferred surgical approach for colorectal cancer because it is minimally invasive and facilitates faster recovery. Nevertheless, postoperative complications—such as infection and gastrointestinal (GI) dysmotility—remain common. Surgical trauma and the ensuing inflammatory response can increase the risk of infection, disturb internal homeostasis, and hinder convalescence [1, 2].
Computer Science > Computation and Language
arXivLabs is a framework that allows collaborators to develop and share new arXiv features directly on our website. Both individuals and organizations that work with arXivLabs have embraced and accepted our values of openness, community, excellence, and user data privacy. arXiv is committed to these values and only works with partners that adhere to them. Have an idea for a project that will add value for arXiv's community? Learn more about arXivLabs.
Integrative metabolic and inflammatory phenotyping identifies cancer cachexia independent of weight history
Abstract Cancer cachexia (CCx) is a complex, multifactorial syndrome associated with poor outcomes, yet its clinical identification is often hindered by unreliable recall of historical body weight. We developed an interpretable machine learning (ML) framework to detect CCx by integrating routinely collected metabolic and inflammatory hematological features from the nationwide multicenter INSCOC cohort in China (N = 16,858).
Calibrating Mathematics Vocabulary Self-Efficacy: Domain-Specific Accuracy by Mathematics-Difficulty Risk Status
Abstract References Supplemental Material Get access More Cite Share options Information, rights and permissions Metrics and citations Abstract Knowledge of mathematics vocabulary is important for conceptual understanding, yet little is known about how students’ vocabulary self-efficacy corresponds to their performance or how accurately they judge their competence.
Associations between social media-based digital contact with family and friends on loneliness and well-being outcomes in middle-aged and older adults: a mediation analysis
Abstract Social connections are essential for well-being, particularly in middle-aged and older adults, but maintaining them becomes challenging due to shrinking social networks and physical limitations that hinder participation in social events. Social media offers a potential avenue for increasing social interaction and online social support, thereby reducing loneliness and enhancing well-being.
Nutrient starvation and phosphonate utilization coordinate buoyancy and high-light tolerance in Trichodesmium
Abstract The formation of surface blooms by the diazotrophic cyanobacterium Trichodesmium contributes extensively to carbon and nitrogen cycling. Yet the physiological drivers governing its vertical ascent and subsequent tolerance to high surface irradiance remain obscure. By measuring sinking and floating velocities, analyzing transcriptome responses, and tracking the subcellular distribution of gas vesicles, we show that nutrient starvation is the primary trigger for vertical ascent.
Oral GSDMD-N mRNA Nanoparticle-Induced Pyroptosis for the Treatment of Colorectal Cancer
Mingming Song, Li Wang, Xin Lin, Yujie Shi and Yurong Ou contributed equally to this work. Conflicts of Interest The authors declare no conflict of interest. Data Availability Statement The data that support the findings of this study are available from the corresponding author upon reasonable request. Supporting Information Filename Description smll74889-sup-0001-SuppMat.docx6.8 MB Supporting File: smll74889-sup-0001-SuppMat.docx.
Complement-targeted therapies for C3 glomerulopathy and atypical hemolytic uremic syndrome: a time-limited rapid systematic review with narrative synthesis
Abstract C3 glomerulopathy (C3G) and atypical hemolytic uremic syndrome (aHUS) are rare complement-mediated kidney diseases with differing injury sites and therapeutic targets. We conducted a time-limited rapid systematic review to synthesize clinical evidence on complement-targeted therapies.
SUMOylation activates ECHS1 for adaptive catabolism in lung cancer
Abstract Cellular metabolism dynamically adapts to nutrient fluctuations, yet the regulatory mechanisms underlying this plasticity remain incompletely understood. In particular, the adaptive activation mechanism of enoyl-CoA hydratase short-chain 1 (ECHS1), a key mitochondrial enzyme for fatty acid and amino acid catabolism, is poorly characterized.
