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Articles by Yi Yan
Development and validation of a clinical prediction model for diagnosing nephrotic syndrome in adults: a retrospective diagnostic prediction study
Abstract Background: The high incidence of nephrotic syndrome (NS) in adults imposes a heavy burden on families and public health care systems, highlighting the significance of early and accurate diagnosis. Objectives: To develop and internally validate a predictive model and scoring system for diagnosing NS in adults.
Optimizing hydration in Chinese youth taekwondo athletes: evidence-based daily and training session-specific fluid intake recommendations
Abstract Background: Adequate hydration is crucial for athletic performance and health, particularly in adolescent athletes with distinct physiological demands. Comprehensive data on the daily and training-specific hydration status of populations like Chinese youth taekwondo athletes remain limited, hindering evidence-based strategy development. Objective: This study aimed to rigorously evaluate the daily and training session hydration status of taekwondo athletes in the Chinese youth team.
Loss of LCN2 Function Ameliorates Glucocorticoid-Induced Muscle Atrophy via Remodeling the Extracellular Matrix
1 Introduction Skeletal muscle atrophy is a common and severe complication caused by aging, chronic diseases, disuse, and long-term glucocorticoid (GC) exposure, and is characterized by muscle mass loss, impaired contractile function, and decreased motor performance [1-4].
Screening intrinsic ferroelastic altermagnets in NiAs-type monolayers with anomalous Hall conductivity, magnetoresistance, and elastoresistance
Abstract Coupling multiferroic orders with emerging altermagnetism offers a promising route toward multifunctional quantum devices. Here, we combine symmetry analysis, systematic density functional theory screening, and nonequilibrium Green’s function calculations to investigate 48 NiAs-type (110) monolayers. We identify a class of ferroelastic-altermagnetic biferroics exhibiting intrinsic coupling between lattice strain and spin order.
Pharyngeal Microenvironment Associated with Human Rhinovirus Infection in Children: Insights from Metatranscriptomic Sequencing
Abstract Human rhinovirus (HRV) is one of the most common causes of acute low respiratory tract infections (ALRTIs) in children and adults resulting in significant alterations in host gene expression and respiratory tract microbiome composition. We sought to clarify HRV prevalence features in children in Wuhan, and investigate interactions between HRV and host in pharynx microenvironment.
Non-canonical ceRNA-independent mechanism of the lncRNA-H19/miR-212-5p axis targeting KLF4 in Hcy-triggered VSMCs dysfunction and atherogenesis
Abstract Long non-coding RNAs (lncRNAs) and microRNAs (miRNAs) act as critical post-transcriptional regulators in the pathogenesis of atherosclerosis (As). However, the non-canonical regulatory mechanisms of lncRNAs and miRNAs, independent of the competing endogenous RNA (ceRNA) pathway, especially in homocysteine (Hcy)-induced vascular smooth muscle cells (VSMCs) dysfunction—a key event in As progression—remain largely unclear.
Construction of a comprehensive value assessment framework for renal denervation therapy: a decision-support tool for Chinese hospital management
Abstract Objective: Renal denervation (RDN) therapy is an innovative interventional therapy for patients with refractory hypertension and antihypertensive drug intolerance. In China, four RDN products were approved by National Medical Products Administration. This study aims to construct a comprehensive value assessment framework for RDN therapy to support the rational selection and application in Chinese hospitals.
Shared drone route scheduling optimization
Loading metrics Open Access Peer-reviewed Research Article Citation: Hong C, Yan Y, Lian Z, Li X (2026) Shared drone route scheduling optimization. PLoS One 21(5): e0348883. https://doi.org/10.1371/journal.pone.0348883 Editor: Zhihong (Arry) Yao, Southwest Jiaotong University, CHINA Received: April 28, 2025; Accepted: April 22, 2026; Published: May 19, 2026 Copyright: © 2026 Hong et al.
Unpacking the relationship between L2 grit profiles and foreign language engagement among Chinese university students
Ayuda Buscar en la ayuda Buscar en la ayuda Unpacking the relationship between L2 grit profiles and foreign language engagement among Chinese university students Sun, Wei [1] ; Yan, Yi [2] [1] Huazhong University of Science and Technology [2] China University of Petroleum Beijing Localización: Porta Linguarum: revista internacional de didáctica de las lenguas extranjeras, ISSN 1697-7467, Nº. 45, 2026 (Ejemplar dedicado a: January), págs.
