Dan Hou
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Articles by Dan Hou
PnMYB4a, a R2R3 transcription factor, modulates coumarin biosynthesis during melanization in the culms of Phyllostachys nigra
Data availability The RNA-seq raw data used in this study were deposited in the NCBI's Gene Expression Omnibus (GEO), and are accessible through GEO Series accession no. GSE319742 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE319742). Supporting Information Filename Description nph71642-sup-0001-Supinfo.pdfPDF document, 1.8 MB Fig. S1 Analysis of the selected phenolics in Pn and Pnh. Fig. S2 Transcriptomic data of Pn and Pnh. Fig.
When does debt become a burden? Evidence from Asian developing countries
Abstract This study investigates the critical debt-to-GDP threshold at which external debt transitions from growth-enhancing to growth-impeding across 32 Asian developing economies over the period 1995–2020.
The impact of antidiabetic drugs on dementia risk: a Bayesian network meta-analysis
Abstract Background: Diabetes is significantly associated with cognitive impairment, particularly the risk of developing dementia. However, the impact of antidiabetic drugs on dementia risk remains unclear. This study aims to comprehensively evaluate the effects of different antidiabetic drugs on dementia risk using Bayesian network analysis.
A Self-Assembling Nanomodulator for Synergistic Therapy of Intracerebral Hemorrhage
Back to Journals » International Journal of Nanomedicine » Volume 21 Authors Yun T, Hou D, Hu Y, Fan Y, Zhang S, Wu T , You Y Received 9 January 2026 Accepted for publication 13 March 2026 Published 16 March 2026 Volume 2026:21 Pages 1—15 DOI https://doi.org/10.2147/IJN.S590652 Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 3 Editor who approved publication: Professor Eng San Thian Tian Yun,1,2,* Dan Hou,2,* Yujie Hu,2 Yonghao Fan,3 Shun...
Neurotrophin NGF/TrkA and BDNF/TrkB signaling orchestrates the immune microenvironment in osteosarcoma
1 Introduction Osteosarcoma is a high-grade primary bone malignancy in which therapeutic progress has been limited by intratumoral heterogeneity and an immunosuppressive tumor microenvironment (1–3). Initially defined as regulators of neuronal development and nerve–tumor interactions, neural mediators including neurotrophins and their receptors are now recognized as drivers of tumor progression, host immunity and, via oncogenic Trk fusions, cancer therapy.
Myristoylation of TMEM106B by NMT1/2 regulates TMEM106B trafficking and turnover
Keywords TMEM106B Myristoylation Lysosome NMT1/2 Introduction Transmembrane protein 106B (TMEM106B) has been linked to many brain disorders and brain aging. A large genome-wide association study (GWAS) attempting to identify risk factors for frontotemporal lobar degeneration (FTLD) with TDP43 inclusions uncovered TMEM106B, a protein with unknown function at the time (1).
SIRT2 Mediates Integrated Stress Response by Deacetylating and Stabilizing 4EBP1 to Suppress Translation
Abstract The ability to alleviate nutrient stress, such as amino acid limitation, is crucial for cell survival. The mTORC1 complex and integrated stress response (ISR) are mechanisms that sense the availability of amino acids and regulate ribosomal protein synthesis. Here we have discovered a new SIRT2-mediated pathway, downstream of ISR, that senses the limitation of amino acids to regulate translation.
Correction: Intersecting paths: Corporate and green innovation in Chinese firms-A penal cointegration analysis
The word "penal" is misspelled in the article title. The correct title is: Intersecting paths: Corporate and green innovation in Chinese firms—A panel cointegration analysis. The correct citation is: Liu Z, Hou D, Zahid RMA (2024) Intersecting paths: Corporate and green innovation in Chinese firms—A panel cointegration analysis. PLoS ONE 19(1): e0295633.