Overcoming the Limitation of Low Electrical Conductivity of LiF-Rich SEI Toward Fast-Charging and High-Stability Silicon Anodes
, , , et al. “Overcoming the Limitation of Low Electrical Conductivity of LiF-Rich SEI Toward Fast-Charging and High-Stability Silicon Anodes.” Advanced Functional Materials (2026): e76829. https://doi.org/10.1002/adfm.76829 Conflicts of Interest The authors declare no conflicts of interest. Data Availability Statement The data that supports the findings of this study are available in the supplementary material of this article.
Mathematics Writing Across Tasks and Learners: Informative and Creative Writing of Chinese Students With Mathematics and Reading Difficulties
Abstract References Supplemental Material Get access More Cite Share options Information, rights and permissions Metrics and citations Abstract Mathematics writing is increasingly recognized as an important component of mathematical competence. However, research on mathematics writing remains limited, with most studies focusing on informative writing and its relation to mathematical knowledge.
Arquitectura y Seguridad en la Nube: El próximo nivel del desarrollador
Cuando una aplicación web funciona en local, parece que ya esta casi terminada. Pero en realidad todavía queda una parte muy importante: decidir donde va a vivir, como se va a proteger y que pasara si de repente la usan muchas personas a la vez. En este articulo voy a explicar, desde el punto de vista de un desarrollador Full-Stack, como llevar una aplicación web al entorno cloud de forma segura.
Structural Recovery of Overlooked Shrublands Drives Asymmetric Restoration in Dryland Ecosystems
1 Introduction Drylands, covering nearly 40% of Earth's land surface, are fundamental to global biogeochemical cycles and human well-being (Poulter et al., 2014; Reynolds et al., 2007). These ecosystems are shaped by scarce and variable water resources, strong climatic seasonality, and low soil fertility (D’Odorico et al., 2006; Kéfi et al., 2024; Maestre et al., 2016).
Hashimoto’s thyroiditis both promotes and protects against papillary thyroid cancer
Abstract The growing body of evidence suggests a complicated association between papillary thyroid cancer (PTC) and Hashimoto’s thyroiditis (HT). Although HT is a major risk factor for PTC development, it is also associated with improved patient outcomes. However, the molecular mechanisms between these two diseases remain unclear. This narrative review summarizes clinical evidence that connects HT with PTC and examines how these two conditions interact.
Dual epitope anti-LILRB4 synthetic T-cell receptor and antigen receptor (STAR)-T-cell therapy for relapsed/refractory acute myeloid leukemia
Abstract Acute myeloid leukemia (AML) is a rapidly progressive malignancy with poor prognosis. To date, chimeric antigen receptor (CAR) T-cell therapy in AML has been limited by the lack of antigens with high specificity for AML cells. Here, we developed a synthetic T-cell receptor and antigen receptor-T (STAR-T) cell therapy targeting LILRB4, an immunosuppressive receptor highly expressed on monocytic AML blasts but not on hematopoietic stem cells.
她们第一次走进德国法庭：中国留学生迷奸案庭审现场
Xin Lin 2026年5月21日2026年5月21日 一起涉及中国留学生的性侵案件日前在柏林开庭，吸引大量年轻女性前来旁听。检方称，案件部分情节涉及一个名为“德国老司机驾校”的Telegram群组。群组成员长期以“开车”、“加油”等隐语，交流如何对女性下药并实施性侵，并传播相关影像。 https://p.dw.com/p/5E5Im 前来旁听庭审的几乎全是年轻的中国女性 （德国之声中文网）在柏林刑事法院一楼一扇不起眼的白色小门外，前来旁听的人沿着狭窄的旋转楼梯一路排到三楼。 队伍里几乎全是年轻的中国女性。不少人提前一个多小时便已到场，但由于旁听席仅能容纳30人，最后仍有不少人未能进入法庭。 5月18日，柏林地方法院公开审理中国籍嫌疑人Zhiting S.。德国检方指控，他曾在一个Telegram群组中利用医学知识，为他人提供用于性侵的药物建议。检方还指控，他涉嫌于2019年至2021年间在北京多次性侵同一名女性，并在作案时拍摄视频。此外，他还被指持有儿童色情影像。 Zhiting S.案于2026年3月19日开审，目前预计将持续至6月。 骇人听闻的中国男留学生跨国迷奸案...