Shunt configuration’s role in shaping hemodynamics of reverse Potts shunt in pediatric pulmonary arterial hypertension
ORIGINAL RESEARCH article Volume 13 - 2025 | https://doi.org/10.3389/fbioe.2025.1697468 1 Introduction Pulmonary arterial hypertension (PAH) is a progressive disease characterized by elevated pressure in the pulmonary artery, resulting in right heart failure and eventually death (Ivy et al., 2013). The median survival time of untreated PAH patients is only 2.8 years (D'Alonzo et al., 1991).
Cost-utility analysis of telitacicept versus belimumab in the treatment of systemic lupus erythematosus in China
Center for Health Policy and Technology Evaluation, Peking University Health Science Center, Beijing, China Objective: Telitacicept and belimumab are the only two approved biologics in China for treating systemic lupus erythematosus (SLE). With the widespread clinical use of biologics, more reliable clinical evidence has been provided.
Deep learning inversion method for canopy height Based on collaborative modelling of GEDI waveforms and geographic environmental factors
ABSTRACT Global Ecosystem Dynamics Investigation (GEDI) waveform data are highly susceptible to noise and traditional algorithms struggle to account for the influence of geographic environmental factors in forest canopy height estimation.
MicroRNA Lse‐miR‐2944c‐3p regulates female reproduction in Lasioderma serricorne by targeting the heat shock protein LsHSP70‐3
CONFLICT OF INTEREST The authors declare that they have no conflicts of interest with the contents of this article. Supporting Information Filename Description ps70352-sup-0001-TableS1.docxWord 2007 document , 14.2 KB Table S1. Primers used in the study. REFERENCES 1, Structure of the ovary in Nannochorista neotropica Navás (Insecta: Mecoptera: Nannochoristidae) with remarks on mecopteran phylogeny. Acta Zool 83: 61–66 (2002).
Programmable Electromagnetic Switching in Shape‐Memory‐Driven Liquid Metal/Polyimide/Aramid Nanofiber Aerogels for Intelligent Wave Management
Conflict of Interest The authors declare no conflict of interest. Supporting Information Filename Description adfm72551-sup-0001-SuppMat.docx2.1 MB Supporting Information References 1, , , , , , , , , Adv. Funct. Mater. 2023, 33, 2211352. 2, , , , , , , , , , Chem. Eng. J. 2025, 506, 160008. 3, , , , , , , , , , Adv. Funct. Mater. 2025, 35, 2418257. 4, , , , , , , , , , Adv. Colloid Interface Sci. 2025, 335, 103336. 5, , , , Nano Res. 2022, 15, 6751. 6, , , , , , , , Small 2025, 21, 2408366.
Inbreeding depression in the predatory mite Stratiolaelaps scimitus: demographic and transcriptomic insights
DATA AVAILABILITY STATEMENT The data that support the findings of this study are available on request from the corresponding author. The data are not publicly available due to privacy or ethical restrictions.
Constructing regional catchment-specific triggering threshold for runoff-generated debris flows: a case study in the Bailong River
?Mathematical formulae have been encoded as MathML and are displayed in this HTML version using MathJax in order to improve their display. Uncheck the box to turn MathJax off. This feature requires Javascript. Click on a formula to zoom. Abstract Constructing catchment-specific rainfall thresholds is crucial for high-accuracy debris flow forecasting.
Cavity Structure Evolution Based on Asymmetric Diffusion for Efficient Electromagnetic Wave Absorption
Conflict of Interest The authors declare no conflict of interest. Supporting Information Filename Description adfm72275-sup-0001-SuppMat.docx21.9 MB Supporting Information References 1, , , , , , , Adv. Mater. 2025, 37, 2501302. 2, , , , , , Small Struct. 2023, 4, 2200219. 3, , , , , , , , Chem. Eng. J. 2025, 520, 165960. 4, , , , , , Carbon 2025, 235, 120095. 5, , , , , , , , , , , Nat. Commun. 2024, 15, 1497. 6, , , , , , , , Adv. Funct. Mater. 2025, 202512806. 7, , , , , , , , , , Chem. Eng. J. 2025, 519, 165016.
Host Immune Response to Respiratory Syncytial Virus Infection in Children
Conflicts of Interest The authors declare no conflicts of interest. References 1, , and , “Recovery of Cytopathogenic Agent From Chimpanzees With Coryza,” Proceedings of the Society for Experimental Biology and Medicine 92 (1956): 544–549. 2, , , et al., “Causes of Severe Pneumonia Requiring Hospital Admission in Children Without HIV Infection From Africa and Asia: The PERCH Multi-Country Case Control Study,” Lancet 394 (2019): 757–779.