Mining and Expression Pattern Analysis of Genes Related to the Regulation of Flowering in Korean Pine (Pinus koraiensis)
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Computer-aided Design for Peptide in Cancer Therapeutics: A Bibliometr
Dan Hou,1– 3,* Haobin Zhou,1,2,* Yuting Tang,1,2 Ziyuan Liu,1,2 Lin Su,1,2 Junkai Guo,1,2 Janak Lal Pathak,1,2 Lihong Wu1,2 1Department of Basic Oral Medicine, School and Hospital of Stomatology, Guangdong Engineering Research Center of Oral Restoration and Reconstruction, Guangzhou Medical University, Guangzhou, Guangdong, 510182, People’s Republic of China; 2Guangzhou Key Laboratory of Basic and Applied Research of Oral Regenerative Medicine, Guangzhou, Guangdong, 510182, People’s...
Multidimensional ultrashort optical pulse manipulation using spatial light modulation
Ultrashort optical pulse manipulation is one of the key techniques for applications such as high-speed imaging and high-precision laser processing. In this study, we demonstrate the multidimensional manipulation of ultrashort optical pulses by integrating spatial dispersion and spatial light modulation.
Aerodynamic Effects of Time-Varying Corrugations on Dragonfly Wings in Flapping Flight
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Optofluidic time‐stretch imaging flow cytometry with a real‐time storage rate beyond 5.9 GB/s
CONFLICT OF INTEREST STATEMENT The authors declare no conflicts of interest. Supporting Information Filename Description cytoa24854-sup-0001-supinfo.docxWord 2007 document , 28.4 KB Data S1. Supporting Information. REFERENCES 1, , , , . Label-free multiphoton imaging flow cytometry. Cytometry A. 2023; 103(7): 584–592. 2, , . An imaging flow cytometry protocol for studying immunoregulatory receptor-mediated regulation of phagocytosis. Methods Mol Biol. 2022; 2421: 201–216. 3, , , , , , et al.
SMARCA5 reprograms AKR1B1-mediated fructose metabolism to control leukemogenesis
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NLRP3 Cys126 palmitoylation by ZDHHC7 promotes inflammasome activation
Highlights • NLRP3 Cys126 is palmitoylated by ZDHHC7 in macrophages • ZDHHC7-mediated NLRP3 Cys126 palmitoylation is critical for NLRP3 TGN localization • Cys126 palmitoylation is vital for recruiting ASC and inflammasome assembly • Cys126 palmitoylation promotes inflammasome activation in macrophages and in vivo Summary Nucleotide oligomerization domain (NOD)-like receptor protein 3 (NLRP3) inflammasome hyperactivation contributes to many human chronic inflammatory diseases, and...
Intersecting paths: Corporate and green innovation in Chinese firms-A penal cointegration analysis
Loading metrics Open Access Peer-reviewed Research Article Citation: Liu Z, Hou D, Zahid RMA (2024) Intersecting paths: Corporate and green innovation in Chinese firms—A penal cointegration analysis. PLoS ONE 19(1): e0295633.
NLRP3 Cys126 palmitoylation by ZDHHC7 Promotes Inflammasome Activation
Abstract NACHT-, leucine-rich-repeat- (LRR), and pyrin domain-containing protein 3 (NLRP3) mediates inflammasome activation in response to multiple pathogen and damage-associated molecular patterns in macrophages. Hyperactivation of NLRP3 inflammasome contributes to many human chronic inflammatory diseases. Understanding how NLRP3 inflammasome is regulated can potentially provide new strategies to treat inflammatory diseases.
The Paracrine Effect of Hyaluronic Acid-Treated Endothelial Cells Promotes BMP-2-Mediated Osteogenesis
1. Introduction Bone morphogenetic protein-2 (BMP-2) is a commonly used osteogenic factor for bone tissue regeneration [,]. However, excessive doses of BMP-2 are associated with several major unintended side effects that can seriously damage patients’ health and musculoskeletal functions, such as ectopic bone formation, paralysis, osteosarcoma growth, and neurological disturbances [,,]. Osteogenesis, angiogenesis, and their coupling are highly crucial for bone regeneration [,,].
Mechanical Behavior of Honeybee Forewing with Flexible Resilin Joints and Stripes
Open AccessArticle by 1 and 2,* 1 Department of Mechanical Engineering, Shanghai Maritime University, Shanghai 201306, China 2 School of Science, Harbin Institute of Technology, Shenzhen 518055, China * Author to whom correspondence should be addressed.
