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Dinis Pedro Calado

As seen in: Cell Press, Cell Reports
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Articles

Constitutive DUSP2 expression enhances lymphoid cell proliferation by activating CDK1 and promotes lymphomagenesis

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By Yu Qian, Jutatip Panaampon, Bjoern Chapuy, Xueyan Zhang, Xiujuan Zhao, Zhe Wang, Pengfei Zhang, Qiang Ke, Jing Zhong, Ping Yuan, Lei Zhang, Min Hong, Il-Kyu Choi, Jiankun Guan, Dinis Pedro Calado, Scott J. Rodig, Olga Pozdnyakova, Klaus Rajewsky, Susana Godinho, Siwanon Jirawatnotai, Hao Wu, Margaret A. Shipp, Stephanie K Dougan, Baochun Zhang, Tongchai Payungwong, Aretina Zhang
| Cell Reports Verified
Keywords DUSP2, PAC-1 immune cell hematologic malignancies lymphomagenesis cell cycle CDK1 CDC25 Research topic(s) CP: Cancer CP: Immunology Introduction Dual-specificity phosphatases (DUSPs) are a subset of protein tyrosine phosphatases that can dephosphorylate both tyrosine and serine/threonine residues. In humans, the DUSP family comprises 23 members.
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Nociceptive innervation limits tertiary lymphoid structures to promote lung cancer

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By Ya-Hsuan Ho, Giacomo Bregni, Marco Stazi, Paola Peinado, Pei-Hsing Chen, Claudio Ballabio, Victoire Boulat, Shree Vadera, Yilin Guan, Zhikai Liu, Alicia Alonso de la Vega, Li Wang, Chao-Chi Ho, Henrique Veiga-Fernandes, Julian Downward, Min-Shu Hsieh, Maksym V. Kopanitsa, George Kassiotis, Christoforos Tsantoulas, Michael S. Schappe, Dinis Pedro Calado, Isaac M. Chiu, Charles Swanton, Jin-Shing Chen, Leanne Li, Michael-Bogdan Margineanu
| Cell Press Verified
Results We first performed a stage-wise characterization of the innervation landscape in a GEMM of LUAD (Ad5-Spc-Cre, KrasLSL-G12D/+, Trp53fl/fl; Rosa26LSL-tdTomato [KP] model), which recapitulates the LUAD tumorigenesis process observed in patients.26 Staining for the pan-neuronal marker β3-tubulin revealed that pulmonary innervation in the normal lung is mainly concentrated in the large airways (Figures 1A and S1A).
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By Maryaline Coffre, David Benhamou, Lili Blumenberg, Valentina Snetkova, Dan R. Littman, Dinis Pedro Calado, David Rieß, Marcus J. Hines, Tirtha Chakraborty, Sofia Bajwa, Kari Jensen, Mark M. W. Chong, Lelise Getu, Gregg J. Silverman, Robert Blelloch, Doron Melame
| secure.jbs.elsevierhealth.com
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