Alkoxy‐Substituted Anthrabis(Thiadiazole)‐Terthiophene Copolymers for Organic Photovoltaics: A Unique Wavy Backbone Enhances Aggregation, Molecular Order, and Device Efficiency
1 Introduction Nonfullerene organic photovoltaic cells (NF-OPVs) composed of wide-bandgap polymer donors and narrow-bandgap small molecular acceptors (SMAs) have seen remarkable advancements in recent years.[1] In particular, the rapid development of various SMAs, such as the Y6 and Y12 series (Figure 1A), has significantly boosted the power conversion efficiencies (PCEs) of NF-OPVs beyond 20% at the laboratory scale.[2-6] However, despite these advances, reports on high-performance polymer...
AI Learning for Pediatric Right Ventricular Assessment: Development and Validation Across Multiple Centers
BJ, YL, QT, and SZ are employees of HBI Solutions Inc. NO and TI are Stanford University visiting scholars from Nippon Life Insurance Company. However, the companies had no role in the design of the study, data collection, data analysis, interpretation, or the preparation of this manuscript. All research and experimental work were conducted independently, and no external influence impacted on the study's findings or conclusions.
Trp31 Residue of Trx-1 Is Essential for Maintaining Antioxidant Activity and Cellular Redox Defense Against Oxidative Stress
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Can Exercise-Mediated Adipose Browning Provide an Alternative Explanation for the Obesity Paradox?
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Roles of Vitellogenin and Its Receptor Genes in Female Reproduction of the Cigarette Beetle, Lasioderma serricorne
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Vinylene‐Bridged Alkoxyfluorobenzothiadiazole (FOBTzE)‐Based Semiconducting Polymers for Enhanced Performance in Non‐Fullerene Organic Photovoltaic Cells
Supporting Information Filename Description pol20241036-sup-0001-supinfo.pdfPDF document, 758.5 KB Data S1. Supporting Inforamtion. References 1, , and , “Recent Progress in Flexible–Wearable Solar Cells for Self-Powered Electronic Devices,” Energy & Environmental Science 13 (2020): 685–743. 2, , , et al., “Recent Progress in Flexible and Stretchable Organic Solar Cells,” Advanced Functional Materials 30 (2020): 2002529.
Hybrid GRU-Random Forest Model for Accurate Atmospheric Duct Detection with Incomplete Sounding Data
1. Introduction The troposphere, the lowest layer of Earth’s atmosphere, is influenced by a variety of weather processes, both random and systematic, which complexly affect the atmospheric state (temperature, pressure, humidity, etc.) and transport (waves, ozone, etc.) [1,2,3,4]. These variations significantly alter the atmospheric refractive index, a key factor in how light and radio waves travel through the air [5,6].
Double Braking Effects of Nanomedicine on Mitochondrial Permeability Transition Pore for Treating Idiopathic Pulmonary Fibrosis
1 Introduction Idiopathic pulmonary fibrosis (IPF) is a rapidly progressive and fatal alveolar disease with a median survival rate of 2–3 years.[1] It is characterized by the excessive proliferation of fibroblasts, the excessive extracellular matrix deposition and the destruction of alveolar structure.[2] According to World IPF Joint Association data, ≈1.22 million new cases are suffering from IPF every year.[3] Environmental pollution, viral infections, and smoking are recognized as the...
Electron Migratory Polarization of Interfacial Electric Fields Facilitates Efficient Microwave Absorption
Conflict of Interest The authors declare no conflict of interest. Supporting Information Filename Description adfm202416727-sup-0001-SuppMat.docx3.2 MB Supporting Information References 1a) , , , , , , , , Acs Appl Mater Inter. 2019, 11, 44536; b) , , , , , , , , , , , , Acs Appl Mater Inter. 2019, 11, 18626; c) , , , , Adv. Sci. 2024, 11, 2307649. 2a) , , , , , , , , , , ACS Nano. 2021, 15, 6622; b) , , , , , Adv. Funct. Mater. 2022, 32, 2204499; c) , , , , , , , , Cell Rep Phys Sci 2024, 5, 102097.
Characterization and Modeling of Out-of-Plane Behavior of Fiber-Based Materials: Numerical Illustration of Wrinkle in Deep Drawing
1. Introduction Fiber materials such as paper and paperboard play an indispensable role in numerous industrial applications such as printing, packaging, and construction. Paperboard is a fibrous material consisting primarily of wood pulp and can be produced as single-ply or multi-ply paperboard, depending on the end use. Multi-ply paperboard is more widely used because of the higher basis weights usually required for practical processing.