Xi recebe Putin em Pequim seis dias após visita de Trump
Xin Lin 20/05/202620 de maio de 2026 Apenas seis dias depois da visita de Donald Trump, o Presidente chinês, Xi Jinping, recebe o líder russo, Vladimir Putin, em Pequim. Os encontros realçam o papel crescente da China num panorama geopolítico fragmentado.
Momentul Chinei? Putin în vizită la Xi, imediat după Trump
Xin Lin 19.05.202619 mai 2026 La doar patru zile după ce l-a primit pe Donald Trump, Xi Jinping se pregătește să-l întâmpine pe Vladimir Putin. Întâlnirile evidențiază rolul tot mai important al Beijingului într-un peisaj geopolitic fragmentat.
Após Trump, Putin vai a Pequim cortejar Xi Jinping
19/05/202619 de maio de 2026 Encontros evidenciam posição influente da China num cenário geopolítico cada vez mais fragmentado e marcado por rivalidades entre as grandes potências.
Microsoft Cares About Your Privacy China's moment? Putin heads to Beijing after Trump courts Xi
Xin Lin Ostensibly, Russian President Vladimir Putin's visit to China this week to meet with his counterpart, Xi Jinping, is taking place to mark the 25th anniversary of the 2001 Sino‑Russian Treaty of Good‑Neighborliness and Friendly Cooperation. But the timing of the trip — just days after US President Donald Trump's state visit to Beijing — is noteworthy, and highlights China's influential position in a geopolitical landscape that is increasingly fractured and marked by great power rivalries.
Advances in chemoprevention of familial adenomatous polyposis
Abstract Familial adenomatous polyposis (FAP) is an autosomal dominant hereditary disease characterized by the early onset of numerous intestinal polyps, which, if untreated, may progress to colon cancer. Traditional treatments have primarily relied on surgical resection; however, with advancements in molecular biology and pharmacology, chemoprevention has increasingly become an important adjunct in the treatment of FAP.
Después de Trump, Putin viaja a China: qué busca ganar Moscú Original
Xin Lin 18/05/202618 de mayo de 2026 Días después de recibir a Donald Trump, Xi Jinping se prepara para reunirse con Vladimir Putin. El encuentro refleja el creciente peso de China en un escenario geopolítico cada vez más fragmentado. https://p.dw.com/p/5Dvp8 La última vez que Putin visitó China, en septiembre de 2025, Xi le dio la bienvenida como a un "viejo amigo".
China: Nach Trump kommt Putin
Xin Lin Am Dienstag (19.5.26) wird der russische Präsident Wladimir Putin in der chinesischen Hauptstadt erwartet. Es wird sein 25. Chinabesuch sein. Putin folgt unmittelbar auf US-Präsident Donald Trump, dervor einer Woche ebenfalls in Pekingwar. Offiziell wollen China und Russland 25 Jahre Freundschaftsvertrag feiern. Auf der Tagesordnung stehen aber auch bilaterale Wirtschafts- undHandelsfragensowie Gespräche über internationale und regionale Brennpunkte. China istRusslandsgrößter Handelspartner.
China's moment? Putin heads to Beijing after Trump courts Xi
Xin Lin Ostensibly, Russian President Vladimir Putin's visit to China this week to meet with his counterpart, Xi Jinping, is taking place to mark the 25th anniversary of the 2001 Sino‑Russian Treaty of Good‑Neighbourliness and Friendly Cooperation. But the timing of the trip — just days afterUS President Donald Trump's state visit to Beijing— is noteworthy, and highlights China's influential position in a geopolitical landscape that is increasingly fractured and marked by great power rivalries.
China's moment? Putin heads to Beijing after Trump courts Xi
Xin Lin 05/18/2026May 18, 2026 Just days after hosting Donald Trump, China's Xi Jinping is set to welcome Russian leader Vladimir Putin. The meetings underscore Beijing's growing, central role in a fractured geopolitical landscape.