An intramolecular vibrationally excited intermolecular potential energy surface and predicted 2OH overtone spectroscopy of H2O-Kr
An intramolecular vibrationally excited intermolecular potential energy surface and predicted 2OH overtone spectroscopy of H2O-Kr A new five-dimensional potential energy surface (PES) for H2O-Kr which explicitly includes the intramolecular 2OH overtone state of the H2O monomer is presented. The intermolecular potential energies were evaluated at the explicitly correlated coupled cluster theory [CCSD(T)-F12] with a large basis set.
Animals | Free Full-Text | Transcriptome-Based Identification of the Muscle Tissue-Specific Expression Gene CKM and Its Regulation of Proliferation, Apoptosis and Differentiation in Chicken Primary Myoblasts
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Analysis of Differentially Expressed Unigenes Involved in the Development of Korean Pine (Pinus Koraiensis Sieb. ET Zucc.)
Abstract Korean pine is a monoecism gymnosperm that predominantly exists as both female and male. Due to the absence of a model organism reference genome, high-throughput sequencing was used to analyze the candidate unigenes of tissue and organ development. This was performed in the tissues of microstrobilli (Ms), needles (Ne), and mixed buds (Mb) of the Korean pine to mine for genes related to bud differentiation and flowering.
Identification of Structural Differentiation and Differentially Expressed Genes between Sulcus and Culm of Phyllostachys violascens cv. Viridisulcata
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Advantageous Strain Sensing Performances of FBG Strain Sensors Equipped with Planar UV-Curable Resin
This is an early access version, the complete PDF, HTML, and XML versions will be available soon.
Entailing the Next-Generation Sequencing and Metabolome for Sustainable Agriculture by Improving Plant Tolerance
Open AccessReview by Muhammad Furqan Ashraf 1,†, Dan Hou 1,†,‡, Quaid Hussain 1,‡, Muhammad Imran 2, Jialong Pei 1, Mohsin Ali 3, Aamar Shehzad 4, Muhammad Anwar 5, Ali Noman 6, Muhammad Waseem 2 and Xinchun Lin 1,* 1 State Key Laboratory of Subtropical Silviculture, Zhejiang A&F University, 666 Wusu Street, Lin’An, Hangzhou 311300, China 2 Colleges of Agriculture and Horticulture, South China Agricultural University, Guangzhou 510642, China 3 State Key Laboratory of Microbial Resources,...
Validation of the Australian Pelvic Floor Questionnaire in Chinese pregnant and postpartum women
To view the full text, please login as a subscribed user or purchase a subscription. Click here to view the full text on ScienceDirect. Fig. 1 Study process of the Australian Pelvic Floor Questionnaire (APFQ) Fig. 2 Bland-Altman plot: Representation of the difference in total questionnaire score of test and retest based on mean score(n = 24), and the limits of agreement (mean±1.96 standard deviations).
A General Interfacial Self‐Assembly Engineering for Patterning Two‐Dimensional Polymers with Cylindrical Mesopores on Graphene
Communication A General Interfacial Self‐Assembly Engineering for Patterning Two‐Dimensional Polymers with Cylindrical Mesopores on Graphene Yiyong Mai Corresponding Author E-mail address: mai@sjtu.edu.cn Shanghai Jiao Tong University, School of Chemistry and Chemical Engineering, 800 Dongchuan Road, 200240 Shanghai, CHINA Search for more papers by this author PDF PDF Share Abstract Free‐standing two‐dimensional (2D) porous nanomaterials have attracted considerable interest as ideal...
How Designers And Developers Can Work With A President Who Doesn’t Tru
For people who work at the intersection of technology and government, Trump’s presidency is a source of deep uncertainty. After all, President Obama was the biggest champion of digital innovation to ever reside in the White House. His administration appointed the first U.S. CTO, lured Silicon Valley talent to Washington, and supported open data and government transparency.
How Designers And Developers Can Work With A President Who Doesn’t Trust Technology
For people who work at the intersection of technology and government, Trump’s presidency is a source of deep uncertainty. After all, President Obama was the biggest champion of digital innovation to ever reside in the White House. His administration appointed the first U.S. CTO, lured Silicon Valley talent to Washington, and supported open data and government transparency.
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