Study of Manipulative Pore Formation upon Polymeric Coating for the Endowment of the Switchable Property between Passive Daytime Radiative Cooling and Heating
Applications of Polymer, Composite, and Coating MaterialsAugust 9, 2024 Pengcheng Cui Department of Materials Science and Engineering, School of Materials Science and Chemical Engineering, Ningbo University, Ningbo 315211, China Yi Yan Department of Materials Science and Engineering, School of Materials Science and Chemical Engineering, Ningbo University, Ningbo 315211, China Hao Wei Department of Materials Science and Engineering, School of Materials Science and Chemical Engineering, Ningbo...
3년불사용취소 안건중 상품의 용도및 명칭의 게임
지식재산권 분야에서 3년불사용취소안건은 상표권리유지와 취소의 중요한 전쟁터가 된다.이 과정에서 사용증거의 제공과 인정은 매우 중요하다.특히 상품의 용도와 명칭에 대한 정확한 확정에 중요하다.본문은 당소 대리한 대표적인 3년불사용취소안건을 통해 상품의 용도와 명칭이 상표권분쟁에서의 중요성과 그 게임 과정을 연구하고 경험과 교훈을 총결하여 관련자에게 유익한 참고를 되기를 바란다.
vB_CacS-HV1 as a Novel Pahexavirus Bacteriophage with Lytic and Anti-Biofilm Potential against Cutibacterium acnes
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Facile Preparation of Multifunctional Hydrogels with Sustained Resveratrol Release Ability for Bone Tissue Regeneration
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Toxics | Free Full-Text | Tris (2-chloroisopropyl) phosphate and Tris (nonylphenyl) phosphite Promote Human Renal Cell Apoptosis through the ERK/CEPBA/Long Non-Coding RNA Cytoskeleton Regulator Axis
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Source Models of the 2016 and 2022 Menyuan Earthquakes and Their Tectonic Implications Revealed by InSAR
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Effects of miR-306 Perturbation on Life Parameters in the English Grain Aphid, Sitobion avenae (Homoptera: Aphididae)
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Disruption of microRNA pathway core genes inhibits molting and reproduction of the cigarette beetle, Lasioderma serricorne
Supporting Information Filename Description ps8158-sup-0001-FigureS1.docxWord 2007 document , 657.6 KB Figure S1. Phylogenetic analysis of six miRNA pathway proteins in different insects. Evolutionary relationships between Dicer-1, Argonaute-1, Drosha, Pasha, Exportin-5, and Loquacious proteins were drawn using the neighbor-joining method. Lasioderma serricorne miRNA pathway proteins are pointed out by red triangles. ps8158-sup-0002-TableS1.docxWord 2007 document , 21.6 KB Table S1.
[2405.04111] Adaptive Least Mean pth Power Graph Neural Networks
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Microorganisms | Free Full-Text | Metagenomic and Culturomics Analysis of Microbial Communities within Surface Sediments and the Prevalence of Antibiotic Resistance Genes in a Pristine River: The Zaqu River in the Lancang River Source Region, China
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Malignant Gastrointestinal Neuroectodermal Tumor (GNET) Mimicking Small Bowel Lymphoma: A Case Report
Specialty Please choose I'm not a medical professional. Allergy and Immunology Anatomy Anesthesiology Cardiac/Thoracic/Vascular Surgery Cardiology Critical Care Dentistry Dermatology Diabetes and Endocrinology Emergency Medicine Epidemiology and Public Health Family Medicine Forensic Medicine Gastroenterology General Practice Genetics Geriatrics Health Policy Hematology HIV/AIDS Hospital-based Medicine I'm not a medical professional.
Deletion of Tgm2 suppresses BMP‐mediated hepatocyte‐to‐cholangiocyte metaplasia in ductular reaction
1 INTRODUCTION The hepatic epithelial tissue, composed of hepatocytes and cholangiocytes, is normally inactive under physiological conditions, but exhibits vigorous proliferation and adaptability in response to different injuries, thus contributing to the liver's extraordinary regenerative ability.1, 2 Upon cholestatic liver injury, the liver parenchyma experiences the ectopic emergence and expansion of atypical biliary epithelial cells (BECs), commonly referred to as ductular reaction (DR),...
Mechanism of KDM5A‐mediated H3K4me3 modification in the osteogenic differentiation of mesenchymal stem cells in steroid‐induced osteonecrosis of the femoral head
Steroid-induced osteonecrosis of the femoral head (SONFH) is characterized by impaired osteogenesis in bone marrow mesenchymal stem cells (BMSCs). This study investigates the role of lysine-specific demethylase 5A (KDM5A) in SONFH to identify potential therapeutic targets. Human BMSCs were isolated and characterized for cell surface markers and differentiation capacity. A SONFH cell model was established using dexamethasone treatment.