China: Nach Trump kommt Putin
Xin Lin 18.05.202618. Mai 2026 Pekings wachsender Einfluss in einer zersplitterten Weltlage ist nicht zu übersehen. Nach Trump wird nun Putin diese Woche Chinas Präsident Xi treffen. Was erhofft er sich? https://p.dw.com/p/5DvST (Archiv) Putin und Xi am 3.9.2025 in Peking Am Dienstag (19.5.26) wird der russische Präsident Wladimir Putin in der chinesischen Hauptstadt erwartet. Es wird sein 25. Chinabesuch sein.
特朗普刚走，普京将至：中国的外交“高光时刻”？
Xin Lin 2026年5月18日2026年5月18日 美国总统特朗普刚刚结束访华，俄罗斯总统普京又将于周二抵达北京。当特朗普受到习近平的高规格接待，并看似轻松地离开北京后，普京此行期待达成的又是什么？ https://p.dw.com/p/5Du7d 普京上一次访华是去年9月参加阅兵式 （德国之声中文网）俄罗斯总统普京将于5月19日至20日访问北京，与中国国家主席习近平举行两天会谈。克里姆林宫表示，此访适逢《中俄睦邻友好合作条约》签署25周年，双方预计将重点讨论双边关系、经济合作，以及重大国际和地区问题。 普京此访紧随特朗普访华之后。柏林的墨卡托中国研究中心（MERICS）专家宋高祖（Claus Soong）向德国之声表示，当前地缘政治格局让北京处在一个相对有利的位置——如今，美国和俄罗斯都在不同程度上需要中国。 宋补充说，这也意味着北京目前无需在美国和俄罗斯之间作出明确选择，也不必急于同俄罗斯与西方的紧张关系切割。 当特朗普受到习近平的高规格接待，并看似轻松地离开北京后，普京此行则可能带有一层试探意味：他需要确认，中美关系的任何改善不会以牺牲莫斯科的利益为代价。...
Alkaline selective separation of silicon/vanadium from vanadium-bearing shale and recovery of silica
Abstract To overcome the lack of effective separation driving force in traditional physical pre-concentration methods for vanadium hosted in mica-type minerals, an alkaline selective pre-desilication route for silicon/vanadium separation was proposed based on the differences in reactivity and structural stability of various mineral phases in alkaline systems.
Computer Science > Computation and Language
arXivLabs is a framework that allows collaborators to develop and share new arXiv features directly on our website. Both individuals and organizations that work with arXivLabs have embraced and accepted our values of openness, community, excellence, and user data privacy. arXiv is committed to these values and only works with partners that adhere to them. Have an idea for a project that will add value for arXiv's community? Learn more about arXivLabs.
Linear RAG scanning mediates editing of Igκ variable region repertoires
Abstract V(D)J recombination-mediated Igκ light chain variable region exon assembly in precursor (pre)-B cells involves recombination activating gene (RAG) endonuclease-orchestrated cleavage between and joining of paired Vκ and Jκ gene segments and flanking RAG-targeting recombination signal sequences (RSSs)1,2,3. The 3.1-megabase Igk contains 4 Jκs (Jκ1, 2, 4, 5) and 100-plus Vκs in clusters oriented for deletional or inversional joining2.
Production of lactulose-containing sweet milk and yoghurt utilising cellobiose 2-epimerase from Caldicellulosiruptor bescii
Lin, X., Yan, M., Zhao, R., Qin, L., Lu, S., Hu, Y., Wang, T. and Xu, Z. (2026), Production of lactulose-containing sweet milk and yoghurt utilising cellobiose 2-epimerase from Caldicellulosiruptor bescii. Int J Dairy Technol, 79: e70109. https://doi.org/10.1111/1471-0307.70109 CONFLICTS OF INTEREST The authors declare no conflicts of interest. DATA AVAILABILITY STATEMENT The data that support the findings of this study are available upon request from the corresponding author.
