Yee-Sin Leo on Muck Rack

Yee-Sin Leo

As seen in: Nature, PLOS, Medscape, Science Magazine
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Articles

Dengue infection elicits skin tissue-resident and circulating CD8 + T cells associated with protection from hospitalization

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By Zhen He, Yudai Sato, Sophie R Shoemaker, Ka-Wai Cheung, Valerie Chew, Michaela Gregorova, Eugenia Ziying Ong, Kuan Rong Chan, Tun-Linn Thein, Yee-Sin Leo, Eng Eong Ooi, Laura Rivino, Noor Zayanah Hamis, Justin SG Ooi
| Science Magazine
Abstract Dengue is spreading globally, and there is urgent need to define immune correlates of protection for this disease. Dengue infection first occurs in the skin following the bite of an infected mosquito; however, knowledge of host immune responses within this site remains sparse. We investigated the phenotypic, functional, and transcriptional profiles of skin and blood T cells in 73 patients with dengue and 10 healthy volunteers.
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Human MERS-CoV cases are falling but pose an ongoing pandemic threat

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By Lorenzo Subissi, James R. Otieno, Laith Jamal Abu-Raddad, Anurag Agrawal, Amal Z. Barakat, Leon Caly, Meera A Chand, Christian Drosten, Nuno R Faria, Adeola Fowotade, Anne von Gottberg, Bart L Haagmans, Baoying Huang, Jason Kindrachuk, Marion Koopmans, Bette Korber, Yee-Sin Leo, Placide Mbala-Kingebeni, Nada M Melhem, Vincent J. Munster, Isaac Ngere, M. Kariuki Njenga, Tulio de Oliveira, Gustavo Palacios, Malik Peiris, Andrew Rambaut, Paola Cristina Resende, Senjuti Saha, Tadaki Suzuki, Pragya D. Yadav, Sophie von Dobschuetz, Esam I Azhar, Maria Van Kerkhove, Ahmed Mohammed Albarraq, Ismail Mahat Bashir
| Nature
Human cases of Middle East respiratory syndrome coronavirus (MERS-CoV) have declined in recent years, but continued surveillance and research is needed to understand this trend and mitigate future zoonotic threats.
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Adult dengue vaccination in a low transmission setting: A modelling study in Singapore

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By Abhishek Senapati, Tun-Linn Thein, Yee-Sin Leo
| PLOS
Loading metrics Open Access Peer-reviewed Research Article ? This is an uncorrected proof. Citation: Senapati A, Thein T-L, Leo Y-S, Clapham HE (2026) Adult dengue vaccination in a low transmission setting: A modelling study in Singapore. PLoS Negl Trop Dis 20(3): e0014062. https://doi.org/10.1371/journal.pntd.0014062 Editor: Ahmed Hassan Fahal, University of Khartoum, SUDAN Received: August 18, 2025; Accepted: February 19, 2026; Published: March 2, 2026 Copyright: © 2026 Senapati et al.
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