Myogenic exosome miR-140-5p modulates skeletal muscle regeneration and injury repair by regulating muscle satellite cells
Research Paper Volume 16, Issue 5 pp 4609—4630 1 College of Veterinary Medicine, Shanxi Agricultural University, Taigu, Shanxi 030801, China 2 Department of Nephrology, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200080, China https://doi.org/10.18632/aging.205617 How to Cite Cite this Article Select the format you require from the list below Click to copy this citation from the text box above or download the citation: Citation | Copyright: © 2024 Cao...
Myogenic exosome miR-140-5p modulates skeletal muscle regeneration and injury repair by regulating muscle satellite cells
Introduction Skeletal muscle, an essential component of the human body, plays a crucial role in various functions, such as movement, metabolism, and endocrine regulation. Its regenerative capacity and plasticity rely on muscle satellite cells found within the skeletal muscle [1–3]. In the event of muscle injury, these quiescent satellite cells become activated, entering the cell cycle, proliferating, and differentiating to repair the damaged muscle and replenish the cell pool [4–6].
Identification of a non-canonical chemokine-receptor pathway suppressing regulatory T cells to drive atherosclerosis - Nature Cardiovascular Research
Abstract CCL17 is produced by conventional dendritic cells, signals through CCR4 on regulatory T (Treg) cells and drives atherosclerosis by suppressing Treg functions through yet undefined mechanisms. Here we show that conventional dendritic cells from CCL17-deficient mice display a pro-tolerogenic phenotype and transcriptome that is not phenocopied in mice lacking its cognate receptor CCR4. In the plasma of CCL17-deficient mice, CCL3 was the only decreased cytokine/chemokine.
A Humeral Osteosarcoma Mimicking Osseous Leiomyosarcoma: A Case Report
Specialty Please choose I'm not a medical professional. Allergy and Immunology Anatomy Anesthesiology Cardiac/Thoracic/Vascular Surgery Cardiology Critical Care Dentistry Dermatology Diabetes and Endocrinology Emergency Medicine Epidemiology and Public Health Family Medicine Forensic Medicine Gastroenterology General Practice Genetics Geriatrics Health Policy Hematology HIV/AIDS Hospital-based Medicine I'm not a medical professional.
Какво е реалното население на Китай? - What Is the Real Population of China?
(Minghui.org) The Chinese Communist Party (CCP) published its 2023 population survey results on January 17, 2024, claiming the country has 1.409 billion citizens, which is 0.15% or 2.08 million fewer inhabitants compared to 2022. But Lingxiao (pseudonym) of Nanjing City, Jiangsu Province, told The Epoch Times that, based on what he learned from someone inside the communist regime, many people in China died during the pandemic so the population couldn’t possibly be 1.409 billion.
Nanomedicines Promote Cartilage Regeneration in Osteoarthritis by Synergistically Enhancing Chondrogenesis of Mesenchymal Stem Cells and Regulating Inflammatory Environment
Download Hi-Res ImageDownload to MS-PowerPointCite This:ACS Nano 2024, XXXX, XXX Terms & Conditions Most electronic Supporting Information files are available without a subscription to ACS Web Editions. Such files may be downloaded by article for research use (if there is a public use license linked to the relevant article, that license may permit other uses).
Rapid genotyping of bovine MC1R gene c.296T>C and c.310delG haplotypes using high‐resolution melting analysis
No abstract is available for this article. CONFLICT OF INTEREST STATEMENT The authors declare no conflict of interest. REFERENCES , , , & (1995) The role of melanocyte-stimulating hormone (MSH) receptor in bovine coat color determination. Mammalian Genome, 6(9), 636–639. , , & (2007) Simultaneous mutation scanning and genotyping by high-resolution DNA melting analysis. Nature Protocols, 2, 59–66.
Pseudorabies virus causes splenic injury via inducing the oxidative stress and apoptpsos related factors in mice
Abstract This study was conducted to investigate the effects of pseudorabies virus (PRV) infection on the spleen of mice. Six-week-old BALB/c mice were grouped into two: i.e The treatment group which was subcutaneously injected with 200 μL of 1×103 TCID50/100μL dose of PRV and mice in the control received a subcutaneous injection of equal volumes of PBS. The spleen tissue samples were collected at various post-infection time points (48 h, 72 h, and 96 h) for further analysis.
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