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deepika sharma

As seen in: Cell Press, Journal of Electrical and Computer Engineering, Emerald Publishing, emerald insight, The Journal of Clinical Investigation, Supply Chain Management Review, International Journal Of Nursing Education And Research

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Articles

A myeloid Tet2-IL-1β axis modulates intestinal inflammation by restricting catecholaminergic stimulation of enterochromaffin cell differentiation

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By deepika sharma, Ankit Malik, Veronica Locher, Shaina McGrath, Sarah Zabala, Hardik Grover, Cezary Ciszewski, Li Chen, Daping Yang, Isaac M. Chiu, Bana Jabri
| Cell Press Verified
Keywords inflammatory bowel diseases macrophages IL-1 enterochromaffin cells catecholaminergic neurons intestinal inflammation Get full text access Log in, subscribe or purchase for full access. References 1. Smillie, C.S. ∙ Biton, M. ∙ Ordovas-Montanes, J. ... Intra- and Inter-cellular Rewiring of the Human Colon during Ulcerative Colitis Cell. 2019; 178:714-730.e22 2. Kong, L. ∙ Pokatayev, V. ∙ Lefkovith, A. ...
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Glutathione limits RUNX2 oxidation and degradation to regulate bone formation

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By JCI Insight, Guoli Hu, Yilin Yu, deepika sharma
| The Journal of Clinical Investigation
ResearchIn-Press PreviewBone biology Open Access | 10.1172/jci.insight.166888 JCI Insight. https://doi.org/10.1172/jci.insight.166888. Copyright © 2023, Hu et al. This work is licensed under the Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. View PDF Abstract Reactive oxygen species (ROS) are natural products of mitochondrial oxidative metabolism and oxidative protein folding.
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TNF/TNFR axis promotes pyrin inflammasome activation and distinctly modulates pyrin inflammasomopathy

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By deepika sharma, Ankit Malik, Clifford S Guy, Peter Vogel
| The Journal of Clinical Investigation
TNF promotes pyrin expression and inflammasome activation. To investigate the role of TNF signaling in pyrin inflammasome activation, we stimulated WT, Tnf–/–, and Tnfr1–/– Tnfr2–/– BM-derived macrophages (BMDMs) with Clostridium difficile toxin B, a canonical pyrin-activating stimulus (7).
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