从《天安门》到民间档案：一段由民间书写的历史
Xin Lin 2026年3月29日2026年3月29日 提起上世纪80年代的中国历史，你最先想到的是怎样一段过去，又是谁的过去？今年3月，民间档案机构“中国民间档案馆”在柏林举办了一场以时代记忆为主题的纪录片展，也为这个问题提供了另一个入口。 https://p.dw.com/p/5BFWp 柏林一家影院举办了一场由中国民间档案馆组织的纪录片影展 （德国之声中文网）鬓角、鼻孔、嘴唇—— 荧幕上，一只健硕的手紧握油画刷，在一张巨幅人像上来回涂抹。 低沉的钟声从远处推来。镜头逐渐拉远，灰色的天在屏幕尽头铺开，一张金色的毛泽东头像缓缓升起，定格在天安门城楼中央。 放映厅里，年轻华人与银发的德国老人交错而坐。 一行白色楷体字跃上画面：“我们尊重历史，正如我们尊重生命”。 没人说话，也没有人提前离开。 三月中旬，柏林一家影院举办了一场由中国民间档案馆组织的纪录片影展，放映了四部摄制于北京八十年代至九十年代初的影像作品。 曾获普利策国际报道奖（Pulitzer Prize）的美籍加拿大作家与记者张彦（Ian...
A critical role for STAT3 Thr714 phosphorylation in NPM-ALK-driven tumorigenesis
Abstract The oncogenic fusion protein NPM-ALK drives anaplastic large cell lymphoma (ALCL) by activating the transcription factor STAT3. While STAT3 phosphorylation at Y705 and S727 is well characterized, the present study defines a mechanistic role for phosphorylation at T714 in supporting full STAT3 functionality. In NPM-ALK–positive ALCL cells, STAT3 is phosphorylated at Y705, S727, and T714, and this is suppressed by ALK inhibition.
The cGAS-STING pathway in cancer: friend or foe
Abstract The cGAS-STING pathway is crucial for recognizing aberrant DNA in the cytoplasm and activating the innate immune response. After detecting aberrant DNA in the cytoplasm, cGAS can catalyze the synthesis of cGAMP from ATP and GTP, which acts as a second messenger to engage STING and unleash type I interferons, thereby eliciting a robust antitumor immune cascade. In recent years, the role of the cGAS-STING pathway in tumor immunity has attracted widespread attention.
Engineered Biomimetic Nanoparticles With Targeted Delivery of Chlorothiazide for the Treatment of Inflammatory Bowel Disease
Conflicts of Interest The authors declare no conflicts of interest. Data Availability Statement The data that support the findings of this study are available from the corresponding author upon reasonable request. Supporting Information Filename Description anie71740-sup-0001-SuppMat.docx8.1 MB Supporting File 1: anie71740-sup-0001-SuppMat.docx.
Pancreatic-targeted lipid nanoparticles based on organ capsule filtration - Nature
Abstract Achieving pancreatic-targeted delivery marks a breakthrough in treating pancreatic diseases, yet precise delivery remains challenging1. Here we identify an explicit and universal principle for pancreatic-selective delivery and propose a pancreatic-targeted lipid nanoparticle (AH-LNP) for mRNA delivery.
Trimodal single-cell profiling of transcriptome, epigenome and 3D genome in complex tissues with scHiCAR - Nature Biotechnology
Abstract The three-dimensional (3D) organization of cis-regulatory elements (CREs) is critical in transcription control. However, capturing transcriptome, epigenome and 3D genome from the same single cells remains challenging. Here we present scHiCAR (single-cell Hi-C with assay for transposase-accessible chromatin and RNA sequencing), a plate-based combinatorial barcoding method that simultaneously profiles mRNA, open chromatin and chromosome conformation capture from the same cells.
Efficacy and Safety of Punch Excision Combined With Adjuvant Therapies for Hypertrophic Scars and Keloids: A Narrative Review
1 Introduction The human organism possesses an inherent capacity for adaptive regeneration following injury [1]. However, excessive reparative processes can trigger the development of pathological scars—notably hypertrophic scars and keloids—which represent dysregulated healing phenotypes. Cutaneous wound-healing progresses through four sequential phases: hemostasis, inflammation, proliferation, and remodeling [2].
Progress in research on predictors of adverse outcomes in patients with nasal inflammatory diseases
Graphical Abstract. Schematic of predictors of adverse outcomes and targeted interventions in nasal inflammatory diseases.
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